chlorpromazine and hydrochlorothiazide

chlorpromazine has been researched along with hydrochlorothiazide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199013 (43.33)18.7374
1990's0 (0.00)18.2507
2000's7 (23.33)29.6817
2010's9 (30.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Baur, G; Kurz, H; Trunk, H1
Phillips, WA; Ratchford, JM; Schultz, JR1
Gershon, S; Shopsin, B1
Mikhaĭlin, SE1
Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC1
Kurz, H; Trunk, H1
Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C1
Moore, DE; Tamat, SR1
Halawa, B1
THURAU, K1
ZELCER, I1
FOFT, JW; WILLIAMS, RJ1
SJOEBERG, A1

Reviews

2 review(s) available for chlorpromazine and hydrochlorothiazide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Treatment of arterial hypertension in elderly patients].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Aug-15, Volume: 34, Issue:16

    Topics: Age Factors; Aged; Antihypertensive Agents; Chlorpromazine; Diazoxide; Dihydralazine; Drug Therapy, Combination; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Spironolactone

1981

Trials

1 trial(s) available for chlorpromazine and hydrochlorothiazide

ArticleYear
The current status of lithium in psychiatry.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:6

    Topics: Acute Disease; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Female; Haloperidol; Humans; Hydrochlorothiazide; In Vitro Techniques; Lithium; Male; Mental Disorders; Placebos; Premenstrual Syndrome; Psychopharmacology; Recurrence; Thyroid Function Tests; Thyroid Gland; United States

1974

Other Studies

27 other study(ies) available for chlorpromazine and hydrochlorothiazide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Alteration of protein-binding during storage of human plasma preparations.
    Der Anaesthesist, 1977, Volume: 26, Issue:3

    Topics: Blood Preservation; Chlorpromazine; Freeze Drying; Freezing; Humans; Hydrochlorothiazide; Methicillin; Oxyphenbutazone; Propanidid; Protein Binding; Succinylcholine; Sulfadimethoxine; Temperature; Tetracycline; Thiopental; Time Factors

1977
Effects of colestipol hydrochloride on drug absorption in the rat II.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:9

    Topics: Animals; Cellulose; Chlorpromazine; Cholestyramine Resin; Clofibrate; Colestipol; Digitoxin; Digoxin; Hydrochlorothiazide; Intestinal Absorption; Male; Nicotinic Acids; Pharmaceutical Preparations; Phenobarbital; Polyamines; Rats; Tetracycline; Warfarin

1976
[Functional condition of the adrenal cortex in hypertensive disease during treatment].
    Vrachebnoe delo, 1972, Volume: 2

    Topics: Adrenal Glands; Benzimidazoles; Chlorpromazine; Humans; Hydrochlorothiazide; Hypertension; Parasympatholytics; Reserpine

1972
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:4

    Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors

1971
[Changes in the binding properties of plasma proteins in plasma stored under various conditions].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:1

    Topics: Blood Preservation; Blood Proteins; Chlorpromazine; Freezing; Hexobarbital; Hydrochlorothiazide; Methicillin; Oxyphenbutazone; Phenylacetates; Plasma; Protein Binding; Succinylcholine; Sulfadimethoxine; Tetracycline; Thiopental

1969
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm

1966
Photosensitization by drugs: photolysis of some chlorine-containing drugs.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:3

    Topics: Chemistry, Pharmaceutical; Chlorine; Chlorpromazine; Furosemide; Humans; Hydrochlorothiazide; Oxidation-Reduction; Pharmaceutical Preparations; Photochemistry; Photosensitivity Disorders; Prochlorperazine; Spectrophotometry, Ultraviolet

1980
Renal Na-reabsorption and O2-uptake in dogs during hypoxia and hydrochlorothiazide infusion.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1961, Volume: 106

    Topics: Animals; Chlorpromazine; Dogs; Humans; Hydrochlorothiazide; Hypoxia; Kidney; Sodium; Sodium, Dietary

1961
[Hydrochlorothiazide: a new complementary therapeutic agent in dermatology. (Preliminary report)].
    El Dia medico, 1959, Sep-07, Volume: 31

    Topics: Chlorpromazine; Dermatology; Hydrochlorothiazide

1959
LABORATORY METHODS FOR THE DETECTION OF ANTIHYPERTENSIVE DRUGS IN FLYING PERSONNEL.
    Aerospace medicine, 1963, Volume: 34

    Topics: Aerospace Medicine; Antihypertensive Agents; Antipsychotic Agents; Blood Chemical Analysis; Chlorothiazide; Chlorpromazine; Humans; Hydrochlorothiazide; Phenobarbital; Phenothiazines; Urine

1963
CLINICAL EXPERIENCE FROM THE TREATMENT OF MENI'ERE'S DISEASE.
    Acta oto-laryngologica. Supplementum, 1963, Volume: 192

    Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Chlorpromazine; Diet; Diet Therapy; Drainage; Ganglionic Blockers; Histamine; Histamine H1 Antagonists; Humans; Hydrochlorothiazide; Hypnotics and Sedatives; Labyrinthine Fluids; Meniere Disease; Neurosurgery; Parasympatholytics; Psychotherapy; Streptomycin; Surgical Procedures, Operative; Ultrasonic Therapy; Vasodilator Agents; Vestibular Nerve; Vitamins

1963