chlorpromazine and hydralazine

chlorpromazine has been researched along with hydralazine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199028 (66.67)18.7374
1990's3 (7.14)18.2507
2000's6 (14.29)29.6817
2010's5 (11.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Barr, JT; Jones, JP1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asboe-Hansen, G2
Schwarz, JA1
Maas, D; Schubothe, H1
Alarcon-Segovia, D; Fishbein, E1
Herbsman, H; Powers, JC; Shaftan, GW1
Hess, EV2
Burlingame, RW; Rubin, RL1
Cush, JJ; Goldings, EA1
Asboe-Hansen, G; Blumenkrantz, N1
Harpey, JP1
Medzihradsky, F; Nandhasri, PS1
Greengard, P; Quinn, GP; Reid, MB1
Bennett, EJ; Dalal, FY; el-Etr, AA; Salem, MR1
Tischler, E1
Catania, PN; King, JC1
Graf, H1
Nohira, T1
Jorring, K1
Davis, RA1
Anselmino, A1
Kalant, H; Lê, AD1
Harmon, CE; Portanova, JP1
Weinstein, A1
Jiang, X; Khursigara, G; Rubin, RL1
BRUNI, C; MEIER, R; TRIPOD, J1
HEPNER, L; REVERCHON, J; SAPIR, M; SELZER, S; STROUN, J1
LINDHOLM, T1
Akahoshi, T; Takemoto, T; Wada, T1

Reviews

8 review(s) available for chlorpromazine and hydralazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-related lupus.
    Current opinion in rheumatology, 1991, Volume: 3, Issue:5

    Topics: Antibodies, Antinuclear; Chlorpromazine; Drug Hypersensitivity; Eosinophilia-Myalgia Syndrome; Humans; Hydralazine; Interferon-alpha; Lupus Vulgaris; Models, Biological; Phenothiazines; Sulfhydryl Compounds

1991
Drug-induced lupus: clinical spectrum and pathogenesis.
    The American journal of the medical sciences, 1985, Volume: 290, Issue:1

    Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black People; Brain; Chlorpromazine; Female; Heart; Humans; Hydralazine; Isoniazid; Kidney; Liver; Lung; Lupus Erythematosus, Systemic; Male; Methyldopa; Muscles; Phenotype; Procainamide

1985
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis

1974
Effects of ethanol on thermoregulation.
    Pharmacology & therapeutics, 1983, Volume: 23, Issue:3

    Topics: Alcoholism; Animals; Behavior; Body Temperature Regulation; Chlorpromazine; Cold Temperature; Drug Interactions; Drug Tolerance; Electrophysiology; Ethanol; Hemodynamics; Hot Temperature; Humans; Hydralazine; Hypothalamus; Narcotics; Nerve Tissue Proteins; Neurotransmitter Agents; Prostaglandins; Respiration; Species Specificity; Temperature

1983
Drug-induced lupus: clinical and serological studies.
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:1

    Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cross Reactions; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Hydralazine; Hypertension; Isoniazid; Joint Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged; Pain; Pleural Effusion; Pleurisy; Procainamide; T-Lymphocytes

1982
Drug-induced systemic lupus erythematosus.
    Progress in clinical immunology, 1980, Volume: 4

    Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide

1980
[Fever induced by various drugs].
    Rinsho byori. The Japanese journal of clinical pathology, 2009, Volume: Suppl 143

    Topics: Amphetamine; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Body Temperature Regulation; Chlorpromazine; Contraindications; Dextromethorphan; Fever; Histamine Antagonists; Homeostasis; Humans; Hydralazine; Hypothalamus; Isoniazid; Lupus Erythematosus, Systemic; Sympathetic Nervous System

2009

Trials

2 trial(s) available for chlorpromazine and hydralazine

ArticleYear
Cerebral symptoms and blood pressure during parenteral administration of chlorpromazine, dihydralazine and diazoxide. Danish multicenter study on acute severe hypertension.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 678

    Topics: Blood Pressure; Brain Diseases; Brain Ischemia; Chlorpromazine; Clinical Trials as Topic; Diazoxide; Dihydralazine; Emergencies; Furosemide; Humans; Hydralazine; Hypertension; Hypotension; Paralysis; Risk

1983
Emergency treatment of severe hypertension evaluated in a randomized study. Effect of rest and furosemide and a randomized evaluation of chlorpromazine, dihydralazine and diazoxide. Danish Multicenter Study.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:6

    Topics: Adult; Aged; Chlorpromazine; Denmark; Diazoxide; Dihydralazine; Drug Administration Schedule; Female; Furosemide; Humans; Hydralazine; Hypertension; Male; Middle Aged; Posture; Prospective Studies; Random Allocation

1980

Other Studies

32 other study(ies) available for chlorpromazine and hydralazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Aldehyde Oxidase; Aminoacridines; Chromatography, Liquid; Enzyme Inhibitors; Humans; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction

2013
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1979
[Drug-induced disorders of lupus erythematosus type (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:96

    Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Procainamide; Rats

1977
[Drug-induced systemic lupus erythematosus (author's transl)].
    Immunitat und Infektion, 1977, Volume: 5, Issue:4

    Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine; Female; Humans; Hydralazine; Immune Tolerance; Lupus Erythematosus, Systemic; Methyldopa; Practolol; Procainamide

1977
Patterns of antinuclear antibodies and lupus-activating drugs.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Antibodies, Antinuclear; Anticonvulsants; Antigens; Chlorpromazine; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Nucleoproteins; Solubility; Tuberculosis, Pulmonary

1975
Evaluation of various hypotensive agents in the control of experimental hemorrhage.
    The Journal of surgical research, 1975, Volume: 18, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorpromazine; Diazoxide; Dogs; Drug Evaluation, Preclinical; Guanethidine; Hemorrhage; Hydralazine; Phenoxybenzamine; Protoveratrines; Tolazoline

1975
Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:2

    Topics: Autoantibodies; Chlorpromazine; Chromatin; DNA; Enzyme-Linked Immunosorbent Assay; Histones; Humans; Hydralazine; Immunoglobulin G; Immunoglobulin M; Lupus Vulgaris; Procainamide; Quinidine

1991
Connective-tissue effects of drugs causing lupoid syndrome.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chlorpromazine; Collagen; Depression, Chemical; Glucosamine; Hydralazine; Hydroxylation; Hydroxylysine; Hydroxyproline; Lupus Erythematosus, Systemic; Lysine; Mucoproteins; Procainamide; Proline; Tibia

1974
Effects of some analgesics and antidepressants on the (Na + + K + )-adenosine triphosphatase from cortices of brain and kidney.
    Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15

    Topics: Adenosine Triphosphatases; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cattle; Cerebral Cortex; Chlorpromazine; Cyclazocine; Desipramine; Dose-Response Relationship, Drug; Hydralazine; Imipramine; In Vitro Techniques; Kidney; Kidney Cortex; Pentazocine; Phenazocine; Phenelzine; Potassium; Sodium; Tranylcypromine

1972
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Anaesthesia for coarctation. A new classification for rational anaesthetic management.
    Anaesthesia, 1974, Volume: 29, Issue:6

    Topics: Anesthesia, General; Aortic Coarctation; Blood Pressure; Chlorpromazine; Collateral Circulation; Female; Humans; Hydralazine; Hypertension; Hypotension, Controlled; Infant; Male; Methods; Pain, Postoperative; Postoperative Complications; Reserpine; Vascular Resistance

1974
Intravenous chlormethiazole in the management of severe pre-eclampsia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1973, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Chlormethiazole; Chlorpromazine; Female; Fetal Death; Humans; Hydralazine; Hypothermia; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Parenteral; Maternal-Fetal Exchange; Medication Errors; Meperidine; Phlebitis; Pre-Eclampsia; Pregnancy; Promethazine

1973
The physico-chemical incompatibilities of selected cardiovascular and psychotherapeutic agents with sodium ethacrynate.
    American journal of hospital pharmacy, 1972, Volume: 29, Issue:2

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Chlorpromazine; Drug Combinations; Drug Compounding; Drug Incompatibility; Drug Stability; Ethacrynic Acid; Hydralazine; Hydrogen-Ion Concentration; Procainamide; Prochlorperazine; Promazine; Reserpine; Spectrum Analysis; Time Factors; Tolazoline; Tranquilizing Agents; Triflupromazine; Ultraviolet Rays

1972
[Therapy of pregnancy toxemias (EPH-gestosis, preeclampsia)].
    Deutsche medizinische Wochenschrift (1946), 1972, Apr-28, Volume: 97, Issue:17

    Topics: Blood Pressure Determination; Chlorpromazine; Dextrans; Diazepam; Diet Therapy; Edema; Female; Humans; Hydralazine; Meperidine; Phospholipids; Potassium Chloride; Pre-Eclampsia; Pregnancy; Promethazine; Reserpine

1972
[Indication for cesarean section: pregnancy toxemia].
    Sanfujinka no jissai. Practice of gynecology and obstetrics, 1972, Volume: 21, Issue:1

    Topics: Adult; Cesarean Section; Chlorpromazine; Female; Humans; Hydralazine; Pre-Eclampsia; Pregnancy; Reserpine

1972
[Cerebral anoxia during treatment of severe toxemias with hypotensive infusion].
    Ugeskrift for laeger, 1969, Nov-06, Volume: 131, Issue:45

    Topics: Adult; Chlorpromazine; Female; Humans; Hydralazine; Hypoxia, Brain; Pre-Eclampsia; Pregnancy

1969
Induction of fatal hypothermia in house-mice.
    The Annals of applied biology, 1968, Volume: 61, Issue:2

    Topics: Animals; Body Temperature; Chlorpromazine; Hydralazine; Hypothermia; Mecamylamine; Methyldopa; Mice; Nialamide; Phenoxybenzamine; Pyrimidines; Sulfonamides

1968
[Pathogenesis and therapy of essential arterial hypertension. Clinical case].
    Minerva medica, 1967, Apr-14, Volume: 58, Issue:30

    Topics: Adult; Aged; Analgesics; Blood Pressure Determination; Chlorothiazide; Chlorpromazine; Female; Guanethidine; Humans; Hydralazine; Hypertension; Male; Middle Aged; Reserpine

1967
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1982
Introduction to drug-related lupus.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acetylation; Acetyltransferases; Animals; Anticonvulsants; Autoimmune Diseases; Child; Chlorpromazine; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Phenothiazines; Procainamide; Sulfadiazine

1981
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.
    Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186

    Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydrogen Peroxide; Isoniazid; Lupus Erythematosus, Systemic; Mice; Neutrophil Activation; Neutrophils; Peroxidase; Procainamide; Propylthiouracil; Quinidine; Tumor Cells, Cultured

1994
[Pharmacodynamic differentiation of apresoline, serpasil and chlorpromazine by their effect on water retention in the rat].
    Archives internationales de pharmacodynamie et de therapie, 1955, Dec-01, Volume: 104, Issue:2

    Topics: Animals; Antihypertensive Agents; Chlorpromazine; Heart Failure; Hydralazine; Kidney; Rats; Reserpine; Secologanin Tryptamine Alkaloids; Sympatholytics; Water; Water-Electrolyte Balance

1955
[Psychosomatic action of chlorpromazine and reserpine].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Chlorpromazine; Humans; Hydralazine; Hypertension; Psychophysiologic Disorders; Reserpine

1956
[Anuria after or caused by obstetrical collapse treated with a nepresol-hibernalpethidine preparation].
    Svenska lakartidningen, 1958, May-30, Volume: 55, Issue:22

    Topics: Anuria; Chlorpromazine; Female; Humans; Hydralazine; Meperidine; Obstetric Labor Complications; Obstetrics; Pregnancy; Shock

1958