chlorpromazine and guanabenz

chlorpromazine has been researched along with guanabenz in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Faller, B; Wohnsland, F1
Caron, G; Ermondi, G1
Cohen, FE; Legname, G; May, BC; Prusiner, SB; Sherrill, J; Wallace, AC; Witkop, J; Zorn, JA1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Inoue, K; Kasai, H; Kobayashi, M; Kohno, S; Murata, T; Nagasaka, Y; Ohata, K; Sakamoto, H1
Bach, S; Blondel, M; Desban, N; Galons, H; Gug, F; Oumata, N; Tribouillard-Tanvier, D; Voisset, C1

Other Studies

9 other study(ies) available for chlorpromazine and guanabenz

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
    Journal of medicinal chemistry, 2007, Jan-11, Volume: 50, Issue:1

    Topics: Aminopyridines; Animals; Cell Line, Tumor; Combinatorial Chemistry Techniques; Membranes, Artificial; Mice; Models, Molecular; Nitriles; Permeability; PrPSc Proteins; Solubility; Structure-Activity Relationship

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Pharmacological studies of guanabenz: effects of the central nervous system].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:6

    Topics: Animals; Anticonvulsants; Avoidance Learning; Body Temperature; Brain; Chlorpromazine; Clonidine; Diazepam; Guanabenz; Guanidines; Male; Mice; Muscle Relaxants, Central; Psychomotor Performance; Rabbits; Rats; Rats, Inbred Strains; Sleep

1982
Synthesis of conjugates of 6-aminophenanthridine and guanabenz, two structurally unrelated prion inhibitors, for the determination of their cellular targets by affinity chromatography.
    Bioconjugate chemistry, 2010, Feb-17, Volume: 21, Issue:2

    Topics: Binding, Competitive; Chlorpromazine; Chromatography, Affinity; Guanabenz; Microspheres; Phenanthridines; Prions; Quinacrine; Ribosomes; RNA, Ribosomal; Sepharose

2010