chlorpromazine and fluorouracil

chlorpromazine has been researched along with fluorouracil in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (31.82)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (27.27)	29.6817
2010's	8 (36.36)	24.3611
2020's	1 (4.55)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Lam, YM; Martin, WM; Shiu, W; Tsang, V; Zacharia, A	1
Greene, PG; Seime, RJ	1
Brooks, M; Cadman, E; Tseng, A	1
Amblard, P; Bastrenta, F; Beani, JC; Gautron, R; Harrouch, L; Jardon, P; Reymond, JL	1
Bonnet, JD; Brindley, GV	1
Mikhaĭlova, LM; Suslov, NI; Syrkin, AB; Voronia, TA	1
Ikeda, K; Kawaguchi, Y; Masuda, H; Matsushima, E; Nagayama, S; Yoshisue, K	1
SCHELL, HW	1

Reviews

1 review(s) available for chlorpromazine and fluorouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for chlorpromazine and fluorouracil

Article	Year
A randomised cross-over trial comparing low-dose metoclopramide and chlorpromazine with high-dose metoclopramide in Chinese patients with advanced cancer receiving cisplatinum and 5-fluorouracil. Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Eating; Female; Fluorouracil; Hong Kong; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Random Allocation; Time Factors; Vomiting	1987

Article

Year

A randomised cross-over trial comparing low-dose metoclopramide and chlorpromazine with high-dose metoclopramide in Chinese patients with advanced cancer receiving cisplatinum and 5-fluorouracil.

Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Eating; Female; Fluorouracil; Hong Kong; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Random Allocation; Time Factors; Vomiting

1987

Other Studies

20 other study(ies) available for chlorpromazine and fluorouracil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Stimulus control of anticipatory nausea in cancer chemotherapy. Journal of behavior therapy and experimental psychiatry, 1987, Volume: 18, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorpromazine; Combined Modality Therapy; Conditioning, Classical; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nausea; Perceptual Masking; Taste	1987
Modulation of fluoropyrimidine metabolism by chlorpromazine. Biochemical and biophysical research communications, 1986, Jul-31, Volume: 138, Issue:2 Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Survival; Chlorpromazine; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Mice; Sarcoma, Experimental; Tritium; Uridine	1986
Screening for drug photosensitization activity by measuring the variations in oxygen consumption of Bacillus subtilis. Photo-dermatology, 1985, Volume: 2, Issue:2 Topics: Aspirin; Bacillus subtilis; Benzoyl Peroxide; Chlorpromazine; Erythromycin; Fluorouracil; Light; Methoxsalen; Oxygen Consumption; Patch Tests; Photosensitivity Disorders; Tretinoin	1985
Bronchial adenoma and the carcinoid syndrome. Annals of surgery, 1967, Volume: 165, Issue:5 Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Bronchial Neoplasms; Carcinoid Tumor; Chlorpromazine; Cyclophosphamide; Fluorouracil; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neoplasm Metastasis; Radiography	1967
[Pharmacological compatibility of the antineoplastic drugs ftorafur and 5-fluorouracil with the psychotropic drugs aminazine and phenazepam (an experimental study)]. Vestnik Akademii meditsinskikh nauk SSSR, 1984, Issue:5 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Drug Interactions; Fluorouracil; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasms, Experimental; Rats; Tegafur	1984
Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats. Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10 Topics: Administration, Oral; Allopurinol; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Carbon Radioisotopes; Chlorpromazine; Drug Combinations; Drugs, Chinese Herbal; Fluorouracil; Glycyrrhiza; Intestine, Small; Male; Microsomes, Liver; Oxonic Acid; Paeonia; Pyridines; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tegafur; Tissue Distribution; Triazines; Uracil; Xanthine Oxidase	2000
CURRENT STATUS OF 5-FLUOROURACIL THERAPY IN FAR-ADVANCED NEOPLASTIC DISEASE. Geriatrics, 1964, Volume: 19 Topics: Alopecia; Chlorpromazine; Diarrhea; Erythema; Fluorouracil; Leukopenia; Nausea; Neoplasms; Thrombocytopenia; Toxicology; Vomiting	1964