chlorpromazine and erythromycin

chlorpromazine has been researched along with erythromycin in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199016 (38.10)18.7374
1990's0 (0.00)18.2507
2000's10 (23.81)29.6817
2010's16 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Abraham, MH; Acree, WE; Ibrahim, A1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barreca, ML; Cannalire, R; Cecchetti, V; Couto, I; Felicetti, T; Machado, D; Manfroni, G; Massari, S; Sabatini, S; Santos Costa, S; Tabarrini, O; Viveiros, M1
Drew, R; Piestly, BG1
Hiller, FC; Olsen, KM1
Amblard, P; Bastrenta, F; Beani, JC; Gautron, R; Harrouch, L; Jardon, P; Reymond, JL1
Kendler, J; Libber, S; Lukacs, L; Zimmerman, HJ1
Bornschein, M; Florstedt, H; Richter, B; Voigt, R1
Edwards, WM1
Bianchine, JR; Dujovne, CA; Lasagna, L; Lavelle, G; Weiss, P1
Ishida, K; Suwa, K; Taguchi, I; Uehara, K; Ushio, K1
Linares Rodríguez, A; Recarte Alvarez, J; Rodrigo Sáez, L; Valerdiz Casasola, S1
Hewlett, EL; Myers, GA; Pearson, RD1
Abernathy, CO; Lukacs, L; Zimmerman, HJ1
TITOVA, AI1
LEAU, O1
NASSER, WK1
ARIAS, S; NEGRETE, D; RUIZSANCHEZ, A; RUIZSANCHEZ, F1
CORMIA, FE1
Matsudaira, H; Searashi, Y; Takagi, I1

Reviews

3 review(s) available for chlorpromazine and erythromycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Hepatitis caused by drugs. 5].
    Revista espanola de las enfermedades del aparato digestivo, 1982, Volume: 62, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Deoxyepinephrine; Erythromycin; Gold; Humans; Hypoglycemic Agents; Oxacillin; Oxyphenisatin Acetate; Perhexiline; Phenylbutazone; Prognosis; Propylthiouracil

1982
[Drug-induced cholestasis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antineoplastic Agents; Antipsychotic Agents; Chlorpromazine; Cholestasis; Drugs, Chinese Herbal; Erythromycin; Humans; Immunosuppressive Agents; Penicillins; Sulfamethoxazole; Testosterone Congeners; Trimethoprim

2007

Other Studies

39 other study(ies) available for chlorpromazine and erythromycin

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Anti-Bacterial Agents; Drug Design; Genistein; Mycobacterium avium; Quinolones

2017
Effect of chlorpromazine and erythromycin on bile salt-induced cholestasis in the rat.
    Pharmacology, 1979, Volume: 18, Issue:4

    Topics: Alanine Transaminase; Animals; Bile; Chlorpromazine; Cholestasis; Drug Interactions; Erythromycin; Erythromycin Estolate; Humans; Male; Nucleotidases; Rats; Taurochenodeoxycholic Acid; Taurolithocholic Acid

1979
Management of tetanus.
    Clinical pharmacy, 1987, Volume: 6, Issue:7

    Topics: Aged; Aged, 80 and over; Chlorpromazine; Clostridium tetani; Darkness; Diazepam; Erythromycin; Female; Humans; Intensive Care Units; Middle Aged; Morphine; Ranitidine; Tetanus; Tetanus Toxoid

1987
Screening for drug photosensitization activity by measuring the variations in oxygen consumption of Bacillus subtilis.
    Photo-dermatology, 1985, Volume: 2, Issue:2

    Topics: Aspirin; Bacillus subtilis; Benzoyl Peroxide; Chlorpromazine; Erythromycin; Fluorouracil; Light; Methoxsalen; Oxygen Consumption; Patch Tests; Photosensitivity Disorders; Tretinoin

1985
Hepatocyte suspensions as a model for demonstration of drug hepatotoxicity.
    Biochemical pharmacology, 1974, Volume: 23, Issue:15

    Topics: Animals; Aspartate Aminotransferases; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chlorpromazine; Erythromycin; In Vitro Techniques; Liver; Models, Biological; Osmolar Concentration; Rats

1974
[Effect of surface-active substances on artificial (hydrophilic) membranes].
    Die Pharmazie, 1972, Volume: 27, Issue:9

    Topics: Biopharmaceutics; Cellulose; Chlorpromazine; Dialysis; Erythromycin; Membranes, Artificial; Methods; Nitrates; Rifamycins; Sodium; Sodium Dodecyl Sulfate; Surface-Active Agents

1972
[Tetanus neonatorum].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:6

    Topics: Amobarbital; Anti-Bacterial Agents; Chloral Hydrate; Chlorpromazine; Erythromycin; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Penicillins; Prognosis; Streptomycin; Tetanus; Tetanus Antitoxin

1970
Toxicity of hepatotoxic drugs on mouse liver tissue culture.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:1

    Topics: Animals; Chlorpromazine; Culture Techniques; Erythromycin; Glucuronidase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Mice; Promazine

1970
[6 recent cases of toxic hepatitis].
    Naika. Internal medicine, 1966, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Chlorpromazine; Erythromycin; Female; Humans; Male; Middle Aged; Novobiocin; Phosphorus; Porphyrias

1966
Susceptibility of Bordetella species to growth inhibition and killing by chlorpromazine.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Bordetella; Chlorpromazine; Erythromycin; Microbial Sensitivity Tests

1983
Cytotoxic effects of erythromycin estolate and chlorpromazine on hepatocytes isolated from rats of varying ages: a brief note.
    Mechanisms of ageing and development, 1980, Volume: 12, Issue:1

    Topics: Aging; Animals; Aspartate Aminotransferases; Cell Extracts; Chlorpromazine; Erythromycin; Erythromycin Estolate; In Vitro Techniques; Liver; Male; Rats

1980
[APROPOS OF PREVENTION AND TREATMENT OF PNEUMONIA IN YOUNG CHILDREN].
    Pediatriia, 1963, Volume: 42

    Topics: Anti-Bacterial Agents; Child; Chlorpromazine; Erythromycin; gamma-Globulins; Infant; Infant, Newborn; Oxytetracycline; Penicillins; Pneumococcal Infections; Pneumonia; Pneumonia, Viral; Staphylococcal Infections; Streptomycin; Tetracycline

1963
[RELATION BETWEEN BLOOD CONCENTRATION AND THERAPEUTIC ACTION].
    La Presse medicale, 1963, Oct-12, Volume: 71

    Topics: Amidines; Anti-Bacterial Agents; Blood Chemical Analysis; Chlorpromazine; Chlorprothixene; Drug Therapy; Erythromycin; Imipramine; Oleandomycin; Penicillins; Promazine; Promethazine; Quinolines; Spiramycin; Stilbamidines; Suramin; Tetracycline; Tranquilizing Agents

1963
CLINICAL TETANUS: TREATMENT OF TEN CASES.
    The Journal of the Indiana State Medical Association, 1964, Volume: 57

    Topics: Chlorpromazine; Debridement; Desensitization, Immunologic; Erythromycin; Humans; Injections; Injections, Intramuscular; Mephenesin; Meprobamate; Nursing; Parenteral Nutrition; Penicillins; Secobarbital; Tetanus; Tetanus Antitoxin; Tetanus Toxoid; Tracheotomy

1964
[BENZODIAZEPINE AS A COADJUVANT IN THE TREATMENT OF TETANUS].
    Medicina, 1964, Aug-25, Volume: 44

    Topics: Anti-Bacterial Agents; Benzodiazepines; Chlorpromazine; Diazepam; Drug Therapy; Erythromycin; Humans; Meprobamate; Penicillins; Promethazine; Protein Synthesis Inhibitors; Tetanus; Tetanus Toxoid; Tetracycline

1964
POTENTIATION OF HYPERPIGMENTATION FROM X-RADIATION. EFFECTS OF DEMETHYLCHLORTETRACYCLINE THERAPY.
    Archives of dermatology, 1964, Volume: 90

    Topics: Acne Vulgaris; Chlorpromazine; Demeclocycline; Drug Therapy; Erythromycin; Facial Dermatoses; Humans; Hyperpigmentation; Pigmentation Disorders; Radiation Effects; Radiotherapy; X-Rays

1964