chlorpromazine and droperidol

chlorpromazine has been researched along with droperidol in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199024 (60.00)18.7374
1990's1 (2.50)18.2507
2000's7 (17.50)29.6817
2010's8 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Echter, E; Levante, A; Raggueneau, JL; Trawale, JM1
Fujita, M; Fukuuchi, A; Furuya, Y; Nagara, M; Ooe, Y; Tanaka, S1
Hiller, HH; Merkenschlager, M1
Kawasaki, T; Maruyama, S1
Gillis, MF; Ragan, HA1
Andics, A; Gogolák, G; Huck, S; Stumpf, C1
Dubois-Primo, J2
Grankvist, K; Henriksson, R1
Kehoe, R; Young, A1
Olson, LG; Saunders, NA1
Kondratovich, MA; Meleshchenko, AA1
Ilkiw, JE; Rose, RJ; Turner, DM; Warren, JM1
Bárdosi, Z; Benyó, I; Csengödy, J; Gaál, J; Karika, G1
Kania, BF; Teuchmann, JK1
Michalek, H1
Poshivalov, VP1
Meleshchenko, AA1
Hawker, RE; Krovetz, LJ1
Buckman, R; Starke, I; Stuart-Harris, R; Wiltshaw, E1
Horsten, GP; Huygen, PL; Verhagen, WI1
Batrak, GN; Degtiar, VY; Hawryluk, BR; Luik, AI; Mogilevich, SE; Naydyenova, IY; Prokopenko, RA1
JANSSEN, PA; NIEMEGEERS, CJ; SCHELLEKENS, KH; VAN NUETEN, JM; VERBRUGGEN, FJ1
DIETRICH, EV; KATZ, R; YELNOSKY, J1
Prosekina, EIu; Stepanova, LG; Tomova, TA1
Harvey, R; Kekulawala, S; Kent, M; Mostafa, S; Tucker, MG1

Reviews

3 review(s) available for chlorpromazine and droperidol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Elimination of pain in laboratory animals].
    Berliner und Munchener tierarztliche Wochenschrift, 1975, Aug-01, Volume: 88, Issue:15

    Topics: Acepromazine; Anesthesia, General; Anesthetics; Animals; Animals, Laboratory; Azaperone; Chloroform; Chlorpromazine; Cricetinae; Dose-Response Relationship, Drug; Droperidol; Ethers; Gerbillinae; Guinea Pigs; Halothane; Hexobarbital; Imidazoles; Ketamine; Lethal Dose 50; Methoxyflurane; Mice; Pentobarbital; Rabbits; Rats; Swine; Urethane

1975
Restraint, venipuncture, endotracheal intubation, and anesthesia of miniature swine.
    Laboratory animal science, 1975, Volume: 25, Issue:4

    Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, Inhalation; Animals; Animals, Laboratory; Bloodletting; Chlordiazepoxide; Chlorpromazine; Diazepam; Droperidol; Electronarcosis; Fentanyl; Immobilization; Intubation, Intratracheal; Ketamine; Meperidine; Pentobarbital; Phencyclidine; Preanesthetic Medication; Punctures; Swine; Swine Diseases; Thiopental; Vena Cava, Superior

1975

Trials

1 trial(s) available for chlorpromazine and droperidol

ArticleYear
Chlorpromazine, placebo and droperidol in the treatment of nausea and vomiting associated with cisplatin therapy.
    Postgraduate medical journal, 1983, Volume: 59, Issue:694

    Topics: Chlorpromazine; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Droperidol; Female; Humans; Nausea; Vomiting

1983

Other Studies

36 other study(ies) available for chlorpromazine and droperidol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Neuroleptics and continuous measurement of intracranial pressure].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Child; Chlorpromazine; Chlorprothixene; Craniocerebral Trauma; Droperidol; Female; Humans; Intracranial Pressure; Male; Methods; Middle Aged; Time Factors; Tranquilizing Agents

1976
[Effects of vasoactive drugs on renal circulation. II. alpha-Adrenergic blockers (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1979, Volume: 28, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Chlorpromazine; Dogs; Droperidol; Hemodynamics; Humans; Kidney; Phenoxybenzamine; Phentolamine

1979
Further electrophysiological evidence for the GABA-like effect of droperidol in the Purkinje cells of the cat cerebellum.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:6

    Topics: Aminobutyrates; Animals; Cats; Cerebellum; Chlorpromazine; Droperidol; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Imidazoles; In Vitro Techniques; Purkinje Cells

1976
[Action of central depressants on the nitrous oxide anesthesia (author's transl)].
    Der Anaesthesist, 1975, Volume: 24, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Chlorpromazine; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; Drug Synergism; Flunitrazepam; Male; Mice; Morphine; Nitrazepam; Nitrous Oxide; Pentobarbital; Tranquilizing Agents

1975
Comparison between fentanyl and morphine for use in analgesic anesthesia during open heart surgery.
    Acta anaesthesiologica Belgica, 1975, Volume: 26, Issue:1

    Topics: Adult; Aged; Anesthesia, General; Blood Pressure; Cardiac Surgical Procedures; Chlorpromazine; Droperidol; Extracorporeal Circulation; Female; Fentanyl; Heart Rate; Humans; Male; Middle Aged; Morphine; Postoperative Care

1975
Epirubicin cytotoxicity but not oxygen radical formation is enhanced by four different antiemetics.
    Medical oncology and tumor pharmacotherapy, 1989, Volume: 6, Issue:2

    Topics: Animals; Antiemetics; Antipsychotic Agents; Cell Line; Cell Survival; Chlorpromazine; Cricetinae; Droperidol; Drug Synergism; Epirubicin; Fibroblasts; Free Radicals; Metoclopramide; Oxygen Consumption; Phenothiazines

1989
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Droperidol; Drug Therapy, Combination; Female; Flupenthixol; Fluphenazine; Humans; Long-Term Care; Male; Middle Aged; Paranoid Disorders; Psychotic Disorders

1989
Ventilatory stimulation by dopamine-receptor antagonists in the mouse.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Carotid Body; Chlorpromazine; Dopamine Antagonists; Droperidol; Haloperidol; Male; Mice; Mice, Inbred Strains; Phentolamine; Prochlorperazine; Receptors, Dopamine; Respiration; Stimulation, Chemical

1985
[Effect of aminazin and droperidol on cerebral circulation and its regulation].
    Kardiologiia, 1973, Volume: 13, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebrovascular Circulation; Chlorpromazine; Dogs; Droperidol; Vasodilator Agents

1973
Respiratory and cardiovascular effects of five drugs used as sedatives in the dog.
    Australian veterinary journal, 1974, Volume: 50, Issue:6

    Topics: Acepromazine; Allyl Compounds; Animals; Blood; Blood Pressure; Carbon Dioxide; Chlorpromazine; Diethylamines; Dogs; Droperidol; Fentanyl; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Meperidine; Oxygen; Partial Pressure; Respiration; Thiophenes

1974
[Changes in blood pressure conditioned by interoceptive reflexes during narcosis (author's transl)].
    Der Anaesthesist, 1974, Volume: 23, Issue:7

    Topics: Anesthesia, Endotracheal; Anesthetics; Animals; Blood Pressure; Cerebral Cortex; Chloralose; Chlorpromazine; Dogs; Droperidol; Hypotension; Neuroleptanalgesia; Reflex

1974
[Studies on the peripheral action of chlorpromazine, reserpine, dehydrobenzperidol, azacyclonol, hydroxyzine, and xylazine].
    Polskie archiwum weterynaryjne, 1972, Volume: 15, Issue:4

    Topics: Aniline Compounds; Animals; Chlorpromazine; Droperidol; Hydroxyzine; Muscle Contraction; Muscles; Piperidines; Rats; Reserpine; Thiazines; Tibia; Tranquilizing Agents; Xylenes

1972
Inhibition of cholinesterase and acetylcholinesterase in vitro by butyrophenone neuroleptics.
    Biochemical pharmacology, 1973, May-01, Volume: 22, Issue:9

    Topics: Animals; Benperidol; Butyrophenones; Chlorpromazine; Cholinesterase Inhibitors; Droperidol; Eels; Electric Organ; Haloperidol; Horses; Imipramine; In Vitro Techniques; Kinetics; Spectrophotometry; Tranquilizing Agents

1973
[Study of the psychotropic effect of analgesics and neuroleptics based on a model of exploratory behavior modified by pain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 76, Issue:8

    Topics: Analgesics; Animals; Behavior, Animal; Chlorpromazine; Droperidol; Fentanyl; Male; Mice; Morphine; Tranquilizing Agents

1973
[Effect of aminazine and droperidol on blood flow resistance in the vessels of the kidney and their regulatory reactions].
    Farmakologiia i toksikologiia, 1973, Volume: 36, Issue:5

    Topics: Animals; Chlorpromazine; Dogs; Droperidol; Kidney; Reflex; Regional Blood Flow; Vascular Resistance

1973
Depression of cardiac output by sedation in congenital semilunar valve stenosis.
    American heart journal, 1974, Volume: 87, Issue:1

    Topics: Aortic Valve Stenosis; Blood Pressure; Cardiac Output; Child; Chlorpromazine; Droperidol; Fentanyl; Heart Valve Diseases; Humans; Hypnotics and Sedatives; Meperidine; Promethazine; Pulmonary Valve Stenosis

1974
Flash induced nystagmus (FIN) in the rabbit: input-output relations.
    The International journal of neuroscience, 1984, Volume: 24, Issue:2

    Topics: Animals; Chlorpromazine; Droperidol; Hair Color; Nystagmus, Physiologic; Photic Stimulation; Rabbits

1984
Anesthesia with flunitrazepam and fentanyl supplemented with droperidol or chlorpromazine (Largactil) in coronary surgery.
    Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:2

    Topics: Anesthesia; Cardiac Surgical Procedures; Chlorpromazine; Coronary Artery Bypass; Droperidol; Female; Fentanyl; Flunitrazepam; Heart Rate; Humans; Hypertension; Male; Middle Aged; Time Factors

1981
Effects of haloperidol and chlorpromazine on smooth muscle contractility, platelet aggregation and neuronal calcium current.
    General physiology and biophysics, 1995, Volume: 14, Issue:4

    Topics: Animals; Antipsychotic Agents; Butyrophenones; Calcium Channel Blockers; Calcium Channels; Calmodulin; Chlorpromazine; Droperidol; Electric Stimulation; Guinea Pigs; Haloperidol; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Neurons; Phenothiazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prazosin; Rats; Rats, Wistar; Snails; Sulpiride; Thrombin; Ureter; Verapamil

1995
The pharmacology of dehydrobenzperidol, a new potent and short acting neuroleptic agent chemically related to Haloperidol.
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Antipsychotic Agents; Chlorpromazine; Droperidol; Haloperidol; Humans; Tranquilizing Agents

1963
A STUDY OF SOME OF THE PHARMACOLOGIC ACTIONS OF DROPERIDOL.
    Toxicology and applied pharmacology, 1964, Volume: 5

    Topics: Benzimidazoles; Blood Pressure; Cardiovascular System; Chlorpromazine; Dogs; Droperidol; Heart; Hypnotics and Sedatives; Mice; Pharmacology; Research; Sympatholytics; Tachycardia; Toxicology; Tranquilizing Agents; Ventricular Fibrillation

1964
[Treatment of surgical stress response by neuroleptics, leu-enkephalin, glycyl-proline dipeptide, and electroanesthesia in experimental animals].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:8

    Topics: Acepromazine; Animals; Antipsychotic Agents; Chlorpromazine; Dipeptides; Dogs; Droperidol; Enkephalin, Leucine; Gastric Emptying; Gastric Mucosa; Laparoscopy; Male; Neurotransmitter Agents; Pain; Pain Measurement; Rats; Rats, Wistar; Stomach; Stress, Physiological; Swine; Transcutaneous Electric Nerve Stimulation

2014
Polysubstance-induced relapse of schizoaffective disorder refractory to high-dose antipsychotic medications: a case report.
    Journal of medical case reports, 2016, Sep-06, Volume: 10, Issue:1

    Topics: Adult; Amphetamine-Related Disorders; Antipsychotic Agents; Chlorpromazine; Clopenthixol; Droperidol; Drug Administration Schedule; Emergency Medical Services; Humans; Hypnotics and Sedatives; Lorazepam; Male; Marijuana Abuse; Methamphetamine; Psychotic Disorders; Time Factors; Treatment Outcome; Violence

2016