chlorpromazine and doxepin

chlorpromazine has been researched along with doxepin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199019 (59.38)18.7374
1990's1 (3.13)18.2507
2000's7 (21.88)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Chiang, GH; Unger, SH1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dhawan, NS; Izadmehr, S; Kastrinsky, DB; Narla, G; Ohlmeyer, M; Sangodkar, J; Zaware, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ketai, R1
Gescher, A; Li Wan Po, A1
Baker, GA; Blumenstein, J; Santalo, R1
Joost, HG1
Edwards, JL; Poe, TE; Taylor, RB1
Warneke, L1
Leander, JD; McMillan, DE1
Frankel, BL; Prunier, PG1
Tuomisto, J1
Kaneto, H; Koida, M; Miyagawa, H; Tsuchie, F1
Lee, RE1
Lassen, JB1
Mattila, MJ; Saarnivaara, L1
Chung, C; Cook, P; Pendleton, RG; Risley, E; Williams, M1
Cassone, MC; Fundarò, A; Molinengo, L1
Falterman, CG; Richardson, CJ1
Huang, Z; Liu, W; Wu, H; Zhuo, X1
Da, SL; Feng, YQ; He, HB; Hu, ZX; Qu, L1

Reviews

2 review(s) available for chlorpromazine and doxepin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

30 other study(ies) available for chlorpromazine and doxepin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Reengineered tricyclic anti-cancer agents.
    Bioorganic & medicinal chemistry, 2015, Oct-01, Volume: 23, Issue:19

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compounds, 3-Ring; Humans; Mice; Neoplasms; Phenothiazines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous; Vesicular Monoamine Transport Proteins

2015
High-dosage and versatile drug therapy with treatment-resistant psychotic patients.
    Hospital & community psychiatry, 1976, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Doxepin; Female; Hospitals, Psychiatric; Humans; Male; Perphenazine; Psychotic Disorders; Schizophrenia; Thiothixene; Trifluoperazine

1976
Correlation of physicochemical properties with absorption and metabolism of some tricyclic drugs.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:6

    Topics: Absorption; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Doxepin; Imipramine; In Vitro Techniques; Male; Methylation; Phenothiazines; Promazine; Promethazine; Rats; Surface Tension

1978
Effect of psychotropic agents upon the blastogenic response of human t-lymphocytes.
    Biological psychiatry, 1977, Volume: 12, Issue:2

    Topics: Chlorpromazine; Depression, Chemical; DNA; Dopamine; Doxepin; Drug Synergism; Fluphenazine; Haloperidol; Humans; In Vitro Techniques; Lymphocyte Activation; Osmolar Concentration; Prochlorperazine; Proteins; RNA; T-Lymphocytes; Thiothixene; Thymidine; Tranquilizing Agents; Trifluoperazine; Uridine

1977
Inhibition of insulin secretion from the perfused pancreas of the rat by pizotifen.
    British journal of pharmacology, 1979, Volume: 67, Issue:2

    Topics: Animals; Chlorpromazine; Cyproheptadine; Doxepin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pizotyline; Rats; Thiophenes

1979
Hypertensive crisis possibly due to drug interaction.
    Postgraduate medicine, 1979, Volume: 66, Issue:5

    Topics: Blood Pressure; Chlorpromazine; Depression; Doxepin; Drug Interactions; Guanethidine; Humans; Hypertension; Male; Middle Aged

1979
A case of manic-depressive illness in childhood.
    Canadian Psychiatric Association journal, 1975, Volume: 20, Issue:3

    Topics: Adolescent; Age Factors; Alberta; Bipolar Disorder; Child; Chlorpromazine; Doxepin; Electroconvulsive Therapy; Electroencephalography; Haloperidol; Humans; Lithium; Male; Psychological Tests

1975
Drugs and punished responding. V. Effects of drugs on responding suppressed by response-dependent and response-independent electric shock.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 213, Issue:1

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Columbidae; Conditioning, Operant; Dextroamphetamine; Doxepin; Ethanol; Male; Morphine; Pentazocine; Pentobarbital; Punishment; Reinforcement Schedule

1975
Atypical fatal hyperpyrexia: a case report.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:5

    Topics: Adult; Chlorpromazine; Doxepin; Female; Fever; Humans

1986
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine

1974
[Screening procedure for barbital type physical dependence liability of psychotropic drugs in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Amitriptyline; Animals; Barbiturates; Behavior, Animal; Benzazepines; Benzodiazepinones; Body Weight; Carboxylic Acids; Chlordiazepoxide; Chlorpromazine; Diazepam; Doxepin; Dronabinol; Humans; Imines; Isoquinolines; Male; Mice; Morphine; Nitrazepam; Oxazoles; Substance Withdrawal Syndrome; Substance-Related Disorders; Tranquilizing Agents

1973
The influence of psychotropic drugs on prostaglandin biosynthesis.
    Prostaglandins, 1974, Jan-10, Volume: 5, Issue:1

    Topics: Animals; Antidepressive Agents; Aspirin; Carbon Radioisotopes; Cell-Free System; Chlorpromazine; Chromatography, Thin Layer; Depression, Chemical; Desipramine; Doxepin; Guinea Pigs; Indomethacin; Lung; Methods; Pargyline; Phenelzine; Promazine; Prostaglandins; Tranylcypromine

1974
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction.
    Psychopharmacologia, 1974, Jan-14, Volume: 34, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors

1974
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
    Psychopharmacologia, 1974, Feb-27, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors

1974
Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Brain; Chlorpromazine; Desipramine; Doxepin; Gastric Acid; Male; Pirenzepine; Rats; Rats, Inbred Strains

1984
Action of antidepressants, stimulants and depressants in the transition from a fixed ratio to a fixed interval schedule of reinforcement.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:1

    Topics: Amitriptyline; Amphetamine; Animals; Caffeine; Chlorpromazine; Conditioning, Operant; Diazepam; Doxepin; Imipramine; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Reinforcement Schedule

1983
Small left colon syndrome associated with maternal ingestion of psychotropic drugs.
    The Journal of pediatrics, 1980, Volume: 97, Issue:2

    Topics: Benztropine; Biperiden; Chlorpromazine; Colonic Diseases, Functional; Doxepin; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Male; Pregnancy; Pregnancy Complications; Psychotropic Drugs; Schizophrenia; Thiothixene

1980
[Determination of basic drugs in blood by RP-HPLC].
    Fa yi xue za zhi, 1997, Volume: 13, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Chromatography, High Pressure Liquid; Doxepin; Humans; Perphenazine

1997
High-performance liquid chromatography of some basic drugs on a n-octadecylphosphonic acid modified magnesia-zirconia stationary phase.
    Journal of separation science, 2005, Volume: 28, Issue:13

    Topics: Chlorpromazine; Doxepin; Drug Stability; Hydrogen-Ion Concentration; Indicators and Reagents; Magnesium Oxide; Organic Chemicals; Organophosphonates; Pharmaceutical Preparations; Verapamil; Zirconium

2005