chlorpromazine and domperidone

chlorpromazine has been researched along with domperidone in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199012 (30.00)18.7374
1990's5 (12.50)18.2507
2000's14 (35.00)29.6817
2010's9 (22.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P1
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P1
Andrews, PR; Craik, DJ; Martin, JL1
Emms, F; Freedman, SB; Knowles, MR; Marwood, R; McAllister, G; Patel, S; Seabrook, GR1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Topliss, JG; Yoshida, F1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Caron, G; Ermondi, G; Visentin, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Sen, S; Sinha, N1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Barr, JT; Jones, JP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Evans, AM; Green, KL2
Convents, A; De Backer, JP; De Keyser, J; Ebinger, G; Vauquelin, G1
Hikasa, Y; Ogasawara, S; Takase, K1
Blanchard, JC; Boireau, A; Carruette, AM; Chambry, J; Dubedat, P; Farges, G; Zundel, JL1
MacVicar, BA; Pittman, QJ1
Sondervan-Frank, BS1
Bodini, OA; Capdopon, E; Cesolari, JA; Laudanno, OM; San Miguel, P1
Brizzee, KR; Miller, JD1
Fujita, J; Funaki, U; Futami, H; Saijo, N; Sasaki, Y; Sawamura, N; Shimizu, E; Shinkai, T; Takahashi, S; Yokoyama, S1
Randall, PK; Yurek, DM1
Besser, GM; Delitala, G; Grossman, A; Stubbs, WA; Yeo, T1
Araki, Y; Seita, M; Tamura, K1
Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S1
Allain-Veyrac, G; Berezowski, V; Cecchelli, R; Jolliet, P; Nion, S; Tilloy-Fenart, L; Vanuxeem, D1
Azariah, F; Bettiol, S; Lavender, VT; Smith, LA; Stoner, NS1
Badaoui, M; Dickson, CJ; Hornak, V; Kells, A; Molteni, C; Rosta, E1

Reviews

2 review(s) available for chlorpromazine and domperidone

ArticleYear
[The control of chemotherapy-induced nausea and vomiting].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:7

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Humans; Killer Cells, Natural; Metoclopramide; Nausea; Neoplasms; Vomiting

1985
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
    The Cochrane database of systematic reviews, 2015, Nov-12, Issue:11

    Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Euphoria; Humans; Metoclopramide; Nausea; Neoplasms; Prochlorperazine; Randomized Controlled Trials as Topic; Vomiting

2015

Other Studies

38 other study(ies) available for chlorpromazine and domperidone

ArticleYear
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection

1992
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
    Nature, 1990, Sep-13, Volume: 347, Issue:6289

    Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution

1990
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Expression and pharmacological characterization of the human D3 dopamine receptor.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Animals; Binding, Competitive; Cells, Cultured; CHO Cells; Cricetinae; Dopamine; Dopamine Antagonists; GTP-Binding Proteins; Guanine Nucleotides; Humans; Potassium Channels; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Second Messenger Systems; Sulpiride

1994
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Aldehyde Oxidase; Aminoacridines; Chromatography, Liquid; Enzyme Inhibitors; Humans; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The action of dopamine receptor antagonists on the secretory response of the cockroach salivary gland in vitro.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1990, Volume: 97, Issue:2

    Topics: Animals; Benzazepines; Binding, Competitive; Chlorpromazine; Cockroaches; Domperidone; Dopamine; Dopamine Antagonists; Haloperidol; Metoclopramide; Salivary Glands; Sulpiride

1990
Characterization of the dopamine receptor mediating the hyperpolarization of cockroach salivary gland acinar cells in vitro.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Benzazepines; Chlorpromazine; Cockroaches; Domperidone; Electric Stimulation; Haloperidol; In Vitro Techniques; Kinetics; Metoclopramide; Receptors, Dopamine; Salivary Glands; Sulpiride

1990
D2 dopamine receptors in calf globus pallidus: agonist high- and low-affinity sites not regulated by guanine nucleotide.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Animals; Butaclamol; Cattle; Chlorpromazine; Corpus Striatum; Domperidone; Dopamine; Globus Pallidus; Guanosine Triphosphate; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone

1985
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
    American journal of veterinary research, 1989, Volume: 50, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Chlorpromazine; Diphenhydramine; Domperidone; Female; Hydroxydopamines; Male; Naloxone; Oxidopamine; Propranolol; Random Allocation; Receptors, Adrenergic, alpha; Thiazines; Vomiting; Xylazine

1989
Enhancing effect of dopamine blockers on evoked acetylcholine release in rat striatal slices: a classical D-2 antagonist response?
    European journal of pharmacology, 1986, Aug-22, Volume: 128, Issue:1-2

    Topics: Acetylcholine; Animals; Benzazepines; Chlorpromazine; Corpus Striatum; Domperidone; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Male; Phenothiazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Sulpiride

1986
Novel synaptic responses mediated by dopamine and gamma-aminobutyric acid in neuroendocrine cells of the intermediate pituitary.
    Neuroscience letters, 1986, Feb-14, Volume: 64, Issue:1

    Topics: Animals; Bicuculline; Chlorpromazine; Domperidone; Dopamine; Electric Conductivity; gamma-Aminobutyric Acid; Membrane Potentials; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission

1986
[Promoting lactation with the aid of drugs].
    Nederlands tijdschrift voor geneeskunde, 1987, Jun-27, Volume: 131, Issue:26

    Topics: Chlorpromazine; Cimetidine; Domperidone; Female; Humans; Lactation; Medroxyprogesterone; Metoclopramide; Oxytocin; Pregnancy; Prolactin; Sulpiride; Thyrotropin-Releasing Hormone

1987
[Cytoprotection of gastric mucosa induced by tripotassium-dicitrato bismuthate against ethanol stress. Dependent mechanisms of sulfhydryl, dopaminergic and endogenous prostaglandin].
    Acta gastroenterologica Latinoamericana, 1986, Volume: 16, Issue:1

    Topics: Acetazolamide; Animals; Chlorpromazine; Domperidone; Ethanol; Female; Gastric Mucosa; Indomethacin; Male; Mercuric Chloride; Necrosis; Organometallic Compounds; Rats; Rats, Inbred Strains

1986
The anti-emetic properties of 1-sulpiride in a ground-based model of space motion sickness.
    Life sciences, 1987, Oct-12, Volume: 41, Issue:15

    Topics: Animals; Antiemetics; Chlorpromazine; Disease Models, Animal; Domperidone; Female; Male; Motion Sickness; Prochlorperazine; Saimiri; Sulpiride; Thiethylperazine; Triflupromazine

1987
Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice.
    Life sciences, 1985, Nov-04, Volume: 37, Issue:18

    Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Domperidone; Drug Interactions; Haloperidol; Injections, Intraventricular; Mice; Spiperone; Stereotyped Behavior; Sulpiride

1985
Chlorpromazine, haloperidol, metoclopramide and domperidone release prolactin through dopamine antagonism at low concentrations but paradoxically inhibit prolactin release at high concentrations.
    British journal of pharmacology, 1980, Volume: 71, Issue:2

    Topics: Animals; Antipsychotic Agents; Benzimidazoles; Cells, Cultured; Chlorpromazine; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Metoclopramide; Piperidines; Pituitary Gland, Anterior; Prolactin; Rats

1980
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Vomiting

1983
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
    BMC neuroscience, 2006, Mar-30, Volume: 7

    Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride

2006
Evidence of lowest brain penetration of an antiemetic drug, metopimazine, compared to domperidone, metoclopramide and chlorpromazine, using an in vitro model of the blood-brain barrier.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: Animals; Animals, Newborn; Antiemetics; Blood-Brain Barrier; Brain; Capillary Permeability; Cells, Cultured; Chlorpromazine; Claudin-1; Coculture Techniques; Domperidone; Endothelial Cells; Endothelium, Vascular; Isonipecotic Acids; Membrane Proteins; Metoclopramide; Neuroglia; Occludin; Phosphoproteins; Rats; Sucrose; Tight Junctions; Zonula Occludens-1 Protein

2007
Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
    The journal of physical chemistry. B, 2018, 12-13, Volume: 122, Issue:49

    Topics: Cell Membrane Permeability; Chlorpromazine; Desipramine; Domperidone; Kinetics; Labetalol; Lipid Bilayers; Loperamide; Molecular Dynamics Simulation; Molecular Structure; Propranolol; Thermodynamics; Verapamil

2018