chlorpromazine and dihydrexidine

chlorpromazine has been researched along with dihydrexidine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brewster, WK; Mailman, RB; Mottola, D; Nichols, DE; Riggs, RM; Watts, VJ1
Ghosh, D; Mailman, RB; Nichols, DE; Snyder, SE; Watts, VJ1
Mailman, RB; Negash, K; Nichols, DE; Watts, VJ1
Chemel, BR; Cueva, JP; Giorgioni, G; Grubbs, RA; Nichols, DE; Watts, VJ1
Cueva, JP; Gallardo-Godoy, A; Juncosa, JI; Lill, MA; Nichols, DE; Vidi, PA; Watts, VJ1
Clark, AH; McCorvy, JD; Nichols, DE; Watts, VJ1
Chemel, BR; Cueva, JP; Juncosa, JI; Lill, MA; Nichols, DE; Watts, VJ1
Bekkam, M; Clark, AH; Conley, JM; McCorvy, JD; Nichols, DE; Watts, VJ; Williams, WK1

Other Studies

8 other study(ies) available for chlorpromazine and dihydrexidine

ArticleYear
Evaluation of cis- and trans-9- and 11-hydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridines as structurally rigid, selective D1 dopamine receptor ligands.
    Journal of medicinal chemistry, 1995, Jan-20, Volume: 38, Issue:2

    Topics: Animals; Binding, Competitive; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Ligands; Male; Phenanthridines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

1995
9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: a potent full dopamine D1 agonist containing a rigid-beta-phenyldopamine pharmacophore.
    Journal of medicinal chemistry, 1996, Jan-19, Volume: 39, Issue:2

    Topics: Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Isoquinolines; Macaca mulatta; Male; Naphthols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Tumor Cells, Cultured

1996
Further definition of the D1 dopamine receptor pharmacophore: synthesis of trans-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphth[2,1-b]azepines as rigid analogues of beta-phenyldopamine.
    Journal of medicinal chemistry, 1997, Jul-04, Volume: 40, Issue:14

    Topics: Animals; Computer Simulation; Corpus Striatum; Dopamine Agonists; Indicators and Reagents; Models, Molecular; Molecular Conformation; Molecular Structure; Phenanthridines; Rats; Receptors, Dopamine D1; Software; Spiperone; Structure-Activity Relationship

1997
trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist.
    Journal of medicinal chemistry, 2006, Nov-16, Volume: 49, Issue:23

    Topics: Animals; Benzopyrans; Binding, Competitive; Cell Line; Corpus Striatum; Crystallography, X-Ray; Cyclic AMP; Humans; In Vitro Techniques; Isoquinolines; Molecular Structure; Phenanthridines; Psychotropic Drugs; Radioligand Assay; Rats; Receptors, Dopamine D1; Stereoisomerism; Structure-Activity Relationship; Swine

2006
Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues.
    Journal of medicinal chemistry, 2011, Aug-11, Volume: 54, Issue:15

    Topics: Binding Sites; Computer Simulation; Dopamine Agonists; Humans; Models, Molecular; Phenanthridines; Protein Binding; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

2011
Assessment of dopamine D₁ receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393.
    Bioorganic & medicinal chemistry, 2011, Sep-15, Volume: 19, Issue:18

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Models, Molecular; Molecular Conformation; Receptors, Dopamine D1; Stereoisomerism; Structure-Activity Relationship

2011
Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines.
    European journal of medicinal chemistry, 2012, Volume: 48

    Topics: Animals; Corpus Striatum; Dopamine Agonists; Isoquinolines; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phenanthridines; Receptors, Dopamine D1; Structure-Activity Relationship; Swine

2012
Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D₃ receptor-selective full agonist ligand.
    Bioorganic & medicinal chemistry, 2012, Nov-01, Volume: 20, Issue:21

    Topics: Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Models, Molecular; Molecular Conformation; Quinolines; Receptors, Dopamine D3; Structure-Activity Relationship

2012