chlorpromazine and digoxin

chlorpromazine has been researched along with digoxin in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (31.25)	18.7374
1990's	2 (6.25)	18.2507
2000's	7 (21.88)	29.6817
2010's	12 (37.50)	24.3611
2020's	1 (3.13)	2.80

Authors

Authors	Studies
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Romankiewicz, JA	1
Phillips, WA; Ratchford, JM; Schultz, JR	1
Aronson, JK; Boulin, DJ; Grahame-Smith, DG; Orr, MW	1
Bravo, G; Castañeda-Hernández, G; Godfraind, T	1
Martin, T; Mitema, ES; Sangiah, S	1
Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y	1
Bagdon, RE; Højelse, F; Svendsen, O	1
Bailey, LE; Dresel, PE; Kim, ND	1
Kuschinsky, K	1
Hurley, JV; Ryan, GB	1
Chambers, CA; Naylor, GJ; Smith, AH	1
Kuusi, T; Mäkelä, A; Schröder, T	1
Chiang, TK; Kurup, SK; White, KM; Yu, M	1

Reviews

2 review(s) available for chlorpromazine and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Use of Visual Electrophysiology to Monitor Retinal and Optic Nerve Toxicity. Biomolecules, 2022, 09-29, Volume: 12, Issue:10 Topics: Amiodarone; Cefuroxime; Chlorpromazine; Cisplatin; Deferoxamine; Digoxin; Electrophysiology; Ethambutol; Evoked Potentials, Visual; Humans; Hydroxychloroquine; Isotretinoin; Optic Nerve; Phosphodiesterase 5 Inhibitors; Quinine; Retina; Tamoxifen; Thioridazine; Topiramate; Vigabatrin	2022

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Use of Visual Electrophysiology to Monitor Retinal and Optic Nerve Toxicity.

Biomolecules, 2022, 09-29, Volume: 12, Issue:10

Topics: Amiodarone; Cefuroxime; Chlorpromazine; Cisplatin; Deferoxamine; Digoxin; Electrophysiology; Ethambutol; Evoked Potentials, Visual; Humans; Hydroxychloroquine; Isotretinoin; Optic Nerve; Phosphodiesterase 5 Inhibitors; Quinine; Retina; Tamoxifen; Thioridazine; Topiramate; Vigabatrin

2022

Trials

1 trial(s) available for chlorpromazine and digoxin

Article	Year
The effect of digoxin on the response to lithium therapy in mania. Psychological medicine, 1982, Volume: 12, Issue:1 Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Middle Aged; Nitrazepam; Random Allocation	1982

Other Studies

29 other study(ies) available for chlorpromazine and digoxin

Article	Year
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Effects of antacids on gastrointestinal absorption of drugs. Primary care, 1976, Volume: 3, Issue:3 Topics: Animals; Antacids; Aspirin; Chlordiazepoxide; Chlorpromazine; Dicumarol; Digitoxin; Digoxin; Ephedrine; Guinea Pigs; Humans; Intestinal Absorption; Iron; Isoniazid; Levodopa; Naproxen; Pentobarbital; Pharmaceutical Preparations; Quinidine; Quinine; Rats; Sulfadiazine; Tetracyclines; Warfarin	1976
Effects of colestipol hydrochloride on drug absorption in the rat II. Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:9 Topics: Animals; Cellulose; Chlorpromazine; Cholestyramine Resin; Clofibrate; Colestipol; Digitoxin; Digoxin; Hydrochlorothiazide; Intestinal Absorption; Male; Nicotinic Acids; Pharmaceutical Preparations; Phenobarbital; Polyamines; Rats; Tetracycline; Warfarin	1976
Proceedings: Cellular biochemical pharmacology in monitoring drug therapy. Arzneimittel-Forschung, 1976, Volume: 26, Issue:6 Topics: Chlorpromazine; Digoxin; Humans; Platelet Aggregation; Schizophrenia	1976
Chlorpromazine treatment increases circulating digoxin like immunoreactivity in the rat. Proceedings of the Western Pharmacology Society, 1991, Volume: 34 Topics: Animals; Blood Proteins; Cardenolides; Chlorpromazine; Digoxin; Female; Radioimmunoassay; Rats; Rats, Inbred Strains; Saponins	1991
Effects of some calcium modulators on monensin toxicity. Veterinary and human toxicology, 1988, Volume: 30, Issue:5 Topics: Animals; Calcium; Calcium Channel Blockers; Chlorpromazine; Digoxin; Lethal Dose 50; Male; Mice; Monensin; Sodium; Tolazoline	1988
Effects of basic drugs on the hepatic transport of cardiac glycosides in rats. Biochemical pharmacology, 1988, Aug-01, Volume: 37, Issue:15 Topics: Animals; Anti-Arrhythmia Agents; Cardiac Glycosides; Cells, Cultured; Chlorpromazine; Digoxin; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Ouabain; Rats; Rats, Inbred Strains; Vasodilator Agents	1988
Tests for local toxicity of intramuscular drug preparations: comparison of in vivo and in vitro methods. Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2 Topics: Animals; Chlorpromazine; Clopenthixol; Creatine Kinase; Digoxin; Female; Hemolysis; In Vitro Techniques; Injections, Intramuscular; Male; Muscles; Rabbits	1985
Correlation of the subcellular distribution of digoxin with the positive inotropic effect. The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:2 Topics: Aldosterone; Animals; Carbon Isotopes; Cell Nucleus; Chlorpromazine; Chromatography, Gel; Digoxin; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Inulin; Male; Microsomes; Mitochondria, Muscle; Muscle Contraction; Myocardium; Perfusion; Protein Binding; Tritium	1972
The specifity of the binding of some cardenolides to human serum albumin. Arzneimittel-Forschung, 1970, Volume: 20, Issue:6 Topics: Binding Sites; Cardiac Glycosides; Chlorpromazine; Digitoxin; Digoxin; Humans; Penicillin G; Potassium; Protein Binding; Serum Albumin; Solvents; Sulfadiazine; Sulfonamides; Suramin; Thiopental; Tritium	1970
The drug inhibition of increased vascular permeability. The Journal of pathology and bacteriology, 1968, Volume: 96, Issue:2 Topics: Animals; Blood Vessels; Burns; Capillary Permeability; Chlorpromazine; Digoxin; Diphenhydramine; Indomethacin; Inflammation; Male; Permeability; Promethazine; Quinine; Rats; Salicylates; Strophanthins; Tissue Extracts; Turpentine	1968
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro. Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5 Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Chlorpromazine; Digoxin; Enzyme Inhibitors; Glucocorticoids; Humans; Lidocaine; Pancreatitis; Phospholipases A; Phospholipases A2	1997