chlorpromazine has been researched along with desipramine in 268 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 194 (72.39) | 18.7374 |
| 1990's | 6 (2.24) | 18.2507 |
| 2000's | 29 (10.82) | 29.6817 |
| 2010's | 36 (13.43) | 24.3611 |
| 2020's | 3 (1.12) | 2.80 |
| Authors | Studies |
|---|---|
| Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Chiang, GH; Unger, SH | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Faller, B; Wohnsland, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Keserü, GM | 1 |
| Caron, G; Ermondi, G | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Briand, X; Faller, B; Lázaro, E; Lowe, PJ | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, ZF; Huang, SL; Huang, ZS; Liang, H; Qin, JK; Tang, H; Zhao, HT; Zhao, LZ; Zhong, SM | 1 |
| Chen, ZF; Liang, H; Tang, H; Wang, ZY; Zhao, HT; Zhong, SM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, J; Chen, X; Huang, L; Li, X; Sun, Y | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R | 1 |
| Huang, L; Li, X; Meng, F; Miao, H; Sun, Y | 1 |
| Goetz, GH; Philippe, L; Shapiro, MJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Chen, W; Huangli, Y; Qin, J; Shen, Y; Tang, H; Wang, L; Wei, S | 1 |
| Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Bibak, N; Blaess, M; Bonaterra, GA; Claus, RA; Deigner, HP; Kinscherf, R; Kohl, M; Laufer, S | 1 |
| Chreifi, G; Do, HT; Li, H; Poulos, TL; Silverman, RB; Wang, HY | 1 |
| Dolezal, R; Hepnarova, V; Hrabinova, M; Jost, P; Jun, D; Kaping, D; Kerhartova, M; Korabecny, J; Kuca, K; Kucera, T; Matouskova, L; Mezeiova, E; Muckova, L; Nepovimova, E; Pham, NL; Soukup, O; Spilovska, K; Staud, F; Vykoukalova, N | 1 |
| An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T | 1 |
| Chen, L; Chen, Y; Duan, Y; Feng, F; Huang, J; Jiang, X; Liu, C; Liu, W; Qu, W; Sun, H; Wang, Y; Zhou, J | 1 |
| Chen, T; Chen, Y; Feng, F; Jiang, X; Li, Q; Liu, C; Liu, W; Lyu, W; Sun, H; Wang, S; Wang, Y; Xing, C | 1 |
| Hardy, CD; Li, H; Poulos, TL; Silverman, RB; Vasu, D | 1 |
| Modestin, J; Petrin, A | 1 |
| Buckle, P; Jameson, D | 1 |
| Løvstad, RA | 1 |
| Biegon, A; Samuel, D | 1 |
| Huh, K; Iwata, H; Yamamoto, I | 1 |
| Baba, A; Iwata, H; Matsuda, T; Terashita, Z | 1 |
| Hollander, CS; Tai, HH | 1 |
| McIlwain, H | 1 |
| Keim, KL; Sigg, EB | 1 |
| Annau, Z; Simpson, DM | 1 |
| Mosnaim, AD; Ungar, B; Ungar, F; Wolf, ME | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Key, BJ; Krzywosinski, L | 1 |
| Bareggi, SR; Genovese, E; Markey, K | 1 |
| Biegon, A; Samuel, D; Segal, M; Yavin, Z | 1 |
| Chen, CS; Ozawa, H; Uematsu, T; Watanabe, H | 1 |
| Davis, CM; Fenimore, DC; Hsu, F; Meyer, CJ; Zlatkis, A | 1 |
| Ozawa, H; Uematsu, T | 1 |
| Henry, BW; Overall, JE; Woodward, JA | 1 |
| Krupp, P; Wesp, M | 1 |
| Oksenkrug, GF | 1 |
| McIlwain, H; Pull, I | 1 |
| Saltz, BL | 1 |
| Chessler, RK; Elias, S; Patel, YJ; Scherl, ND; Zingler, BM | 1 |
| Melzacka, M; Nocon, H | 1 |
| Kiryon, C; Miki, A; Nakayama, T; Ohsawa, K; Tanabe, K | 1 |
| Hegenscheid, B; Presber, HW | 1 |
| Sieber-Blum, M | 1 |
| McElroy, JF; O'Donnell, JM | 1 |
| Cools, AR; Ellenbroek, BA; Honig, WM; Peeters, BW | 1 |
| Hauser, G; Leli, U | 3 |
| Hauser, G; Koul, O | 1 |
| Bouthillier, A; de Montigny, C | 1 |
| Della Corte, L; Giovannini, MG; Ninci, R; Sgaragli, G | 1 |
| Duffin, SR; Hunt, LM; Yagiela, JA | 1 |
| Prange, AJ | 1 |
| Albouz, S; Baumann, N; Hauw, JJ; Le Saux, F; Wenger, D | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| Tuomisto, J | 1 |
| Schmutz, J | 1 |
| Hishikawa, Y; Ida, H; Kaneko, Z; Nakai, K | 1 |
| Mandell, AJ; Spooner, CE; Wallach, MB; Winters, WD | 2 |
| Barthel, W | 1 |
| Baltzer, V; Bein, HJ | 1 |
| Bolan, JC; Glenn, CH; Hardison, MD; Mason, RG; Mohammad, SF; Morton, BD | 1 |
| Berti, F; Shore, PA | 1 |
| Iversen, LL; Kravitz, EA | 1 |
| Glasser, H; Krieglstein, J | 1 |
| Askari, A; Rao, SN | 1 |
| Bickel, MH; Minder, R; Schnetzer, F | 1 |
| Medzihradsky, F; Nandhasri, PS | 1 |
| Franz, DN; Hare, BD; Neumayr, RJ | 1 |
| Maxwell, DR; Sumpter, EA | 1 |
| Zingales, I | 1 |
| Ellaway, PH; Pascoe, JE | 1 |
| Hartmann, E | 1 |
| Abraham, AD; Holan, TS; Pora, EA; Uray, Z | 1 |
| Kodama, T; Matsukado, Y; Shimizu, H; Suzuki, T; Tanaka, S | 1 |
| Kaniike, K; Kurogochi, Y | 1 |
| Valzelli, L | 2 |
| Chang, CC; Chuang, ST | 1 |
| Doggett, NS; Spencer, PS | 1 |
| Berndt, S; Schwabe, U | 1 |
| Baba, A; Ishii, K; Iwata, H; Matsuda, T; Terashita, Z | 1 |
| Gaut, ZN | 2 |
| Mlejnkova, M; Rysánek, K; Spánkova, H; Synek, P | 1 |
| Renyi, AL; Ross, SB | 1 |
| Iversen, LL | 2 |
| Green, AL | 1 |
| Garattini, S; Jori, A; Paglialunga, S | 1 |
| Breese, GR; Kopin, IJ; Schanberg, SM; Schildkraut, JJ | 2 |
| Garattini, S; Hrdina, P | 1 |
| Garattini, S; Jori, A | 1 |
| Heiss, WD | 1 |
| Annoni, F; Bianchetti, A; Jori, A | 1 |
| Dixon, AK | 1 |
| Vapaatalo, HI | 1 |
| Colson, SH; Tolson, WW; Umberger, EJ | 1 |
| Iversen, LL; Johnston, GA | 2 |
| Bickel, MH | 1 |
| Clark, B; Thompson, JW; Widdrington, G | 1 |
| Consolo, S; Garattini, S; Ladinsky, H; Peri, G | 1 |
| Karobath, M | 1 |
| Constatinidis, J | 1 |
| Komissarov, IV; Talalaenko, AN; Zin'kovskaia, LIa | 1 |
| Christiansen, J; Gram, LF; Overo, KF | 1 |
| Lin, RL; Narasimhachari, N | 1 |
| Davila, D; Palaić, D; Rabadija, M; Supek, Z | 1 |
| Gripenberg, J | 1 |
| Andersen, PR; Gibbs, P; Kubinski, H | 1 |
| Biel, JH; Bopp, B | 1 |
| Cooper, F; Leonard, BE; Schnieden, H | 1 |
| König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P | 1 |
| Jonsson, G; Sachs, C | 1 |
| Mann, WA; Ridley, PT | 1 |
| Alexander, L | 1 |
| Jacobwitz, D; Kostrzewa, R | 1 |
| Carmichael, FJ; Israel, Y | 1 |
| Connor, JD; Crawford, IL; Pardridge, WM | 1 |
| Korduba, CA; Symchowicz, S; Veals, J | 1 |
| Boulu, R; Dupeyron, JP; Rossignol, P | 1 |
| Lee, RE | 1 |
| Lassen, JB | 1 |
| Mattila, MJ; Saarnivaara, L | 1 |
| Bellward, GD; Black, NB; Dayton, PG; O'Brien, L; Perel, JM | 1 |
| Clark, ML; Conway, MW; Kaul, PN | 1 |
| Gessa, GL; Tagliamonte, A | 1 |
| Furlong, FW; Luby, ED | 1 |
| Gelb, F; Gurfein, L; Kammerer, M; Wartel, R; Weil, J; Wysoki, V | 1 |
| Lomax, P | 1 |
| Baker, WW; Kratky, M | 1 |
| Hollister, LE; Overall, JE | 1 |
| Hori, S; Inouye, A; Kataoka, K; Sorimachi, M | 1 |
| Mainard, F; Stephan, Y; Welin, L | 1 |
| Constantine, JW; Koe, BK | 1 |
| Scheel-Krüger, J | 1 |
| Cooper, F; Schnieden, H | 1 |
| Baran, L; Maj, J; Sowińska, H | 1 |
| Garriott, JC; Stolman, A | 1 |
| Oates, JA; Shand, DG | 1 |
| Iriye, TT; Simmonds, FA | 1 |
| Nordgren, L | 1 |
| Blackburn, KJ; French, PC; Merrills, RJ | 1 |
| Brown, RM; Lal, H | 1 |
| Hitomi, M; Kumada, S; Kumadaki, N | 1 |
| Bhargava, KP; Dixit, KS; Sinha, JN; Srimal, RC | 1 |
| Lapin, IP; Osipova, SV; Stabrovski, EM; Uskova, NV | 2 |
| Burghardt, C; Sheppard, H; Tsien, WH | 1 |
| Rohte, O | 3 |
| Gross, R; Linker, H; Reuter, H | 1 |
| Fischbach, R | 1 |
| Núnek, K | 1 |
| Foxwell, MH; Funderburk, WH; Hakala, MW | 1 |
| Chenoweth, MB; Schneider, CW | 1 |
| Bartakovits, P; Mann, WA; Miller, DA; Pendleton, RG; Ridley, PT | 1 |
| Lippmann, W | 1 |
| Izquierdo, JA; Laguzzi, RF | 1 |
| Breese, GR; Traylor, TD | 1 |
| Whittle, BA | 1 |
| Axelrod, J; Eccleston, D; Thoa, NB | 1 |
| Anton-Tay, F; Axelrod, J; Wurtman, RJ | 1 |
| Nybäck, H; Sedvall, G | 1 |
| Borzecki, Z; Nybäck, H; Sedvall, G | 1 |
| Milner, G | 1 |
| Chase, TN; Katz, RI; Kopin, IJ | 1 |
| Scriabine, A | 1 |
| Heilig, P; Heiss, WD; Hoyer, J | 2 |
| Shillito, EE | 1 |
| Feller, DR; Finger, KF; Page, JG | 1 |
| Baldessarini, RJ; Kopin, IJ | 1 |
| Arimura, A; Müller, EE; Saito, T; Schally, AV | 1 |
| Kopin, IJ; Schanberg, SM; Schildkraut, JJ | 1 |
| Babbini, M; Cestari, A; De Marchi, F; Graziani, G | 1 |
| Schechter, MD | 1 |
| Logan, JG; O'Donovan, DJ | 1 |
| Cardinal, JA; Hill, AG; Midha, KK; Verbeeck, RK | 1 |
| Borsini, F; Nowakowska, E; Samanin, R | 1 |
| Borghgraef, R; De Smedt, H; Paulussen-Noterman, N | 1 |
| Edström, A; Ekström, P; Kanje, M | 1 |
| Chang, RS; Kling, P; Lotti, VJ | 1 |
| Scuvée-Moreau, JJ; Svensson, TH | 1 |
| Gaillard, JM; Justafre, JC; Kafi, S | 1 |
| Cardinal, JA; Verbeeck, RK; Wallace, SM | 1 |
| Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S | 1 |
| Chung, C; Cook, P; Pendleton, RG; Risley, E; Williams, M | 1 |
| Nobrega, JN; Wiener, NI | 1 |
| Jones, RS; Olpe, HR; Steinmann, MW | 1 |
| Chan, MY; Hung, F | 2 |
| Hirschmann, N; Nir, I | 1 |
| Andersson, A; Olsson, S; Tjälve, H | 1 |
| Anene, BM; Anika, SM; Chukwu, CC; Ross, CA | 1 |
| Kimura, H; Matsumoto, K; Mukaida, M; Wang, G; Yuan, J | 1 |
| Donati, RJ; Rasenick, MM; Thukral, C | 1 |
| GYERMEK, L; SIGG, EB; SOFFER, L | 1 |
| ALNAES, R; KRISTIANSEN, J | 1 |
| BOFF, E; SCHECKEL, CL | 1 |
| BUECH, O; KUNZ, HA; MORPURGO, C; STENGER, EG; THEOBALD, W; WILHELMI, G | 1 |
| LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA | 1 |
| HOLLISTER, LE | 1 |
| TAIT, AC; TODRICK, A; YATES, CM | 1 |
| BOWEN, LW | 1 |
| HALLIWELL, G; QUINTON, RM; WILLIAMS, FE | 1 |
| JACOBSON, J; URSILLO, RC | 1 |
| METYS, J; METYSOVA, J; VOTAVA, Z | 1 |
| FUKS, Z; LANMAN, RC; SCHANKER, LS | 1 |
| Pei, Q; Sharp, T; Sprakes, M; Tordera, R; Zetterström, TS | 1 |
| Barygin, OI; Belinskaya, DA; Nagaeva, EI; Shestakova, NN; Tikhonov, DB; Vanchakova, NP | 1 |
| Badaoui, M; Dickson, CJ; Hornak, V; Kells, A; Molteni, C; Rosta, E | 1 |
11 review(s) available for chlorpromazine and desipramine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine | 1976 |
Transport of adenine derivatives in tissues of the brain.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Biological Transport; Brain; Chlorpromazine; Cyclic AMP; Desipramine; Electric Stimulation; Glutamates; Guinea Pigs; Hypoxanthines; In Vitro Techniques; Mice; Pentobarbital | 1976 |
Psychotropic drugs and the thyroid axis: a review of interactions.
Topics: Animals; Body Temperature; Brain; Chlorpromazine; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Imipramine; Male; Mice; Psychotropic Drugs; Schizophrenia; Thyroid Gland; Thyroid Hormones; Triiodothyronine | 1985 |
[Intention and incident in drug research, demonstrated on the example of tricyclic psychopharmacologic agents].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Azepines; Chemical Phenomena; Chemistry; Chlorpromazine; Desipramine; Humans; Imipramine; Mental Disorders; Research; Structure-Activity Relationship; Tranquilizing Agents | 1973 |
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan | 1969 |
Psychoactive drugs and brain neurochemical transmitters.
Topics: Amphetamine; Antidepressive Agents; Butyrophenones; Chlorpromazine; Deamination; Desipramine; Dihydroxyphenylalanine; Methylation; Neurons; Norepinephrine; Phenothiazines; Receptors, Drug; Reserpine; Synapses; Synaptic Transmission; Tyrosine | 1972 |
Antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Carbazoles; Chlorpromazine; Desipramine; Imipramine; Molecular Conformation; Opipramol; Structure-Activity Relationship; Tripelennamine | 1974 |
Drugs and body temperature.
Topics: Acetylcholine; Amines; Amphetamine; Analgesics; Anesthetics; Animals; Behavior; Body Temperature Regulation; Cats; Central Nervous System; Chlorpromazine; Desipramine; Environment; Hormones; Humans; Hypothalamus; Imidazoles; Lysergic Acid Diethylamide; Mice; Morphine; Parasympathomimetics; Pyrogens; Rabbits; Sheep; Species Specificity; Sweating; Vasomotor System | 1970 |
Indications for tricyclic antidepressant drugs.
Topics: Antidepressive Agents; Chlorpromazine; Depression; Desipramine; Drug Interactions; Humans; Imipramine; Phenothiazines; Time Factors | 1971 |
2 trial(s) available for chlorpromazine and desipramine
| Article | Year |
|---|---|
Lithium in the control of mania.
Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine | 1967 |
[Clinical experimentation with desipramine with statistical control].
Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Depression; Desipramine; Diazepam; Haloperidol; Humans; Methotrimeprazine; Middle Aged; Schizophrenia | 1968 |
255 other study(ies) available for chlorpromazine and desipramine
| Article | Year |
|---|---|
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Aporphines; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Models, Biological; Tacrine | 2011 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Membranes, Artificial; Models, Molecular; Molecular Structure; Permeability; Protein Binding | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface | 2014 |
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates | 2014 |
EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides.
Topics: | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Autophagy; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species | 2017 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation.
Topics: Apoptosis; Cell Line; Cells, Cultured; Ceramides; Enzyme Inhibitors; Humans; Inflammation; Lipopolysaccharides; Lysosomes; Macrophages; Signal Transduction; Sphingomyelin Phosphodiesterase | 2018 |
Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.
Topics: Aminopyridines; Animals; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Fluorobenzenes; Humans; Mice; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Structure-Activity Relationship; Swine; Theophylline; Verapamil | 2017 |
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line; Cholinesterase Inhibitors; Cricetulus; Dose-Response Relationship, Drug; Humans; Molecular Structure; Quinolines; Structure-Activity Relationship; Tacrine | 2018 |
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram | 2019 |
Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease.
Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Glycogen Synthase Kinase 3; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Morris Water Maze Test; Phosphorylation; Protein Conformation; tau Proteins; Thiazoles | 2020 |
Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Glycogen Synthase Kinase 3 beta; Humans; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Pyridines; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2021 |
2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Topics: Aminopyridines; Animals; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Protein Isoforms; Rats | 2022 |
A comparison of anti-inflammatory and other compounds on the spontaneously contracting pregnant rat uterus.
Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Desipramine; Diazepam; Female; In Vitro Techniques; Ketamine; Muscle, Smooth; Papaverine; Pregnancy; Pregnancy, Animal; Rats; Uterine Contraction | 1977 |
Effect of centrally active drugs on dopamine oxidation by rat brain catecholamine oxidase.
Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Female; Haloperidol; Imipramine; Kinetics; Promazine; Rats; Thioridazine; Trifluoperazine; Trifluperidol | 1979 |
The in vivo distribution of an antidepressant drug (DMI) in male and female rats.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Female; Kinetics; Liver; Male; Rats; Sex Factors; Time Factors; Tissue Distribution | 1979 |
[Hepatic allopurinol oxidizing enzyme in mice].
Topics: Aldehyde Oxidoreductases; Allopurinol; Animals; Chlorpromazine; Desipramine; Dexamethasone; Dialysis; Diphenhydramine; Hot Temperature; Imipramine; Ions; Liver; Male; Mice; Niacinamide; Oxypurinol; Testosterone; Time Factors; Vitamin K; Xanthine Oxidase | 1975 |
Properties of thiamine di- and triphosphatases in rat brain microsomes: effects of chlorpromazine.
Topics: Acetone; Animals; Brain; Calcium; Chlorpromazine; Deoxycholic Acid; Desipramine; Imipramine; Kinetics; Magnesium; Male; Microsomes; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Pyrophosphatases; Rats; Thiamine; Thiamine Pyrophosphatase | 1975 |
Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs.
Topics: Alcohol Oxidoreductases; Amitriptyline; Animals; Chlorpromazine; Desipramine; Dibenzocycloheptenes; Enzyme Activation; Hydroxyprostaglandin Dehydrogenases; Imipramine; Kidney; Kinetics; NAD; Protriptyline; Swine | 1976 |
Plasma corticosterone and brain catecholamines in stress: effect of psychotropic drugs.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Corticosterone; Desipramine; Diazepam; Dopamine; Haloperidol; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Pargyline; Phenobarbital; Prohibitins; Psychotropic Drugs; Rats; Stress, Physiological; Telencephalon | 1977 |
Behavioral withdrawal following several psychoactive drugs.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Dextroamphetamine; Electric Stimulation; Humans; Iproniazid; Male; Psychotropic Drugs; Rats; Self Stimulation; Stereotaxic Techniques; Substance Withdrawal Syndrome | 1977 |
Tyramine-binding by synaptosomes from rat brain: effect of centrally active drugs.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Dextroamphetamine; Diphenhydramine; Male; Morphine; Rats; Synaptosomes; Tyramine | 1977 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Comparison of the electrocortical changes induced by (+)-amphetamine and chlorpromazine when perfused directly into the dorsal raphé nucleus of the cat.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dextroamphetamine; Drug Interactions; Electroencephalography; Guanethidine; Norepinephrine; Perfusion; Raphe Nuclei | 1978 |
Effects of single and multiple doses of desipramine (DMI) on endogenous levels of 3-methoxy-4-hydroxyphenylglycol-sulfate (MOPEG-SO4) in rat brain.
Topics: Animals; Brain Chemistry; Chlorpromazine; Desipramine; Drug Interactions; Electric Stimulation; Glycols; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenoxybenzamine; Rats; Time Factors | 1978 |
The in vivo binding of [3H]-desipramine and [3H]-chlorpromazine to areas in the rat brain.
Topics: Animals; Autoradiography; Brain; Chlorpromazine; Desipramine; Hydroxydopamines; Male; Rats; Time Factors | 1978 |
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipramine; Drug Synergism; Guanethidine; Heart Rate; Hexamethonium Compounds; Injections, Intravenous; Injections, Subcutaneous; Male; Phentolamine; Rats; Reserpine | 1977 |
High-performance thin-layer chromatographic determination of psychopharmacologic agents in blood serum.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1977 |
Centrally mediated cardiovascular effects of intracisternal application of carbachol in anesthetized rats.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Cisterna Magna; Desipramine; Drug Interactions; Hemodynamics; Hexamethonium Compounds; Injections; Male; Parasympathomimetics; Propranolol; Rats; Sympatholytics; Vagus Nerve | 1976 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Inhibition of prostaglandin synthetase by psychotropic drugs.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Centrally-acting drugs and related compounds examined for action on output of adenine derivatives from superfused tissues of the brain.
Topics: Adenine; Adenine Nucleotides; Amobarbital; Animals; Brain; Chlorpromazine; Desipramine; Guinea Pigs; Imipramine; In Vitro Techniques; Lactates; Phenytoin; Psychotropic Drugs | 1976 |
Tardive dyskinesia in the elderly patient.
Topics: Aged; Chlorpromazine; Chronic Disease; Clonazepam; Clozapine; Depressive Disorder; Desipramine; Diphenhydramine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Neurologic Examination | 1992 |
Ischemic colitis associated with psychotropic drugs.
Topics: Adult; Chlorpromazine; Colitis; Colon; Desipramine; Female; Humans; Imipramine; Ischemia | 1992 |
Effect of some cationic amphiphilic drugs on phospholipid methylation in the central nervous system of rats.
Topics: Animals; Cerebral Cortex; Chlorpromazine; Citalopram; Desipramine; Imipramine; Injections, Intraperitoneal; Male; Methylation; Methyltransferases; Phospholipids; Rats; Rats, Inbred Strains; Synaptic Membranes | 1991 |
Plasmodium chabaudi: association of reversal of chloroquine resistance with increased accumulation of chloroquine in resistant parasites.
Topics: Animals; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Chromatography, High Pressure Liquid; Desipramine; Drug Resistance; Erythrocytes; Female; Imipramine; Malaria; Mice; Mice, Inbred ICR; Plasmodium chabaudi; Trifluoperazine | 1992 |
[Antiprotozoal effects of benzodiazepine derivatives].
Topics: Animals; Benzodiazepines; Chlorpromazine; Clomipramine; Crithidia; Desipramine; Eukaryota; Imipramine; Leishmania mexicana; Metronidazole; Trichomonas vaginalis; Trypanosoma cruzi | 1990 |
Inhibition of the adrenergic phenotype in cultured neural crest cells by norepinephrine uptake inhibitors.
Topics: Adrenergic Fibers; Animals; Biological Transport; Chlorpromazine; Citalopram; Coturnix; Desipramine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Mazindol; Neural Crest; Neurotransmitter Uptake Inhibitors; Norepinephrine; Tyrosine 3-Monooxygenase | 1989 |
Discriminative stimulus properties of clenbuterol: evidence for beta adrenergic involvement.
Topics: Albuterol; Amphetamine; Animals; Chlorpromazine; Clenbuterol; Desipramine; Discrimination Learning; Dose-Response Relationship, Drug; Ethanolamines; Haloperidol; Isomerism; Male; Pentylenetetrazole; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1988 |
The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Forelimb; Haloperidol; Hindlimb; Male; Metoclopramide; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Thioridazine | 1987 |
Chlorpromazine induces accumulation of inositol phosphates in C6 glioma cells.
Topics: Animals; Cell Line; Chlorpromazine; Desipramine; Glioma; Inositol; Inositol Phosphates; Lysophospholipids; Phosphatidylinositols; Propranolol; Rats; Sugar Phosphates | 1986 |
Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells.
Topics: Animals; Cell Line; Chlorpromazine; Desipramine; Diglycerides; Dose-Response Relationship, Drug; Glioma; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Propranolol; Tetradecanoylphorbol Acetate | 1987 |
Modulation of rat brain cytosolic phosphatidate phosphohydrolase: effect of cationic amphiphilic drugs and divalent cations.
Topics: Animals; Brain; Cations; Chlorpromazine; Cytosol; Desipramine; Kinetics; Male; Microscopy, Electron; Microsomes, Liver; Phosphatidate Phosphatase; Phosphoric Monoester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Sonication | 1987 |
Long-term antidepressant treatment reduces neuronal responsiveness to flurazepam: an electrophysiological study in the rat.
Topics: Acetylcholine; Action Potentials; Animals; Antidepressive Agents; Chlorpromazine; Cholecystokinin; Citalopram; Desipramine; Flurazepam; Hippocampus; Iontophoresis; Male; Propylamines; Rats; Rats, Inbred Strains; Time Factors; Trimipramine | 1987 |
Isothermal gas chromatographic determination of nanogram amounts of chlorimipramine, chlorpromazine and their N-desmethyl metabolites in plasma using nitrogen-selective detection.
Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Desipramine; Humans; Indicators and Reagents | 1986 |
Mechanism of modification of rat brain lysophospholipase A activity by cationic amphiphilic drugs.
Topics: Animals; Brain; Cations; Chlorpromazine; Cytosol; Desipramine; Fatty Acids, Nonesterified; Lysophospholipase; Micelles; Microscopy, Electron; Microsomes; Phospholipases; Propranolol; Psychotropic Drugs; Rats | 1987 |
Drug interactions and vasoconstrictors used in local anesthetic solutions.
Topics: Anesthetics, Local; Animals; Blood Pressure; Chlorpromazine; Desipramine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Heart Rate; Nordefrin; Norepinephrine; Phenelzine; Vasoconstrictor Agents | 1985 |
Modifications of sphingomyelin and phosphatidylcholine metabolism by tricyclic antidepressants and phenothiazines.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Line; Chlorpromazine; Desipramine; Dose-Response Relationship, Drug; Fibroblasts; Glioma; Humans; Imipramine; Kinetics; Lysosomes; Niemann-Pick Diseases; Phenothiazines; Phosphatidylcholines; Rats; Sphingomyelin Phosphodiesterase; Sphingomyelins | 1986 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine | 1974 |
The effect of imipramine, desmethylimipramine and chlorpromazine on the sleep-wakefulness cycle of the cat.
Topics: Animals; Cats; Cerebral Cortex; Chlorpromazine; Circadian Rhythm; Desipramine; Electroencephalography; Electromyography; Eye Movements; Imipramine; Sleep | 1965 |
A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cats; Chlorpromazine; Desipramine; Electroencephalography; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Seizures; Sleep; Wakefulness | 1969 |
Effects of antidepressant drugs on wakefulness and sleep in the cat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Chlorpromazine; Circadian Rhythm; Desipramine; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Sleep; Sleep Stages; Time Factors; Wakefulness | 1969 |
[The effect of drugs on the amine storage function of blood platelets].
Topics: Anesthetics, Local; Animals; Biological Transport; Blood Platelets; Catecholamines; Cell Membrane Permeability; Chlorpromazine; Cocaine; Desipramine; Histamine H1 Antagonists; Imipramine; Phenothiazines; Rabbits; Reserpine; Serotonin; Sympathomimetics; Tryptamines | 1969 |
Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent.
Topics: Adjuvants, Anesthesia; Aggression; Animals; Anthracenes; Cats; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Dogs; Haplorhini; Hemodynamics; Humans; Imipramine; Mice; Motor Neurons; Muscle Contraction; Rabbits; Rats; Reflex; Respiration; Seizures | 1973 |
Adhesion of human blood platelets to glass and polymer surfaces. I. Studies with platelets in plasma.
Topics: Adult; Age Factors; Amitriptyline; Aspirin; Blood Coagulation Disorders; Chloromercuribenzoates; Chlorpromazine; Citrates; Desipramine; Edetic Acid; Glass; Glucosamine; Heparin; Humans; Imipramine; Middle Aged; Platelet Adhesiveness; Polyethylenes; Polymers; Polytetrafluoroethylene; Polyvinyl Chloride; Promethazine; Sulfinpyrazone | 1974 |
A kinetic analysis of drugs that inhibit the adrenergic neuronal membrane amine pump.
Topics: Adenosine Triphosphatases; Animals; Bretylium Compounds; Cardiac Glycosides; Chlorpromazine; Cocaine; Desipramine; Energy Transfer; In Vitro Techniques; Kinetics; Membranes; Metaraminol; Myocardium; Neurons; Ouabain; Potassium; Rabbits; Sodium; Sympathetic Nervous System | 1967 |
The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system--uptake of GABA in the nerve-muscle preparations.
Topics: Aminobutyrates; Animals; Carbon Isotopes; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Crustacea; Desipramine; Extracellular Space; Glutamates; Kinetics; Muscle Spindles; Nervous System; Sodium; Synapses; Tritium | 1968 |
[Protein binding of some psychoactive drugs with a tricyclic ring system, as a function of their chemical constitution].
Topics: Acepromazine; Alcohols; Amitriptyline; Chemical Phenomena; Chemistry, Physical; Chlorpromazine; Chromatography, Gel; Desipramine; Dialysis; Dibenzazepines; Dibenzocycloheptenes; Imipramine; Phenothiazines; Promazine; Protein Binding; Serum Albumin, Bovine; Thiazines; Triflupromazine | 1970 |
Drugs affecting sodium transport in human erythrocyte ghosts.
Topics: Acetates; Adenosine Triphosphatases; Anesthetics, Local; Biological Transport, Active; Cell Membrane; Chlorpromazine; Desipramine; Dipyridamole; Erythrocytes; Ethacrynic Acid; Furosemide; Humans; Imipramine; Iodine; Lactates; Oligomycins; Ouabain; Potassium; Pyruvates; Sodium | 1970 |
Hepatic and extrahepatic metabolism of the psychotropic drugs, chlorpromazine, imipramine, and imipramine-N-oxide.
Topics: Adipose Tissue; Animals; Bile; Brain; Cecum; Chlorpromazine; Cyclic N-Oxides; Desipramine; Hepatectomy; Imipramine; Intestine, Small; Kidney; Liver; Lung; Male; Muscles; Myocardium; Rats; Rats, Inbred Strains; Skin; Spleen | 1971 |
Effects of some analgesics and antidepressants on the (Na + + K + )-adenosine triphosphatase from cortices of brain and kidney.
Topics: Adenosine Triphosphatases; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cattle; Cerebral Cortex; Chlorpromazine; Cyclazocine; Desipramine; Dose-Response Relationship, Drug; Hydralazine; Imipramine; In Vitro Techniques; Kidney; Kidney Cortex; Pentazocine; Phenazocine; Phenelzine; Potassium; Sodium; Tranylcypromine | 1972 |
Evidence for bulbospinal control of sympathetic preganglionic neurons by monoaminergic pathways.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Cats; Chloralose; Chlorpromazine; Computers; Desipramine; Dihydroxyphenylalanine; Electric Stimulation; Ethyl Ethers; Fenclonine; Ganglia, Autonomic; Microelectrodes; Neurons; Norepinephrine; Serotonin; Spinal Cord; Tryptophan | 1974 |
A comparison of the actions of some drugs on decerebrate rigidity, muscle spindle activity and alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dimethylamines; Dose-Response Relationship, Drug; Methotrimeprazine; Muscle Rigidity; Muscle Spindles; Nictitating Membrane; Norepinephrine; Phenothiazines; Receptors, Adrenergic; Serotonin Antagonists; Structure-Activity Relationship; Valerates | 1974 |
Systematic identification of psychotropic drugs by thin layer chromatography. II.
Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents | 1968 |
Noradrenaline as a transmitter in the spinal cord.
Topics: Animals; Catechols; Chlorpromazine; Cocaine; Desipramine; Electric Stimulation; Electrophysiology; Ergotamine; Methamphetamine; Norepinephrine; Phenoxybenzamine; Rabbits; Spinal Cord; Synaptic Transmission | 1968 |
Correlation between the radioprotective effect of some substances with neurotropic action and inhibition of the respiratory enzymes.
Topics: Chlorpromazine; Desipramine; Dibenzocycloheptenes; Electron Transport Complex IV; Imipramine; Mitochondria, Liver; Radiation-Protective Agents | 1970 |
Stimulated formation of adenosine 3',5'-monophosphate by desipramine in brain slices.
Topics: Adenine; Adenosine Triphosphate; Amitriptyline; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cyclic AMP; Desipramine; Guinea Pigs; Histamine; Imipramine; Male; Norepinephrine; Perphenazine; Phentolamine; Phosphoric Monoester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Theophylline; Tritium; Veratrine | 1971 |
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents | 1972 |
Effects of desipramine and imipramine on the nerve, muscle and synaptic transmission of rat diaphragms.
Topics: Acetylcholine; Action Potentials; Animals; Axons; Chlorpromazine; Desipramine; Diaphragm; Electric Stimulation; Imipramine; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Neuromuscular Junction; Neurons; Phrenic Nerve; Procaine; Rats; Stimulation, Chemical; Synaptic Transmission | 1972 |
Pharmacological properties of centrally-administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cyclic AMP; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Hydroxydopamines; Male; Mice; Mice, Inbred Strains; Morphine; Nialamide; Ouabain; Rats; Reaction Time; Synaptic Transmission; Tetrabenazine; Thiocarbamates; Time Factors | 1973 |
Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlorpromazine; Chlorprothixene; Cyclic AMP; Desipramine; Haloperidol; Imipramine; Male; Phosphoric Diester Hydrolases; Rats; Theophylline; Tranquilizing Agents; Triflupromazine; Tritium | 1973 |
Proceedings: Thiamine metabolism in the central nervous system. 2. Effects of psychotropic drugs on rat brain thiamine di- and tri-phosphatase.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Imipramine; Phosphoric Monoester Hydrolases; Rats; Thiamine | 1974 |
Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.
Topics: Adenosine Diphosphate; Amitriptyline; Antidepressive Agents; Blood Glucose; Blood Platelets; Bucladesine; Carbon Radioisotopes; Chlorpromazine; Cyproheptadine; Desipramine; Epinephrine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Nortriptyline; Platelet Adhesiveness; Promethazine; Serotonin; Thrombin | 1974 |
Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.
Topics: 1-Propanol; Adenosine Diphosphate; Adenosine Monophosphate; Aminophylline; Blood Platelets; Caffeine; Chlorpromazine; Cyclic AMP; Desipramine; Dibenzothiepins; Epinephrine; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Piperazines; Platelet Adhesiveness | 1974 |
In vivo inhibition of 3H-noradrenaline uptake by mouse brain slices in vitro.
Topics: Amitriptyline; Amphetamine; Animals; Brain; Chlordiazepoxide; Chlorpromazine; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Norepinephrine; Tritium | 1966 |
Accumulation of alpha-methyltyramine by the noradrenaline uptake process in the isolated rat heart.
Topics: Animals; Chlorpromazine; Cocaine; Desipramine; In Vitro Techniques; Metaraminol; Myocardium; Norepinephrine; Perfusion; Phenoxybenzamine; Rats; Tritium; Tyramine | 1966 |
Ionization constants and water solubilities of some aminoalkylphenothiazine tranquillizers and related compounds.
Topics: Amitriptyline; Chemical Phenomena; Chemistry; Chlorpromazine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Solubility; Thioridazine; Tranquilizing Agents; Trifluoperazine; Water | 1967 |
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine | 1967 |
Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action.
Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Central Nervous System Stimulants; Chlorpromazine; Cocaine; Depression; Desipramine; Emotions; Humans; Imipramine; Lithium; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Rats; Reserpine; Tranquilizing Agents; Tritium | 1967 |
Effect of desipramine on the depolarized isolated renal artery.
Topics: Animals; Calcium; Chlorpromazine; Cocaine; Desipramine; Electrophysiology; Muscle Contraction; Phenoxybenzamine; Phentolamine; Potassium; Rats; Renal Artery | 1967 |
On the specificity of the reversal of reserpine hypothermia for the evaluation of antiderpressant effect.
Topics: Animals; Antidepressive Agents; Aspirin; Body Temperature; Chlorpromazine; Desipramine; Female; Rats; Reserpine | 1968 |
[On the continuous retinal activity].
Topics: Action Potentials; Animals; Antidepressive Agents; Cats; Central Nervous System Stimulants; Chlorpromazine; Desipramine; Electrodes; Electrophysiology; Light; Neurons; Optic Nerve; Picrotoxin; Retina; Strychnine; Temperature; Tranquilizing Agents | 1968 |
Metabolic effects induced by the interaction of reserpine with desipramine.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Body Temperature; Chlorpromazine; Desipramine; Fatty Acids, Nonesterified; Female; Glycogen; Hypothermia; Lactates; Liver Glycogen; Rats; Reserpine | 1968 |
Evidence of catecholamine mediation in the "aberrant" behaviour induced by lysergic acid diethylamide (LSD) in the rat.
Topics: Animals; Behavior, Animal; Catecholamines; Chlorpromazine; Desipramine; Dibenzylchlorethamine; Disulfiram; Dopamine; Ethanolamines; Locomotion; Lysergic Acid Diethylamide; Male; Methysergide; Perphenazine; Phenoxybenzamine; Phenylalanine; Propranolol; Rats; Reserpine; Serotonin | 1968 |
Influence of some drugs on chlorpromazine-induced adrenaline release.
Topics: Adrenal Medulla; Anesthetics, Local; Animals; Atropa belladonna; Cattle; Cell Membrane; Chlorpromazine; Curare; Desipramine; Epinephrine; Female; Guanethidine; Heparin; Hexamethonium Compounds; Histamine H1 Antagonists; In Vitro Techniques; Ouabain; Phenelzine; Plants, Medicinal; Plants, Toxic; Pyrogallol; Spectrophotometry; Sympatholytics; Time Factors | 1968 |
The effects of some centrally acting drugs on the glucocorticoid induction of hepatic tyrosine transaminase.
Topics: Adrenalectomy; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Desipramine; Diphenhydramine; Enzyme Induction; Female; Fluocinolone Acetonide; Fluorometholone; Glucocorticoids; Hydrocortisone; Imipramine; Liver; Male; Prednisone; Proadifen; Promazine; Promethazine; Rats; Reserpine; Sex Factors; Triflupromazine; Tyrosine Transaminase | 1969 |
Glycine uptake in rat central nervous system slices and homogenates: evidence for different uptake systems in spinal cord and cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport, Active; Carbon Isotopes; Cerebellum; Cerebral Cortex; Chlorpromazine; Chromatography, Paper; Desipramine; Ethylmaleimide; Glycine; Hydrazines; Imipramine; Medulla Oblongata; Mesencephalon; Neurotransmitter Agents; Pons; Rats; Spinal Cord; Synaptic Vesicles; Tritium | 1971 |
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts | 1972 |
Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man.
Topics: Amphetamine; Animals; Chlorpromazine; Desipramine; Drug Interactions; Histamine; Hydrazines; Hydrocortisone; Imipramine; Iproniazid; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nialamide; Opipramol; Phenothiazines; Phenylhydrazines; Prednisolone; Proadifen; Promazine; Rats; Transferases | 1972 |
Effect of central stimulants and depressants on mouse brain acetylcholine and choline levels.
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Brain Chemistry; Central Nervous System Stimulants; Chlorpromazine; Choline; Depression, Chemical; Desipramine; Diazepam; Haloperidol; Ketones; Male; Mice; Pentobarbital; Pentylenetetrazole; Physostigmine; Reserpine; Stimulation, Chemical; Tranquilizing Agents; Tremorine | 1972 |
[Tricyclic anti-depressant drugs and dopamine sensitive adenylcyclase from rat caudate nuclei].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Basal Metabolism; Caudate Nucleus; Chlorpromazine; Desipramine; Dopamine; Imipramine; Nortriptyline; Rats; Stimulation, Chemical | 1974 |
[Changes in the cellular efflux of catecholamines due to neuroleptics and tricyclic antidepressants].
Topics: Animals; Brain; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Dopamine; Male; Microscopy, Fluorescence; Nialamide; Rats; Time Factors | 1974 |
[Analysis of the monoaminergic mechanisms of the dorsal hippocampus actualizing conditioned avoidance reactions in rats].
Topics: Animals; Avoidance Learning; Chlorpromazine; Conditioning, Classical; Depression, Chemical; Desipramine; Dihydroergotamine; Dopamine; Drug Interactions; Haloperidol; Hippocampus; Imipramine; Male; Motor Activity; Muscle Tonus; Norepinephrine; Perphenazine; Phentolamine; Rats; Reaction Time; Serotonin | 1974 |
Pharmacokinetic interaction between neuroleptics and tricyclic antidepressants in the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Feces; Glucuronates; Heart; Imipramine; Injections, Intraperitoneal; Male; Nortriptyline; Perphenazine; Rats | 1974 |
A possible mechanism for the antischizophrenic action of chlorpromazine: inhibition of the formation of dimethyltryptamine by chlorpromazine metabolites.
Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Hallucinogens; Humans; Imipramine; In Vitro Techniques; Indoles; Lung; Mass Spectrometry; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Schizophrenia; Serotonin; Solvents; Tetrahydrofolates; Time Factors; Tryptamines | 1974 |
Drug-induced changes of 5-hydroxyindoles in central nervous system in the rats.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chlorpromazine; Desipramine; Female; Hydroxyindoleacetic Acid; Imipramine; Indoles; Iproniazid; Male; Rats; Reserpine; Serotonin | 1973 |
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature | 1974 |
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins.
Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl | 1974 |
The role of catecholamines in the reversal of reserpine-induced hypothermia in mice by desipramine and chlorpromazine.
Topics: Animals; Body Temperature; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Reserpine; Thiocarbamates | 1972 |
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents | 1972 |
Noradrenaline uptake mechanisms in human atrium.
Topics: Adolescent; Adult; Animals; Binding Sites; Cell Membrane; Chlorpromazine; Desipramine; Dibenzazepines; Drug Interactions; Humans; Hydroxydopamines; Imipramine; Metaraminol; Middle Aged; Myocardium; Nialamide; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Drug; Reserpine; Sorbitol; Tritium | 1972 |
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine | 1973 |
Central antisecretory action of desmethylimipramine in the rat.
Topics: Animals; Central Nervous System; Chlorpromazine; Desipramine; Gastric Juice; Gastric Mucosa; Imipramine; Injections, Intravenous; Male; Morphine; Rats; Stomach | 1973 |
Mind and body in biological psychiatry.
Topics: Adult; Affect; Carbon Dioxide; Chlorpromazine; Conditioning, Classical; Depression; Desipramine; Erectile Dysfunction; Extinction, Psychological; Female; Galvanic Skin Response; Humans; Hypnosis; Lysergic Acid Diethylamide; Male; Mental Disorders; Middle Aged; Psychiatry; Psychophysiologic Disorders; Psychophysiology; Stress, Psychological | 1973 |
Acute effects of 6-hydroxydopa on central monoaminergic neurons.
Topics: Alcohols; Amphetamine; Animals; Autonomic Nervous System; Brain Chemistry; Catecholamines; Chlorpromazine; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Hydroxydopamines; Male; Mice; Neurons; Norepinephrine; Time Factors; Tranylcypromine | 1973 |
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium | 1973 |
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium | 1973 |
The effect of pheniramine and its structural analogues on 5-hydroxytryptamine in rat and mouse brain.
Topics: Amines; Amphetamine; Animals; Biological Transport; Brompheniramine; Chlorine; Chlorpheniramine; Chlorpromazine; Corpus Striatum; Desipramine; Fluorine; Hydroxyindoleacetic Acid; Male; Mice; Pheniramine; Promethazine; Rats; Serotonin; Structure-Activity Relationship; Synaptosomes; Time Factors | 1973 |
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine | 1973 |
The influence of psychotropic drugs on prostaglandin biosynthesis.
Topics: Animals; Antidepressive Agents; Aspirin; Carbon Radioisotopes; Cell-Free System; Chlorpromazine; Chromatography, Thin Layer; Depression, Chemical; Desipramine; Doxepin; Guinea Pigs; Indomethacin; Lung; Methods; Pargyline; Phenelzine; Promazine; Prostaglandins; Tranylcypromine | 1974 |
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction.
Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors | 1974 |
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors | 1974 |
Imipramine and chlorpromazine in hepatic microsomal systems.
Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Cobalt; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hydroxylation; Imipramine; In Vitro Techniques; Kinetics; Male; Methylphenidate; Microsomes, Liver; Phenobarbital; Proadifen; Proteins; Spectrophotometry, Ultraviolet | 1974 |
Pharmacokinetics of chlorpromazine metabolites--a colossal problem.
Topics: Animals; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Dansyl Compounds; Desipramine; Drug Stability; Fluorometry; Hydroxylation; Kinetics; Methods; Sheep; Solvents; Time Factors | 1974 |
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase | 1974 |
Suppression of hippocampal DFP discharges by chlorpromazine, imipramine and desipramine.
Topics: Animals; Cats; Chlorpromazine; Depression, Chemical; Desipramine; Drug Antagonism; Hippocampus; Imipramine; Isoflurophate; Male; Membrane Potentials; Stereotaxic Techniques | 1971 |
Release in vitro of 5-hydroxytryptamine from spindle cells of the domestic fowl.
Topics: Amphetamine; Animals; Blood Cell Count; Blood Platelets; Blood Proteins; Chickens; Chlorpromazine; Desipramine; Edetic Acid; Potassium; Serotonin; Time Factors; Tryptamines; Tyramine | 1970 |
[Binding to human serum proteins of drugs belonging to phenothiazine series, iminodibenzyle, thioxanthene and thiophenylpyridylamine].
Topics: Antidepressive Agents; Blood Proteins; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Chromatography, Gel; Desipramine; Dibenzazepines; Humans; Imipramine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Protein Binding; Spectrophotometry; Thiazines; Trimeprazine | 1971 |
Blocking H 3 -Norepinephrine uptake and some guanethidine-induced effects with tricyclic psychotherapeutic drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Autonomic Fibers, Postganglionic; Benzofurans; Blood Pressure; Cats; Chlorpromazine; Desipramine; Dibenzoxepins; Electric Stimulation; Guanethidine; Heart; Imipramine; Male; Methylamines; Myocardium; Nictitating Membrane; Norepinephrine; Rats; Rats, Inbred Strains; Thioridazine; Tranquilizing Agents; Tritium | 1972 |
Studies on the accumulation of O-methylated dopamine and noradrenaline in the rat brain following various neuroleptics, thymoleptics and aceperone.
Topics: Acetamides; Animals; Antidepressive Agents; Benzimidazoles; Brain; Brain Chemistry; Butyrophenones; Chlorpromazine; Chlorprothixene; Desipramine; Dopamine; Imipramine; Ketones; Male; Methylation; Norepinephrine; Normetanephrine; Pargyline; Piperidines; Rats; Stimulation, Chemical; Tranquilizing Agents; Tyramine | 1972 |
Study of the mechanisms of action of desipramine and chlorpromazine in reversing reserpine-induced hypothermia in mice.
Topics: Adrenalectomy; Animals; Chlorisondamine; Chlorpromazine; Desipramine; Hypothermia; Male; Mice; Reserpine | 1972 |
The effect of amantadine on motor activity and catalepsy in rats.
Topics: Amantadine; Animals; Brain; Catalepsy; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Male; Methyltyrosines; Motor Activity; Nialamide; Rats; Rats, Inbred Strains; Reserpine; Spiro Compounds; Thiocarbamates | 1972 |
Detection of some psychotherapeutic drugs and their metabolites in urine.
Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1971 |
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors.
Topics: Aminobutyrates; Animals; Caproates; Carnitine; Centrifugation, Density Gradient; Cerebellum; Cerebral Cortex; Chlorpromazine; Cysteamine; Desipramine; Dithiothreitol; Ethylmaleimide; Haloperidol; Hippocampus; Imipramine; Ornithine; Pimelic Acids; Propionates; Rats; Spinal Cord; Sulfanilamides; Synaptic Vesicles; Taurine; Tritium; Valerates | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
Possible involvement of glycogen phosphorylase of brain in the affective states.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorpromazine; Depression; Desipramine; Drug Interactions; Female; Humans; Iproniazid; Pargyline; Phenothiazines; Phosphorylases; Prochlorperazine; Promazine; Promethazine; Rats; Receptors, Adrenergic; Reserpine; Stereoisomerism; Tranquilizing Agents | 1971 |
Effect of chlorpromazine, desmethylimipramine and lithium on dopamine uptake in the rat pancreas.
Topics: Animals; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Lithium; Pancreas; Rats | 1971 |
5-hydroxytryptamine uptake by rat brain in vitro.
Topics: 5-Hydroxytryptophan; Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Dinitrophenols; Dopamine; Glucose; Imipramine; In Vitro Techniques; Iodoacetates; Iproniazid; Male; Norepinephrine; Ouabain; Rats; Reserpine; Serotonin; Serotonin Antagonists; Tryptamines | 1967 |
A possible relationship between catecholamines and acute toxicity of desipramine.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine | 1968 |
Effect of psychotherapeutic drugs on hyperemotionality of rats in which the olfactory bulb was removed.
Topics: Amitriptyline; Animals; Benperidol; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Desipramine; Emotions; Imipramine; Limbic System; Male; Meprobamate; Phenobarbital; Rats; Reserpine; Tranquilizing Agents | 1967 |
Central muscle relaxant activity of a dozen CNS active agents and a correlation with their psychotropic activity.
Topics: Amphetamine; Animals; Antidepressive Agents; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Desipramine; Dibenzothiazepines; Ephedrine; Female; Imipramine; Iproniazid; Male; Mephenesin; Monoamine Oxidase Inhibitors; Muscles; Orphenadrine; Phenelzine; Reflex; Thioridazine; Tranquilizing Agents | 1968 |
Synergism of imipramine and desmethylimipramine with reserpine in the frog. Interaction with 5-hydroxytryptophan and 2-bromolysergid diethylamide (BOL-148).
Topics: 5-Hydroxytryptophan; Animals; Anura; Brain Chemistry; Chlorpromazine; Desipramine; Drug Synergism; Epinephrine; Imipramine; Lysergic Acid Diethylamide; Norepinephrine; Rats; Reserpine | 1968 |
Effect of drugs on the hemolysis of rat erythrocytes.
Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Desoxycorticosterone; Digitalis Glycosides; Diuretics; Erythrocytes; Glucose; Guanethidine; Hemolysis; Hydrocortisone; Hypotonic Solutions; Indomethacin; Levorphanol; Male; Neostigmine; Rats; Tripelennamine | 1969 |
Pharmacological effects of imipramine and desmethylimipramine in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Blepharoptosis; Brain Chemistry; Chlorpromazine; Desipramine; Diarrhea; Female; Hypnotics and Sedatives; Hypothermia, Induced; Imipramine; Male; Motor Activity; Norepinephrine; Quinolizines; Rats; Reserpine | 1969 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology | 1969 |
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine | 1969 |
The exploratory behaviour in normal and aggressive mice.
Topics: Aggression; Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Desipramine; Exploratory Behavior; Humans; Male; Mice; Pentobarbital | 1969 |
[Effect of thymoleptics on acid production of the stomach. Preliminary report].
Topics: Amitriptyline; Chlorpromazine; Depression; Depression, Chemical; Desipramine; Dibenzazepines; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Humans; Imipramine; Methotrimeprazine; Stomach; Tranquilizing Agents | 1969 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
Effects of psychotherapeutic drugs on hypothalamic- induced hissing in cats.
Topics: Amitriptyline; Animals; Cats; Chlordiazepoxide; Chlorpromazine; Desipramine; Electric Stimulation; Female; Hypothalamus; Imipramine; Injections, Intraperitoneal; Male; Pentobarbital; Perphenazine; Tranquilizing Agents; Trifluoperazine; Vocalization, Animal | 1970 |
Effects of hallucinogenic and other drugs on the nest-building behaviour of mice.
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Competitive Behavior; Depression, Chemical; Desipramine; Dextroamphetamine; Gossypium; Hallucinogens; Mescaline; Mice; Nesting Behavior; Phenethylamines; Tremor | 1970 |
Studies indicating a central antisecretory site of action for desmethylimipramine (DMI).
Topics: Animals; Carbachol; Chlorpromazine; Desipramine; Dogs; Electric Stimulation; Female; Fistula; Gastric Acidity Determination; Gastric Juice; Hexamethonium Compounds; Hexoses; Male; Propantheline; Rats; Stomach; Vagus Nerve | 1970 |
Blockade of norepinephrine uptake and related activities of cis- and trans-N,N'-bis-(1-naphthylmethyl)-1,4-cyclohexane bis-(methylamine) dihydrochloride.
Topics: Adipose Tissue; Amines; Animals; Atropine; Chlorpromazine; Cyclohexanes; Desipramine; Drug Antagonism; Epididymis; Eyelids; Female; Hypnotics and Sedatives; Imipramine; Lacrimal Apparatus; Lipid Mobilization; Male; Mathematics; Metaraminol; Methyltyrosines; Mice; Motor Activity; Muscles; Myocardium; Naphthalenes; Norepinephrine; Rats; Species Specificity; Stereoisomerism; Tetrabenazine; Time Factors; Tremor; Tremorine; Tritium | 1970 |
Influence of iminodibencylic derivatives on the evoked potentials in the dorsal hippocampus of the rat.
Topics: Animals; Chlorpromazine; Depression, Chemical; Desipramine; Evoked Potentials; Hippocampus; Imipramine; Male; Rats; Stimulation, Chemical | 1970 |
Depletion of brain noradrenaline and dopamine by 6-hydroxydopamine.
Topics: Amphetamine; Animals; Animals, Newborn; Brain Chemistry; Chlorpromazine; Desipramine; Dopamine; Imipramine; Male; Metaraminol; Mixed Function Oxygenases; Neurons; Norepinephrine; Pargyline; Phenethylamines; Rats; Reserpine; Sodium Chloride; Tritium; Tyrosine | 1971 |
Reversal of reserpine-induced hypothermia by pharmacological agents other than antidepressants.
Topics: Animals; Antidepressive Agents; Aspirin; Body Temperature; Chlorpromazine; Depression, Chemical; Desipramine; Male; Mice; Morphine; Phenoxybenzamine; Propranolol; Reserpine; Sympatholytics | 1967 |
Inhibition by drugs of the accumulation in vitro of 5-hydroxytryptamine in guinea-pig vas deferens.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guinea Pigs; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Serotonin; Vas Deferens | 1968 |
Inhibition of the metabolism of H3-melatonin by phenothiazines.
Topics: Amphetamine; Animals; Antimetabolites; Body Temperature; Brain; Chlorpromazine; Depression, Chemical; Desipramine; Female; Imipramine; Liver; Melatonin; Phenobarbital; Phenothiazines; Promazine; Promethazine; Rats; Tritium | 1968 |
Influence of drugs on catecholamine metabolism in brain as studied by 14C-tyrosine.
Topics: Animals; Brain; Carbon Isotopes; Catecholamines; Chlorpromazine; Desipramine; Dopamine; Haloperidol; Mice; Norepinephrine; Promethazine; Rats; Stimulation, Chemical; Tyrosine | 1968 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents | 1968 |
Accumulation and disappearance of catecholamines formed from tyrosine-14C in mouse brain; effect of some psychotropic drugs.
Topics: Animals; Brain Chemistry; Carbon Isotopes; Catecholamines; Chlorpromazine; Desipramine; Dopamine; Haloperidol; Injections, Intravenous; Mice; Norepinephrine; Promethazine; Tyrosine | 1968 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1968 |
Release of [3H]serotonin from brain slices.
Topics: Animals; Brain; Calcium; Carbon Isotopes; Centrifugation; Chlorpromazine; Desipramine; Duodenum; Electric Stimulation; Hydroxyindoleacetic Acid; In Vitro Techniques; Lithium; Liver; Lysergic Acid Diethylamide; Nerve Endings; Ouabain; Rats; Salivary Glands; Serotonin; Spectrum Analysis; Tritium | 1969 |
Some observations on the adrenergic blocking activity of desipramine and amitriptyline on aortic strips of rabbits.
Topics: Amitriptyline; Animals; Aorta; Calcium; Chlorpromazine; Desipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rabbits; Receptors, Drug | 1969 |
Effects of psychoactive drugs on the metabolism of intracisternally administered serotonin in rat brain.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Cerebellum; Chlorpromazine; Desipramine; Ethers; Hypothalamus; Imipramine; Lysergic Acid Diethylamide; Medulla Oblongata; Mesencephalon; Norepinephrine; Pargyline; Pentobarbital; Pons; Rats; Reserpine; Serotonin; Tritium | 1969 |
[The influence of psychopharmacologic agents on the acitvity of retinal neurons].
Topics: Action Potentials; Amitriptyline; Animals; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Neurons; Optic Nerve; Retina; Tranquilizing Agents | 1969 |
[The influence of psychopharmacologic agents on visual evoked potentials in the cat].
Topics: Amitriptyline; Animals; Cats; Cerebral Cortex; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Evoked Potentials; Haloperidol; Tranquilizing Agents; Vision, Ocular; Visual Cortex | 1969 |
A method for recording the effect of drugs on the activity of small mammals over long periods of time.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Desipramine; Hexobarbital; Hypnotics and Sedatives; Imipramine; Iproniazid; Meprobamate; Mice; Reserpine | 1966 |
Influence of various agonists and antagonists on the release of free fatty acids from adipose tissue in vitro.
Topics: Adipose Tissue; Animals; Chlorpromazine; Desipramine; Dextroamphetamine; Dopamine; Epididymis; Epinephrine; Fatty Acids; Imipramine; Isoproterenol; Male; Norepinephrine; Rats; Tyramine | 1966 |
The effect of drugs on the release of norepinephrine-H from central nervous system tissued by electrical stimulation in vitro.
Topics: Animals; Brain; Brain Chemistry; Brain Stem; Calcium; Cerebral Cortex; Chlorpromazine; Denervation; Desipramine; Dopamine; Electric Stimulation; Heart Atria; Liver; Male; Myocardium; Norepinephrine; Rats; Salivary Glands; Thiopental; Tritium | 1967 |
Hypoglycemia, stress and growth hormone release: blockade of growth hormone release by drugs acting on the central nervous system.
Topics: Animals; Bethanechol Compounds; Blood Glucose; Chlorpromazine; Cold Temperature; Desipramine; Dexamethasone; Dextroamphetamine; Epinephrine; Growth Hormone; Indoles; Insulin; Iproniazid; Morphine; Pentobarbital; Pituitary Gland; Rats; Reserpine; Vasopressins | 1967 |
The effects of psychoactive drugs on norepinephrine-3-H metabolism in brain.
Topics: Animals; Brain; Brain Chemistry; Chlorpromazine; Desipramine; Imipramine; Lithium; Norepinephrine; Normetanephrine; Rats | 1967 |
Central nervous system activity of 1-(3-methoxypropylamino)-2-hydroxy-2-(1,4-benzodioxan-2-yl)-ethane hydrochloride.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Desipramine; Drug Synergism; Electroencephalography; Humans; Methamphetamine; Phenelzine; Rats; Reserpine; Reticular Formation; Sympatholytics; Thiopental | 1967 |
[The potentiating and antagonistic effects of desipramine and chlorpromazine on reserpine-produced symptoms in mice].
Topics: Animals; Chlorpromazine; Desipramine; Drug Antagonism; Drug Synergism; Mice; Reserpine | 1967 |
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine | 1980 |
Noradrenaline uptake by synaptosomes and (Na+-K+) ATPase.
Topics: Animals; Brain; Chlorpromazine; Desipramine; In Vitro Techniques; Kinetics; Magnesium; Neurotransmitter Agents; Norepinephrine; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Synaptosomes; Time Factors | 1980 |
Binding of phenothiazine neuroleptics to plasma proteins.
Topics: Antipsychotic Agents; Blood Proteins; Chlorpromazine; Desipramine; Humans; Kinetics; Perphenazine; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Structure-Activity Relationship; Trifluoperazine; Tritium | 1983 |
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride | 1984 |
Temperature dependence of the interaction of lipophilic drugs with (Na+ + K+)-ATPase from pig kidney [proceedings].
Topics: 4-Nitrophenylphosphatase; Animals; Chlorpromazine; Desipramine; Kidney; Kinetics; Sodium-Potassium-Exchanging ATPase; Swine; Tetracaine | 1980 |
Effects of phenothiazines and dibenzazepines on axonal transport and microtubule assembly in vitro.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Chlorpromazine; Desipramine; Dibenzazepines; Lofepramine; Microtubules; Phenothiazines; Phosphocreatine; Rana pipiens; Rana temporaria; Sciatic Nerve; Thioridazine; Trifluoperazine | 1982 |
Pre- and postsynaptic adrenergic activation by norepinephrine reuptake inhibitors in the field-stimulated rat vas deferens.
Topics: Amitriptyline; Animals; Chlorpromazine; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Protriptyline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1981 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
On the role of brain alpha-adrenergic systems in the production of paradoxical sleep.
Topics: Animals; Chlorpromazine; Clonidine; Desipramine; Male; Phenoxybenzamine; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Secologanin Tryptamine Alkaloids; Sleep, REM | 1982 |
Effect of age and sex on the plasma binding of acidic and basic drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Proteins; Chlorpromazine; Desipramine; Female; Humans; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenytoin; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Sex Factors | 1984 |
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; Desipramine; Diazepam; Humans; Injections; Male; Microinjections; Olfactory Bulb; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats.
Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Brain; Chlorpromazine; Desipramine; Doxepin; Gastric Acid; Male; Pirenzepine; Rats; Rats, Inbred Strains | 1984 |
Effects of catecholamine agonist and antagonist drugs on acute stomach ulceration induced by medial hypothalamic lesions in rats.
Topics: Amphetamine; Animals; Catecholamines; Chlorpromazine; Clozapine; Desipramine; Haloperidol; Hypothalamus, Middle; Isoproterenol; Male; Pargyline; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stomach Ulcer | 1983 |
The locus coeruleus: actions of psychoactive drugs.
Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine | 1983 |
A study on the effects of chlorpromazine and desipramine on rat adrenal steroidogenesis and cholesterol esterase activity.
Topics: Adrenal Glands; Animals; Carboxylic Ester Hydrolases; Chlorpromazine; Corticosterone; Desipramine; Male; Rats; Rats, Inbred Strains; Sterol Esterase | 1983 |
Effect of psychotrophic drugs on [14C]tryptophan metabolism in cultured rat pineal gland.
Topics: Animals; Cells, Cultured; Chlorpromazine; Desipramine; Haloperidol; Male; Melatonin; Norepinephrine; Phenothiazines; Pineal Gland; Psychotropic Drugs; Rats; Serotonin; Tryptophan | 1983 |
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro.
Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature | 1980 |
A study on the effect of chlorpromazine and desipramine on the activity of some adrenal enzymes.
Topics: Adrenal Glands; Animals; Chlorpromazine; Desipramine; Isocitrate Dehydrogenase; Malate Dehydrogenase; Rats; Succinate Dehydrogenase | 1981 |
Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides.
Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Cyproheptadine; Desipramine; Diminazene; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Melarsoprol; Suramin; Trypanocidal Agents; Trypanosoma; Verapamil | 1996 |
Dual-label time-resolved fluoroimmunoassay of psychopharmaceuticals and stimulants in serum.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Calibration; Central Nervous System Stimulants; Chlorpromazine; Desipramine; Fluoroimmunoassay; Methamphetamine; Rabbits; Sensitivity and Specificity; Substance Abuse Detection; Toxicology | 2000 |
Chronic treatment of C6 glioma cells with antidepressant drugs results in a redistribution of Gsalpha.
Topics: Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Fluoxetine; Glioma; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Rats; Subcellular Fractions; Tumor Cells, Cultured | 2001 |
INFLUENCE OF IMIPRAMINE AND RELATED PSYCHOACTIVE AGENTS ON THE EFFECT OF 5-HYDROXYTRYPTAMINE AND CATECHOLAMINES ON THE CAT NICTITATING MEMBRANE.
Topics: Amitriptyline; Animals; Antidepressive Agents; Catecholamines; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Epinephrine; Imipramine; Nictitating Membrane; Norepinephrine; Pharmacology; Promazine; Psychotropic Drugs; Research; Serotonin; Tranquilizing Agents | 1963 |
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive Disorder; Depressive Disorder, Major; Desipramine; Humans; Imipramine; Psychotic Disorders; Schizophrenia | 1963 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
[COMPARATIVE PHARMACOLOGICAL INVESTIGATIONS WITH TOFRANIL, PERTOFRAN AND INSIDON].
Topics: Acetylcholine; Amphetamine; Amphetamines; Anesthetics; Animals; Antidepressive Agents; Catatonia; Cats; Chlorpromazine; Cricetinae; Desipramine; Dextroamphetamine; Epinephrine; Ethanol; Guinea Pigs; Hexobarbital; Histamine; Imipramine; Mice; Neuromuscular Junction; Norepinephrine; Opipramol; Orientation; Pharmacology; Rats; Research; Reserpine; Serotonin; Tetrabenazine; Tremor; Tyramine | 1964 |
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine | 1964 |
EFFECT OF CENTRALLY-ACTING DRUGS ON MOBILIZATION OF FREE FATTY ACIDS.
Topics: Central Nervous System Agents; Chlorpromazine; Desipramine; Fatty Acids; Fatty Acids, Nonesterified; Hallucinogens; Imipramine; Indoles; Lipid Metabolism; Lipids; Lysergic Acid Diethylamide; Mescaline; Pharmacology; Psilocybin; Reserpine; Thioridazine; Tranquilizing Agents | 1964 |
EFFECT OF IMIPRAMINE AND SOME ANALOGUES ON THE UPTAKE OF 5-HYDROXYTRYPTAMINE BY HUMAN BLOOD PLATELETS IN VITRO.
Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Chlorpromazine; Desipramine; Humans; Imipramine; In Vitro Techniques; Metabolism; Orphenadrine; Pharmacology; Research; Serotonin | 1964 |
FATAL HYPERPYREXIA WITH ANTIDEPRESSANT DRUGS.
Topics: Antidepressive Agents; Chlorpromazine; Desipramine; Fever; Mortality; Phenelzine; Toxicology | 1964 |
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervous System; Bradycardia; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Desipramine; Dogs; Epinephrine; Imipramine; Mice; Norepinephrine; Pharmacology; Promazine; Rats; Research; Reserpine; Sleep; Toxicology; Tranquilizing Agents; Vasomotor System; Yohimbine | 1964 |
INHIBITION OF NORADRENALINE UPTAKE BY DRUGS.
Topics: Bretylium Compounds; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guanethidine; Heart; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Pharmacology; Rats; Research; Reserpine; Sympatholytics | 1965 |
POTENTIATION OF NOREPINEPHRINE IN THE ISOLATED VAS DEFERENS OF THE RAT BY SOME CNS STIMULANTS AND ANTIDEPRESSANTS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Humans; Imipramine; Male; Methylphenidate; Norepinephrine; Pharmacology; Phenmetrazine; Piperidines; Rats; Research; Tranquilizing Agents; Vas Deferens | 1965 |
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents | 1964 |
ON THE MEMBRANE EFFECTS OF CHLORPROMAZINE: UPTAKE OF BIOLOGIC AMINES BY THE BLOOD PLATELET AND RED CELL.
Topics: Amines; Antimetabolites; Biological Products; Biological Transport; Blood Platelets; Carbon Isotopes; Cell Membrane Permeability; Chlorpromazine; Cocaine; Desipramine; Erythrocytes; Ethylmaleimide; Hallucinogens; Humans; Norepinephrine; Pyrroles; Radiometry; Research; Reserpine; Serotonin | 1964 |
Antidepressant drug treatment induces Arc gene expression in the rat brain.
Topics: Animals; Antidepressive Agents; Brain; Chlorpromazine; Cyclohexanols; Cytoskeletal Proteins; Desipramine; Gene Expression; Male; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Neuronal Plasticity; Paroxetine; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Tranylcypromine; Up-Regulation; Venlafaxine Hydrochloride | 2003 |
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Atomoxetine Hydrochloride; Brain; Chlorpromazine; Citalopram; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2017 |
Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
Topics: Cell Membrane Permeability; Chlorpromazine; Desipramine; Domperidone; Kinetics; Labetalol; Lipid Bilayers; Loperamide; Molecular Dynamics Simulation; Molecular Structure; Propranolol; Thermodynamics; Verapamil | 2018 |