chlorpromazine and debrisoquin

chlorpromazine has been researched along with debrisoquin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Benitez, J; Calandra, S; Campo, GM; Caputi, AP; Carrillo, JA; Spina, E1
Tang, SW1
Benitez, J; Buemi, AL; Caputi, AP; Cobaleda, J; Garcia, MA; Llerena, A; Piña, B; Spina, E1
Bounameaux, Y1
Cooper, JK; Hawes, EM; Korchinski, ED; Midha, KK; Muralidharan, G1

Reviews

1 review(s) available for chlorpromazine and debrisoquin

ArticleYear
Relevance of polymorphic drug oxidation in the use of neuroleptics in schizophrenia.
    Progress in clinical and biological research, 1986, Volume: 214

    Topics: Amoxapine; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Asian People; Chlorpromazine; Debrisoquin; Humans; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Schizophrenia; White People

1986

Trials

1 trial(s) available for chlorpromazine and debrisoquin

ArticleYear
Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Depression, Chemical; Enzyme Inhibitors; Humans; Hydroxylation; Male; Mixed Function Oxygenases; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Quinidine

1996

Other Studies

6 other study(ies) available for chlorpromazine and debrisoquin

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Debrisoquine oxidation in an Italian population: a study in healthy subjects and in schizophrenic patients.
    Pharmacological research, 1992, Volume: 25, Issue:1

    Topics: Adult; Chlorpromazine; Debrisoquin; Female; Humans; Italy; Male; Middle Aged; Oxidation-Reduction; Phenotype; Schizophrenia; White People

1992
Debrisoquine oxidation in schizophrenic patients treated with neuroleptics.
    Pharmacological research communications, 1988, Volume: 20, Issue:12

    Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Debrisoquin; Female; Humans; Hydroxylation; Isoquinolines; Male; Methotrimeprazine; Middle Aged; Oxidation-Reduction; Schizophrenia; Thioridazine

1988
[Studies on the effect of various substances on platelet function with several methods].
    Die Medizinische Welt, 1973, Feb-02, Volume: 24, Issue:5

    Topics: Amphetamine; Anti-Anxiety Agents; Blood Platelets; Caffeine; Chlorpromazine; Debrisoquin; Dibenzazepines; Flurazepam; Guanethidine; Humans; Oxazoles; Papaverine; Phenytoin; Platelet Aggregation; Pyridines; Theophylline

1973