chlorpromazine has been researched along with dactinomycin in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Amory, C; Bousquet, B; Mainard, F | 1 |
| Campbell, RM; Scanes, CG | 1 |
| Bertini, R; Bianchi, M; Ghezzi, P; Mengozzi, M | 1 |
| Olenev, SN | 1 |
| Colson, SH; Maris, WS; Tolson, WW | 1 |
| Dube, DK; Dutta, HN; Ghosh, JJ; Pal, B | 1 |
| Roberts, RJ | 1 |
| Dybing, E | 1 |
| Garry, VF; Moore, RD | 1 |
| Burkard, WP; Gey, KF | 1 |
| Ebadi, MS | 1 |
| Plaa, GL; Roberts, RJ | 1 |
| BUTLER, WT; COONS, AH | 1 |
1 review(s) available for chlorpromazine and dactinomycin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
18 other study(ies) available for chlorpromazine and dactinomycin
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
[Mechanism of induction of tyrosine in rat liver by phenothiazine derivatives and related chemical compounds].
Topics: Adrenal Glands; Adrenalectomy; Animals; Chlorpromazine; Dactinomycin; Drug Combinations; Drug Synergism; Enzyme Induction; Hydrocortisone; Liver; Phenothiazines; Promethazine; Rats; Tyrosine Transaminase | 1978 |
Pharmacological investigations on the lipolytic and antilipolytic effects of growth hormone (GH) in chicken adipose tissue in vitro: evidence for involvement of calcium and polyamines.
Topics: Adipose Tissue; Animals; Calcimycin; Calcium; Chickens; Chlorpromazine; Cycloheximide; Dactinomycin; Eflornithine; Growth Hormone; Lipolysis; Male; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Synthesis Inhibitors; RNA; Spermidine; Verapamil | 1988 |
Protective effect of chlorpromazine against the lethality of interleukin 1 in adrenalectomized or actinomycin D-sensitized mice.
Topics: Adrenalectomy; Animals; Chlorpromazine; Dactinomycin; Dexamethasone; Escherichia coli; Interleukin-1; Lipopolysaccharides; Male; Mice; Tumor Necrosis Factor-alpha | 1989 |
[Doses and action of a series of pharmacologic agents on the growth of neuroblasts in culture].
Topics: Acetylcholinesterase; Acyltransferases; Adenosine Triphosphatases; Adenosine Triphosphate; Aminobutyrates; Animals; Azides; Chick Embryo; Chloramphenicol; Chlorpromazine; Cholinesterase Inhibitors; Culture Techniques; Dactinomycin; Glucose; Growth; Guanidines; Histamine; Histocytochemistry; Insulin; Methods; Monoamine Oxidase; Neurons; Parasympatholytics; Parasympathomimetics; Picrotoxin; Serotonin; Serotonin Antagonists; Sodium; Strychnine; Tryptamines; Tryptophan | 1969 |
Inhibition of casein hydrolysate induction and insulin induction of hepatic tyrosine transaminase in the rat.
Topics: Animals; Caseins; Chlorpromazine; Dactinomycin; Enzyme Induction; Female; Hydrocortisone; Imipramine; Insulin; Insulin Antagonists; Liver; Male; Promethazine; Protein Hydrolysates; Rats; Sodium Chloride; Tyrosine Transaminase | 1970 |
Effect of chlorpromazine on induction of different hepatic enzymes.
Topics: Animals; Chlorpromazine; Dactinomycin; Enzyme Induction; Hydro-Lyases; Liver; Male; Proteins; Rats; Threonine; Tryptophan Oxygenase; Tyrosine Transaminase | 1972 |
Microsomal metabolism of the hepatotoxin -naphthylisothiocyanate (ANIT) following phenobarbital, chlorpromazine or actinomycin D treatment.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Cell Fractionation; Chlorpromazine; Dactinomycin; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Thiocyanates | 1973 |
Effects of chlorpromazine and actinomycin D on uptake and incorporation of certain amino acids, hypoxanthine and thymidine in cultures of human skin epithelial cells.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Carbon Radioisotopes; Cells, Cultured; Chlorpromazine; Culture Media; Dactinomycin; Dose-Response Relationship, Drug; Epithelium; Humans; Hypoxanthines; Kinetics; Leucine; Phenylalanine; Skin; Thymidine; Time Factors | 1974 |
Use of the cytograf to determine cytotoxicity in fibroblast cell cultures.
Topics: Antineoplastic Agents; Cell Count; Cell Survival; Cells, Cultured; Chlorpromazine; Dactinomycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Fibroblasts; Humans; Lasers; Rotenone; Trypan Blue | 1974 |
Chlorpromazine-induced accumulation of pyridoxal-5'-phosphate and activation of the decarboxylase of aromatic amino acids in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Catecholamines; Chlorpromazine; Cycloheximide; Dactinomycin; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; In Vitro Techniques; Pyridoxal Phosphate; Rats; Serotonin; Time Factors; Tyrosine | 1969 |
Increase in brain pyridoxal phosphate by chlorpromazine.
Topics: Acetates; Alkaline Phosphatase; Animals; Brain; Brain Chemistry; Chlorpromazine; Cyanides; Cycloheximide; Dactinomycin; Dopa Decarboxylase; Dopamine; Enzyme Induction; Male; Oxidoreductases; Phosphotransferases; Pyridoxal Phosphate; Rats; Trifluoperazine; Urea | 1970 |
Potentiation and inhibition of alpha-naphthylisothiocyanate-induced hyperbilirubinemia and cholestasis.
Topics: Animals; Chlorpromazine; Cholestasis; Dactinomycin; Ethionine; Hyperbilirubinemia; In Vitro Techniques; Mice; Microsomes; Phenobarbital; Proadifen; Thiocyanates | 1965 |
STUDIES ON ANTIBODY PRODUCTION. XII. INHIBITION OF PRIMING BY DRUGS.
Topics: Animals; Antibody Formation; Antineoplastic Agents; Antiprotozoal Agents; Azaguanine; Chloramphenicol; Chlorpromazine; Colchicine; Dactinomycin; Edetic Acid; Hydrocortisone; Immunization; Mercaptopurine; Methotrexate; Mice; Pharmacology; Quinolines; Research; Thiotepa; Vaccination | 1964 |