chlorpromazine and colchicine

chlorpromazine has been researched along with colchicine in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199037 (59.68)18.7374
1990's1 (1.61)18.2507
2000's9 (14.52)29.6817
2010's15 (24.19)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Farasati, NA; Huang, Y; Randhawa, P1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bekemeier, H; Giessler, AJ; Vogel, E2
Norström, A1
Dorland, RB; Middlebrook, JL1
Miller, NE; Yin, JA1
Edström, A; Erkell, LJ; Hansson, HA1
Eidinger, D; Gery, I1
Fuller, GM; Poffenbarger, M1
Banerjee, D; Redman, CM1
Cann, JR; Hinman, ND1
Kuramochi, H; Takahashi, K; Takeuchi, T1
Di Stasi, AM; Minetti, M1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M1
Maccioni, RB1
Bishun, NP; Lloyd, N; Mills, J; Parke, DV; Raven, RW; Williams, DC1
Williams, JA1
Chinea, G; Oronsky, AL; Perper, RJ; Sanda, M1
Baba, A; Ishii, K; Iwata, H; Matsuda, T; Terashita, Z1
Williams, JA; Wolff, J1
Beliles, RP1
Kvarstein, B; Stormorken, H1
DePrey, C; Pisciotta, AV; Westring, DW1
Benmbarek, A; Lalaurie, M; Modat, G1
Hansson, HA; Lange, S; Lönnroth, I; Rozell, B; Tinberg, H1
Klinman, NR; Teale, JM1
Lebret, M; Rendu, F1
Rensing, L; Scholübbers, HG; Taylor, W1
Selvakumar, D; Wilfred, G1
Glebov, RN; Kaplun, AP; Kryzhanovskiĭ, GN; Maloletneva, OIu; Nikushkin, EV1
Gear, AR1
Perec, CJ; Sanz, NR; Stefano, FJ1
Brohee, D; Kennes, B; Neve, P1
Mornex, R; Rousset, B1
Christopherson, RI; Roufogalis, BD; Syed, SK1
Bobilya, DJ; Rowe, DJ1
Bebawy, M; Morris, MB; Roufogalis, BD1
PETERS, K1
GUIMARAES, JP1
DELPHAUT, J1
BUTLER, WT; COONS, AH1
Gore, E; Groothuis, GM; Olinga, P; Pennings, JL; Vatakuti, S1
Chen, H; Feng, X; Han, Z; Jia, Y; Li, X; Liu, Q; Liu, X; Tang, H; Wang, A1
Dusinska, M; Elje, E; Hesler, M; Kohl, Y; Mann, P; Mariussen, E; Rundén-Pran, E; Wagner, S1

Reviews

6 review(s) available for chlorpromazine and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Axonal transport and turnovers of neurohhypophyseal proteins in the rat.
    Annals of the New York Academy of Sciences, 1975, Feb-21, Volume: 248

    Topics: Anemia; Animals; Axonal Transport; Axons; Biological Transport; Chlorpromazine; Colchicine; Cysteine; Dehydration; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Female; Fucose; Glucosamine; Lactation; Nerve Tissue Proteins; Pituitary Gland, Posterior; Pregnancy; Rats; Sodium Chloride; Tetracaine; Thirst; Time Factors

1975
The effect of drugs on bile flow and composition. An overview.
    Drugs, 1986, Volume: 31, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid

1986
Molecular cytology of microtubules.
    Revisiones sobre biologia celular : RBC, 1986, Volume: 8

    Topics: Alkaloids; Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Cell Differentiation; Chlorpromazine; Colchicine; Cytoskeleton; Gene Expression Regulation; Griseofulvin; Guanosine Triphosphate; Humans; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Paclitaxel; Phosphorylation; Structure-Activity Relationship; Tubulin; Vinblastine

1986
Chromosome damage induced by chemicals.
    Chemico-biological interactions, 1973, Volume: 6, Issue:6

    Topics: Antineoplastic Agents; Aspirin; Benzene; Caffeine; Chloramphenicol; Chlorine; Chlorpromazine; Chromosome Aberrations; Chromosomes; Colchicine; Contraceptives, Oral; Cyclamates; Diazepam; Dibenzazepines; Drug Evaluation; Ethanol; Humans; Hydroxylamines; Lithium; Lymphocyte Culture Test, Mixed; Lysergic Acid Diethylamide; Nicotine; Organophosphorus Compounds; Ozone; Pesticides; Phenylbutazone

1973
The role of microtubles and microfilaments in thyroid secretion.
    Recent progress in hormone research, 1973, Volume: 29

    Topics: Animals; Chlorpromazine; Colchicine; Cytochalasin B; Glucuronidase; Lithium; Mice; Microscopy, Electron; Microtubules; Mitosis; Organoids; Protein Binding; Rats; Receptors, Drug; Structure-Activity Relationship; Thyroid Gland; Thyrotropin; Time Factors; Vinblastine

1973

Other Studies

56 other study(ies) available for chlorpromazine and colchicine

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Influence of MAO-inhibitors, neuroleptics, morphine, mescaline, divascan, aconitine, and pyrogenes on prostaglandin-biosynthesis.
    Pharmacological research communications, 1977, Volume: 9, Issue:6

    Topics: Aconitine; Aconitum; Adrenochrome; Animals; Antipsychotic Agents; Aspirin; Chlorpromazine; Colchicine; Epinephrine; Female; Haloperidol; Harmaline; In Vitro Techniques; Indolequinones; Indomethacin; Kidney Medulla; Male; Mescaline; Monoamine Oxidase Inhibitors; Morphine; Phenelzine; Phenylhydrazines; Prostaglandins; Pyrogens; Rabbits; Reserpine; Semicarbazones

1977
Differential chemical protection of mammalian cells from the exotoxins of Corynebacterium diphtheriae and Pseudomonas aeruginosa.
    Infection and immunity, 1977, Volume: 16, Issue:1

    Topics: 4-Aminobenzoic Acid; Antitoxins; Bromides; Calcimycin; Cell Line; Chloromercuribenzoates; Chlorpromazine; Colchicine; Corynebacterium diphtheriae; Cytochalasin B; Demecolcine; Deoxyglucose; Dinitrophenols; Fatty Alcohols; Lidocaine; Ouabain; Procaine; Pseudomonas aeruginosa; Ruthenium Red; Sodium Fluoride; Toxins, Biological; Tuftsin

1977
Effects of microtubule-disruptive and membrane-stabilizing agents on low density lipoprotein metabolism by cultured human fibroblasts.
    Biochimica et biophysica acta, 1979, Apr-19, Volume: 552, Issue:3

    Topics: Biological Transport; Cell Membrane; Cells, Cultured; Chlorpromazine; Colchicine; Fibroblasts; Humans; Lidocaine; Lipoproteins, LDL; Microtubules; Skin; Sucrose; Vinblastine

1979
Reversal of morphological differentiation of mouse neuroblastoma cells by mitosis-inhibitors and anesthetics.
    Virchows Archiv. B, Cell pathology, 1975, Nov-07, Volume: 19, Issue:2

    Topics: Animals; Cell Aggregation; Cell Differentiation; Chlorpromazine; Colchicine; Griseofulvin; Lidocaine; Mice; Microtubules; Mitosis; Neuritis; Neuroblastoma; Sodium Dodecyl Sulfate; Tetracaine; Vinblastine

1975
Selective and opposing effects of cytochalasin B and other drugs on lymphocyte responses to different doses of mitogens.
    Cellular immunology, 1977, Volume: 30, Issue:1

    Topics: Animals; Cell Adhesion; Chloroquine; Chlorpromazine; Colchicine; Concanavalin A; Cytochalasin B; Dose-Response Relationship, Immunologic; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA; Mitogens; Time Factors

1977
Effects of psychotropic drugs on neurotubule assembly.
    Journal of neurochemistry, 1977, Volume: 28, Issue:6

    Topics: Binding Sites; Brain; Cells, Cultured; Chlorpromazine; Colchicine; Dextroamphetamine; Dose-Response Relationship, Drug; Microtubules; Nerve Fibers; Neuroblastoma; Psychotropic Drugs; Reserpine; Tubulin; Viscosity

1977
Effect of local anesthetics on plasma protein secretion by rat hepatocytes.
    Biochimica et biophysica acta, 1977, Nov-07, Volume: 500, Issue:1

    Topics: Anesthetics, Local; Animals; Blood Proteins; Chlorpromazine; Colchicine; Cycloheximide; Leucine; Lidocaine; Liver; Rats; Serum Albumin; Subcellular Fractions

1977
Influence of Divascan, psychoactive and other drugs on prostaglandin biosynthesis and prostaglandin action.
    Acta biologica et medica Germanica, 1976, Volume: 35, Issue:8-9

    Topics: Animals; Chlorpromazine; Chromatography, Thin Layer; Colchicine; Epinephrine; Haloperidol; Morphine; Prostaglandins; Rabbits; Semicarbazones

1976
Interaction of chlorpromazine with brain microtubule subunit protein.
    Molecular pharmacology, 1975, Volume: 11, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Chick Embryo; Chlorpromazine; Colchicine; Depression, Chemical; In Vitro Techniques; Kinetics; Mice; Mice, Inbred ICR; Microtubules; Nerve Tissue Proteins; Protein Binding; Swine; Tubulin

1975
Tumor cell permeability to peplomycin.
    The Journal of antibiotics, 1989, Volume: 42, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Ehrlich Tumor; Chlorpromazine; Chromatography, High Pressure Liquid; Colchicine; Dibucaine; Dose-Response Relationship, Drug; Leukemia L1210; Leukemia P388; Liver Neoplasms, Experimental; Peplomycin; Permeability; Time Factors; Tumor Cells, Cultured; Vinblastine

1989
Involvement of erythrocyte skeletal proteins in the modulation of membrane fluidity by phenothiazines.
    Biochemistry, 1987, Dec-15, Volume: 26, Issue:25

    Topics: Chlorpromazine; Colchicine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Kinetics; Membrane Fluidity; Membrane Proteins; Trifluoperazine; Vinblastine

1987
Cyclic AMP formation and thyroid secretion by incubated mouse thyroid lobes.
    Endocrinology, 1972, Volume: 91, Issue:6

    Topics: Animals; Calcium; Chlorpromazine; Colchicine; Cyclic AMP; Cytochalasin B; In Vitro Techniques; Iodine; Iodine Isotopes; Lithium; Male; Mice; Ouabain; Sodium; Stimulation, Chemical; Theophylline; Thyroid Gland; Thyrotropin; Time Factors

1972
Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.
    The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:3

    Topics: Animals; Bucladesine; Carrageenan; Chemotaxis; Chloroquine; Chlorpromazine; Chromium Radioisotopes; Clonidine; Colchicine; Cyclophosphamide; Female; Flufenamic Acid; Indomethacin; Inflammation; Leukocyte Transfusion; Leukocytes; Methylprednisolone; Monocytes; Neutrophils; Phenylbutazone; Rats; Transplantation, Homologous; Venoms; Vinblastine

1974
Role of thiamine metabolism in the central nervous system. II. Effects of various agents on thiamine triphosphatase activity in rat brain.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:6

    Topics: Acetylcholine; Animals; Brain; Chlorpromazine; Colchicine; Fasting; In Vitro Techniques; Insulin; Liver; Male; Methamphetamine; Microsomes; Norepinephrine; Phenytoin; Phosphoric Acids; Phosphoric Monoester Hydrolases; Rats; Reserpine; Thiamine; Thiamine Deficiency; Tyramine

1974
The influence of pregnancy on the acute toxicity of various compounds in mice.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:4

    Topics: Animals; Aspirin; Body Weight; Chlorpromazine; Colchicine; Female; Fetus; Folic Acid; Iron-Dextran Complex; Lethal Dose 50; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal; Toxicology

1972
Influence of acetylsalicylic acid, butazolidine, colchicine, hydrocortisone, chlorpromazine and imipramine on the phagocytosis of polystyrene latex particles by human leucocytes.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Aspirin; Chlorpromazine; Colchicine; Humans; Hydrocortisone; Imipramine; In Vitro Techniques; Latex; Leukocytes; Microspheres; Oxygen Consumption; Phagocytosis; Phenylbutazone; Polystyrenes

1971
Studies on agranulocytosis. 8. Inhibition of mitosis in phytohemagglutinin-stimulated lymphocytes by chlorpromazine.
    The Journal of laboratory and clinical medicine, 1967, Volume: 70, Issue:2

    Topics: Agranulocytosis; Antibodies; Cell Division; Chlorpromazine; Colchicine; Culture Techniques; Humans; Lymphocytes; Microscopy

1967
[Modulating effects of phenothiazines on mast cells deformities induced by colchicine. Importance of calcium].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1982, Volume: 176, Issue:2

    Topics: Animals; Chlorpromazine; Colchicine; Kinetics; Leukocytes; Mast Cells; Phenothiazines; Promethazine; Rats; Rats, Inbred Strains; Trifluoperazine

1982
Cytoskeletal disarrangement in rat intestinal epithelium after in vivo exposure to secretagogues.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1984, Volume: 92, Issue:2

    Topics: Animals; Bacterial Toxins; Bucladesine; Chloroquine; Chlorpromazine; Cholera Toxin; Colchicine; Cytochalasin B; Cytoskeleton; Enterotoxins; Epithelium; Escherichia coli; Escherichia coli Proteins; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Rats; Rats, Inbred Strains

1984
Membrane and metabolic requirements for tolerance induction of neonatal B cells.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 133, Issue:4

    Topics: Animals; Animals, Newborn; B-Lymphocytes; Chlorpromazine; Colchicine; Cytarabine; Cytochalasins; Hydroxyurea; Immune Tolerance; Immunologic Capping; Lymphocyte Activation; Lymphocyte Depletion; Macrophages; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tubercidin

1984
Interaction of wheat germ agglutinin with human platelets: a model for studying platelet response.
    Thrombosis research, 1984, Dec-01, Volume: 36, Issue:5

    Topics: Alprostadil; Arginine; Blood Platelets; Chlorpromazine; Colchicine; Creatine Kinase; Cytochalasin B; Edetic Acid; Humans; In Vitro Techniques; Indomethacin; Lectins; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Wheat Germ Agglutinins

1984
Are membrane properties essential for the circadian rhythm of Gonyaulax?
    The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2

    Topics: Animals; Cell Cycle; Cell Division; Cerulenin; Chlorpromazine; Circadian Rhythm; Colchicine; Dinoflagellida; Fluorescence Polarization; Lidocaine; Luminescent Measurements; Membranes; Procaine; Temperature; Time Factors

1984
Chlorpromazine dissociates effects of colchicine on metabolism of triglycerides and alkaline phosphatase activity in rat liver.
    Indian journal of biochemistry & biophysics, 1984, Volume: 21, Issue:6

    Topics: Alkaline Phosphatase; Animals; Chlorpromazine; Colchicine; Female; Liver; Rats; Triglycerides

1984
[Effect of neurotropic compounds on the transmembrane potential of synaptosomes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:9

    Topics: Animals; Cerebral Cortex; Chlorpromazine; Colchicine; Cytochalasin B; Diazepam; Enkephalin, Leucine; Enkephalin, Methionine; Haloperidol; Imipramine; Membrane Potentials; Peptides; Psychotropic Drugs; Rats; Synaptosomes; Trifluoperazine; Tuftsin

1983
Preaggregation reactions of platelets.
    Blood, 1981, Volume: 58, Issue:3

    Topics: Adenosine Diphosphate; Blood Platelets; Blood Volume; Centrifugation; Chlorpromazine; Colchicine; Cytoplasmic Granules; Edetic Acid; Epinephrine; Humans; Platelet Aggregation; Temperature; Thrombin; Time Factors

1981
Delay by drugs of adrenergic nerve degeneration after proximal or distal sympathectomy of the submaxillary gland.
    General pharmacology, 1982, Volume: 13, Issue:3

    Topics: Acid Phosphatase; Animals; Body Temperature; Bretylium Compounds; Chlorpromazine; Colchicine; Denervation; Female; Lysosomes; Nerve Degeneration; Nerve Endings; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Submandibular Gland; Sympathectomy

1982
E rosette dissociation: evidence for a role of the cytoskeleton.
    Clinical and experimental immunology, 1982, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Azides; Cell Membrane; Chlorpromazine; Colchicine; Cytochalasin B; Erythrocytes; Humans; Immunologic Capping; Lymphocytes; Rosette Formation; Sodium Azide

1982
Identification of an intracellular pathway of thyroxine synthesis by dispersed thyroid cells.
    Biochimica et biophysica acta, 1981, Aug-05, Volume: 676, Issue:1

    Topics: Animals; Chlorpromazine; Colchicine; Fluorides; Iodine; Iodoproteins; Propranolol; Swine; Thyroid Gland; Thyroxine; Vinblastine

1981
Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells.
    British journal of cancer, 1998, Volume: 78, Issue:3

    Topics: Biological Transport; Calcium; Cell Membrane; Chlorpromazine; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Kinetics; Leukemia; Phenoxybenzamine; Tumor Cells, Cultured; Vinblastine

1998
Albumin facilitates zinc acquisition by endothelial cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 224, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Chlorpromazine; Colchicine; Culture Media; Cytochalasin B; Endocytosis; Endothelium, Vascular; Kinetics; Lipoproteins, LDL; Potassium; Pulmonary Artery; Serum Albumin, Bovine; Zinc

2000
Selective modulation of P-glycoprotein-mediated drug resistance.
    British journal of cancer, 2001, Dec-14, Volume: 85, Issue:12

    Topics: Allosteric Regulation; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Calcium Channel Blockers; Cell Division; Cell Membrane; Chlorpromazine; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Membrane Lipids; Neoplasm Proteins; Phospholipids; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Temperature; Tumor Cells, Cultured; Verapamil; Vinblastine

2001
[Cytological and toxicological studies on the influence of megaphen on colchicine effects].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1955, Volume: 226, Issue:6

    Topics: Animals; Chlorpromazine; Colchicine; Leadership; Neoplasms, Experimental

1955
A note on the effects on the growth of tumors of a combined treatment with chlorpromazine and a "mitotic poison".
    Hospital (Rio de Janeiro, Brazil), 1963, Volume: 63

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Chlorpromazine; Colchicine; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Poisons; Sarcoptes scabiei

1963
[Research on the mass effects in the fish Gambusia holbrooki. III. Action of cocaine, amobarbital and colchicine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Jul-10, Volume: 157

    Topics: Amobarbital; Amphetamine; Amphetamines; Animals; Chlorpromazine; Cocaine; Colchicine; Cyprinodontiformes; Fishes; Research; Sympathomimetics

1963
STUDIES ON ANTIBODY PRODUCTION. XII. INHIBITION OF PRIMING BY DRUGS.
    The Journal of experimental medicine, 1964, Dec-01, Volume: 120

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Antiprotozoal Agents; Azaguanine; Chloramphenicol; Chlorpromazine; Colchicine; Dactinomycin; Edetic Acid; Hydrocortisone; Immunization; Mercaptopurine; Methotrexate; Mice; Pharmacology; Quinolines; Research; Thiotepa; Vaccination

1964
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis; Colchicine; Cyclosporine; Diethylnitrosamine; Drug-Related Side Effects and Adverse Reactions; Ethinyl Estradiol; Female; Gene Expression Profiling; Hepatocytes; Humans; Liver; Male; Methyltestosterone; Middle Aged; Necrosis; Phenotype; Toxicogenetics; Young Adult

2016
Effect of inhibitors of endocytosis and NF-kB signal pathway on folate-conjugated nanoparticle endocytosis by rat Kupffer cells.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Amiloride; Animals; Chlorpromazine; Clathrin; Colchicine; Cytokines; Endocytosis; Epirubicin; Folic Acid; Glucans; I-kappa B Proteins; Kupffer Cells; Macrophages; Nanoparticles; NF-kappa B; Nystatin; Pyrrolidines; Rats, Sprague-Dawley; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha

2017
The comet assay applied to HepG2 liver spheroids.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2019, Volume: 845

    Topics: Cell Culture Techniques; Cell Survival; Chlorpromazine; Colchicine; Comet Assay; DNA Damage; DNA, Neoplasm; Guanine; Hep G2 Cells; Humans; Hydrogen Peroxide; Laboratory Proficiency Testing; Methyl Methanesulfonate; Sensitivity and Specificity; Spheroids, Cellular

2019