chlorpromazine and clomipramine

chlorpromazine has been researched along with clomipramine in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199034 (44.74)18.7374
1990's13 (17.11)18.2507
2000's10 (13.16)29.6817
2010's17 (22.37)24.3611
2020's2 (2.63)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Horvath, D1
Pajeva, I; Wiese, M1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Abraham, MH; Acree, WE; Ibrahim, A1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Amado, Mdel R; Carrillo, AK; Galarreta, BC; Maruenda, H; Sanchez, L; Sifuentes, R1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Dhawan, NS; Izadmehr, S; Kastrinsky, DB; Narla, G; Ohlmeyer, M; Sangodkar, J; Zaware, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dexheimer, TS; Jones, CL; Njomen, E; Sjögren, B; Tepe, JJ1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chern, YF; Chow, CF; Li, YP; Lin, MT1
Lüllmann-Rauch, R; Scheid, D1
Fletcher, HP; Schnell, RC; Wannarka, GL1
Lee, RL; Spencer, PS1
Meltzer, HY; Stahl, SM1
Elferink, JG1
Finance, F; Rohmer, F; Ruh-Bernhardt, D; Singer, L1
Krupp, P; Wesp, M1
Oksenkrug, GF1
Fukuda, Y; Ishikawa, T; Maekawa, T; Sakabe, T; Sari, A1
Finance, MF; Ruh, MD; Singer, L1
Hegenscheid, B; Presber, HW1
Futuro-Neto, HA; Pires, JG; Silva, SR1
Bru, P; Cointe, R; Dussarat, GV; Levy, S; Mafart, B1
Kehoe, R; Young, A1
Ferrari, C; Marmiroli, N; Puglisi, PP; Sabatini, MA; Tedeschi, F; Truzzi, G1
Araki, Y; Eto, K; Fukuda, T; Inoue, B; Ogata, M1
Della Corte, L; Giovannini, MG; Ninci, R; Sgaragli, G1
Lamb, RJ; McMillan, DE1
Anselmi, E; Sevilla, E; Villar, A1
Amory, C; Mainard, F1
Daly, JW; Huang, M1
Lüllmann-Rauch, R1
Kocher, R; Rohrer, G1
Bianchetti, G; Dugas, M; Morselli, PL1
Scuvée-Moreau, JJ; Svensson, TH1
Mehendale, HM; Morita, T1
Luczynska, C; Wilson, K1
Herzog, DB1
Battistini, N; Borghesi, R; Della Corte, L; Nardini, M; Ninci, R; Sgaragli, GP1
Della Corte, L; Franco, C; Giovannini, MG; Nardini, M; Ninci, R; Sgaragli, GP1
Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S1
Corte, LD; Pietro Sgaragli, G1
Imamura, A; Maekawa, T; Oshibuchi, T; Takeshita, H1
Graf, U; van Schaik, N1
Della Corte, L; Giovannini, MG; Palmi, M; Sgaragli, GP; Valoti, M1
Airaudo, CB; Bianchi, C; Gayte-Sorbier, A; Verdier, M1
Bianchi, L; Della Corte, L; Frosini, M; Giovannini, MG; Palmi, M; Sgaragli, GP; Valoti, M1
Gillman, PK1
Graham, PM1
De Matteis, F; Frosini, M; Palmi, M; Sgaragli, G; Valoti, M1
Beyssen, ML; Buxeraud, J; Cledat, D; Lagorce, JF1
Larsson, BS; Mårs, U1
Bourdel, MC; Castelnau, C; Galinowski, A; Loo, H; Olie, JP; Poirier, MF; Spreux-Varoquaux, O1
Adachi, N; Ameno, K; Hishida, S; Kasuda, S; Kinoshita, H; Komeda, M; Matsui, K; Minami, T; Motomura, H; Nishiguchi, M; Ohta, T; Ohtsu, N; Ouchi, H; Takahashi, M; Yamamura, T; Yoshida, S1
Nakagawa, T; Nishi, K; Takase, I; Yamamoto, Y1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S1

Reviews

4 review(s) available for chlorpromazine and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021
The clinical significance of the effects of cigarette smoking on drug disposition.
    Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:7

    Topics: Acetaminophen; Antipyrine; Benzodiazepines; Chlorpromazine; Clomipramine; Codeine; Humans; Pharmaceutical Preparations; Phenacetin; Propranolol; Smoking; Theophylline; Warfarin

1983
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs

1984

Trials

3 trial(s) available for chlorpromazine and clomipramine

ArticleYear
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Dec-31, Volume: 63, Issue:52

    Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents

1974
Pharmacotherapy of anorexia nervosa and bulimia.
    Pediatric annals, 1984, Volume: 13, Issue:12

    Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs

1984
Evolution of plasma homovanillic acid (HVA) levels during treatment in schizo-affective disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Agents; Chlorpromazine; Chromatography, High Pressure Liquid; Clomipramine; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders

2000

Other Studies

70 other study(ies) available for chlorpromazine and clomipramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
A virtual screening approach applied to the search for trypanothione reductase inhibitors.
    Journal of medicinal chemistry, 1997, Jul-18, Volume: 40, Issue:15

    Topics: Algorithms; Databases, Factual; Enzyme Inhibitors; Models, Chemical; Molecular Conformation; NADH, NADPH Oxidoreductases; Thermodynamics

1997
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.
    Bioorganic & medicinal chemistry, 2008, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Biological Products; Enzyme Inhibitors; Flavins; Harmaline; Indole Alkaloids; Leishmania; NADH, NADPH Oxidoreductases; Quinolines; Trypanocidal Agents; Trypanosoma cruzi

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Reengineered tricyclic anti-cancer agents.
    Bioorganic & medicinal chemistry, 2015, Oct-01, Volume: 23, Issue:19

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compounds, 3-Ring; Humans; Mice; Neoplasms; Phenothiazines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous; Vesicular Monoamine Transport Proteins

2015
Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins.
    ACS chemical biology, 2017, 09-15, Volume: 12, Issue:9

    Topics: alpha-Synuclein; Cell Line, Tumor; Chlorpromazine; HEK293 Cells; Humans; Intrinsically Disordered Proteins; Molecular Docking Simulation; Oxidative Stress; Proteasome Endopeptidase Complex; Proteolysis; Small Molecule Libraries; tau Proteins

2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats.
    Pharmacology, 1979, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Body Temperature Regulation; Brain; Chlorpromazine; Clomipramine; Fenclonine; Fluoxetine; Hypothermia; Male; Nialamide; Propylamines; Raphe Nuclei; Rats; Serotonin; Tryptophan

1979
Intraalveolar foam cells associated with lipidosis-like alterations in lung and liver of rats treated with tricyclic psychotropic drugs.
    Virchows Archiv. B, Cell pathology, 1975, Nov-21, Volume: 19, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Endoplasmic Reticulum; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Liver; Macrophages; Male; Pulmonary Alveoli; Rats; Thioridazine

1975
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine; Hyperglycemia; Imipramine; Insulin; Islets of Langerhans; Male; Mice; Promazine

1979
The effect of clomipramine and other amine-uptake inhibitors on morphine analgesia in laboratory animals.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 4

    Topics: Analgesia; Animals; Chlorpromazine; Clomipramine; Dibenzazepines; Dibenzocycloheptenes; Drug Synergism; Drug Tolerance; Male; Maprotiline; Mice; Morphine; Pentazocine; Phenyl Ethers; Proadifen; Propylamines; Quipazine; Rats

1977
Serotonin accumulation by skeletal muscle.
    Experimental neurology, 1977, Volume: 54, Issue:1

    Topics: Animals; Biological Transport; Chlorpheniramine; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Imipramine; Iprindole; Male; Muscles; Muscular Dystrophies; Procaine; Rats; Serotonin; Temperature; Urea

1977
Fluorescence studies of membrane interactions of chlorpromazine and chlorimipramine.
    Biochemical pharmacology, 1977, Mar-15, Volume: 26, Issue:6

    Topics: Anilino Naphthalenesulfonates; Animals; Binding Sites; Chlorpromazine; Clomipramine; Dibenzazepines; Erythrocyte Membrane; Erythrocytes; Kinetics; Liposomes; Spectrometry, Fluorescence; Swine; Tryptophan

1977
[Influence of psychotropic therapy on thrombogenesis and platelet functions. A propos of 4 cases of thromboembolic accidents occurring in patients treated by neuroleptics and antidepressants].
    L'Encephale, 1976, Volume: 2, Issue:3

    Topics: Aged; Antidepressive Agents; Chlorpromazine; Clomipramine; Female; Humans; Lorazepam; Middle Aged; Platelet Aggregation; Pulmonary Embolism; Thromboembolism; Thrombophlebitis; Tranquilizing Agents

1976
Inhibition of prostaglandin synthetase by psychotropic drugs.
    Experientia, 1975, Mar-15, Volume: 31, Issue:3

    Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles

1975
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 80, Issue:8

    Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines

1975
Effects of psychotropic drugs on canine cerebral metabolism and circulation related to EEG--diazepam, clomipramine, and chlorpromazine.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:9

    Topics: Animals; Brain; Cerebrovascular Circulation; Chlorpromazine; Clomipramine; Depression, Chemical; Diazepam; Dogs; Electroencephalography; Hemodynamics; Oxygen Consumption; Psychotropic Drugs

1975
[Pulmonary embolisms occurring in 1 month in 3 aged women with manic-depressive psychoses. Discussion. Etiopathogenic role or psychiatric treatment].
    Annales medico-psychologiques, 1975, Volume: 1, Issue:2

    Topics: Aged; Antidepressive Agents; Bipolar Disorder; Chlorpromazine; Clomipramine; Depressive Disorder, Major; Dibenzazepines; Female; Humans; Leg; Lorazepam; Middle Aged; Pulmonary Embolism; Thrombophlebitis

1975
[Antiprotozoal effects of benzodiazepine derivatives].
    Angewandte Parasitologie, 1990, Volume: 31, Issue:4

    Topics: Animals; Benzodiazepines; Chlorpromazine; Clomipramine; Crithidia; Desipramine; Eukaryota; Imipramine; Leishmania mexicana; Metronidazole; Trichomonas vaginalis; Trypanosoma cruzi

1990
Inhibition of chlorpromazine-induced catalepsy by the 5-HT-1A ligands pindolol and buspirone in mice.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:9

    Topics: Animals; Buspirone; Catalepsy; Chlorpromazine; Clomipramine; Female; Haloperidol; Male; Mice; Pindolol; Receptors, Serotonin

1990
[Arrhythmogenic effects of antidepressive agents demonstrated by programmed ventricular pacing].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Cardiac Pacing, Artificial; Chlorpromazine; Clomipramine; Electrocardiography; Female; Humans; Middle Aged; Ventricular Fibrillation

1989
Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Agranulocytosis; Antipsychotic Agents; Chlorpromazine; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Droperidol; Drug Therapy, Combination; Female; Flupenthixol; Fluphenazine; Humans; Long-Term Care; Male; Middle Aged; Paranoid Disorders; Psychotic Disorders

1989
Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II. Effects of central nervous system drugs upon pathogenic and non-pathogenic Candida species.
    Biology of the cell, 1985, Volume: 53, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Candida; Cell Division; Chlorpheniramine; Chlorpromazine; Clomipramine; Cytochromes; Electrophoresis, Polyacrylamide Gel; Imipramine; Mitochondria; Oxygen Consumption; Promazine

1985
Effect of tricyclic drugs on mitochondrial membrane.
    Acta medica Okayama, 1985, Volume: 39, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Imipramine; In Vitro Techniques; Intracellular Membranes; Male; Mitochondria, Liver; Oxygen Consumption; Permeability; Potassium; Promethazine; Rats

1985
Isothermal gas chromatographic determination of nanogram amounts of chlorimipramine, chlorpromazine and their N-desmethyl metabolites in plasma using nitrogen-selective detection.
    Journal of chromatography, 1986, Sep-05, Volume: 381, Issue:2

    Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Desipramine; Humans; Indicators and Reagents

1986
Some effects of chlorimipramine and imipramine on the schedule-controlled behavior of the pigeon.
    Psychopharmacology, 1985, Volume: 87, Issue:1

    Topics: Animals; Chlorpromazine; Clomipramine; Columbidae; Conditioning, Psychological; Imipramine; Male; Punishment; Structure-Activity Relationship

1985
Effects of chlorpromazine and the antidepressant drugs amitriptyline, clomipramine and mianserin on the Ca-depleted rat uterus.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium; Chlorpromazine; Clomipramine; Edetic Acid; Female; Mianserin; Oxytocin; Rats; Rats, Inbred Strains; Uterine Contraction

1985
[Mechanism of uncoupling action of tricyclic derivatives chemically related to phenothiazine].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1974, Dec-23, Volume: 279, Issue:26

    Topics: Adenosine Triphosphatases; Animals; Chlorpromazine; Clomipramine; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Phenothiazines; Promazine; Rats; Thiazines; Uncoupling Agents

1974
Interrelationships among the levels of ATP, adenosine and cyclic AMP in incubated slices of guinea-pig cerebral cortex: effects of depolarizing agents, psychotropic drugs and metabolic inhibitors.
    Journal of neurochemistry, 1974, Volume: 23, Issue:2

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimetabolites; Batrachotoxins; Carbon Radioisotopes; Cerebral Cortex; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Clomipramine; Cyclic AMP; Dibenzazepines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Norepinephrine; Ouabain; Potassium; Prenylamine; Serotonin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Veratrine

1974
Lipidosis-like ultrastructural alterations in rat lymph nodes after treatment with tricyclic antidepressants or neuroleptics.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 286, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Rats; Thioridazine

1974
Therapeutic drug monitoring of psychotropic drugs in children.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Imipramine; Kinetics; Mental Disorders; Nortriptyline

1983
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
    Journal of neural transmission, 1982, Volume: 54, Issue:1-2

    Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine

1982
Drug-specificity in the perturbation of pulmonary disposition of serotonin in rabbit in vivo.
    Pharmacology, 1983, Volume: 27, Issue:5

    Topics: Animals; Chlorpromazine; Clomipramine; Imipramine; Lung; Male; Propranolol; Rabbits; Radioisotope Dilution Technique; Serotonin

1983
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Sep-30, Volume: 60, Issue:9

    Topics: Chlorpromazine; Clomipramine; Depression; Dissociative Disorders; Humans; Imipramine

1984
[A microanalytical gas liquid chromatography method with a nitrogen-phosphorus detector in the assay of various psychotropic drugs of tricyclic structure and of their N-demethylated metabolites].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Sep-30, Volume: 60, Issue:9

    Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Humans; Imipramine; Microchemistry; Nitrogen; Phosphorus

1984
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:2

    Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; Desipramine; Diazepam; Humans; Injections; Male; Microinjections; Olfactory Bulb; Rats; Rats, Inbred Strains; Time Factors

1984
N-Dealkylation of chlorpromazine and chlorimipramine in normal volunteers.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Adult; Chlorpromazine; Clomipramine; Dealkylation; Female; Humans; Male

1984
Effects of psychotropic drugs on the cerebral energy state and glycolytic metabolism in the rat: diazepam, clomipramine and chlorpromazine.
    Biochemical pharmacology, 1980, Jan-01, Volume: 29, Issue:1

    Topics: Animals; Blood Pressure; Brain; Chlorpromazine; Clomipramine; Diazepam; Energy Metabolism; Glycolysis; Hydrogen-Ion Concentration; Male; Oxygen Consumption; Psychotropic Drugs; Rats

1980
Structure-activity relationships of tricyclic antidepressants and related compounds in the wing somatic mutation and recombination test of Drosophila melanogaster.
    Mutation research, 1993, Volume: 286, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; CHO Cells; Clomipramine; Cricetinae; Drosophila melanogaster; Female; Lofepramine; Male; Maprotiline; Mianserin; Mutagenicity Tests; Mutagens; Recombination, Genetic; Structure-Activity Relationship

1993
Pharmacokinetics of chlorimipramine, chlorpromazine and their N-dealkylated metabolites in plasma of healthy volunteers after a single oral dose of the parent compounds.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:9

    Topics: Administration, Oral; Adult; Chlorpromazine; Chromatography, Gas; Clomipramine; Female; Humans; Kinetics; Male

1993
Interactions between six psychotherapeutic drugs and plastic containers. Influence of plastic material and infusion solutions.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:6

    Topics: Chlorpromazine; Clomipramine; Clorazepate Dipotassium; Diazepam; Humans; Infusions, Parenteral; Maprotiline; Polyethylenes; Polyvinyl Chloride; Psychotropic Drugs; Viloxazine

1993
Rat tissue concentrations of chlorimipramine, chlorpromazine and their N-demethylated metabolites after a single oral dose of the parent compounds.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: Adipose Tissue; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Brain; Chlorpromazine; Chromatography, Gas; Clomipramine; Erythrocytes; Kidney; Liver; Lung; Male; Methylation; Myocardium; Rats; Rats, Sprague-Dawley; Spleen; Tissue Distribution

1995
Successful treatment of serotonin syndrome with chlorpromazine.
    The Medical journal of Australia, 1996, Sep-16, Volume: 165, Issue:6

    Topics: Central Nervous System Diseases; Chlorpromazine; Clomipramine; Depression; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Syndrome; Tranylcypromine

1996
Successful treatment of the toxic serotonin syndrome with chlorpromazine.
    The Medical journal of Australia, 1997, Feb-03, Volume: 166, Issue:3

    Topics: Akathisia, Drug-Induced; Chlorpromazine; Clomipramine; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Tranylcypromine

1997
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:9

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; beta-Naphthoflavone; Chlorpromazine; Clomipramine; Cytochrome P-450 Enzyme System; Dealkylation; Drug Interactions; Enzyme Inhibitors; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Substrate Specificity

1998
Influence of dietary iodine on drug-induced hypothyrodism in the rat.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:6

    Topics: Animals; Antithyroid Agents; Chlorpromazine; Clomipramine; Female; Hypothyroidism; Iodine; Lactoperoxidase; Organ Size; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Thyroid Gland; Thyrotropin

1999
Pheomelanin as a binding site for drugs and chemicals.
    Pigment cell research, 1999, Volume: 12, Issue:4

    Topics: Albinism; Animals; Autoradiography; Binding Sites; Carbon Radioisotopes; Chloroquine; Chlorpromazine; Clomipramine; Cysteine; Hair Color; Melanins; Mice; Mice, Inbred C57BL; Skin; Thiourea

1999
Forensic toxicological implication of an autopsy case of mixed drug overdose involving clomipramine, chlorpromazine and flunitrazepam.
    Soudni lekarstvi, 2008, Volume: 53, Issue:3

    Topics: Adult; Chlorpromazine; Clomipramine; Female; Flunitrazepam; Humans; Psychotropic Drugs; Suicide

2008
A fatal case of potential chronic overdoses of prescribed and proprietary remedies.
    Human & experimental toxicology, 2010, Volume: 29, Issue:8

    Topics: Adult; Analgesics; Caffeine; Chlorpromazine; Clomipramine; Drug Overdose; Fatal Outcome; Heart Arrest; Humans; Liver; Lung; Male; Pulmonary Edema; Substance Abuse Detection

2010
Interaction of injectable neurotropic drugs with the red cell membrane.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7

    Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid

2014
An autopsy case of drowning under the influence of multiple psychotropic drugs.
    Archiwum medycyny sadowej i kryminologii, 2019, Volume: 69, Issue:4

    Topics: Adult; Autopsy; Chlorpromazine; Clomipramine; Drowning; Drug Overdose; Female; Flunitrazepam; Forensic Medicine; Humans; Psychotropic Drugs

2019