chlorpromazine and clofibrate

chlorpromazine has been researched along with clofibrate in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's1 (4.55)18.2507
2000's3 (13.64)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Aznar Reig, A; Bolaños Díaz, A; De la Vega Vázquez, JM; Fajardo Gálvez, J; Holgado Silva, C1
Phillips, WA; Ratchford, JM; Schultz, JR1
Bowley, M; Brindley, DN1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M1
Acosta, D; Wenzel, DG1
McIntosh, DA; Topham, JC1
Epstein, LH1
Asada, S; Mizumori, N; Sano, K; Shin, M; Umezawa, C1

Reviews

4 review(s) available for chlorpromazine and clofibrate

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The effect of drugs on bile flow and composition. An overview.
    Drugs, 1986, Volume: 31, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid

1986
The direct effects of compliance on health outcome.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 1984, Volume: 3, Issue:4

    Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug Therapy; Humans; Neoplasms; Obesity; Patient Compliance; Placebos; Random Allocation; Schizophrenia

1984

Trials

1 trial(s) available for chlorpromazine and clofibrate

ArticleYear
The direct effects of compliance on health outcome.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 1984, Volume: 3, Issue:4

    Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug Therapy; Humans; Neoplasms; Obesity; Patient Compliance; Placebos; Random Allocation; Schizophrenia

1984

Other Studies

18 other study(ies) available for chlorpromazine and clofibrate

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Diabetes insipidus. Clinico-pharmalogical correlations and their therapeutic results with various substances].
    Revista clinica espanola, 1978, Feb-28, Volume: 148, Issue:4

    Topics: Carbamazepine; Chlorpromazine; Clofibrate; Diabetes Insipidus; Diuresis; Drug Evaluation; Drug Therapy, Combination; Humans; Osmolar Concentration; Vasopressins

1978
Effects of colestipol hydrochloride on drug absorption in the rat II.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:9

    Topics: Animals; Cellulose; Chlorpromazine; Cholestyramine Resin; Clofibrate; Colestipol; Digitoxin; Digoxin; Hydrochlorothiazide; Intestinal Absorption; Male; Nicotinic Acids; Pharmaceutical Preparations; Phenobarbital; Polyamines; Rats; Tetracycline; Warfarin

1976
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine, mepyramine and some of their derivatives.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Amphetamine; Animals; Chlorpromazine; Clofenapate; Clofibrate; Dibucaine; Fenfluramine; Glycerides; Glycerol-3-Phosphate O-Acyltransferase; Halofenate; Imipramine; In Vitro Techniques; Kinetics; Liver; Pharmacology; Phospholipids; Pyrilamine; Rats

1975
Permeability of lysosomes and mitochondria in cultured rat heart muscle and endotheloid cells as affected by vitamin A, chlorpromazine, amphotericin B, and clofibrate.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Amphotericin B; Animals; Cells, Cultured; Chlorpromazine; Clofibrate; Endothelium; Feedback; Heart; Hydrocortisone; In Vitro Techniques; Lysosomes; Mitochondria, Muscle; Myocardium; Osmotic Fragility; Permeability; Rats; Staining and Labeling; Succinate Dehydrogenase; Time Factors; Vitamin A

1973
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity

1972
Effect of thioridazine or chlorpromazine on increased hepatic NAD+ level in rats fed clofibrate, a hypolipidaemic drug.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:4

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clofibrate; Hypolipidemic Agents; Liver; Male; NAD; Rats; Rats, Sprague-Dawley; Thioridazine

1998