chlorpromazine and citalopram

chlorpromazine has been researched along with citalopram in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.56)	18.7374
1990's	2 (5.56)	18.2507
2000's	15 (41.67)	29.6817
2010's	17 (47.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Keserü, GM	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Faller, B; Trunzer, M; Zimmerlin, A	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sen, S; Sinha, N	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Peters, JU	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Melzacka, M; Nocon, H	1
Sieber-Blum, M	1
Bouthillier, A; de Montigny, C	1
Earley, B; Faherty, CJ; Leonard, BE	1
Gottardo, R; Pascali, JP; Polettini, A; Tagliaro, F	1
Graudins, A; Green, D; Morris, E	1
Bennett, DJ; Chan, KM; D'Amico, JM; Finlay, MG; Gorassini, MA; Li, Y; Murray, KC	1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S	1
Bacci, M; Gioia, S; Lancia, M; Suadoni, F	1
Barygin, OI; Belinskaya, DA; Nagaeva, EI; Shestakova, NN; Tikhonov, DB; Vanchakova, NP	1

Reviews

2 review(s) available for chlorpromazine and citalopram

Article	Year
Polypharmacology - foe or friend? Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22 Topics: Animals; Communicable Diseases; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Polypharmacology; Safety	2013
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

34 other study(ies) available for chlorpromazine and citalopram

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats	2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2 Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry	2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effect of some cationic amphiphilic drugs on phospholipid methylation in the central nervous system of rats. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:2 Topics: Animals; Cerebral Cortex; Chlorpromazine; Citalopram; Desipramine; Imipramine; Injections, Intraperitoneal; Male; Methylation; Methyltransferases; Phospholipids; Rats; Rats, Inbred Strains; Synaptic Membranes	1991
Inhibition of the adrenergic phenotype in cultured neural crest cells by norepinephrine uptake inhibitors. Developmental biology, 1989, Volume: 136, Issue:2 Topics: Adrenergic Fibers; Animals; Biological Transport; Chlorpromazine; Citalopram; Coturnix; Desipramine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Mazindol; Neural Crest; Neurotransmitter Uptake Inhibitors; Norepinephrine; Tyrosine 3-Monooxygenase	1989
Long-term antidepressant treatment reduces neuronal responsiveness to flurazepam: an electrophysiological study in the rat. Neuroscience letters, 1987, Jan-27, Volume: 73, Issue:3 Topics: Acetylcholine; Action Potentials; Animals; Antidepressive Agents; Chlorpromazine; Cholecystokinin; Citalopram; Desipramine; Flurazepam; Hippocampus; Iontophoresis; Male; Propylamines; Rats; Rats, Inbred Strains; Time Factors; Trimipramine	1987
Behavioural effects of selective serotonin reuptake inhibitors following direct micro injection into the left red nucleus of the rat. Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:1 Topics: 1-Naphthylamine; Animals; Behavior, Animal; Chlorpromazine; Citalopram; Fluoxetine; Fluvoxamine; Guanidines; Haloperidol; Male; Microinjections; Motor Activity; Paroxetine; Piperidines; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Selective Serotonin Reuptake Inhibitors; Sertraline	1997
Implementation and performance evaluation of a database of chemical formulas for the screening of pharmaco/toxicologically relevant compounds in biological samples using electrospray ionization-time-of-flight mass spectrometry. Analytical chemistry, 2008, Apr-15, Volume: 80, Issue:8 Topics: Chlorpromazine; Citalopram; Cocaine; Female; Hair; Hazardous Substances; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization; Suicide	2008
Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:1 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Chlorpromazine; Citalopram; Combined Modality Therapy; Dopamine Agonists; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Hypothermia, Induced; Infusions, Intravenous; Midazolam; Neuroleptic Malignant Syndrome; Olanzapine; Respiration, Artificial; Treatment Outcome	2009
Constitutively active 5-HT2/α1 receptors facilitate muscle spasms after human spinal cord injury. Journal of neurophysiology, 2013, Volume: 109, Issue:6 Topics: Action Potentials; Adult; Aged; Biogenic Monoamines; Calcium; Case-Control Studies; Chlorpromazine; Citalopram; Dopamine Antagonists; Female; Humans; Male; Middle Aged; Motor Neurons; Muscle Spasticity; Muscle, Skeletal; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Recruitment, Neurophysiological; Reflex; Selective Serotonin Reuptake Inhibitors; Spinal Cord Injuries	2013
Interaction of injectable neurotropic drugs with the red cell membrane. Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7 Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid	2014
A Fatal Case of Acute Butane-Propane Poisoning in a Prisoner Under Psychiatric Treatment: Do These 2 Factors Have an Arrhythmogenic Interaction, Thus Increasing the Cardiovascular Risk Profile? The American journal of forensic medicine and pathology, 2015, Volume: 36, Issue:4 Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Butanes; Chlorpromazine; Citalopram; Drug Interactions; Electrocardiography; Forensic Toxicology; Humans; Inhalant Abuse; Male; Mental Disorders; Prisoners; Propane	2015
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics. Brain research, 2017, 04-01, Volume: 1660 Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Atomoxetine Hydrochloride; Brain; Chlorpromazine; Citalopram; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2017