chlorpromazine and chloroquine

chlorpromazine has been researched along with chloroquine in 107 studies

Research

Studies (107)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (50.47)	18.7374
1990's	12 (11.21)	18.2507
2000's	14 (13.08)	29.6817
2010's	22 (20.56)	24.3611
2020's	5 (4.67)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R	1
Farasati, NA; Huang, Y; Randhawa, P	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Fitos, I; Mády, G; Visy, J; Zsila, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Amsler, CD; Baker, BJ; Hahn, KN; Kyle, DE; Lebar, MD; Maignan, P; McClintock, JB; Mutka, T; van Olphen, A	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Chan, ASC; Feng, X; Hu, J; Huang, L; Li, X; Wang, Z; Yang, X	1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL	1
Kitagawa, T; Matsumoto, A; Terashima, I; Uesono, Y	1
Drenckhahn, D; Lüllmann-Rauch, R	1
Larsson, B; Tjälve, H	1
Garfinkel, E; Hirschman, SZ	1
Allison, RG; Hahn, FE	1
Eidinger, D; Gery, I	1
Crews, SJ	1
Greenseid, DZ; Zinn, KM	1
Jaanus, SD	1
Basco, LK; Le Bras, J	1
Cohen, GM; Lewis, CP; Smith, LL	1
Kiryon, C; Miki, A; Nakayama, T; Ohsawa, K; Tanabe, K	1
Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG	1
Butany, J; Downar, E; Shaikh, NA	1
Scheuer, W	1
Brockelman, CR; Bunnag, D; Satayavivad, J; Tan-ariya, P; Wongsawatkul, O	1
Debing, I; Ijzerman, AP; Vauquelin, G	1
Dixon, PA; Makanjuola, RO; Oforah, E	1
Coudert, B; Dwyer, TM; Joshi, UM; Kodavanti, PR; Mehendale, HM	1
Akintonwa, DA	1
Bánhegyi, D; Fülöp, E; Várnai, F	1
Hostetler, KY; Kubo, M	1
Hockwin, O; Koch, HR	1
Lindquist, NG	1
Barg, TsM	1
Chinea, G; Oronsky, AL; Perper, RJ; Sanda, M	1
Fukao, T; Takagi, K	1
Mukhtar, H; Murti, CR	1
Sinoara, H	1
Lindquist, NG; Ullberg, S	1
Brdicska, M; Simonyi, I	1
Hochschild, R	1
Bernstein, HN	1
Lindquist, NG; Sjöstrand, SE; Ullberg, S	2
Korb, F; Prasad, KN; Van Woert, MH	1
Davidorf, FH	1
de Freudenreich, J; Duckert, A; Fabre, J; Pitton, JS; Rudhardt, M	1
Burghardt, C; Sheppard, H; Tsien, WH	1
Chin, L; Duplisse, BR; Picchioni, AL	1
Jagendorf, AT; Nishizaki, Y	1
Ellis, PP	1
Potts, AM	3
de Freudenreich, J; Duckert, A; Fabre, J; Pitton, JS; Rudhardt, M; Virieux, C	1
Hansson, HA; Lange, S; Lönnroth, I; Rozell, B; Tinberg, H	1
Hansson, HA; Lange, S; Lönnroth, I	1
Nikolov, R	1
Harris, EJ; Jackson, MJ; Jones, DA	1
Dixon, PA; Oforah, E	1
Pilger, IS	1
Andersson, A; Olsson, S; Tjälve, H	1
Slaga, TJ; Solanki, V	1
Larsson, B; Nilsson, M; Tjälve, H	2
Zarach-Krutysza, M	1
Boeyé, A; Kronenberger, P; Vrijsen, R	1
Kyle, DE; Milhous, WK; Rossan, RN	1
Buttery, M; Cormier, M; Daddona, P; Mize, NK; Morales, C	1
Bishop, NE	1
Deybach, JC; Nordmann, Y; Puy, H	1
Guo, SQ; Li, Z; Liu, JC; Lu, SM; Song, SM; Wang, ZG	1
Larsson, BS; Mårs, U	1
Bhattacharyya, D; Sen, PC	1
Deady, LW; Kalkanidis, M; Klonis, N; Tilley, L	1
BONAMOUR, G; DIDIER-LAURENT, A	1
SAPEIKA, N	1
Ikebe, T; Ikewaki, J; Imaizumi, M; Nakatsuka, K	1
Behera, SP; Dubey, SC; Mathapati, BS; Mishra, N; Nema, RK; Rajukumar, K	1
Hoffmann, GR; Laterza, AM; Sylvia, KE; Tartaglione, JP	1
Ma, DX; Qi, XR	1
Goodson, H; Helquist, P; Huegel, KL; Hulett, TW; Vaughan, KT; Wehrmann, ZT; Wiest, O	1
Heukers, R; Houtman, MJ; Man, JC; Takanari, H; Tieland, RG; van Bergen En Henegouwen, PM; van der Heyden, MA; Varkevisser, R; Vos, MA; Waasdorp, M	1
Bestebroer, TM; de Wilde, AH; Jochmans, D; Neyts, J; Posthuma, CC; Snijder, EJ; van den Hoogen, BG; van Nieuwkoop, S; Zevenhoven-Dobbe, JC	1
Emonet, S; Ferraris, O; Ferrier Rembert, A; Moroso, M; Paranhos-Baccalà, G; Pernet, O; Peyrefitte, CN	1
Bockstiegel, J; Lübow, C; Weindl, G	1
Han, YJ; Ji, XY; Li, XX; Ma, CY; Ren, ZG; Wu, DD; Yan, JL	1
Coleman, CM; Frieman, MB; Haupt, R; Li, Y; Logue, J; Matthews, K; Reyes, HM; Weiss, SR; Weston, S	1

Reviews

9 review(s) available for chlorpromazine and chloroquine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective. Medicinal research reviews, 2021, Volume: 41, Issue:1 Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization	2021
Toxicology of the retinal pigment epithelium. International ophthalmology clinics, 1975,Spring, Volume: 15, Issue:1 Topics: Animals; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Epithelium; Humans; Melanins; Retinal Diseases; Thioridazine	1975
Ocular side effects of selected systemic drugs. Optometry clinics : the official publication of the Prentice Society, 1992, Volume: 2, Issue:4 Topics: Amiodarone; Anti-Inflammatory Agents; Antirheumatic Agents; Chloroquine; Chlorpromazine; Drug Interactions; Eye Diseases; Humans; Organogold Compounds; Steroids; Sulfonamides; Vision Disorders	1992
[Eye complications during use of various medicinal substances with general effects (review of the literature)]. Oftalmologicheskii zhurnal, 1969, Volume: 24, Issue:8 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalarials; Cardiac Glycosides; Cataract; Child; Chloroquine; Chlorpromazine; Epinephrine; Ethambutol; Ethchlorvynol; Eye Diseases; Female; Humans; Miotics; Nalidixic Acid; Phosphates; Pilocarpine; Quinolines; Retinal Degeneration; Warfarin	1969
Some iatrogenic ocular diseases from systemically administered drugs. International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3 Topics: Animals; Cataract; Cats; Chemical Phenomena; Chemistry; Chloramphenicol; Chloroquine; Chlorpromazine; Clomiphene; Conjunctiva; Contraceptives, Oral; Cornea; Dark Adaptation; Dimethyl Sulfoxide; Electrooculography; Electroretinography; Eye Diseases; Humans; Iatrogenic Disease; Indomethacin; Pigmentation; Rabbits; Rats; Retina; Skin Manifestations; Vision Disorders; Visual Fields	1970
[Hepatic porphyria]. La Revue de medecine interne, 1999, Volume: 20, Issue:4 Topics: Adult; Analgesics, Opioid; Antipsychotic Agents; Charcoal; Child; Child, Preschool; Chloroquine; Chlorpromazine; Diagnosis, Differential; Female; Gonadotropin-Releasing Hormone; Hemin; Humans; Infant; Infant, Newborn; Male; Meperidine; Middle Aged; Phlebotomy; Porphyria Cutanea Tarda; Porphyria, Acute Intermittent; Porphyrias, Hepatic	1999
[Drug-induced visual disturbance]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Amiodarone; Anti-Asthmatic Agents; Antimalarials; Antitubercular Agents; Antiviral Agents; Chloroquine; Chlorpromazine; Dopamine Antagonists; Ethambutol; Eye Diseases; Glucocorticoids; Humans; Interferons; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	2007
Advances and challenges in the prevention and treatment of COVID-19. International journal of medical sciences, 2020, Volume: 17, Issue:12 Topics: Amides; Antibodies, Monoclonal; Antiviral Agents; Betacoronavirus; Chloroquine; Chlorpromazine; Coronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cyclophilins; Drug Development; Drug Repositioning; Drugs, Chinese Herbal; Endocytosis; Humans; Immune Sera; Interferon Inducers; Nucleic Acid Synthesis Inhibitors; Pandemics; Pneumonia, Viral; Pyrazines; Resveratrol; SARS-CoV-2; Viral Vaccines	2020

Trials

1 trial(s) available for chlorpromazine and chloroquine

Article	Year
Effects of antimalarial agents on plasma levels of chlorpromazine and its metabolites in schizophrenic patients. Tropical and geographical medicine, 1988, Volume: 40, Issue:1 Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chloroquine; Chlorpromazine; Drug Combinations; Drug Synergism; Female; Humans; Male; Middle Aged; Pyrimethamine; Random Allocation; Schizophrenia; Sulfadoxine	1988

Other Studies

97 other study(ies) available for chlorpromazine and chloroquine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein. Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17 Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship	2003
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication	2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein. Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7 Topics: Antimalarials; Binding Sites; Chromatography, Affinity; Circular Dichroism; Humans; Molecular Structure; Orosomucoid; Protein Binding; Serum Albumin; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs. Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19 Topics: Antimalarials; Cell Line, Tumor; Central Nervous System Agents; Humans; Indole Alkaloids; Indoles; Plasmodium falciparum; Pyrimidines; Receptors, Serotonin	2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry, 2018, 03-08, Volume: 61, Issue:5 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Proliferation; Drug Design; Hippocampus; Humans; Indoles; Ligands; Memory Disorders; Mice; Quinolines	2018
Antimalarial Quinacrine and Chloroquine Lose Their Activity by Decreasing Cationic Amphiphilic Structure with a Slight Decrease in pH. Journal of medicinal chemistry, 2021, 04-08, Volume: 64, Issue:7 Topics: Antifungal Agents; Cell Membrane; Chloroquine; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Monosaccharide Transport Proteins; Protons; Quinacrine; Saccharomyces cerevisiae; Surface-Active Agents	2021
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs. Neuroscience, 1979, Volume: 4, Issue:4 Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole; Male; Microscopy, Electron; Muscles; Muscular Diseases; Phentermine; Piperazines; Psychotropic Drugs; Quinacrine; Rats; Triparanol	1979
Studies on the mechanism of drug-binding to melanin. Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7 Topics: Animals; Binding Sites; Cattle; Chloroquine; Chlorpromazine; Hydrogen-Ion Concentration; In Vitro Techniques; Melanins; Metals; Nickel; Paraquat; Pharmaceutical Preparations; Potentiometry; Sodium	1979
Inhibition of hepatitis B DNA polymerase by intercalating agents. Nature, 1978, Feb-16, Volume: 271, Issue:5646 Topics: Chloroquine; Chlorpromazine; Drug Synergism; Ethidium; Hepatitis B; Hepatitis B virus; Humans; Indicators and Reagents; Methylene Blue; Nucleic Acid Synthesis Inhibitors; Primaquine; Quinacrine	1978
Changes in superhelical density of closed circular deoxyribonucleic acid by intercalation of anti-R-plasmid drugs and primaquine. Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:2 Topics: Acridines; Chemical Phenomena; Chemistry; Chloroquine; Chlorpromazine; DNA, Circular; Ethidium; Extrachromosomal Inheritance; Methylene Blue; Plasmids; Primaquine; Pseudomonas; Quinine	1977
Selective and opposing effects of cytochalasin B and other drugs on lymphocyte responses to different doses of mitogens. Cellular immunology, 1977, Volume: 30, Issue:1 Topics: Animals; Cell Adhesion; Chloroquine; Chlorpromazine; Colchicine; Concanavalin A; Cytochalasin B; Dose-Response Relationship, Immunologic; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred CBA; Mitogens; Time Factors	1977
Ocular adverse reactions to drugs. The Practitioner, 1977, Volume: 219, Issue:1309 Topics: Adrenal Cortex Hormones; Adult; Aged; Amblyopia; Cataract; Chloroquine; Chlorpromazine; Conjunctivitis; Corneal Diseases; Drug Hypersensitivity; Eye Diseases; Glaucoma; Humans; Middle Aged; Practolol	1977
In vitro activities of chloroquine in combination with chlorpromazine or prochlorperazine against isolates of Plasmodium falciparum. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1 Topics: Animals; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Microbial Sensitivity Tests; Plasmodium falciparum; Prochlorperazine	1992
The identification and characterization of an uptake system for taurine into rat lung slices. Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Antimycin A; Binding, Competitive; Bucladesine; Chloroquine; Chlorpromazine; Colforsin; Diamide; Kinetics; Lung; Male; Potassium Cyanide; Rats; Rats, Inbred Strains; Sodium; Taurine	1990
Plasmodium chabaudi: association of reversal of chloroquine resistance with increased accumulation of chloroquine in resistant parasites. Experimental parasitology, 1992, Volume: 74, Issue:2 Topics: Animals; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Chromatography, High Pressure Liquid; Desipramine; Drug Resistance; Erythrocytes; Female; Imipramine; Malaria; Mice; Mice, Inbred ICR; Plasmodium chabaudi; Trifluoperazine	1992
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria. Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2 Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil	1989
Amiodarone--an inhibitor of phospholipase activity: a comparative study of the inhibitory effects of amiodarone, chloroquine and chlorpromazine. Molecular and cellular biochemistry, 1987, Volume: 76, Issue:2 Topics: Amiodarone; Chloroquine; Chlorpromazine; Humans; Inclusion Bodies; Leukocytes; Microscopy, Electron; Phospholipases	1987
Phospholipase A2--regulation and inhibition. Klinische Wochenschrift, 1989, Feb-01, Volume: 67, Issue:3 Topics: Animals; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Pancreas; Phospholipases; Phospholipases A; Phospholipases A2; Swine	1989
Flunarizine and verapamil inhibit chloroquine-resistant Plasmodium falciparum growth in vitro. The Southeast Asian journal of tropical medicine and public health, 1987, Volume: 18, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Chlorpromazine; Drug Resistance; Flunarizine; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Regression Analysis; Verapamil	1987
Melanosome binding and oxidation-reduction properties of synthetic L-dopa-melanin as in vitro tests for drug toxicity. Molecular pharmacology, 1988, Volume: 33, Issue:4 Topics: Animals; Cattle; Chloroquine; Chlorpromazine; Electron Transport; Kinetics; Levodopa; Melanins; Melanocytes; NAD; Oxidation-Reduction; Pirenzepine	1988
Types of interaction of amphiphilic drugs with phospholipid vesicles. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: Amiodarone; Anilino Naphthalenesulfonates; Binding Sites; Chloramphenicol; Chloroquine; Chlorpromazine; Diphenylhexatriene; Imipramine; Lipidoses; Lung Diseases; Membrane Lipids; Phospholipids; Promethazine; Propranolol; Surface-Active Agents; Trimipramine	1988
The derivation of nitrosamines from some therapeutic amines in the human environment. Ecotoxicology and environmental safety, 1985, Volume: 9, Issue:1 Topics: Amines; Carcinogens; Chemical Phenomena; Chemistry; Chloroquine; Chlorpromazine; Humans; Methadone; Mixed Function Oxygenases; Nitrosamines; Pharmaceutical Preparations; Phenacetin; Primaquine	1985
[Cases of cutaneous leishmaniasis imported by Hungarian citizens]. Orvosi hetilap, 1985, Oct-13, Volume: 126, Issue:41 Topics: Administration, Topical; Chloroquine; Chlorpromazine; Humans; Hungary; Leishmaniasis; Travel; Tropical Climate	1985
Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. Biochemistry, 1985, Nov-05, Volume: 24, Issue:23 Topics: Animals; Chloroquine; Chlorpromazine; Kinetics; Liposomes; Liver; Lysosomes; Male; Mathematics; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A1; Propranolol; Protein Binding; Rats; Rats, Inbred Strains	1985
[Iatrogenic cataracts]. Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42 Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimethyl Sulfoxide; Drug-Related Side Effects and Adverse Reactions; Environmental Health; Histamine H1 Antagonists; Humans; Phenelzine; Piperazines; Thiotepa; Urea	1974
Accumulation of drugs on melanin. Acta radiologica: diagnosis, 1973, Volume: 325 Topics: Animals; Autoradiography; Carbon Isotopes; Catechol Oxidase; Catecholamines; Cattle; Chloroquine; Chlorpromazine; Female; Haplorhini; Histocytochemistry; Humans; In Vitro Techniques; Male; Melanins; Melanocytes; Melanoma; Mice; Microscopy, Electron; Neurons; Pregnancy; Serotonin; Streptomycin; Substantia Nigra; Sulfur Isotopes	1973
Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation. The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:3 Topics: Animals; Bucladesine; Carrageenan; Chemotaxis; Chloroquine; Chlorpromazine; Chromium Radioisotopes; Clonidine; Colchicine; Cyclophosphamide; Female; Flufenamic Acid; Indomethacin; Inflammation; Leukocyte Transfusion; Leukocytes; Methylprednisolone; Monocytes; Neutrophils; Phenylbutazone; Rats; Transplantation, Homologous; Venoms; Vinblastine	1974
Effects of some drugs on capillary permeability in the anaphylaxis of the mouse. Japanese journal of pharmacology, 1971, Volume: 21, Issue:4 Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Aprotinin; Aspirin; Body Temperature; Capillary Permeability; Chloroquine; Chlorpromazine; Cortisone; Cyclizine; Depression, Chemical; Desensitization, Immunologic; Diphenhydramine; Epinephrine; Female; Glycyrrhiza; Histamine H1 Antagonists; Indomethacin; Mice; Oxyphenbutazone; Phenylbutazone; Plants, Medicinal; Promethazine; Rectum; Reserpine; Splenectomy; Triprolidine	1971
Induction of rat liver tyrosine aminotransferase by pharmacologically unrelated drugs. Indian journal of biochemistry, 1971, Volume: 8, Issue:2 Topics: Animals; Azaguanine; Chloroquine; Chlorpromazine; Enzyme Induction; Liver; Mercaptopurine; Phenacetin; Rats; Tetracycline; Tyrosine Transaminase	1971
Amino acid transport in spores of Aspergillus oryzae. Journal of biochemistry, 1974, Volume: 76, Issue:3 Topics: Acridines; Amino Acids; Arginine; Aspergillus; Biological Transport; Carbon Radioisotopes; Cell Membrane; Chloroquine; Chlorpromazine; Cycloheximide; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leucine; Mannitol; Naphthalenesulfonates; Osmolar Concentration; Phosphates; Potassium Chloride; Pronase; Salicylates; Sodium Dodecyl Sulfate; Spores, Fungal; Time Factors	1974
The melanin affinity of chloroquine and chlorpromazine studied by whole body autoradiography. Acta pharmacologica et toxicologica, 1972, Volume: 2 Topics: Animals; Aqueous Humor; Autoradiography; Carbon Isotopes; Chloroquine; Chlorpromazine; Ear; Endocrine Glands; Eye; Female; Fetus; Hair; Haplorhini; Lymph Nodes; Male; Maternal-Fetal Exchange; Melanins; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Pregnancy; Skin; Sulfur Isotopes; Time Factors	1972
[The use of sodium lauryl sulfate volumetric solution in the study of injection solutions]. Acta pharmaceutica Hungarica, 1973, Volume: 43, Issue:6 Topics: Atropine; Chloroquine; Chlorpromazine; Codeine; Epinephrine; Injections; Lidocaine; Sodium Dodecyl Sulfate; Solutions; Tripelennamine	1973
Effects of various drugs on longevity in female C57BL-6J mice. Gerontologia, 1973, Volume: 19, Issue:5 Topics: Acetaminophen; Age Factors; Analgesics; Animals; Aspirin; Body Weight; Buffers; Cell Membrane; Chemical Phenomena; Chemistry; Chloroquine; Chlorpheniramine; Chlorpromazine; Female; Glycolates; Longevity; Mice; Mice, Inbred C57BL	1973
Accumulation of chorio-retinotoxic drugs in the foetal eye. Acta pharmacologica et toxicologica, 1970, Volume: 28, Issue:1 Topics: Animals; Autoradiography; Carbon Isotopes; Chloroquine; Chlorpromazine; Eye; Female; Fetus; Haplorhini; Injections, Intravenous; Maternal-Fetal Exchange; Mice; Pregnancy; Sulfur Isotopes	1970
Regulation of tyrosinase activity in mouse melanoma and skin by changes in melanosomal membrane permeability. The Journal of investigative dermatology, 1971, Volume: 56, Issue:5 Topics: Animals; Bile Acids and Salts; Catechol Oxidase; Cell Membrane Permeability; Chloroquine; Chlorpromazine; Chromatophores; Detergents; Digitalis Glycosides; Freezing; Homeostasis; Lysosomes; Melanins; Melanocytes; Melanoma; Mice; Microscopy, Electron; Neoplasms, Experimental; Peptide Hydrolases; Proteins; Skin; Skin Neoplasms; Steroids; Tritium; Tyrosine	1971
Ocular toxicity of systemic drugs. A review of the effects of seven commonly used agents. The Ohio State medical journal, 1972, Volume: 68, Issue:11 Topics: Chloramphenicol; Chloroquine; Chlorpromazine; Contraceptives, Oral; Eye Diseases; Glucocorticoids; Humans; Indomethacin; Thioridazine	1972
[Influence of renal insufficiency on the excretion of diverse drugs (chloroquine, sedatives, methacycline)]. Helvetica medica acta. Supplementum, 1966, May-15, Volume: 46 Topics: Barbiturates; Chloroquine; Chlorpromazine; Creatinine; Humans; Hypnotics and Sedatives; Kidney Failure, Chronic; Metabolic Clearance Rate; Methacycline; Time Factors	1966
Effect of drugs on the hemolysis of rat erythrocytes. Biochemical pharmacology, 1969, Volume: 18, Issue:9 Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Desoxycorticosterone; Digitalis Glycosides; Diuretics; Erythrocytes; Glucose; Guanethidine; Hemolysis; Hydrocortisone; Hypotonic Solutions; Indomethacin; Levorphanol; Male; Neostigmine; Rats; Tripelennamine	1969
The action of activated charcoal on poisons in the digestive tract. Toxicology and applied pharmacology, 1970, Volume: 16, Issue:3 Topics: Animals; Aspirin; Barbiturates; Charcoal; Chloroquine; Chlorpheniramine; Chlorpromazine; Digestive System; Dogs; Glutethimide; Intestinal Absorption; Liver; Male; Pentobarbital; Poisoning; Rats; Time Factors	1970
Accumulation of chorio-retinotoxic drugs in the foetal eye. Nature, 1970, Sep-19, Volume: 227, Issue:5264 Topics: Animals; Autoradiography; Chloroquine; Chlorpromazine; Eye; Female; Fetus; Mice; Pregnancy; Sulfur Isotopes	1970
Kinetics of acid efflux from chloroplasts following the acid-base transition. Biochimica et biophysica acta, 1971, Jan-12, Volume: 226, Issue:1 Topics: Acids; Adenosine Triphosphate; Ammonium Chloride; Buffers; Chloroplasts; Chloroquine; Chlorpromazine; Diffusion; Electrodes; Glass; Glutamates; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Nitriles; Phenylhydrazines; Plant Cells; Succinates; Surface-Active Agents; Temperature; Time Factors; Uncoupling Agents	1971
Ocular complications of systemic medications. Texas medicine, 1971, Volume: 67, Issue:4 Topics: Adrenal Cortex Hormones; Chloroquine; Chlorpromazine; Eye Diseases; Humans	1971
Agents which cause pigmentary retinopathy. Diseases of the nervous system, 1968, Volume: 29, Issue:3 Topics: Antibiotics, Antineoplastic; Chloroquine; Chlorpromazine; Chronic Disease; Female; Humans; Iodine; Male; Retinitis Pigmentosa; Salts; Thioridazine; Time Factors	1968
Influence of renal insufficiency on the excretion of chloroquine, phenobarbital, phenothiazines and methacycline. Helvetica medica acta, 1967, Volume: 33, Issue:4 Topics: Adult; Aged; Chloroquine; Chlorpromazine; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Methacycline; Middle Aged; Phenobarbital; Promethazine; Spectrophotometry; Ultraviolet Rays	1967
Cytoskeletal disarrangement in rat intestinal epithelium after in vivo exposure to secretagogues. Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology, 1984, Volume: 92, Issue:2 Topics: Animals; Bacterial Toxins; Bucladesine; Chloroquine; Chlorpromazine; Cholera Toxin; Colchicine; Cytochalasin B; Cytoskeleton; Enterotoxins; Epithelium; Escherichia coli; Escherichia coli Proteins; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Rats; Rats, Inbred Strains	1984
Internalization in vivo of cholera toxin in the small intestinal epithelium of the rat. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 1984, Volume: 92, Issue:1 Topics: Animals; Chloroquine; Chlorpromazine; Cholera Toxin; Epithelium; Fluorescent Antibody Technique; Immunoenzyme Techniques; Intestinal Secretions; Intestine, Small; Male; Microscopy, Electron; Microvilli; Rats; Rats, Inbred Strains	1984
Arachidonic acid cascade and anti-hypoxic drugs. Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:5 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Betamethasone; Chloroquine; Chlorpromazine; Cyclooxygenase Inhibitors; Dinoprost; Epoprostenol; Female; Hypoxia; Imidazoles; Ketoprofen; Mice; Phospholipases A; Phospholipases A2; Prostaglandins F; Thromboxane-A Synthase	1984
Inhibition of lipid peroxidation in muscle homogenates by phospholipase A2 inhibitors. Bioscience reports, 1984, Volume: 4, Issue:7 Topics: Animals; Chloroquine; Chlorpromazine; Dibucaine; Female; Free Radicals; In Vitro Techniques; Iron; Lipid Peroxides; Mice; Muscles; Phospholipases; Phospholipases A; Phospholipases A2; Procaine; Quinacrine; Tetracaine	1984
Effect of drug pretreatment on the metabolic oxidation of chlorpromazine in rat. Pharmacology, 1983, Volume: 27, Issue:3 Topics: Animals; Anthracenes; Chloroquine; Chlorpromazine; Ethanol; Female; Male; Metyrapone; Oxidation-Reduction; Pentobarbital; Premedication; Pyridines; Quinine; Rats; Rats, Inbred Strains; Safrole	1983
Pigmentation of the cornea: a review and classification. Annals of ophthalmology, 1983, Volume: 15, Issue:11 Topics: Adult; Child; Chloroquine; Chlorpromazine; Corneal Diseases; Drug-Related Side Effects and Adverse Reactions; Humans; Pigmentation Disorders	1983
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro. Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:1 Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature	1980
The down-modulation of receptors for phorbol ester tumor promoter in primary epidermal cells. Carcinogenesis, 1982, Volume: 3, Issue:9 Topics: Animals; Arginine; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Chloroquine; Chlorpromazine; Cycloheximide; Epidermis; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Solubility	1982
Studies on the binding of chlorpromazine and chloroquine to melanin in vivo. Biochemical pharmacology, 1981, Jul-01, Volume: 30, Issue:13 Topics: Animals; Calcium; Chemical Phenomena; Chemistry; Chloroquine; Chlorpromazine; Eye; Melanins; Mice; Mice, Inbred C57BL; Sodium	1981
The binding of inorganic and organic cations and H+ to cartilage in vitro. Biochemical pharmacology, 1981, Nov-01, Volume: 30, Issue:21 Topics: Animals; Binding Sites; Cartilage; Cations; Cattle; Chloroquine; Chlorpromazine; Gentamicins; Hexamethonium Compounds; Hydrogen; In Vitro Techniques; Ligands; Nasal Septum; Paraquat	1981
[Sensitivity of albino and black mice to various drugs chemically related to melanins]. Acta poloniae pharmaceutica, 1981, Volume: 38, Issue:4 Topics: Animals; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Male; Mice; Mice, Inbred Strains	1981
Intracellular proteolysis of poliovirus eclipse particles is abortive. The Journal of general virology, 1994, Volume: 75 ( Pt 3) Topics: Amodiaquine; Biological Transport; Chloroquine; Chlorpromazine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lysosomes; Monensin; Poliovirus; Viral Proteins; Virion	1994
Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys. The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:1 Topics: Animals; Aotus trivirgatus; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Cyproheptadine; Disease Models, Animal; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Ketotifen; Malaria, Falciparum; Plasmodium falciparum; Prochlorperazine; Propylamines; Verapamil	1993
Reverse iontophoresis: monitoring prostaglandin E2 associated with cutaneous inflammation in vivo. Experimental dermatology, 1997, Volume: 6, Issue:6 Topics: Amebicides; Anesthetics, Local; Animals; Antiemetics; Arginine Vasopressin; Biological Transport; Blood Flow Velocity; Chloroquine; Chlorpromazine; Dermatitis; Erythema; Guinea Pigs; Iontophoresis; Irritants; Promazine; Prostaglandins E; Skin Ulcer; Sodium Chloride; Tetracaine; Vasoconstrictor Agents	1997
Examination of potential inhibitors of hepatitis A virus uncoating. Intervirology, 1998, Volume: 41, Issue:6 Topics: Animals; Antiviral Agents; Calcium; Cell Line; Chlorocebus aethiops; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Endocytosis; Endosomes; Hepatovirus; Lysosomes; RNA, Viral; Virus Replication	1998
Subcellular membrane impairment and application of phospholipase A2 inhibitors in endotoxic shock. Injury, 1999, Volume: 30, Issue:1 Topics: Animals; Chloroquine; Chlorpromazine; Enzyme Inhibitors; Intracellular Membranes; Membrane Fluidity; Mitochondria; Phospholipases A; Phospholipases A2; Rabbits; Shock, Septic	1999
Pheomelanin as a binding site for drugs and chemicals. Pigment cell research, 1999, Volume: 12, Issue:4 Topics: Albinism; Animals; Autoradiography; Binding Sites; Carbon Radioisotopes; Chloroquine; Chlorpromazine; Clomipramine; Cysteine; Hair Color; Melanins; Mice; Mice, Inbred C57BL; Skin; Thiourea	1999
The effect of binding of chlorpromazine and chloroquine to ion transporting ATPases. Molecular and cellular biochemistry, 1999, Volume: 198, Issue:1-2 Topics: Adenosine Triphosphatases; Animals; Brain; Chloroquine; Chlorpromazine; Circular Dichroism; Fluorescence; Male; Protein Binding; Rats	1999
Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin. Biochemical pharmacology, 2002, Mar-01, Volume: 63, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Chlorpromazine; Drug Resistance; Hemeproteins; Hemin; Parasitic Sensitivity Tests; Phenothiazines; Plasmodium falciparum	2002
[OPHTHALMOLOGICAL COMPLICATIONS OF CERTAIN GENERAL THERAPEUTICS]. Journal de medecine de Lyon, 1964, Mar-05, Volume: 45 Topics: Acetazolamide; Adrenal Cortex Hormones; Anthelmintics; Arsenicals; Barbiturates; Chloroquine; Chlorpromazine; Dinitrophenols; Ophthalmology; Parasympathomimetics; Quinidine; Quinine; Streptomycin; Sulfonamides; Toxicology; Tranquilizing Agents; Vitamin D; Vitamins	1964
FURTHER STUDIES CONCERNING THE ACCUMULATION OF POLYCYCLIC COMPOUNDS ON UVEAL MELANIN. Investigative ophthalmology, 1964, Volume: 3 Topics: Acridines; Adsorption; Animals; Cattle; Chloroquine; Chlorpromazine; Choroid; Melanins; Pharmacology; Phenothiazines; Polycyclic Compounds; Rabbits; Research; Sulfur Isotopes; Uvea	1964
THE REACTION OF UVEAL PIGMENT IN VITRO WITH POLYCYCLIC COMPOUNDS. Investigative ophthalmology, 1964, Volume: 3 Topics: Acridines; Adsorption; Animals; Cattle; Chloroquine; Chlorpromazine; Choroid; Ciliary Body; Hydrogen-Ion Concentration; In Vitro Techniques; Iris; Melanins; Metabolism; Pharmacology; Phenothiazines; Pigments, Biological; Polycyclic Compounds; Retinal Pigments; Sodium Chloride; Trypsin; Uvea	1964
The effect of chlorpromazine, iproniazid, and chloroquine on adrenal ascorbic acid in the rat. Archives internationales de pharmacodynamie et de therapie, 1959, Oct-01, Volume: 122 Topics: Adrenal Cortex; Animals; Ascorbic Acid; Carbohydrate Metabolism; Chloroquine; Chlorpromazine; Iproniazid; Rats	1959
Entry of bovine viral diarrhea virus into ovine cells occurs through clathrin-dependent endocytosis and low pH-dependent fusion. In vitro cellular & developmental biology. Animal, 2010, Volume: 46, Issue:5 Topics: Ammonium Chloride; Animals; beta-Cyclodextrins; Cell Line; Chloroquine; Chlorpromazine; Clathrin; Diarrhea Virus 1, Bovine Viral; Diarrhea Virus 2, Bovine Viral; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Endocytosis; Hydrogen-Ion Concentration; Sheep; Sucrose; Thymus Gland; Virus Internalization	2010
Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents. Environmental and molecular mutagenesis, 2011, Volume: 52, Issue:2 Topics: Amines; Animals; Benzophenones; Bleomycin; Cell Line; Chloroquine; Chlorpromazine; Cricetinae; DNA Damage; Drug Synergism; Gene Conversion; Intercalating Agents; Mefloquine; Mutagenicity Tests; Mutagens; Recombination, Genetic; Saccharomyces cerevisiae; Tamoxifen	2011
[Comparison of mechanisms and cellular uptake of cell-penetrating peptide on different cell lines]. Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:9 Topics: Adsorption; Amiloride; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Exocytosis; Heparin; Humans; Proteoglycans; Temperature; Time Factors	2010
Quantitative comparison of the efficacy of various compounds in lowering intracellular cholesterol levels in Niemann-Pick type C fibroblasts. PloS one, 2012, Volume: 7, Issue:10 Topics: Azacitidine; beta-Cyclodextrins; Cells, Cultured; Child; Child, Preschool; Chloroquine; Chlorpromazine; Cholesterol; Decitabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Intracellular Space; Male; Microscopy, Fluorescence; Mutation; Niemann-Pick Disease, Type C; Panobinostat; Sirolimus; Vorinostat	2012
Inhibiting the clathrin-mediated endocytosis pathway rescues K(IR)2.1 downregulation by pentamidine. Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:2 Topics: Action Potentials; Antiprotozoal Agents; Cell Membrane; Chloroquine; Chlorpromazine; Clathrin-Coated Vesicles; Down-Regulation; Endocytosis; HEK293 Cells; Humans; Hydrazones; Macrolides; Pentamidine; Potassium Channels, Inwardly Rectifying; Protein Transport; Proteolysis	2013
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Chloroquine; Chlorpromazine; Coronavirus 229E, Human; Drug Approval; Hepatocytes; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Loperamide; Lopinavir; Middle East Respiratory Syndrome Coronavirus; Severe acute respiratory syndrome-related coronavirus; Small Molecule Libraries; Vero Cells; Virus Replication	2014
Evaluation of Crimean-Congo hemorrhagic fever virus in vitro inhibition by chloroquine and chlorpromazine, two FDA approved molecules. Antiviral research, 2015, Volume: 118 Topics: Animals; Antiviral Agents; Cell Line; Chloroquine; Chlorpromazine; Drug Repositioning; Drug Synergism; Hemorrhagic Fever Virus, Crimean-Congo; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Ribavirin; Virus Internalization	2015
Lysosomotropic drugs enhance pro-inflammatory responses to IL-1β in macrophages by inhibiting internalization of the IL-1 receptor. Biochemical pharmacology, 2020, Volume: 175 Topics: Autophagy; Cell Culture Techniques; Cell Survival; Chloroquine; Chlorpromazine; Endocytosis; Fluoxetine; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Lysosomes; Macrophages; Receptors, Interleukin-1; Signal Transduction; THP-1 Cells	2020
Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 Journal of virology, 2020, 10-14, Volume: 94, Issue:21 Topics: A549 Cells; Animals; Antiviral Agents; Betacoronavirus; Chloroquine; Chlorpromazine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Evaluation, Preclinical; Humans; Middle East Respiratory Syndrome Coronavirus; Pandemics; Pneumonia, Viral; SARS-CoV-2; Treatment Outcome; United States; United States Food and Drug Administration; Virus Replication	2020