Compounds > chlorpromazine

chlorpromazine and carbidopa

chlorpromazine has been researched along with carbidopa in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (35.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (5.00)	29.6817
2010's	11 (55.00)	24.3611
2020's	1 (5.00)	2.80

Authors

Authors	Studies
Bellman, K; Knegtel, RM; Settimo, L	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Caine, E; Carter, AC; Ebert, M; Kartzinel, R	1
Bigelow, LB; Gillin, JC; Walls, P; Wyatt, RJ	1
Antonaccio, MJ; Robson, RD	1
Sethy, VH; Van Woert, MH	2
Duvoisin, RC; Marsden, CD	1
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN	1
Khatoon, H; Mirza, T; Najam, R; Sikandar, B	1
Ikram, R; Riaz, B; Sikandar, B	1
Khan, SS; Mirza, T; Naeem, S; Najam, R; Sikandar, B	1
Balogun, CI; Fatoki, AM; Oladimeji, S; Olofinnade, AT; Onaolapo, AY; Onaolapo, OJ; Onaolapo, TM	1

Reviews

1 review(s) available for chlorpromazine and carbidopa

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for chlorpromazine and carbidopa

Article	Year
Neuroendocrine function in Huntington's disease: dopaminergic regulation of prolactin release. Life sciences, 1978, Volume: 22, Issue:10 Topics: Adult; Bromocriptine; Carbidopa; Chlorpromazine; Dopamine; Female; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Placebos; Prolactin; Time Factors	1978
Clinical effects of L-5-hydroxytryptophan administration in chronic schizophrenic patients. Biological psychiatry, 1979, Volume: 14, Issue:1 Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia	1979

Other Studies

17 other study(ies) available for chlorpromazine and carbidopa

Article	Year
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
L-dopa hypotension in dogs: evidence for mediation through 5-HT release. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Carbidopa; Chlorpromazine; Depression, Chemical; Dogs; Drug Interactions; Female; Fenclonine; Haloperidol; Heart Rate; Levodopa; Male; Methysergide; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Serotonin; Time Factors; Yohimbine	1974
Regulation of striatal acetylcholine concentration by dopamine receptors. Nature, 1974, Oct-11, Volume: 251, Issue:5475 Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Pimozide; Rats; Receptors, Adrenergic	1974
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi. Brain research, 1974, May-10, Volume: 71, Issue:1 Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine	1974
Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists. Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:1 Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Brain Stem; Carbidopa; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dihydroxyphenylalanine; Dioxoles; Dopamine; Drug Synergism; Haloperidol; Hippocampus; Hypothalamus; Male; Pimozide; Piperazines; Pyrimidines; Rats; Receptors, Drug; Thalamus; Time Factors	1974
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels. Journal of neural transmission, 1982, Volume: 53, Issue:1 Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan	1982
Beneficial anti-Parkinson effects of camel milk in Chlorpromazineinduced animal model: Behavioural and histopathological study. Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:5 Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain; Camelus; Carbidopa; Catalepsy; Chlorpromazine; Drug Combinations; Female; Levodopa; Male; Milk; Parkinsonian Disorders; Rats, Wistar; Time Factors	2016
Anticataleptic activity of Zamzam water in chlorpromazine induced animal model of Parkinson disease. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:2 Topics: Animals; Brain; Carbidopa; Catalepsy; Chlorpromazine; Disease Models, Animal; Drug Combinations; Hydrogen-Ion Concentration; Levodopa; Parkinsonian Disorders; Rats; Water	2018
Neuroprotective effect of diclofenac on chlorpromazine induced catalepsy in rats. Metabolic brain disease, 2019, Volume: 34, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Catalepsy; Chlorpromazine; Corpus Striatum; Diclofenac; Dopamine; Female; Levodopa; Male; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar	2019
An Evaluation of the Effects of Pyridoxal Phosphate in Chlorpromazineinduced Parkinsonism using Mice. Central nervous system agents in medicinal chemistry, 2020, Volume: 20, Issue:1 Topics: Animals; Antioxidants; Antiparkinson Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Carbidopa; Chlorpromazine; Diet; Drug Combinations; Eating; Grooming; Levodopa; Lipid Peroxidation; Mice; Motor Activity; Parkinson Disease, Secondary; Pyridoxal Phosphate	2020