chlorpromazine and carbamazepine

chlorpromazine has been researched along with carbamazepine in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199031 (39.24)18.7374
1990's7 (8.86)18.2507
2000's20 (25.32)29.6817
2010's20 (25.32)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Hino, K; Karasawa, T; Masuda, Y; Nagai, Y; Oka, M; Uno, H1
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Andricopulo, AD; Moda, TL; Montanari, CA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Sen, S; Sinha, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Steele, DE1
Hazama, H; Inanaga, K; Mori, A; Okuma, T; Otsuki, S; Sarai, K; Takahashi, R; Watanabe, M1
Vol'f, MSh1
Oettinger, L1
Fletcher, HP; Schnell, RC; Wannarka, GL1
Wada, JA1
Kinawi, A; Teller, C1
Kinawi, A; Min, K1
Aznar Reig, A; Bolaños Díaz, A; De la Vega Vázquez, JM; Fajardo Gálvez, J; Holgado Silva, C1
Dolan, JD; Kamil, R1
Borchert, HH; Göckeritz, W1
Brown, D; Cookson, J; Silverstone, T1
Samanin, R; Tullii, M; Vezzani, A; Wu, HQ1
Grossi, E; Lazzerini, F; Lenzi, A; Massimetti, G; Placidi, GF1
Lippmann, S; Pary, R; Tobias, CR; Turns, DM1
Kutt, H; Penry, JK1
Mullan, S1
Lalla, M; Virolainen, M1
Wieck, HH1
Gazengel, J; Lhermitte, F; Marteau, R; Peterfalvi, M; Serdaru, M1
Trautmann, A1
Post, RM1
Hertrich, O1
Okuma, T2
Singh, NN; Winton, AS1
Hershkowitz, N; Mahany, TM; Raines, A1
Aun, R; de Almeida, GM; de Oliveira Júnior, JO; Segushi, HH; Teixeira, MJ1
Greim, H1
Post, RM; Silberman, EK1
Hellawell, DJ; Wright, S; Young, AW1
Dehpour, AR; Farahani, M; Farsam, H; Sadeghipour-Roudsari, HR; Shokrgozar, AA1
Dromerick, AW; Kumar, A1
Alexishvili, MM; Makharadze, TG; Okujava, VM; Rukhadze, MD; Sebiskveradze, MV; Tsagareli, SK1
Hardy-Baylé, MC1
Aina, OF; Morakinyo, O1
Kanba, S; Miyaoka, H; Nakaki, T; Shintani, F; Suzuki, E1
Girimaji, SC; Jairam, R; Seshadri, SP; Srinath, S1
Dzidziguri, DV; Giorgobiani, NM; Kerkenjia, SM; Rukhadze, MD1
Halwachs, S; Honscha, W; Kneuer, C1
Brodaty, H; Cumming, R; Forrester, L; Grayson, D; Hollis, J; Touyz, S2
Ahn, YM; Bae, HJ; Eun, JW; Jin, CY; Kang, HJ; Kim, H; Kim, HS; Lee, JY; Nam, SW; Park, SJ; Park, WS; Shen, Q; Shin, WC; Yang, HD; You, JS1
Calimli, MH; Kanberoğlu, GS; Karaman, M; Türkan, F1

Reviews

7 review(s) available for chlorpromazine and carbamazepine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pediatric psychopharmacology. A review with special reference to deanol.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Adolescent; Adult; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; Chlorpromazine; Deanol; Epilepsy; Ethanolamines; Heart Rate; Humans; Learning; Methylphenidate; Pemoline; Phenytoin; Rats; Syndrome; Thioridazine

1977
Pharmacological prophylaxis in the kindling model of epilepsy.
    Archives of neurology, 1977, Volume: 34, Issue:7

    Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid

1977
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
Use of the anticonvulsant carbamazepine in primary and secondary affective illness: clinical and theoretical implications.
    Psychological medicine, 1982, Volume: 12, Issue:4

    Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Clinical Trials as Topic; gamma-Aminobutyric Acid; Humans; Lithium; Lithium Carbonate; Psychotic Disorders; Psychotropic Drugs

1982
[Enzyme induction in the liver changes drug activity].
    Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20

    Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors

1980

Trials

6 trial(s) available for chlorpromazine and carbamazepine

ArticleYear
Comparison of the antimanic efficacy of carbamazepine and chlorpromazine: a double-blind controlled study.
    Psychopharmacology, 1979, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Carbamazepine; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Humans; Middle Aged; Time Factors

1979
Carbamazepine compared to haloperidol in acute mania.
    International clinical psychopharmacology, 1989, Volume: 4, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Bipolar Disorder; Carbamazepine; Chlorpromazine; Female; Haloperidol; Humans; Leukocyte Count; Male; Middle Aged; Procyclidine; Psychiatric Status Rating Scales

1989
Use of carbamazepine in acute psychosis: a controlled study.
    The Journal of international medical research, 1986, Volume: 14, Issue:2

    Topics: Acute Disease; Adult; Carbamazepine; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Random Allocation

1986
Use of the anticonvulsant carbamazepine in primary and secondary affective illness: clinical and theoretical implications.
    Psychological medicine, 1982, Volume: 12, Issue:4

    Topics: Affective Disorders, Psychotic; Animals; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Clinical Trials as Topic; gamma-Aminobutyric Acid; Humans; Lithium; Lithium Carbonate; Psychotic Disorders; Psychotropic Drugs

1982
Therapeutic and prophylactic effects of carbamazepine in bipolar disorders.
    The Psychiatric clinics of North America, 1983, Volume: 6, Issue:1

    Topics: Adult; Bipolar Disorder; Carbamazepine; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Male; Middle Aged

1983
A prospective 4-5 year follow-up of juvenile onset bipolar disorder.
    Bipolar disorders, 2004, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Female; Follow-Up Studies; Haloperidol; Humans; Imipramine; Lithium Carbonate; Male; Phenotype; Prospective Studies; Recovery of Function; Risperidone; Secondary Prevention; Severity of Illness Index; Valproic Acid

2004

Other Studies

67 other study(ies) available for chlorpromazine and carbamazepine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Body Temperature Regulation; Brain; Electroshock; Exploratory Behavior; Homovanillic Acid; Hypothermia; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Seizures; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2003
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Tic doloureux.
    Lancet (London, England), 1975, Aug-30, Volume: 2, Issue:7931

    Topics: Carbamazepine; Chlorpromazine; Humans; Male; Phenytoin; Trigeminal Neuralgia

1975
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Drug Synergism; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Glycerol; Humans; Methotrimeprazine; Mice; Pentylenetetrazole; Phenothiazines; Promethazine; Psychotic Disorders; Seizures; Thioridazine

1975
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine; Hyperglycemia; Imipramine; Insulin; Islets of Langerhans; Male; Mice; Promazine

1979
[Determination of drug-albumin binding in buffered bovine serum albumin solutions applying a modified ultrafiltration process (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:10

    Topics: Animals; Carbamazepine; Cattle; Chlorpromazine; Methods; Pharmaceutical Preparations; Phenobarbital; Phenprocoumon; Protein Binding; Serum Albumin, Bovine; Ultrafiltration

1979
[Application of hplc-techniques to gel filtration in the determination of drug albumin binding (author's transl)].
    Biomedizinische Technik. Biomedical engineering, 1978, Volume: 23, Issue:3

    Topics: Animals; Carbamazepine; Cattle; Chlorpromazine; Chromatography, Gel; Chromatography, High Pressure Liquid; Phenobarbital; Protein Binding; Serum Albumin, Bovine

1978
[Diabetes insipidus. Clinico-pharmalogical correlations and their therapeutic results with various substances].
    Revista clinica espanola, 1978, Feb-28, Volume: 148, Issue:4

    Topics: Carbamazepine; Chlorpromazine; Clofibrate; Diabetes Insipidus; Diuresis; Drug Evaluation; Drug Therapy, Combination; Humans; Osmolar Concentration; Vasopressins

1978
Atypical affective disorder with episodic dyscontrol: a case of von Economo's disease (encephalitis lethargica).
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37, Issue:2

    Topics: Adult; Antipsychotic Agents; Carbamazepine; Chlorpromazine; Chronic Disease; Electroencephalography; Encephalitis, Arbovirus; Follow-Up Studies; Humans; Lorazepam; Male; Mood Disorders; Sexual Behavior

1992
[The effect of chlorpromazine and carbamazepine on diagnostically relevant liver enzymes].
    Die Pharmazie, 1990, Volume: 45, Issue:8

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbamazepine; Chlorpromazine; Glutamate Dehydrogenase; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Rats; Rats, Inbred Strains

1990
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid

1986
[Drug selection after overdose recovery: carbamazepine or lithium].
    The Journal of the Kentucky Medical Association, 1987, Volume: 85, Issue:1

    Topics: Adult; Carbamazepine; Chlorpromazine; Humans; Lithium; Male; Risk; Suicide Prevention

1987
Surgical management of pain in cancer of the head and neck.
    The Surgical clinics of North America, 1973, Volume: 53, Issue:1

    Topics: Alcohols; Autonomic Nerve Block; Carbamazepine; Chlorpromazine; Cranial Nerves; Gastrostomy; Head; Head and Neck Neoplasms; Humans; Medulla Oblongata; Methadone; Neck; Neoplasms; Pain; Sensation; Spinal Cord; Spinal Fusion; Tracheotomy; Trigeminal Nerve

1973
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
    International archives of allergy and applied immunology, 1974, Volume: 46, Issue:2

    Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocytes; Nitrofurantoin; Phenytoin; Prednisone; Stevens-Johnson Syndrome; Sulfonamides; Thymidine; Trimethoprim; Tritium; Urticaria

1974
[Headache. Diagnosis and therapy in general practice].
    Fortschritte der Medizin, 1974, Jun-13, Volume: 92, Issue:17

    Topics: Carbamazepine; Chlorpromazine; Depression; Ergotamine; Giant Cell Arteritis; Headache; Humans; Migraine Disorders; Neuralgia; Promethazine; Trigeminal Neuralgia

1974
[Pharmacological analysis of a case of postanoxic intention and action myoclonus].
    Revue neurologique, 1971, Volume: 124, Issue:1

    Topics: 5-Hydroxytryptophan; Alcohols; Anticonvulsants; Benzoates; Carbamazepine; Chlorpromazine; Diazepam; Dibenzazepines; Dopamine; Ergotamine; Female; Haloperidol; Humans; Hypoxia, Brain; Methotrimeprazine; Methyldopa; Methysergide; Middle Aged; Myoclonus; Norepinephrine; Phenobarbital; Pyrrolidines; Stereotaxic Techniques; Sulfonamides; Tranquilizing Agents; Trihexyphenidyl

1971
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
[Ataractic treatment in psychiatry and general medicine. Overview of preparations, 2].
    Fortschritte der Medizin, 1983, Jun-02, Volume: 101, Issue:21

    Topics: Bromazepam; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Humans; Perphenazine; Psychophysiologic Disorders; Psychotic Disorders; Schizophrenia; Temazepam; Tranquilizing Agents

1983
Behavioral monitoring of pharmacological interventions for self-injury.
    Applied research in mental retardation, 1984, Volume: 5, Issue:1

    Topics: Adolescent; Behavior; Behavior Therapy; Carbamazepine; Chlorpromazine; Circadian Rhythm; Humans; Intellectual Disability; Male; Overlearning; Self Mutilation; Thioridazine

1984
Effects of carbamazepine on muscle tone in the decerebrate cat.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Animals; Carbamazepine; Cats; Chlorpromazine; Decerebrate State; Electric Stimulation; Female; Male; Motor Neurons; Muscle Contraction; Muscle Relaxation

1983
[Genitofemoral neuralgia].
    Revista do Hospital das Clinicas, 1982, Volume: 37, Issue:5

    Topics: Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Chlorpromazine; Female; Humans; Lumbosacral Plexus; Male; Middle Aged; Neuralgia

1982
Differential sensitivity to the effects of psychotropic drugs: psychotics vs normals; Asian vs Western populations.
    Folia psychiatrica et neurologica japonica, 1981, Volume: 35, Issue:1

    Topics: Bipolar Disorder; Carbamazepine; Chlorpromazine; Cross-Cultural Comparison; Dose-Response Relationship, Drug; Drug Tolerance; Electroencephalography; Humans; Imipramine; Japan; Psychotropic Drugs; Schizophrenia

1981
The march of symptoms in a psychotic decompensation. Case report and theoretical implications.
    The Journal of nervous and mental disease, 1980, Volume: 168, Issue:2

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Behavior; Carbamazepine; Chlorpromazine; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Psychotic Disorders; Schizophrenia

1980
Sequential Cotard and Capgras delusions.
    The British journal of clinical psychology, 1993, Volume: 32, Issue:3

    Topics: Adult; Brain; Capgras Syndrome; Carbamazepine; Chlorpromazine; Delusions; Depressive Disorder; Electroencephalography; Humans; Male; Memory Disorders; Perphenazine; Psychiatric Status Rating Scales

1993
Decrease in erythrocyte:plasma lithium ratio by concurrent administration of psychotropic drugs and lithium in mice.
    General pharmacology, 1998, Volume: 31, Issue:1

    Topics: Animals; Antipsychotic Agents; Carbamazepine; Chlorpromazine; Drug Therapy, Combination; Erythrocytes; Haloperidol; Imipramine; Lithium; Male; Mice; Prospective Studies

1998
Intractable hiccups during stroke rehabilitation.
    Archives of physical medicine and rehabilitation, 1998, Volume: 79, Issue:6

    Topics: Aged; Baclofen; Carbamazepine; Cerebral Infarction; Cerebrovascular Disorders; Chlorpromazine; Dopamine Antagonists; Haloperidol; Hiccup; Humans; Incidence; Male; Middle Aged; Muscle Relaxants, Central; Pons; Retrospective Studies

1998
Interaction of carbamazepine and chlorpromazine in rabbits.
    Biomedical chromatography : BMC, 1999, Volume: 13, Issue:7

    Topics: Animals; Anticonvulsants; Carbamazepine; Chlorpromazine; Chromatography, High Pressure Liquid; Drug Interactions; Rabbits

1999
[Manic syndrome: diagnostic trends and principles of treatment].
    La Revue du praticien, 1998, Apr-01, Volume: 48, Issue:7

    Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnosis, Differential; Haloperidol; Hospitalization; Humans; Iatrogenic Disease; Lithium; Neurocognitive Disorders; Schizophrenia; Syndrome; Time Factors; Valproic Acid

1998
Landau-Kleffner syndrome (acquired epileptic aphasia) in a Nigerian child.
    The Nigerian postgraduate medical journal, 2002, Volume: 9, Issue:1

    Topics: Anticonvulsants; Antipsychotic Agents; Carbamazepine; Child, Preschool; Chlorpromazine; Drug Therapy, Combination; Electroencephalography; Female; Humans; Landau-Kleffner Syndrome; Nigeria

2002
Antipsychotic, antidepressant, anxiolytic, and anticonvulsant drugs induce type II nitric oxide synthase mRNA in rat brain.
    Neuroscience letters, 2002, Nov-29, Volume: 333, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Brain; Carbamazepine; Chlorpromazine; Diazepam; Fluvoxamine; Gene Expression; Haloperidol; Isoxazoles; Lithium; Male; Maprotiline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Zonisamide

2002
The study of growth inhibitive protein factor by various mode of HPLC and estimation of its binding with drugs.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:1

    Topics: Animals; Brain Chemistry; Carbamazepine; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Growth Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Nerve Tissue Proteins; Phenobarbital; Protein Binding; Rats; Serum Albumin; Spectrophotometry, Ultraviolet

2005
Downregulation of the reduced folate carrier transport activity by phenobarbital-type cytochrome P450 inducers and protein kinase C activators.
    Biochimica et biophysica acta, 2007, Volume: 1768, Issue:6

    Topics: Animals; Carbamazepine; Carrier Proteins; Cell Line, Tumor; Chlorpromazine; Clotrimazole; Cytochrome P-450 Enzyme System; DNA Primers; Down-Regulation; Enzyme Activators; Folate Receptors, GPI-Anchored; Immunohistochemistry; Okadaic Acid; Protein Kinase C; Rats; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction

2007
Risk of death associated with antipsychotic drug dispensing in residential aged care facilities.
    The Australian and New Zealand journal of psychiatry, 2007, Volume: 41, Issue:9

    Topics: Aged; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Comorbidity; Cross-Sectional Studies; Death, Sudden; Female; Haloperidol; Homes for the Aged; Humans; Male; Nursing Homes; Olanzapine; Risk; Valproic Acid; Veterans

2007
Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2007, Volume: 15, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Carbamazepine; Cause of Death; Chlorpromazine; Cohort Studies; Dementia; Female; Haloperidol; Humans; Male; Mortality; Olanzapine; Proportional Hazards Models; Retrospective Studies; Risk; Risk Factors; Survival Rate; Valproic Acid; Veterans; Widowhood

2007
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:2

    Topics: Animals; Biomarkers; Carbamazepine; Chemical and Drug Induced Liver Injury; Chlorpromazine; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enalapril; Gene Expression; Liver; Male; Oligonucleotide Array Sequence Analysis; Proteomics; Pyrazinamide; Ranitidine; Rats; Rats, Sprague-Dawley; Transcriptome

2015
Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on glutathione S-transferase, cholinesterases enzymes and molecular docking studies.
    Journal of biomolecular structure & dynamics, 2021, Volume: 39, Issue:9

    Topics: Acetylcholinesterase; Carbamazepine; Chlorpromazine; Cholinesterase Inhibitors; Glutathione Transferase; Isoproterenol; Molecular Docking Simulation; Pharmaceutical Preparations; Tamoxifen

2021