chlorpromazine has been researched along with caffeine in 175 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 123 (70.29) | 18.7374 |
1990's | 5 (2.86) | 18.2507 |
2000's | 19 (10.86) | 29.6817 |
2010's | 25 (14.29) | 24.3611 |
2020's | 3 (1.71) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L | 1 |
Butler, DE; Marriott, JG; Poschel, BP | 1 |
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
Sen, S; Sinha, N | 1 |
Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, ZF; Huang, SL; Huang, ZS; Liang, H; Qin, JK; Tang, H; Zhao, HT; Zhao, LZ; Zhong, SM | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Chen, ZF; Liang, H; Tang, H; Wang, ZY; Zhao, HT; Zhong, SM | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Jiang, N; Kong, LY; Lan, JS; Li, ZR; Wang, KD; Wang, X; Xie, SS; Yu, W | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Chen, W; Huangli, Y; Qin, J; Shen, Y; Tang, H; Wang, L; Wei, S | 1 |
Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
Cheng, M; Guo, J; Jiang, N; Li, Q; Liang, N; Liu, J; Nong, X; Pang, C; Qin, Y; Tang, C; Tang, W; Xie, SS; Zhang, Z | 1 |
Cheng, M; Fang, Y; Guo, J; Jin, Y; Liu, J; Wan, Y; Wang, R; Xie, SS; Zhang, Z; Zhou, W | 1 |
Hanson, HM; Ivester, CA; Morton, BR | 1 |
Fujiwara, M; Oishi, R; Razzak, A; Ueki, S | 1 |
Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
Gourevitch, A; Yanev, S | 1 |
Jhamandas, K; Sawynok, J; Sutak, M | 1 |
Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW | 1 |
Feller, K; Graupner, K; Kálmán, E; von Littrow, C | 1 |
Kalachev, BP | 1 |
Bolden, TE; Lemeh, DH; Seibert, W; Stewart, EB | 1 |
Buczko, W; Moniuszko-Jakoniuk, J | 1 |
Fukushima, M; Shibata, M | 1 |
Matkó, I; Petri, G; Szenohradszky, J; Tárnoky, K | 1 |
Kenunen, OG; Kozlovskiĭ, VL | 1 |
Lialiaris, T; Mourelatos, D; Pantazaki, A; Sivridis, E | 1 |
Rudas, N; Tondo, L | 1 |
Grigorus, AG; Navakatikjan, AO | 1 |
Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F | 1 |
Glatte, P; Osieka, R; Schmidt, CG | 1 |
Kurebayashi, N; Ogawa, Y | 1 |
Jauchem, JR | 1 |
Phillis, JW | 1 |
Dozi-Vassiliades, J; Lialiaris, T; Mourelatos, D | 1 |
Goldberg, SR; Katz, JL | 1 |
Glatte, P; Osieka, R; Pannenbäcker, R; Schmidt, CG | 1 |
Ashoori, F; Takai, A; Tomita, T | 1 |
Matsubara, S; Omori, T | 1 |
Bounameaux, Y | 1 |
Ferrini, R; Miragoli, G | 1 |
Färber, G; Fraling, F; Herz, A; Niedner, I | 1 |
Molnár, J; Prágai, B | 1 |
Amiragova, MG; Arkhangel'skaia, MI; Svirskaia, RI | 1 |
Bînzaru, T; Mihalaş, GI; Nagy, I; Plauchithiu, M; Rottenberg, F | 1 |
Carvalho, AP; Madeira, VM | 1 |
Bishun, NP; Lloyd, N; Mills, J; Parke, DV; Raven, RW; Williams, DC | 1 |
Greengard, P; Quinn, GP; Reid, MB | 1 |
Gibson, W; Jessup, S; Ramwell, P; Shaw, J | 1 |
Giurgea, CE; Moyersoons, FE | 1 |
Galzigna, L | 1 |
Mlejnkova, M; Rysánek, K; Spánkova, H; Synek, P | 1 |
Beyrich, T; Schleuder, M | 1 |
Takaori, S; Tanabe, K | 1 |
Boissier, JR; Larousse, C; Simon, P; Villeneuve, A | 1 |
Chiba, S; Nagawa, Y; Yui, T | 1 |
Frank, GB; Jhamandas, K | 1 |
Hata, T; Kita, T; Murakami, T | 1 |
Ditzler, W; Plotnikoff, N; Will, F | 1 |
Izquierdo, I | 1 |
Doctor, RB; Jindal, MN; Kelkar, VV | 1 |
Andersson, KE | 1 |
Batra, S | 1 |
Kulikov, MA; Zlatin, RS | 1 |
Borowitz, JL; Miya, TS; Rahwan, RG | 1 |
Billets, S; Carruth, J; Einolf, N; Fenselau, C; Ward, R | 1 |
Cohen, MH | 1 |
Antunes-Madeira, MC; Madeira, VM | 1 |
Gordon, JL | 1 |
Endo, T | 1 |
Bass, WC; Brown, H | 1 |
Deneau, G; Seevers, MH; Yanagita, T | 1 |
Mason, RG; Read, MS; Saba, SR; Shermer, RW | 1 |
Nakano, M | 1 |
Ban, TA; Lehmann, HE | 1 |
Hecht, K; Treptow, K | 1 |
Hecht, K; Peschel, M; Treptow, K | 1 |
Filipescu, A; Spirescu, J | 1 |
Bapat, SK; Dhawn, BN; Saxena, VC | 1 |
Saito, H; Takagi, K; Watanabe, M | 1 |
Hecht, K; Hecht, T; Treptow, K | 1 |
Balwani, JH; Mardikar, BR; Srinivasan, S | 1 |
von Albert, HH | 1 |
Fairhurst, AS; Hasselbach, W | 1 |
Markovich, VV; Ostrovskaia, RU | 1 |
Nieschulz, O | 2 |
Shliafer, TP | 1 |
Molinengo, L; Ricci-Gamalero, S | 1 |
Senault, B | 1 |
Barbaz, BS; Bernard, PS; Chernov, HI; DeStevens, G; Partyka, DA; Wilson, DE | 1 |
Dítĕ, P; Krízala, JF; Krupar, V; Sita, F | 1 |
Schubert, B | 1 |
Laplace, JP; Ruckebusch, Y | 1 |
Preibisch-Effenberger, R; Schmidt, V | 1 |
Lugovskiĭ, BK | 1 |
Burgison, RM; Dietz, AJ | 1 |
Hecht, K; Hecht, T; Poppei, M; Treptow, K | 1 |
Birzis, L; Tachibana, S | 1 |
Bättig, K; Wanner, HU | 1 |
Knothe, J; Preibischèffenberger, R | 1 |
Gen, MC; Valdman, AV | 1 |
Collins, RJ; Simonton, VR | 1 |
Babbini, M; Cestari, A; De Marchi, F; Graziani, G | 1 |
Caldwell, P; Emmett-Oglesby, MW; Spencer, DG | 1 |
Hagiwara, Y; Suzuki, Y; Taguchi, K | 1 |
Cassone, MC; Fundarò, A; Molinengo, L | 1 |
Emley, GS; Hutchinson, RR | 1 |
Jones, RS; Olpe, HR; Steinmann, MW | 1 |
Sporn, P | 1 |
Cohen, MH; Schoenfeld, D; Wolter, J | 1 |
Chaput de Saintonge, DM; Hong, CY; Turner, P | 1 |
Kuribara, H | 1 |
BLOUGH, DS | 1 |
BARRY, H; ZIMBARDO, PG | 1 |
HIRASHIMA, T | 1 |
HIMWICH, HE; STEINER, WG | 1 |
FRUTTERO, F; HAHN, R; SCARZELLA, R | 1 |
BARGIEL, Z; KADZIELA, W | 1 |
BOHDANECKY, Z; NECINA, J | 1 |
STAIB, AH | 1 |
HUGGINS, CG; SMITH, CM; WALASZEK, EJ | 1 |
LYNN, R | 1 |
GRUNDMAN, M; LENFELD, J; SLADKOVA, O | 1 |
WHITE, RP | 1 |
YAMAMOTO, H | 1 |
GUSHANSKII, EL | 1 |
TURI, P | 1 |
BESSIN, P; BOISSIER, JR; DUMONT, C | 1 |
TEUCHMANN, JK; WIGLUSZ, Z | 1 |
FORNEY, RB; HUGHES, FW; KHAN, AU | 1 |
CROMLEY, WH; EBY, RZ; FELLOWS, EJ; FOWLER, PJ; PAULS, JF; TEDESCHI, DH | 1 |
BARRY, H; MILLER, NE | 1 |
GOLDSTEIN, L; MURPHREE, HB; PFEIFFER, CC; SUGERMAN, AA | 1 |
RUDOLPH, AS; SEWELL, HH; WHITE, RP | 1 |
KURYSHEVA, KA; POLUSHCHEV, FN | 1 |
HIRASHIMA, T; HIROTA, K; MAKINO, H; NAKAMURA, T; TAKAHASHI, Y; YAMAMOTO, K | 1 |
Lialiaris, TS; Mourelatos, C; Papachristou, F; Simopoulou, M | 1 |
Nakagawa, T; Nishi, K; Takase, I; Yamamoto, Y | 1 |
Bankstahl, JP; Bankstahl, M; Bloms-Funke, P; Löscher, W | 1 |
Harris, G; Landesmann, B; Mennecozzi, M; Palosaari, T; Whelan, M | 1 |
Kobayashi, K; Matsushita, S; Murata, T; Shimizu, N | 1 |
4 review(s) available for chlorpromazine and caffeine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Effects of drugs on thermal responses to microwaves.
Topics: Adrenergic beta-Antagonists; Analgesics; Anesthetics; Animals; Bemegride; Body Temperature; Caffeine; Cardiac Glycosides; Chlorpromazine; Cholinesterase Inhibitors; Doxapram; Glucocorticoids; Hexamethonium; Hexamethonium Compounds; Microwaves; Nicotine; Nikethamide; Parasympatholytics; Parasympathomimetics; Pentylenetetrazole; Serotonin; Sympathomimetics; Vitamins | 1985 |
Chromosome damage induced by chemicals.
Topics: Antineoplastic Agents; Aspirin; Benzene; Caffeine; Chloramphenicol; Chlorine; Chlorpromazine; Chromosome Aberrations; Chromosomes; Colchicine; Contraceptives, Oral; Cyclamates; Diazepam; Dibenzazepines; Drug Evaluation; Ethanol; Humans; Hydroxylamines; Lithium; Lymphocyte Culture Test, Mixed; Lysergic Acid Diethylamide; Nicotine; Organophosphorus Compounds; Ozone; Pesticides; Phenylbutazone | 1973 |
RUSSIAN THEORY AND RESEARCH ON SCHIZOPHRENIA.
Topics: Amobarbital; Bromides; Caffeine; Cerebral Cortex; Chlorpromazine; Conditioning, Psychological; Convulsive Therapy; Electroconvulsive Therapy; Electroencephalography; Humans; Insulin; Orientation; Psychological Tests; Research; Russia; Schizophrenia; Sleep; Sodium; Sympathetic Nervous System; USSR | 1963 |
3 trial(s) available for chlorpromazine and caffeine
Article | Year |
---|---|
Effects of psychoactive drugs on conflict avoidance behavior in human subjects.
Topics: Adolescent; Adult; Amobarbital; Avoidance Learning; Caffeine; Child; Chlordiazepoxide; Chlorpromazine; Conflict, Psychological; Electroshock; Female; Haloperidol; Humans; Male; Meprobamate; Methamphetamine; Neurotic Disorders; Pentylenetetrazole; Perphenazine; Placebos; Tranquilizing Agents | 1971 |
Effect of four centrally acting drugs on handwriting.
Topics: Caffeine; Chlorpromazine; Female; Handwriting; Humans; Male; Methamphetamine; Phenobarbital; Placebos | 1969 |
Randomized trial of chlorpromazine, caffeine, and methyl-CCNU in disseminated melanoma.
Topics: Caffeine; Chlorpromazine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Melanoma; Nitrosourea Compounds; Semustine; Time Factors; Vomiting | 1980 |
168 other study(ies) available for chlorpromazine and caffeine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Humans; Male; Mice; Mice, Inbred Strains; Pyrrolidines; Structure-Activity Relationship | 1984 |
Cognition-activating properties of 3-(Aryloxy)pyridines.
Topics: Animals; Cognition; Dose-Response Relationship, Drug; Male; Mice; Psychotropic Drugs; Pyridines; Structure-Activity Relationship | 1981 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Aporphines; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Models, Biological; Tacrine | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Membranes, Artificial; Models, Molecular; Molecular Structure; Permeability; Protein Binding | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzopyrans; Blood-Brain Barrier; Brain; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Coumarins; Drug Design; Erythrocytes; Humans; Kinetics; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Piperazines; Tacrine | 2015 |
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Autophagy; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Cell Survival; Clorgyline; Dose-Response Relationship, Drug; Drug Design; Humans; Indans; Male; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzothiazoles; Benzylamines; Biphenyl Compounds; Butyrylcholinesterase; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Horses; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuroprotective Agents; Picrates; Rats; Structure-Activity Relationship; Sulfonic Acids; Xanthones | 2021 |
Nicotine self-administration in rats.
Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1979 |
Possible involvement of a central noradrenergic system in automutilation induced by clonidine in mice.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Caffeine; Catecholamines; Chlorpromazine; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Humans; Levodopa; Male; Methamphetamine; Methyltyrosines; Mice; Phenoxybenzamine; Phentolamine; Reserpine; Self Mutilation; Sympathetic Nervous System; Theophylline | 1977 |
Influence of injected psychoactive drugs on cyclic AMP levels in mouse brain and lung following microwave irradiation.
Topics: Adenylyl Cyclases; Amitriptyline; Animals; Brain Chemistry; Caffeine; Chlorpromazine; Cyclic AMP; Dextroamphetamine; Lung; Lysergic Acid Diethylamide; Male; Methyltyrosines; Mice; Microwaves; p-Hydroxyamphetamine; Papaverine; Pargyline; Phosphoric Diester Hydrolases; Psychotropic Drugs; Reserpine | 1977 |
Motor estimation of short time intervals under the effect of some psychotropic drugs.
Topics: Adult; Amphetamine; Caffeine; Chlorpromazine; Diazepam; Humans; Phenobarbital; Psychotropic Drugs; Reaction Time; Task Performance and Analysis; Time Perception | 1979 |
Antagonism of morphine action on brain acetylcholine release by methylxanthines and calcium.
Topics: Acetylcholine; Animals; Brain; Caffeine; Calcium; Chlorpromazine; Morphine; Rats; Theophylline; Xanthines | 1978 |
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Semustine | 1978 |
[The influence of centrally acting drugs on flicker fusion frequency].
Topics: Caffeine; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Flicker Fusion; Humans; Meprobamate; Psychotropic Drugs | 1975 |
Interactions of alcohol with drugs.
Topics: Amphetamines; Caffeine; Chlorpromazine; Diazepam; Disulfiram; Drug Interactions; Ethanol; Humans | 1977 |
[Assessment of the effectiveness of autogenic training in the complex treatment of neurotic and psychopathic states].
Topics: Adolescent; Adult; Amitriptyline; Amobarbital; Antisocial Personality Disorder; Autogenic Training; Caffeine; Chlorpromazine; Drug Combinations; Female; Humans; Hysteria; Male; Middle Aged; Neurotic Disorders | 1976 |
Effect of prolonged use of analgesics on pulpal response: a preliminary investigation.
Topics: Adult; Aged; Analgesics; Aspirin; Caffeine; Chlorpromazine; Dental Pulp; Dental Pulp Test; Dextropropoxyphene; Electric Stimulation; Female; Humans; Male; Middle Aged; Phenacetin; Time Factors; Toothbrushing | 1975 |
Influence of fibrinogen degradation products (FDP) on the central nervous system and on the effects of centrally acting drugs.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Depression, Chemical; Fibrin; Fibrinogen; Male; Rats; Stimulation, Chemical; Thiopental; Time Factors | 1975 |
[Acute toxicity and sedative action of zizyphus seeds (author's transl)].
Topics: Anesthesia, Intravenous; Animals; Caffeine; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Plant Extracts; Seeds | 1975 |
[Sympatholytic therapy of paralytic ileus].
Topics: Caffeine; Catecholamines; Chlorpromazine; Drug Therapy, Combination; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Parasympathomimetics; Propranolol; Sympatholytics; Trifluperidol | 1975 |
[The "structure of the motor behavior" of laboratory animals--new possibilities of the "open-field" method].
Topics: Amphetamine; Animals; Animals, Laboratory; Caffeine; Chlorpromazine; Female; Male; Motor Activity; Physiology; Rats; Research Design | 1992 |
Chlorpromazine-induced damage on nucleic acids: a combined cytogenetic and biochemical study.
Topics: Animals; Bacteriophage lambda; Caffeine; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chlorpromazine; DNA Damage; DNA, Viral; Doxorubicin; Drug Synergism; Escherichia coli; Humans; Intercalating Agents; Lymphocytes; Mice; Mice, Inbred BALB C; Mitotic Index; Plasmids; RNA; Sister Chromatid Exchange; Tumor Cells, Cultured | 1992 |
The course of a seasonal bipolar disorder influenced by caffeine.
Topics: Bipolar Disorder; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Haloperidol; Humans; Lithium; Middle Aged; Recurrence; Seasons | 1991 |
[Combined effects of pharmacological activation of the CNS and the complexity of mental tasks on the function of the cardiovascular and the vegetative nervous system and the work performance of operators].
Topics: Caffeine; Central Nervous System; Chlorpromazine; Efficiency; Humans; Occupational Medicine; Reaction Time; Work | 1990 |
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Neuroleptic Malignant Syndrome | 1989 |
Chemosensitization by chlorpromazine (CPZ) and caffeine (C) in human melanoma xenografts sensitive or resistant to methyl-CCNU (semustine).
Topics: Animals; Caffeine; Chlorpromazine; Drug Resistance; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Semustine; Stimulation, Chemical; Transplantation, Heterologous | 1989 |
Modulations by drugs of the relationship between calcium binding to troponin C and tension.
Topics: Animals; Caffeine; Calcium; Calmodulin; Chlorpromazine; In Vitro Techniques; Isometric Contraction; Melitten; Muscle Contraction; Myofibrils; Protein Binding; Quercetin; Sulfonamides; Trifluoperazine; Troponin; Troponin C | 1989 |
Chlorpromazine and trifluoperazine potentiate the action of adenosine on rat cerebral cortical neurons.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cerebral Cortex; Chlorpromazine; Depression, Chemical; Drug Synergism; Iontophoresis; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Synaptosomes; Trifluoperazine; Vasodilator Agents | 1985 |
Enhancement of cytogenetic damage by chlorpromazine in human lymphocytes treated with alkylating antineoplastics and caffeine.
Topics: Alkylating Agents; Caffeine; Cell Division; Cell Membrane; Chlorpromazine; Drug Synergism; Humans; In Vitro Techniques; Lymphocytes; Mitotic Index; Sister Chromatid Exchange | 1988 |
Psychomotor stimulant effects of caffeine alone and in combination with an adenosine analog in the squirrel monkey.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Food; Male; Motor Activity; Saimiri | 1987 |
Enhancement of semustine-induced cytotoxicity by chlorpromazine and caffeine in a human melanoma xenograft.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Caffeine; Chlorpromazine; DNA Damage; Drug Synergism; Humans; Male; Melanoma; Mice; Mice, Nude; Nitrosourea Compounds; Semustine; Tissue Distribution | 1986 |
The response of non-pregnant rat myometrium to oxytocin in Ca-free solution.
Topics: Animals; Caffeine; Calcium; Chlorpromazine; Female; Fluphenazine; In Vitro Techniques; Myometrium; Oxytocin; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Uterine Contraction | 1985 |
Rapid cooling contracture in frog striated muscles treated with chlorpromazine and haloperidol.
Topics: Animals; Caffeine; Chlorpromazine; Cold Temperature; Dantrolene; Haloperidol; Muscle Contraction; Muscles; Procaine; Ranidae; Time Factors; Toes | 1985 |
[Studies on the effect of various substances on platelet function with several methods].
Topics: Amphetamine; Anti-Anxiety Agents; Blood Platelets; Caffeine; Chlorpromazine; Debrisoquin; Dibenzazepines; Flurazepam; Guanethidine; Humans; Oxazoles; Papaverine; Phenytoin; Platelet Aggregation; Pyridines; Theophylline | 1973 |
[The effect of glaziovine on exploratory behavior of normal mice in the so-called "holey board" test].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Aporphines; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Exploratory Behavior; Female; Mice | 1974 |
Pharmacologically induced alterations of cortical and subcortical evoked potentials compared with physiological changes during the awake-sleep cycle in cats.
Topics: Amphetamine; Anesthetics; Animals; Atropine; Auditory Cortex; Caffeine; Cats; Central Nervous System Stimulants; Cerebral Cortex; Chloralose; Chlorpromazine; Computers; Dihydroxyphenylalanine; Electroencephalography; Evoked Potentials; Hippocampus; Imipramine; Lysergic Acid Diethylamide; Pentobarbital; Perphenazine; Physostigmine; Sleep; Thalamus; Tranquilizing Agents; Visual Cortex; Wakefulness | 1967 |
Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Bacillus anthracis; Caffeine; Chlorpromazine; Culture Media; Dinitrophenols; Enzyme Repression; Inosine Nucleotides; Lyases; Mutation; Phosphates; Theophylline | 1973 |
[Role of hypothalamic nonspecific structures in regulation of the pituitary-thyroid system].
Topics: Animals; Blood Proteins; Caffeine; Cats; Chlorpromazine; Electroencephalography; Hypothalamus; Iodine; Pituitary Gland; Protein Binding; Succinylcholine; Thyroid Gland; Thyroid Hormones; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine; Urethane | 1974 |
[Study of the uptake of Ca45 in various experimental conditions].
Topics: Abdominal Muscles; Animals; Brain; Caffeine; Calcium; Chlorpromazine; Muscles; Physical Exertion; Rats | 1971 |
Interaction of cations and local anesthetics with isolated sarcolemma.
Topics: Actomyosin; Adenosine Triphosphatases; Anesthetics, Local; Animals; Binding Sites; Caffeine; Calcium; Chlorpromazine; Enzyme Activation; Lipids; Magnesium; Mathematics; Procaine; Protein Binding; Protons; Quinine; Rabbits; Sarcolemma; Spectrophotometry, Atomic; Tetracaine; Zinc | 1972 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
The effect of PGE-1 on cyclic AMP and ion movements in turkey erythrocytes.
Topics: Animals; Biological Transport; Caffeine; Calcium; Calcium Chloride; Calcium Isotopes; Cattle; Chlorpromazine; Cyclic AMP; Depression, Chemical; Drug Synergism; Epinephrine; Erythrocytes; Guinea Pigs; Half-Life; Humans; Metabolism; Propranolol; Prostaglandins; Rabbits; Rats; Sodium; Sodium Isotopes; Stimulation, Chemical; Time Factors; Turkeys | 1971 |
On the pharmacology of cortical evoked potentials.
Topics: Acetamides; Animals; Caffeine; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Corpus Callosum; Dextroamphetamine; Electric Stimulation; Evoked Potentials; Phenobarbital; Pyrrolidinones; Reflex, Monosynaptic; Sciatic Nerve; Stereotaxic Techniques; Synaptic Transmission; Thiopental | 1972 |
Interaction of chloropromazine with adrenochrome and interference of a possible endogenous psychotogenic agent with some synaptic enzyme activities.
Topics: Adrenochrome; Animals; Ascorbic Acid; Brain; Caffeine; Chlorpromazine; Cholinesterase Inhibitors; Chromatography; Cyclic AMP; Drug Interactions; Hallucinogens; Haplorhini; Lithium; Monoamine Oxidase Inhibitors; Oxygen Consumption; Papio; Spectrophotometry; Synapses; Synaptosomes | 1972 |
Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.
Topics: 1-Propanol; Adenosine Diphosphate; Adenosine Monophosphate; Aminophylline; Blood Platelets; Caffeine; Chlorpromazine; Cyclic AMP; Desipramine; Dibenzothiepins; Epinephrine; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Piperazines; Platelet Adhesiveness | 1974 |
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine | 1974 |
Effects of central depressants and stimulants on EEG alterations induced by carotid cooling and warming.
Topics: Aminopyrine; Antidepressive Agents; Atropine; Caffeine; Carotid Arteries; Central Nervous System Stimulants; Chlorpromazine; Electroencephalography; Hot Temperature; Hypnotics and Sedatives; Hypothermia, Induced; Methamphetamine; Pentobarbital; Physostigmine; Reserpine | 1965 |
Flurothyl in mice: seizure, post-convulsive behavior, and interactions with psychotropic drugs.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Biperiden; Caffeine; Catalepsy; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Electroshock; Haloperidol; Humans; Imipramine; Iproniazid; Meprobamate; Monoamine Oxidase Inhibitors; Motor Activity; Parasympatholytics; Pargyline; Prenylamine; Procyclidine; Rats; Reflex; Reserpine; Seizures; Tranylcypromine | 1968 |
[Pharmacological studies on 2-methyl-4-amino-6-methoxy-s-triazine (CV399); with special reference to its central effects].
Topics: Amphetamine; Analgesics; Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Body Temperature; Brain Chemistry; Caffeine; Cats; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Drug Synergism; Ethanol; Haplorhini; Indoleacetic Acids; Male; Meprobamate; Methylphenidate; Mice; Morphine; Motor Activity; Pentobarbital; Piperidines; Rats; Reserpine; Respiration; Salivation; Seizures; Serotonin; Triazines | 1970 |
Effects of drugs acting alone and in combination on the motor activity of intact mice.
Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Diphenhydramine; Female; Glutamates; Hydroxybutyrates; Lactones; Meperidine; Meprobamate; Mice; Motor Activity; Nikethamide; Phenobarbital; Picrotoxin; Promethazine; Reflex; Scopolamine; Seizures; Strychnine; Tranquilizing Agents | 1970 |
[Introduction of mass psychology in animals to pharmacology. 6. Mutural relation in simultaneity convulsion and non-convulsin in E1-mice].
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Camphor; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imipramine; Mice; Nikethamide; Pentylenetetrazole; Rodent Diseases; Seizures; Tranquilizing Agents | 1970 |
Stimulant activity of pemoline and magnesium hydroxide.
Topics: Animals; Antacids; Ataxia; Caffeine; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Coma; Diazepam; Dogs; Drug Antagonism; Haplorhini; Hydroxides; Magnesium; Methamphetamine; Methylphenidate; Mice; Motor Activity; Pemoline; Pupil; Resins, Plant; Stimulation, Chemical; Tetrabenazine; Vomiting | 1969 |
Effect on pseudoconditioning of drugs with known central nervous activity.
Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione | 1974 |
Chlorpromazine-induced contracture of frog rectus abdominis muscle.
Topics: Acetylcholine; Adenosine; Animals; Arsenic; Atropine; Caffeine; Chlorpromazine; Choline; Cocaine; Cyanides; Electric Stimulation; Fluorides; Hexamethonium Compounds; In Vitro Techniques; Iodoacetates; Muscle Contraction; Ouabain; Physostigmine; Potassium Chloride; Procaine; Quinine; Sparteine; Stimulation, Chemical; Tubocurarine | 1974 |
Effects of chlorpromazine, imipramine, and quinidine on the mechanical activity of single skeletal muscle fibres of the frog.
Topics: Animals; Anura; Caffeine; Chlorpromazine; Drug Synergism; Electric Stimulation; Imipramine; Methods; Muscle Contraction; Myofibrils; Potassium; Quinidine; Rana temporaria; Tendons | 1972 |
The effects of drugs on calcium uptake and calcium release by mitochondria and sarcoplasmic reticulum of frog skeletal muscle.
Topics: Animals; Anura; Biological Transport; Brain; Caffeine; Calcium; Chlorpromazine; Imidazoles; In Vitro Techniques; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Muscles; Myocardium; Quinidine; Rana temporaria; Sarcoplasmic Reticulum; Time Factors | 1974 |
[Correlations and characteristics of the changes in electrical activity of the posterior hypothalamus and the motor cortex due to different pharmacological agents].
Topics: Animals; Caffeine; Carbachol; Chloral Hydrate; Chlorpromazine; Electroencephalography; Electrophysiology; Epinephrine; Hypothalamus; Motor Cortex; Rabbits; Scopolamine | 1973 |
The role of intracellular calcium in catecholamine secretion from the bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Caffeine; Calcium; Calcium Isotopes; Catecholamines; Cattle; Centrifugation, Density Gradient; Chlorpromazine; Chromaffin System; Colorimetry; Dextroamphetamine; Epinephrine; In Vitro Techniques; Magnesium; Mitochondria; Norepinephrine; Procaine; Subcellular Fractions; Sucrose | 1973 |
Rapid identification of acute drug intoxications.
Topics: Acute Disease; Caffeine; Chlorpromazine; Gastric Lavage; Glutethimide; Humans; Mass Spectrometry; Methods; Poisoning; Spectrum Analysis; Substance-Related Disorders; Time Factors | 1973 |
Brief communication: Enhancement of the antitumor effect of 1,-3-bis(2-chloroethyl)-1-nitrosourea by chlorpromazine and caffeine.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Leukemia L1210; Male; Mice | 1973 |
Interaction of Ca2+ and Mg2+ with synaptic plasma membranes.
Topics: Acetylcholine; Acetylcholinesterase; Anilino Naphthalenesulfonates; Animals; Caffeine; Calcium; Cations, Divalent; Centrifugation, Density Gradient; Chlorpromazine; Fluorometry; Magnesium; Procaine; Sheep; Succinate Dehydrogenase; Synaptic Membranes; Synaptosomes; Tetracaine | 1973 |
Differential changes in potency of platelet-aggregation inhibitors after preincubation in platelet-rich plasma.
Topics: Adenosine Diphosphate; Amitriptyline; Animals; Caffeine; Chlorpromazine; Diphenhydramine; Dipyridamole; Imipramine; Papaverine; Plasma; Platelet Adhesiveness; Swine; Time Factors; Trifluoperazine | 1974 |
[Experimental study on analysis of animal behavior and its quantification].
Topics: Animals; Behavior, Animal; Caffeine; Chlorpromazine; Computers; Male; Methamphetamine; Methods; Motor Activity; Rats; Reserpine | 1974 |
Effect of drugs on visually controlled avoidance behavior in rhesus monkeys: a psychophysical analysis.
Topics: Anesthetics; Animals; Avoidance Learning; Caffeine; Chlorpromazine; Dextroamphetamine; Escape Reaction; Hallucinogens; Haloperidol; Haplorhini; Lysergic Acid Diethylamide; Male; Morphine; Parasympatholytics; Pentobarbital; Phencyclidine; Piperidines; Psychopharmacology; Size Perception; Strychnine; Visual Perception | 1967 |
Self-administration of psychoactive substances by the monkey.
Topics: Animals; Behavior, Animal; Caffeine; Catheterization; Chlorpromazine; Cocaine; Codeine; Dextroamphetamine; Ethanol; Haplorhini; Humans; Mescaline; Morphinans; Morphine; Morphine Dependence; Pentobarbital; Substance-Related Disorders | 1969 |
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds | 1972 |
Effects of interaction with surfactants, adsorbents, and other substances on the permeation of chlorpromazine through a dimethyl polysiloxane membrane.
Topics: Bile Acids and Salts; Caffeine; Charcoal; Chlorpromazine; Diffusion; Drug Interactions; Gelatin; Glycolates; Hydrogen-Ion Concentration; Kinetics; Lactose; Membranes, Artificial; Mucins; Permeability; Riboflavin; Saccharin; Silicones; Surface-Active Agents; Tablets; Talc; Time Factors | 1971 |
A study of pharmaco-dynamics in periodic conditional processes in albino rats.
Topics: Animals; Avoidance Learning; Barbiturates; Caffeine; Chlorpromazine; Conditioning, Classical; Electroshock; Locomotion; Rats; Reaction Time | 1971 |
[Entropy dependent responses in two-dimensional conditional reflex controlled decision situations and their possible modelling].
Topics: Acoustic Stimulation; Animals; Caffeine; Chlorpromazine; Conditioning, Classical; Decision Making; Electric Stimulation; Learning; Male; Models, Psychological; Rats; Rats, Inbred Strains; Reaction Time | 1971 |
[The pain syndrome of the edentulous alveolar crest and its treatment].
Topics: Administration, Topical; Alveolar Process; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Caffeine; Chlorpromazine; Codeine; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Mouth, Edentulous; Pain; Phenobarbital; Procaine; Promethazine | 1969 |
Studies of the spontaneous movement of animals by the hole cross test; effect of 2-dimethyl-aminoethanol and its acyl esters on the central nervous system.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Deanol; Depression, Chemical; Esters; Ethanol; Ethylamines; Male; Methamphetamine; Methods; Mice; Motor Activity; Reserpine; Stimulation, Chemical | 1971 |
[Dependence of pharmacologic effects on the noise level].
Topics: Animals; Autonomic Agents; Barbiturates; Benactyzine; Caffeine; Central Nervous System; Chlorpromazine; Conditioning, Classical; Escape Reaction; Male; Noise; Rats; Reserpine; Sodium Chloride; Statistics as Topic | 1969 |
On the phenomenon of caffeine induced automutilation.
Topics: Animals; Caffeine; Central Nervous System; Chlorpromazine; Female; Humans; Male; Methamphetamine; Mice; Rats; Self Mutilation; Stimulation, Chemical | 1969 |
[Detection of sedative effect by electronystagmography].
Topics: Amphetamine; Antihypertensive Agents; Caffeine; Chlorpromazine; Dibenzazepines; Electric Stimulation; Humans; Hypnotics and Sedatives; Imidazoles; Methods; Pentobarbital; Phenmetrazine; Phenothiazines; Phenytoin; Promethazine; Thiethylperazine; Vestibular Function Tests | 1969 |
Calcium efflux from a heavy sarcotubular fraction. Effects of ryanodine, caffeine and magnesium.
Topics: Alkaloids; Animals; Biological Transport; Caffeine; Calcium; Chlorpromazine; Magnesium; Metabolism; Muscles; Oxalates; Quinidine; Rabbits; Uranium; Zinc | 1970 |
[The effect of several depriming substances on the evoked reflex pyramidal response].
Topics: Animals; Bemegride; Caffeine; Cats; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Hydroxybutyrates; Motor Neurons; Pyramidal Tracts; Reflex; Sensation; Skin; Sodium; Thiopental; Trifluoperazine | 1970 |
[Pharmacology of the active substances in betel. 3. Experiments with arecaidine].
Topics: Animals; Areca; Behavior, Animal; Bile; Blood Glucose; Blood Pressure; Caffeine; Chlorpromazine; Depression, Chemical; Diuresis; Dogs; Drug Synergism; Efficiency; Glutamates; Hexobarbital; Imipramine; Learning; Mice; Nicotinic Acids; Parasympathomimetics; Perception; Phenothiazines; Plant Extracts; Plants, Medicinal; Psychopharmacology; Rats; Reserpine; Stimulation, Chemical | 1970 |
[A comparative study of the neuronal reactions of the paleo- and neo-cortex of the guinea pig brain].
Topics: Animals; Caffeine; Cerebral Cortex; Chlorpromazine; Electrophysiology; Guinea Pigs; Hearing; Hippocampus; Neurons; Pain; Sensation; Smell; Somatosensory Cortex | 1970 |
[Action of some stimulants and depressants on simple extinction].
Topics: Amphetamine; Animals; Caffeine; Chlorpromazine; Conditioning, Classical; Extinction, Psychological; Meprobamate; Morphine; Motivation; Pentobarbital; Psychopharmacology; Rats | 1970 |
[Intraspecific aggressive behavior induced by apomorphine in the rat].
Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine | 1970 |
Neuropharmacological properties of Su17595A a chlorpromazine-like central nervous system depressant.
Topics: Animals; Blood Pressure; Brain Stem; Caffeine; Cats; Chlordiazepoxide; Chlorpromazine; Cocaine; Depression, Chemical; Dextroamphetamine; Drug Antagonism; Hypnotics and Sedatives; Male; Mice; Morphine; Morpholines; Motor Activity; Pentylenetetrazole; Piperazines; Propiophenones; Rats; Reflex; Respiration; Seizures; Strychnine; Tranquilizing Agents | 1971 |
[Detection of drugs in knee joint synovia].
Topics: Albumins; Aspirin; Binding Sites; Biological Transport; Caffeine; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Diazepam; Ephedrine; Forensic Medicine; Humans; Knee Joint; Meprobamate; Methods; Molecular Weight; Morphine; Phenacetin; Phenylbutazone; Procaine; Synovial Fluid; Synovial Membrane | 1971 |
Identification and metabolism of some doping substances in horses.
Topics: Amphetamine; Animals; Caffeine; Chlorpromazine; Chromatography; Gentisates; Horses; Methods; Pharmaceutical Preparations; Phenylbutazone; Salicylates; Spectrophotometry; Sports; Time Factors; Veterinary Medicine | 1967 |
[Behavioral dissociation at the level of the relation of ingestion and the number of merycism cycles in sheep].
Topics: Abomasum; Amphetamine; Animals; Antineoplastic Agents; Caffeine; Chlorpromazine; Circadian Rhythm; Depression, Chemical; Digitalis Glycosides; Ephedrine; Feeding Behavior; Imipramine; Iproniazid; Lanatosides; Mescaline; Pentobarbital; Reserpine; Sheep; Stimulation, Chemical; Stomach, Ruminant | 1967 |
[On the pharmacology of the active substances of betel. 1. Central effect of arecoline].
Topics: Amphetamine; Analgesics; Animals; Areca; Atropine; Barbiturates; Caffeine; Central Nervous System; Chlorpromazine; Cocaine; Conditioning, Classical; Depression, Chemical; Exploratory Behavior; Mice; Movement; Mydriatics; Nicotinic Acids; Pentylenetetrazole; Phenothiazines; Plants, Medicinal; Reserpine | 1967 |
[The influence of centrally acting drugs on directional hearing of normal subjects in a free acoustic field].
Topics: Aged; Audiometry; Auditory Perception; Benactyzine; Caffeine; Chlorpromazine; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Strychnine | 1968 |
[Kulenkampf-Tarnow syndrome, problems of its pathogenesis and treatment].
Topics: Adolescent; Adult; Atropine; Brain Stem; Caffeine; Chlorpromazine; Ephedrine; Humans; Male; Masticatory Muscles; Mesencephalon; Muscle Cramp; Reticular Formation; Schizophrenia; Seizures; Trismus | 1968 |
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental | 1968 |
[On the dependence of pharmacologic effects on the ambient brightness].
Topics: Animals; Barbiturates; Benactyzine; Caffeine; Central Nervous System; Chlorpromazine; Conditioning, Classical; Environmental Exposure; Escape Reaction; Injections, Subcutaneous; Light; Male; Rats; Reserpine | 1968 |
The action of stimulant and depressant agents on local cerebral impedance and circulation.
Topics: Amphetamine; Animals; Blood Flow Velocity; Blood Pressure; Caffeine; Cats; Cerebral Cortex; Cerebrovascular Circulation; Chlorpromazine; Electrocardiography; Electroencephalography; Ethyl Ethers; Heart; Hippocampus; Hypothalamus; Pentobarbital; Reticular Formation; Thalamus | 1964 |
[Pharmacological effects on running performance of rats in different performance reward and different performance conditions].
Topics: Amphetamine; Animals; Barbiturates; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Imipramine; Meprobamate; Physical Exertion; Rats; Reward | 1965 |
[The influence of centrally active drugs on sound perception in normally hearing subjects using a binaural speech test].
Topics: Benactyzine; Caffeine; Chlorpromazine; Hearing; Hearing Tests; Humans; Meprobamate; Phenobarbital; Psychopharmacology; Strychnine | 1965 |
Experimental observations on the pharmacology of the pontine respiration center.
Topics: Animals; Caffeine; Cats; Chlorpromazine; Morphine; Pentobarbital; Pentylenetetrazole; Piperidines; Respiration; Reticular Formation; Urethane | 1967 |
Inhibition of evoked potentials by caudate stimulation and its antagonism by centrally acting drugs.
Topics: Amphetamine; Amygdala; Animals; Bemegride; Caffeine; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrophysiology; Evoked Potentials; Forelimb; Hippocampus; Hypothalamus; Imipramine; Medulla Oblongata; Mephenesin; Morphine; Neurons; Pentobarbital; Pentylenetetrazole; Picrotoxin; Reticular Formation; Strychnine; Thalamus | 1967 |
Central nervous system activity of 1-(3-methoxypropylamino)-2-hydroxy-2-(1,4-benzodioxan-2-yl)-ethane hydrochloride.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Desipramine; Drug Synergism; Electroencephalography; Humans; Methamphetamine; Phenelzine; Rats; Reserpine; Reticular Formation; Sympatholytics; Thiopental | 1967 |
Tolerance to N6-(L-phenylisopropyl) adenosine. Contribution of behavioral mechanisms and cross-tolerance profile.
Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic | 1984 |
Influences on drugs on evoked potentials in the cat cerebellum: I. Effects of CNS depressants and stimulants on the cerebellar afferent pathways.
Topics: Animals; Caffeine; Cats; Central Nervous System Depressants; Central Nervous System Stimulants; Cerebellum; Chlorpromazine; Evoked Potentials; Female; Male; Meprobamate; Neural Pathways; Pentobarbital; Picrotoxin; Strychnine | 1982 |
Action of antidepressants, stimulants and depressants in the transition from a fixed ratio to a fixed interval schedule of reinforcement.
Topics: Amitriptyline; Amphetamine; Animals; Caffeine; Chlorpromazine; Conditioning, Operant; Diazepam; Doxepin; Imipramine; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Reinforcement Schedule | 1983 |
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri | 1983 |
The locus coeruleus: actions of psychoactive drugs.
Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine | 1983 |
[Malignant hyperthermia-results of familial investigations in Austria (author's transl)].
Topics: Adenosine Triphosphate; Austria; Caffeine; Calcium; Chlorpromazine; Creatine Kinase; Halothane; Humans; In Vitro Techniques; Isoenzymes; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride | 1981 |
Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.
Topics: Caffeine; Central Nervous System; Chlorpromazine; Diazepam; Humans; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Sperm Motility | 1982 |
Effects of psychotropic drugs on impairment of acquisition of shuttle avoidance produced by pretreatment with pairs of tone signal and shock in mice.
Topics: Animals; Avoidance Learning; Caffeine; Chlorpromazine; Diazepam; Electroshock; Imipramine; Male; Mice; Morphine; Nicotine; Psychotropic Drugs; Signal Detection, Psychological | 1994 |
Some effects of drugs on visual discrimination in the pigeon.
Topics: Animals; Caffeine; Chlorpromazine; Columbidae; Humans; Learning; Lysergic Acid Diethylamide; Meperidine; Pentobarbital; Visual Perception | 1957 |
Effects of caffeine and chlorpromazine on the sexual behavior of male rats.
Topics: Animals; Caffeine; Chlorpromazine; Male; Rats; Sexual Behavior | 1958 |
[Pharmacological studies on the central nervous system by means of experimental perfusion of the cerebral ventricles and subarachnoid space. III. With special reference to the excretion of irrigation fluids and changes in the blood pressure during the use
Topics: Acetylcholine; Blood Pressure; Brain; Caffeine; Cerebral Ventricles; Chlorpromazine; Curare; Epinephrine; Histamine; Humans; Perfusion; Subarachnoid Space | 1962 |
Central cholinolytic action of chlorpromazine.
Topics: Acetylcholine; Animals; Brain; Caffeine; Chlorpromazine; Cholinergic Antagonists; Electroencephalography; Parasympatholytics; Physostigmine; Rabbits | 1962 |
[Changes in auditory adaptation caused by drugs acting on the central nervous system].
Topics: Acclimatization; Bromine; Caffeine; Central Nervous System; Chlorpromazine; Hearing; Hearing Tests; Humans | 1963 |
[Vasomotor reactions of the vascular network of the rabbit ear during acute fatigue under the influence of certain neurovasotropic substances].
Topics: Acetylcholine; Animals; Blood Vessels; Caffeine; Chlorpromazine; Epinephrine; Fatigue; Rabbits; Serotonin; Vasomotor System | 1963 |
Course of some pharmacological tests in functionally decorticated animals.
Topics: Amphetamine; Amphetamines; Animals; Caffeine; Cerebral Cortex; Cerebral Decortication; Chlorpromazine; Ethers; Magnesium Sulfate; Meperidine; Morphine; Pentylenetetrazole; Phenylbutazone; Pregnanediones; Strychnine; Thiopental | 1963 |
[The influence of drugs with central active components on oxygen consumption in carp].
Topics: Animals; Barbiturates; Caffeine; Carps; Central Nervous System; Chlorpromazine; Energy Metabolism; Ethanol; Metabolism; Oxygen Consumption; Strychnine; Urethane | 1963 |
Drugs that modify actions of pharmacologically active polypeptides.
Topics: Atropine; Bradykinin; Caffeine; Chlorpromazine; Dibucaine; Ergot Alkaloids; Humans; Hypertension; Lysergic Acid Diethylamide; Morphine; Oxytocin; Peptides; Phenoxybenzamine; Reserpine; Tripelennamine; Vasopressins; Vitamin B 12 | 1963 |
[ON THE MECHANISM OF INHIBITION OF INFLAMMATORY EDEMA WITH CAFFEINE, WITH REFERENCE TO SEROTONIN].
Topics: Caffeine; Chlorpromazine; Dextrans; Edema; Epinephrine; Formaldehyde; Inflammation; Rats; Research; Selective Serotonin Reuptake Inhibitors; Serotonin | 1963 |
RELATIONSHIP BETWEEN CHOLINERGIC DRUGS AND EEG ACTIVATION.
Topics: Atropine; Bemegride; Caffeine; Chlordiazepoxide; Chlorpromazine; Cholinergic Agents; Dextroamphetamine; Electroencephalography; Lysergic Acid Diethylamide; Methylphenidate; Morphine; Parasympathomimetics; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenoxybenzamine; Physostigmine; Rabbits; Research | 1963 |
THE CENTRAL EFFECTS OF XYLOPININE IN MICE.
Topics: Amobarbital; Berberine Alkaloids; Caffeine; Central Nervous System; Chlorpromazine; Hypnotics and Sedatives; Methamphetamine; Mice; Nervous System; Pharmacology; Quinolizines; Research; Tetrabenazine; Toxicology; Tranquilizing Agents | 1963 |
[DYNAMICS OF SUBORDINATION AND ADAPTATION IN PATIENTS WITH THE CATATONIC FORM OF SCHIZOPHRENIA WITH CHRONIC UNFAVORABLE DEVELOPMENT].
Topics: Acclimatization; Adaptation, Physiological; Caffeine; Catatonia; Central Nervous System; Chlorpromazine; Epinephrine; Humans; Schizophrenia; Schizophrenic Psychology | 1963 |
ASSAY PROCEDURE FOR PHARMACEUTICAL COMBINATIONS OF ASPIRIN, PHENACETIN, CAFFEINE, AND ITOBARBITAL WITH PHENOTHIAZINE DERIVATIVES. I.
Topics: Anti-Bacterial Agents; Antipsychotic Agents; Aspirin; Barbiturates; Caffeine; Chemistry, Pharmaceutical; Chlorpromazine; Phenacetin; Phenothiazines; Promethazine; Research; Thiethylperazine; Thioridazine | 1964 |
[ON A NEW METHOD OF RECORDING MOVEMENT IN THE LABORATORY ANIMAL MAINTAINED IN ITS REARING ENVIRONMENT--ITS APPLICATION TO THE STUDY OF SOME BEHAVIOR-MODIFYING AGENTS].
Topics: Amphetamine; Amphetamines; Animals; Animals, Laboratory; Barbiturates; Behavior, Animal; Caffeine; Chlorpromazine; Cinnamates; Cyanides; Heterocyclic Compounds; Hypnotics and Sedatives; Injections, Intraperitoneal; Mice; Morphine; Movement; Pharmacology; Phenobarbital; Research; Reserpine | 1964 |
[EXPERIMENTAL STUDIES ON THE EFFECT OF SOME PHARMACOLOGICAL PREPARATIONS ON THE ANESTHETIC ACTIVITY OF COCAINE].
Topics: Adjuvants, Anesthesia; Anesthetics; Anura; Caffeine; Chlorpromazine; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Humans; Nitrates; Pentylenetetrazole; Pharmacology; Phenobarbital; Rabbits; Research; Reserpine | 1964 |
PLASMA FREE FATTY ACIDS IN RATS AFTER SHOCK AS MODIFIED BY CENTRALLY ACTIVE DRUGS.
Topics: Amphetamine; Amphetamines; Blood; Caffeine; Chlordiazepoxide; Chlorpromazine; Electroshock; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Hydroxyzine; Meprobamate; Pentobarbital; Pharmacology; Rats; Research; Reserpine; Stress, Physiological; Tranquilizing Agents | 1964 |
EFFECTS OF CENTRALLY ACTING DRUGS ON CONFINEMENT MOTOR ACTIVITY.
Topics: Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Methylphenidate; Motor Activity; Movement; Pharmacology; Phenmetrazine; Piperidines; Prochlorperazine; Rats; Research; Tranylcypromine; Trifluoperazine | 1964 |
COMPARISON OF DRUG EFFECTS ON APPROACH, AVOIDANCE, AND ESCAPE MOTIVATION.
Topics: Amobarbital; Avoidance Learning; Caffeine; Chlordiazepoxide; Chlorpromazine; Ethanol; Methamphetamine; Motivation; Psychopharmacology; Rats; Research; Reward | 1965 |
TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS.
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Biomedical Research; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Deanol; Drug Therapy; Electroencephalography; Lysergic Acid Diethylamide; Meprobamate; Orphenadrine; Pentobarbital; Perphenazine; Pharmacology; Phenobarbital; Placebos; Schizophrenia; Statistics as Topic; Tranquilizing Agents | 1965 |
DRUG-INDUCED DISSOCIATION BETWEEN EVOKED RETICULAR POTENTIALS AND THE EEG.
Topics: Amphetamine; Amphetamines; Animals; Antidepressive Agents; Atropine; Brain; Caffeine; Catechols; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electrophysiology; Hallucinogens; Humans; Imipramine; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pentylenetetrazole; Phenoxybenzamine; Rabbits; Research; Reticular Formation; Scopolamine; Thioridazine; Tranquilizing Agents | 1965 |
[Comparative results in the treatment of early pregnancy toxemias with bromine, caffeine and aminazin].
Topics: Bromides; Bromine; Caffeine; Chlorpromazine; Female; Pre-Eclampsia; Pregnancy; Toxemia | 1962 |
[Influence of the gastrointestinal motility by injection of various pharmaceutical agents into the cisternal space].
Topics: Caffeine; Chlorpromazine; Cisterna Magna; Gastrointestinal Motility; Humans; Injections; Thiopental | 1962 |
Antineoplastic and cytogenetic effects of chlorpromazine on human lymphocytes in vitro and on Ehrlich ascites tumor cells in vivo.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Proliferation; Cells, Cultured; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Humans; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mitomycin; Sister Chromatid Exchange; Survival Analysis | 2009 |
A fatal case of potential chronic overdoses of prescribed and proprietary remedies.
Topics: Adult; Analgesics; Caffeine; Chlorpromazine; Clomipramine; Drug Overdose; Fatal Outcome; Heart Arrest; Humans; Liver; Lung; Male; Pulmonary Edema; Substance Abuse Detection | 2010 |
Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models.
Topics: Animals; Anticonvulsants; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Convulsants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reaction Time; Seizures; Theophylline; Time Factors; Tramadol | 2012 |
Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro?
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Calcium; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chlorpromazine; Diclofenac; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Omeprazole; Primary Cell Culture; Sex Characteristics; Verapamil | 2015 |
The assessment of mouse spontaneous locomotor activity using motion picture.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Hypnotics and Sedatives; Locomotion; Male; Mice, Inbred C57BL; Motion Pictures; Motor Activity | 2020 |