chlorpromazine and bupivacaine

chlorpromazine has been researched along with bupivacaine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's5 (22.73)18.2507
2000's3 (13.64)29.6817
2010's7 (31.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Englesson, S; Göller, H; Larsson, B; Lyttkens, L; Stahle, J1
Englesson, S; Larsson, B; Lyttkens, L; Stahle, J1
Kimura, I; Kimura, M; Muroi, M; Nojima, H1
Kimura, I; Kimura, M; Kondoh, T; Tsuneki, H2
DiPaola, M; Kao, PN; Karlin, A1
Wood, M1
Hou, SM1
Belfrage, P; Raabe, N; Thalme, B2
Kuusi, T; Mäkelä, A; Schröder, T1
Cassu, RN; Castro, GB; Lopes, MD; Luna, SP; Silva Júnior, JR; Teixeira Neto, FJ1
Chen, YC; Chen, YW; Chu, CC; Kan, CD; Wang, JJ1

Reviews

1 review(s) available for chlorpromazine and bupivacaine

ArticleYear
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986

Other Studies

21 other study(ies) available for chlorpromazine and bupivacaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Melanin capacity to accumulate drugs in the internal ear. A study on lidocaine, bupivacaine and chlorpromazine.
    Acta oto-laryngologica, 1979, Volume: 88, Issue:1-2

    Topics: Animals; Autoradiography; Bupivacaine; Chlorpromazine; Ear, Inner; Eye; Hearing; Humans; Injections, Intraperitoneal; Injections, Intravenous; Lidocaine; Melanins; Rats; Time Factors; Vision, Ocular

1979
Accumulation of substances with melanin affinity to the internal ear. Therapeutic or ototoxic mechanism?
    Advances in oto-rhino-laryngology, 1979, Volume: 25

    Topics: Animals; Autoradiography; Bupivacaine; Chlorpromazine; Ear, Inner; Injections, Intraperitoneal; Injections, Intravenous; Lidocaine; Melanins; Rats

1979
Mechanism of the blocking action of beta-eudesmol on the nicotinic acetylcholine receptor channel in mouse skeletal muscles.
    Neuropharmacology, 1991, Volume: 30, Issue:8

    Topics: Animals; Bupivacaine; Chlorpromazine; Drugs, Chinese Herbal; Male; Membrane Potentials; Mice; Motor Endplate; Muscles; Phencyclidine; Receptors, Nicotinic; Sesquiterpenes, Eudesmane; Terpenes

1991
Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Aequorin; Animals; Anti-Ulcer Agents; Bupivacaine; Calcium; Calcium Channel Blockers; Chlorpromazine; Cholinergic Antagonists; Diaphragm; Male; Mice; Muscle Contraction; Muscle, Smooth; Neostigmine; Nicotinic Antagonists; Peptides, Cyclic; Phencyclidine; Receptors, Cholinergic; Receptors, Nicotinic; Sesquiterpenes, Eudesmane; Sodium; Terpenes

1991
Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Aequorin; Animals; Bupivacaine; Calcium; Chlorpromazine; Diaphragm; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Pancuronium; Phencyclidine; Sesquiterpenes, Eudesmane; Succinylcholine; Terpenes; Time Factors

1991
Mapping the alpha-subunit site photolabeled by the noncompetitive inhibitor [3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Acetylcholine; Affinity Labels; Amino Acid Sequence; Amphibian Venoms; Animals; Azides; Binding Sites; Bupivacaine; Chlorpromazine; Chromatography, High Pressure Liquid; Cyanogen Bromide; Molecular Sequence Data; Molecular Weight; Nicotinic Antagonists; Peptide Fragments; Peptide Mapping; Photochemistry; Proadifen; Quinacrine; Receptors, Nicotinic; Torpedo

1990
[Effect of spasmolytic agents on microanastomosis of femoral artery of rats].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1988, Volume: 87, Issue:4

    Topics: Anastomosis, Surgical; Animals; Bupivacaine; Chlorpromazine; Femoral Artery; Lidocaine; Microsurgery; Parasympatholytics; Rats; Rats, Inbred Strains

1988
Lumbar epidural analgesia in labour. I. Acid-base balance and clinical condition of mother, fetus and newborn child.
    Acta obstetricia et gynecologica Scandinavica, 1974, Volume: 53, Issue:1

    Topics: Acidosis; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood; Body Temperature; Bradycardia; Bupivacaine; Carbon Dioxide; Chlorpromazine; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Labor, Obstetric; Meperidine; Nerve Block; Nitrous Oxide; Obstetric Labor Complications; Pregnancy; Pressure; Prilocaine; Pulse; Respiration; Time Factors

1974
Lumbar epidural analgesia in labour. II. Effects on glucose, lactate, sodium, chloride, total protein, haematocrit and haemoglobin in maternal, fetal and neonatal blood.
    Acta obstetricia et gynecologica Scandinavica, 1974, Volume: 53, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Glucose; Blood Proteins; Bupivacaine; Chlorides; Chlorpromazine; Female; Fetus; Hematocrit; Hemoglobins; Humans; Infant, Newborn; Labor, Obstetric; Lactates; Meperidine; Nitrous Oxide; Pregnancy; Prilocaine; Sodium

1974
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
    Scandinavian journal of clinical and laboratory investigation, 1997, Volume: 57, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Chlorpromazine; Digoxin; Enzyme Inhibitors; Glucocorticoids; Humans; Lidocaine; Pancreatitis; Phospholipases A; Phospholipases A2

1997
Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section.
    The Veterinary record, 2004, Mar-27, Volume: 154, Issue:13

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Bupivacaine; Cesarean Section; Chlorpromazine; Dogs; Enflurane; Epinephrine; Female; Heart Rate; Ketamine; Lidocaine; Midazolam; Pregnancy; Propofol; Random Allocation; Reflex; Respiration; Thiopental

2004
Promazine and chlorpromazine for prolonged spinal anesthesia in rats.
    Neuroscience letters, 2012, Jul-19, Volume: 521, Issue:2

    Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Bupivacaine; Chlorpromazine; Dose-Response Relationship, Drug; Injections, Spinal; Male; Motor Activity; Nociception; Promazine; Rats; Rats, Sprague-Dawley; Reflex; Spinal Puncture; Vocalization, Animal

2012