chlorpromazine and benztropine

chlorpromazine has been researched along with benztropine in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (80.43)	18.7374
1990's	2 (4.35)	18.2507
2000's	2 (4.35)	29.6817
2010's	4 (8.70)	24.3611
2020's	1 (2.17)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL	1
Kay, SR; Singh, MM	3
Canter, JW; Giordano, J; Huang, A	1
Evans, DL; Peiper, SC; Rogers, JF	1
Tuomisto, J; Tuomisto, L	1
Crow, TJ; Deakin, JF; Longden, A	1
Forester, D	1
Bokan, J; McGuire, J; Scher, M; Storrie, MC	1
Cole, JO; Shapiro, S; Slone, D; Swett, C	1
Edelstein, BA; Hersen, M; Pinkston, SG; Turner, SM	1
Sachdev, P; Tang, WM	1
Casey, DE; Keepers, GA	1
Kerr, S; Marshall, G; O'Gorman-Hughes, D; Vowels, M; White, L	1
Bowers, MB; Swigar, ME	1
Darko, D; Gillin, JC; Glassman, JN	1
Kruk, ZL; Millar, J; Stamford, JA	2
Kay, SR; Opler, LA; Singh, MM	1
Corsaro, CJ; Kellams, JJ; Miller, MJ; Milstein, V; Small, IF; Small, JG	1
Carman, JS; Tucker, LS	1
Bowers, MB; Roth, RH	1
Nose, T; Segawa, T	1
Poirier, LJ	1
Asnes, DP	1
Andersen, PR; Gibbs, P; Kubinski, H	1
Abuzzahab, FS; Kelly, JT; Schiele, BC; Zimmermann, RL	1
Carmichael, FJ; Israel, Y	1
Larson, CP; Sarnquist, F	1
Oppenheim, G	1
Ray, I	1
Morrison, AB; Webster, RA	1
Lahti, RA; Losey, EG	1
Lee, T; Seeman, P	1
Villeneuve, A	1
Glezos, JD; Stadnyk, AN	1
Spaan, SJ; Westerink, BH	1
Falterman, CG; Richardson, CJ	1

Reviews

3 review(s) available for chlorpromazine and benztropine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective. Medicinal research reviews, 2021, Volume: 41, Issue:1 Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization	2021
Nervous mechanisms involved in experimentally induced extrapyramidal disturbances. Confinia neurologica, 1974, Volume: 36, Issue:4-6 Topics: Animals; Basal Ganglia Diseases; Benztropine; Brain; Cats; Caudate Nucleus; Cerebellar Nuclei; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dopamine; Haloperidol; Haplorhini; Humans; Levodopa; Movement Disorders; Olivary Nucleus; Parkinson Disease; Putamen; Rats; Red Nucleus; Substantia Nigra; Thalamic Nuclei; Tremor	1974

Trials

5 trial(s) available for chlorpromazine and benztropine

Article	Year
Therapeutic reversal with benxtropine in schizophrenics. Practical and theoretical significance. The Journal of nervous and mental disease, 1975, Volume: 160, Issue:4 Topics: Adult; Affect; Attention; Benztropine; Chlorpromazine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Hallucinations; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; Social Behavior; Thinking; Tropanes	1975
A comparative study of haloperidol and chlorpromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia. Theoretical implications for potency differences among neuroleptics. Psychopharmacologia, 1975, Aug-21, Volume: 43, Issue:2 Topics: Adult; Affect; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Haloperidol; Heart Rate; Humans; Male; Mental Processes; Middle Aged; Parasympatholytics; Schizophrenia; Sleep; Social Behavior; Time Factors; Tropanes	1975
Antiemetic therapy for chemotherapy-induced vomiting: metoclopramide, benztropine, dexamethasone, and lorazepam regimen compared with chlorpromazine alone. The Journal of pediatrics, 1989, Volume: 115, Issue:1 Topics: Adolescent; Antineoplastic Agents; Benztropine; Child; Child, Preschool; Chlorpromazine; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lorazepam; Male; Metoclopramide; Random Allocation; Sleep Stages; Tropanes; Vomiting	1989
Computerized EEG profiles of haloperidol, chlorpromazine, clozapine and placebo in treatment resistant schizophrenia. Clinical EEG (electroencephalography), 1987, Volume: 18, Issue:3 Topics: Adolescent; Adult; Alpha Rhythm; Benztropine; Beta Rhythm; Brain Mapping; Chlorpromazine; Clozapine; Delta Rhythm; Dibenzazepines; Double-Blind Method; Electroencephalography; Female; Haloperidol; Humans; Male; Schizophrenia; Signal Processing, Computer-Assisted; Theta Rhythm	1987
A double-blind study of amantadine hydrochloride versus benztropine mesylate in drug-induced parkinsonism. Pharmacology, 1974, Volume: 12, Issue:2 Topics: Administration, Oral; Amantadine; Antiparkinson Agents; Benztropine; Capsules; Chlorpromazine; Clinical Trials as Topic; Humans; Parkinson Disease; Parkinson Disease, Secondary; Placebos; Schizophrenia; Time Factors	1974

Other Studies

38 other study(ies) available for chlorpromazine and benztropine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Therapeutic antagonism between anticholinergic antiparkinsonism agents and neuroleptics in schizophrenia. Implications for a neuropharmacological model. Neuropsychobiology, 1979, Volume: 5, Issue:2 Topics: Antiparkinson Agents; Antipsychotic Agents; Benztropine; Chlorpromazine; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Schizophrenia; Trihexyphenidyl	1979
Fatal paralytic ileus complicating phenothiazine therapy. Southern medical journal, 1975, Volume: 68, Issue:3 Topics: Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Colon; Female; Humans; Intestinal Mucosa; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Peritonitis; Schizophrenia; Trifluoperazine	1975
Intestinal dilatation associated with phenothiazine therapy: a case report and literature review. The American journal of psychiatry, 1979, Volume: 136, Issue:7 Topics: Adult; Benztropine; Bipolar Disorder; Chlorpromazine; Dilatation, Pathologic; Drug Therapy, Combination; Gastrointestinal Motility; Humans; Intestinal Diseases; Intestines; Lithium; Male	1979
The accumulation of dopamine into striatal synaptosomes, and its inhibition: comparison of crude, partially purified and purified synaptosomal preparations. Medical biology, 1979, Volume: 57, Issue:4 Topics: Amphetamine; Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Imipramine; Kinetics; Nomifensine; Rats; Receptors, Dopamine; Reserpine; Subcellular Fractions; Synaptosomes	1979
The nucleus accumbens--possible site of antipsychotic action of neuroleptic drugs? Psychological medicine, 1977, Volume: 7, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Fluphenazine; Homovanillic Acid; Humans; Male; Psychotic Disorders; Rats; Receptors, Dopamine; Scopolamine; Tegmentum Mesencephali; Thioridazine; Tranquilizing Agents	1977
Fatal drug-induced heat stroke. JACEP, 1978, Volume: 7, Issue:6 Topics: Adult; Benztropine; Chlorpromazine; Drug Therapy, Combination; Heat Exhaustion; Humans; Male; Schizophrenia, Paranoid; Tropanes	1978
Thrombocytopenia in the absence of leukopenia associated with the use of neuroleptics. The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10 Topics: Adult; Benztropine; Chlorpromazine; Haloperidol; Humans; Male; Perphenazine; Schizophrenia; Thalassemia; Thrombocytopenia; Trifluoperazine; Trihexyphenidyl; Tropanes	1978
Extrapyramidal side effects in chlorpromazine recipients: emergence according to benztropine prophylaxis. Archives of general psychiatry, 1977, Volume: 34, Issue:8 Topics: Adult; Affective Disorders, Psychotic; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Drug Therapy, Combination; Female; Humans; Male; Personality Disorders; Schizophrenia; Tropanes	1977
Effects of phenothiazines and social skills training in a withdrawn schizophrenic. Journal of clinical psychology, 1975, Volume: 31, Issue:4 Topics: Adult; Behavior Therapy; Benztropine; Chlorpromazine; Feedback; Follow-Up Studies; Generalization, Psychological; Humans; Hygiene; Imitative Behavior; Male; Occupational Therapy; Perphenazine; Schizophrenia; Set, Psychology; Social Behavior; Token Economy; Trifluoperazine; Tropanes; Verbal Behavior	1975
Psychotic symptoms preceding ocular deviation in a patient with tardive oculogyric crises. The Australian and New Zealand journal of psychiatry, 1992, Volume: 26, Issue:4 Topics: Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Fluphenazine; Haloperidol; Humans; Infusions, Intravenous; Male; Neurologic Examination; Ocular Motility Disorders; Psychoses, Substance-Induced; Schizophrenia; Schizophrenic Psychology	1992
Use of neuroleptic-induced extrapyramidal symptoms to predict future vulnerability to side effects. The American journal of psychiatry, 1991, Volume: 148, Issue:1 Topics: Adult; Age Factors; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Disease Susceptibility; Female; Humans; Male; Medical Records; Parkinson Disease, Secondary; Probability; Recurrence; Risk Factors; Sex Factors	1991
Psychotic patients who become worse on neuroleptics. Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Psychoses, Substance-Induced; Psychotic Disorders; Thiothixene	1988
Medication-induced somnambulism in a patient with schizoaffective disorder. The Journal of clinical psychiatry, 1986, Volume: 47, Issue:10 Topics: Adult; Benztropine; Chlorpromazine; Humans; Lithium; Lithium Carbonate; Male; Psychotic Disorders; Psychotropic Drugs; Somnambulism; Triazolam	1986
Sub-second striatal dopamine release measured by in vivo voltammetry. Brain research, 1986, Sep-03, Volume: 381, Issue:2 Topics: Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Electrochemistry; Male; Medial Forebrain Bundle; Metoclopramide; Pargyline; Pergolide; Rats; Rats, Inbred Strains	1986
Anticholinergic-neuroleptic antagonism in terms of positive and negative symptoms of schizophrenia: implications for psychobiological subtyping. Psychological medicine, 1987, Volume: 17, Issue:1 Topics: Adolescent; Adult; Benztropine; Chlorpromazine; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychopathology; Schizophrenia; Schizophrenic Psychology; Trihexyphenidyl; Tropanes	1987
Measurement of stimulated dopamine release in the rat by in vivo voltammetry: the influence of stimulus duration on drug responses. Neuroscience letters, 1986, Aug-15, Volume: 69, Issue:1 Topics: Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Electric Stimulation; Electrochemistry; Male; Metoclopramide; Rats; Rats, Inbred Strains; Time Factors	1986
Letter: Benztropine in childhood hyperkinesis. Lancet (London, England), 1973, Dec-08, Volume: 2, Issue:7841 Topics: Adolescent; Benztropine; Child; Chlorpromazine; Humans; Hyperkinesis; Male; Methylphenidate; Tropanes	1973
Interaction of atropine-like drugs with dopamine-containing neurones in rat brain. British journal of pharmacology, 1972, Volume: 44, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Neurons; Orphenadrine; Phenothiazines; Procyclidine; Rats; Time Factors; Trihexyphenidyl	1972
A comparison of the inhibitory effects of certain antiparkinsonian agents on dopamine accumulation into the rat striatum. Japanese journal of pharmacology, 1974, Volume: 24, Issue:2 Topics: Animals; Antidepressive Agents; Antiparkinson Agents; Atropine; Benztropine; Chlorpromazine; Corpus Striatum; Diphenhydramine; Dopamine; Glycolates; Male; Mitochondria; Ouabain; Phenothiazines; Rats; Trihexyphenidyl	1974
Psychopharmacology in the aged. Use of major psychotropic medications in treatment of the elderly: case examples. Journal of geriatric psychiatry, 1974, Volume: 7, Issue:2 Topics: Adjustment Disorders; Aged; Alzheimer Disease; Amitriptyline; Benztropine; Bipolar Disorder; Catatonia; Chlorpromazine; Dementia; Female; Humans; Lithium; Male; Mental Disorders; Psychopharmacology; Psychoses, Substance-Induced; Thioridazine; Tranquilizing Agents; Trifluoperazine	1974
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins. Neuropharmacology, 1974, Volume: 13, Issue:2 Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl	1974
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium	1973
Drug-induced heat stroke. Anesthesiology, 1973, Volume: 39, Issue:3 Topics: Adult; Antiparkinson Agents; Benztropine; Chlorpromazine; Heat Exhaustion; Humans; Male; Mental Disorders; Middle Aged; Tropanes	1973
Mutism and hyperthermia in a patient treated with neuroleptics. The Medical journal of Australia, 1973, Aug-04, Volume: 2, Issue:5 Topics: Adult; Antiparkinson Agents; Benztropine; Chlorpromazine; Fever; Haloperidol; Humans; Male; Mutism; Tropanes	1973
Combinations of antidepressant drugs in the treatment of depressive illness. Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:5 Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Benztropine; Canada; Chlorpromazine; Depression; Dibenzazepines; Diphenhydramine; Drug Synergism; Drug Therapy, Combination; Electroconvulsive Therapy; Evaluation Studies as Topic; Female; Humans; Male; Methaqualone; Middle Aged; Phenelzine; Retrospective Studies; Sleep; Tranylcypromine	1973
Drug-induced experimental Parkinsonism. Neuropharmacology, 1973, Volume: 12, Issue:8 Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Drug; Electromyography; Motor Neurons; Parkinson Disease; Parkinson Disease, Secondary; Phenothiazines; Rabbits; Rats; Reserpine; Tetanus; Time Factors; Tremorine; Trifluoperazine	1973
Antagonism of the effects of chlorpromazine and morphine on dopamine metabolism by GABA. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1 Topics: Acetates; Aminobutyrates; Animals; Apomorphine; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxylamines; Male; Methyltyrosines; Morphine; Rats	1974
The dopamine-releasing actions of neuroleptics and ethanol. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1 Topics: Animals; Benztropine; Calcium; Caudate Nucleus; Chlorpromazine; Dopamine; Drug Synergism; Ethanol; Haloperidol; In Vitro Techniques; Male; Pimozide; Rats; Reserpine; Synaptosomes; Tranquilizing Agents; Tritium	1974
The rabbit syndrome. A peculiar extrapyramidal reaction. Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:2 Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; Masticatory Muscles; Middle Aged; Mouth; Movement Disorders; Perphenazine; Procyclidine; Reserpine; Schizophrenia; Syndrome; Tranquilizing Agents; Trifluoperazine; Trihexyphenidyl	1972
Drug-induced heat stroke. Canadian Medical Association journal, 1983, Apr-15, Volume: 128, Issue:8 Topics: Adult; Benztropine; Body Temperature Regulation; Chlorpromazine; Heat Exhaustion; Humans; Male; Psychotropic Drugs; Schizophrenia; Thermosensing	1983
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain. Journal of neurochemistry, 1982, Volume: 38, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine	1982
Small left colon syndrome associated with maternal ingestion of psychotropic drugs. The Journal of pediatrics, 1980, Volume: 97, Issue:2 Topics: Benztropine; Biperiden; Chlorpromazine; Colonic Diseases, Functional; Doxepin; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intestinal Obstruction; Male; Pregnancy; Pregnancy Complications; Psychotropic Drugs; Schizophrenia; Thiothixene	1980