chlorpromazine and benzocaine

chlorpromazine has been researched along with benzocaine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Ahman, M; Holmén, AG; Wan, H1
Gozalbes, R; Pineda-Lucena, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Koblin, DD; Lester, HA1
DeStefano, MJ; Rabinovitch, M1
Enyeart, JJ; Hinkle, PM; Phillips, WJ1
Stewart, JT; Wilkin, RE1
Bohn, E; Kunze, H; Vogt, W1
Malone, MH; Trottier, RW1
Suzuki, K; Tokura, Y; Yamazaki, S1

Other Studies

13 other study(ies) available for chlorpromazine and benzocaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques.
    Molecular pharmacology, 1979, Volume: 15, Issue:3

    Topics: Acetylcholine; Anesthetics, Local; Animals; Benzocaine; Chlorpromazine; Dibucaine; Electric Conductivity; Electric Organ; Electrophorus; In Vitro Techniques; Kinetics; Lidocaine; Membrane Potentials; Procaine; Receptors, Cholinergic; Receptors, Nicotinic; Tetracaine

1979
Cell shape changes induced by cationic anesthetics.
    The Journal of experimental medicine, 1976, Feb-01, Volume: 143, Issue:2

    Topics: Anesthetics, Local; Animals; Benzocaine; Cell Adhesion; Cell Fusion; Cell Membrane; Cell Movement; Chlorpromazine; Culture Media; Dibucaine; Edetic Acid; Egtazic Acid; Female; HEPES; Lidocaine; Macrophages; Mice; Prilocaine; Pseudopodia; Structure-Activity Relationship; Tetracaine; Tetrodotoxin; Tromethamine

1976
Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:9

    Topics: Anesthetics, Local; Animals; Benzocaine; Chlordiazepoxide; Chlorpromazine; Dibucaine; Hydrogen-Ion Concentration; Imipramine; Lidocaine; Pituitary Gland; Procaine; Prolactin; Propranolol; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetracaine; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil

1989
Determination of sulfonamides and local anesthetics with 9=chloroacridine by quenching fluorometry.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:3

    Topics: 4-Aminobenzoic Acid; Acridines; Aminobenzoates; Anesthetics, Local; Aspirin; Benzocaine; Chlorine; Chlorpromazine; Ephedrine; Fluorescence; Methods; Oxazepam; Phenobarbital; Spectrometry, Fluorescence; Sulfamethizole; Sulfamethoxypyridazine; Sulfanilamides; Sulfathiazoles; Sulfisoxazole; Sulfonamides; Tetracycline

1972
Effects of local anaesthetics on prostaglandin biosynthesis in vitro.
    Biochimica et biophysica acta, 1974, Sep-19, Volume: 360, Issue:3

    Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Benzocaine; Calcium; Carbon Radioisotopes; Cattle; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Dibucaine; Edetic Acid; Kinetics; Lidocaine; Linoleic Acids; Male; Mepivacaine; Oleic Acids; Phosphatidylethanolamines; Phospholipases; Procaine; Prostaglandins; Seminal Vesicles; Sheep; Snakes; Species Specificity; Tetracaine; Triglycerides

1974
Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Benzocaine; Bradykinin; Burns; Chlorpromazine; Dose-Response Relationship, Drug; Edema; Female; Flufenamic Acid; Forelimb; In Vitro Techniques; Indomethacin; Male; Morphine; Phenylbutazone; Plant Extracts; Quinolizines; Rats; Reserpine; Tetrabenazine; Time Factors; Uterus

1973
Expression of T-cell cytokines in challenged skin of murine allergic contact photosensitivity: low responsiveness is associated with induction of Th2 cytokines.
    Journal of dermatological science, 2000, Volume: 23, Issue:2

    Topics: Allergens; Animals; Benzocaine; Chlorpromazine; Cytokines; Dermatitis, Contact; Female; Gene Expression Regulation; Interferon-gamma; Interleukin-2; Interleukin-4; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Reverse Transcriptase Polymerase Chain Reaction; Salicylanilides; Skin; Species Specificity; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Th2 Cells

2000