chlorpromazine and azathioprine

chlorpromazine has been researched along with azathioprine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (4.76)29.6817
2010's13 (61.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dubois, EL1
Knoblauch, M1
Lusins, JO; Szilagyi, PA1
Funk, C; Knoblauch, M; Lämmli, J1
Hockwin, O; Koch, HR1
Najarian, JS; Toledo-Pereyra, LH1
Fehér, J; François, J1

Reviews

3 review(s) available for chlorpromazine and azathioprine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Anticonvulsants; Antihypertensive Agents; Antitubercular Agents; Azathioprine; California; Chlorpromazine; Complement System Proteins; Contraceptives, Oral, Synthetic; DNA; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neutrophils; Phenothiazines; Pregnancy; Procainamide

1975
[Drug induced liver disease (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9

    Topics: Azathioprine; Bile Acids and Salts; Bilirubin; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Collagen; Contraceptives, Oral, Hormonal; Enzyme Induction; Female; Humans; Isoniazid; Male; Pharmaceutical Preparations

1978

Other Studies

18 other study(ies) available for chlorpromazine and azathioprine

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Clinical features of chorea associated with systemic lupus erythematosus.
    The American journal of medicine, 1975, Volume: 58, Issue:6

    Topics: Adult; Azathioprine; Blood Sedimentation; Chlorpromazine; Chorea; Female; Haloperidol; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Prednisone; Recurrence

1975
[Drug-induced liver diseases].
    Gastroenterologische Fortbildungskurse fur die Praxis, 1975, Volume: 5

    Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Dihydroxyphenylalanine; Enzyme Induction; Fatty Liver; Female; Granuloma; Halothane; Hepatomegaly; Humans; Male; Middle Aged; Oxyphenisatin Acetate; Pregnancy; Sulfonamides; Tetracycline

1975
[Iatrogenic cataracts].
    Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42

    Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimethyl Sulfoxide; Drug-Related Side Effects and Adverse Reactions; Environmental Health; Histamine H1 Antagonists; Humans; Phenelzine; Piperazines; Thiotepa; Urea

1974
Preservation of the small intestine for allotransplantation.
    Surgery, gynecology & obstetrics, 1973, Volume: 137, Issue:3

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Body Fluids; Body Weight; Chloramphenicol; Chlorpromazine; Dogs; Female; Graft Rejection; Intestinal Absorption; Intestine, Small; Kanamycin; Male; Mesenteric Vascular Occlusion; Methylprednisolone; Neomycin; Perfusion; Postoperative Complications; Preservation, Biological; Transplantation, Homologous; Xylose

1973
The effect of azathioprine and chlorpromazine on corneal regeneration.
    Experimental eye research, 1972, Volume: 14, Issue:1

    Topics: Alkalies; Animals; Azathioprine; Birefringence; Burns, Chemical; Chlorpromazine; Cornea; Drug Combinations; Eye Burns; Fibroblasts; Injections, Intravenous; Leukocytes; Organoids; Rabbits; Regeneration

1972