chlorpromazine and apomorphine

chlorpromazine has been researched along with apomorphine in 252 studies

Research

Studies (252)

TimeframeStudies, this research(%)All Research%
pre-1990217 (86.11)18.7374
1990's18 (7.14)18.2507
2000's7 (2.78)29.6817
2010's10 (3.97)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P1
George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH1
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P1
Chrzanowski, FA; Maryanoff, BE; McGrogan, BA1
Andrews, PR; Craik, DJ; Martin, JL1
Brougham, LR; Ellefson, CR; Miller, A; Prodan, KA1
Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF1
Emms, F; Freedman, SB; Knowles, MR; Marwood, R; McAllister, G; Patel, S; Seabrook, GR1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J1
Causa, P; Coscia, L; Giuliani, E; Nunziata, A1
Bronaugh, RL; Goldstein, M1
Amico, DJ; Calne, DB; Klawans, HL1
Laduron, PM; Niemegeers, CJ1
Dismukes, K; Mulder, AH1
Fowler, PJ; Kaiser, C; Macko, E; Sarau, H; Tedeschi, DH; Zirkle, CL1
Di Chiara, G; Loddo, P; Spano, PF; Tonon, GC; Trabucchi, M1
Matthysse, S1
Bioulac, B; Boulard, G; Puil, E; Vincent, JD1
Bo, P; Savoldi, F; Tartara, A2
Maeno, H; Sano, K; Usuda, S1
Brown, IR; Heikkila, JJ1
Desiles, M; Puech, AJ; Rips, R1
Bellodi, L; Fabio, G; Rugarli, C; Sacchetti, E; Scorza-Smeraldi, R; Smeraldi, E1
Abdel-Halim, MS; Anggård, E; Sjöquist, B1
Atamer-Simşek, S; Keyer-Uysal, M; Koyuncuoğlu, H2
Doherty, J; Fang, VS; Fessler, RG; Meltzer, HY; Simonovic, M1
Arushanian, EB; Avakian, RM2
Carlson, HE; Goodlett, RE; Hershman, JM; Levy, CL; Sowers, JR; Tourtellotte, WW1
Brown, JH; Makman, MH; Mishra, RK1
Jackson, DM1
Bucher, MB; Schorderet, M1
Gaillard, JM; Kafi, S1
Kretzschmar, R; Otto, J; Teschendorf, HJ; Worstmann, W1
Dinnendahl, V; Gumulka, SW; Schönhöfer, PS; Stock, K1
Biggio, G; Guidotti, A1
Davis, JN; Hoyler, E; Leefkowitz, RJ; Strittmatter, WJ1
Nakamura, K; Oikawa, Y; Shimokawa, Y1
Extein, I; Goodwin, FK; Lo, C; Schoenfeld, RI1
Beaujouan, JC; Glowinski, J; Guyenet, PG; Javory, AF; Rossier, BJ1
Agid, Y; Beaujouan, JC; Glowinski, J; Guyenet, PG; Javoy, F1
Cannon, JG; Ilhan, M; Long, JP; Nichols, DE1
Bratfos, O1
Dent, R; Guyda, H; Tolis, G1
Chau-Pham, T; Dewey, WL; Martin, BR; Prnage, AJ1
Baudry, M; Guyon, A; le Sellin, M; Martres, MP; Morgat, JL; Schwartz, JC1
D'amico, DJ; Klawans, HL; Nausieda, PA; Weiner, WJ1
Arushanian, EB; Avakian, RM; Kozlov, VKh; Pergaev, AP1
Argiolas, A; Fadda, F; Gessa, GL; Klimek, V; Serra, G1
Andreas, K; Kraft, H; Kraft, U1
Andreas, K; Lehmann, K1
Lal, S; Sourkes, TL; Symes, AL; Tsang, D; Young, SN1
Czlonkowski, A; Herz, A; Höllt, V1
Honda, F; Kato, R; Noguchi, H; Satoh, H; Satoh, Y; Shimomura, K; Uchida, S1
Cuparencu, B; Feszt, G; Kun, I; Orbán, I1
Lassen, JB1
Horowski, R1
Banovac, K; Petek, M; Sekso, M; Solter, M; Vizner, B1
Martin, WR; Shannon, HE; Silcox, D1
Pepeu, G1
Eliasson, M; Meyerson, BJ1
Ishida, R; Ito, K; Kowa, Y; Nurimoto, S; Shintomi, K; Yamamura, M1
Pletscher, A; Saner, A1
Cuparencu, B; Sandor, V1
Bianchi, S; Consolo, S; Ghezzi, D; Ladinsky, H1
Avakian, RM1
Roufogalis, BD; Thornton, M; Wade, DN1
Carnmalm, B; Johansson, L; Ogren, SO; Rämsby, S; Ross, SB; Stjernström, NE1
Borsy, J; Dunai-Kovács, Z; Székely, JI1
Niemegeers, CJ; Wauquier, A1
Pakszys, W1
Holmgren, B; Urbá-Holmgren, R; Valdés, M1
Hasegawa, K; Sakai, U1
Calil, HM; Silva, MT1
Carlsson, A; Kehr, W; Lindqvist, M1
Cannon, JG; Heintz, S; Kim, J; Long, JP1
Boucher, R; Dankova, J; Poirier, LJ1
Kelly, PH; Miller, RJ1
Enero, MA; Langer, SZ1
Shintomi, K; Yamamura, M1
Chen, PO; Endo, T; Matsuda, H; Nishimori, T; Sato, K; Shibuya, T1
Asper, H; Bürki, HR; Ruch, W; Sayers, AC1
Herr, F; Voith, K1
Poignant, JC; Rismondo, N1
Kojima, T; Koyama, Y; Marumo, H; Nakamura, N; Shiozaki, S1
Marsden, CD; Pycock, C; Tarsy, D1
Gershanik, O; Luquin, MR; Obeso, JA; Scipioni, O; Vaamonde, J1
Cook, L; Rohrbach, KW; Tam, SW1
Ben-Shachar, D; Pinhassi, B; Youdim, MB1
Fujimura, H; Mibu, H; Niwa, M; Nozaki, M; Tsurumi, K1
Herman, ZS; Huzarska, M; Kmieciak-Kolada, K; Kowalski, J1
Harajiri, S; Nishi, S; Yamada, S; Yokoo, H1
Arbilla, S; Dahl, SG; Langer, SZ; Nowak, JZ1
Dóda, M1
Carvey, P; Goetz, CG; Klawans, HL; Tanner, CM1
Liepmann, H; Muesch, HR; Ruhland, M1
Bond, A; Neal, H1
Johnson, KM; Snell, LD1
Salama, AI; Saller, CF1
Fujita, M; Horikomi, K1
Chang, YA; Farooqui, T; Harrold, MW; Miller, DD; Uretsky, N; Wallace, LJ; Wallace, RA1
Hong, M; Jenner, P; Kilpatrick, GJ; Marsden, CD1
Butterfield, J; Garrard, JM; Peterson, DA1
Munro, AD1
Roy, RK; Uppal, RP1
Brus, R; Gmerczyński, T; Makowska, B; Stanosek, B1
De Witte, P; Gewiss, M; Goldman, S; Roques, B; Swanet, E; Vanderhaeghen, JJ1
Gerber, R; Gerhardt, S; Liebman, JM1
Trulson, ME1
Randall, PK; Yurek, DM1
Maeda, H; Maki, S; Sato, T1
Akahori, F; Arai, S; Ichimura, T; Masaoka, T1
Maxwell, DR; Read, MA; Sumpter, EA1
Timmerman, H; van Beek, MC1
McKenzie, GM; Sadof, M1
Morgenroth, VH; Roth, RH; Walters, JR1
Gylys, JA; Holmes, SW1
Antonaccio, MJ; Robson, RD1
Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A1
Andén, NE1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
Lotti, VJ1
Horst, WD; Schlosser, W; Sigg, EB; Spiegel, HE1
Lahti, RA; McAllister, B; Wozniak, J1
Bartholini, G; Gadea-Ciria, M; Lloyd, KG; Stadler, H1
Brown, JH; Makman, MH1
Willems, JL1
Hoffer, BJ; Siggins, GR; Ungerstedt, U1
Weissman, A1
Dresse, A; Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Pinchard, A; Schaper, WK; Schellekens, KH; van Nueten, JM; Verbruggen, FJ1
Büch, O; Delini-Stula, A; Eigenmann, R; Levin, P; Theobald, W1
Griffith, JF; Weaver, JE1
Stille, G1
Sourkes, TL1
Greengard, P; Kebabian, JW; Petzold, GL1
McKenzie, GM2
Sethy, VH; Van Woert, MH2
Collier, HO; McDonald-Gibson, WJ; Saeed, SA1
Eigeman, L; Vaatstra, WJ1
Belluzzi, JD; Ritter, S; Stein, L; Wise, CD1
Clemens, JA; Sawyer, BD1
Baldessarini, RJ; Tarsy, D2
Honma, T; Inaba, S; Kitagawa, S; Ono, K; Sasajima, K; Yamamoto, H1
Bass, P; Kennedy, JA; Wiley, JN1
Bieger, D; Hornykiewicz, O; Larochelle, L1
Hornykiewicz, O; Kuschinsky, K2
Klawans, HL; Rubovits, R1
Adejoh, PO; Osuide, G1
De la Vega, CE; Friesen, HG; Lal, S; Sourkes, TL1
Masur, J; Terada, CW1
Hackman, R; Neuvonen, PJ; Pentikainen, P; Vapaatalo, H1
Lahti, RA; Losey, EG1
Gessa, GL; Tagliamonte, A1
Cheng, HC; Long, JP1
Cecchetti, G; Dolfini, E; Garattini, S; Jori, A; Monti, E1
Koch, MH1
Dandiya, PC; Patni, SK1
Baran, L; Maj, J; Sarnek, J; Sowińska, H1
Clemens, JA; Sawyer, BD; Smalstig, EB1
Ogasawara, T; Ogawa, N; Ueki, S1
Cecchetti, G; Ghezzi, D; Jori, A; Samanin, R1
Soyka, D1
Andén, NE; Butcher, LL; Butcher, SG; Fuxe, K; Ungerstedt, U1
Pfeffer, M; Rubin, AA; Yen, HC1
Kamioka, T; Kobayashi, S; Suzuki, Y; Tachikawa, R; Takagi, H1
Buser, P; Cook, L; Giurgea, C; Jacobsen, E; Ray, OS; Richelle, M; Silverman, AP; Stein, L; Votava, Z1
Barnett, A; Goldstein, J; Taber, RI1
Fowler, PJ; Garvey, E; Kaiser, C; Nodiff, EA; Pavloff, AM; Saggiomo, AJ; Tedeschi, DH; Zirkle, CL1
Dlabac, A; Metys, J; Metysová, J1
Dhasmana, KM; Dhawan, KN; Dixit, KS; Gupta, GP1
Amano, Y; Fukuda, N; Takaori, S1
Nikki, P1
Enmin, GM1
Dyntarová, H; Votava, Z1
Burkman, AM; Van Tyle, WK1
Senault, B1
Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH1
Laplace, JP; Ruckebusch, Y1
Boissier, JR; Giudicelli, JF; Simon, P1
Bagdon, RE; Banziger, R; Boris, A; Moe, RA; Randall, LO; Schallek, W; Scheckel, CL; Stefko, PL1
Haas, H; Jantos, W1
Dhawan, BN; Gupta, GP1
Morpurgo, C; Theobald, W1
Ackermann, H; Eichenberger, E; Lauener, H; Stille, G1
Fellows, EJ; Fujita, T; Leonard, CA; Tedeschi, DH; Zirkle, CL1
Koe, BK; Tenen, SS; Weissman, A1
Varshamov, IuL1
Schelkunov, EL1
Kowner, A; Szmigielski, A1
Glassman, HN; Glassman, RB1
Kenny, M; Leonard, BE1
Gale, K; Stoff, DM1
Spaan, SJ; van Es, TP; Westerink, BH1
Fukuda, T; Kurihara, M; Setoguchi, M; Tsumagari, T1
Carvey, P; Goetz, CG; Klawans, HL1
Beal, MF; Martin, JB1
Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO1
Galliani, G; Glässer, A; Restelli, A; Rosina, R1
Kameyama, T; Nagasaka, M2
Dashputra, PG; Hemnani, TJ1
Fink, H; Morgenstern, R; Oelssner, W1
Nomoto, T; Uchida, Y1
Atamer-Simşek, S; Keyer-Uysal, M; Koyuncuoğlu, H; Sağduyu, H1
Dlabac, A; Kazdová, E; Metys, J; Metysová, J; Valchár, M1
Kleinrok, Z; Szurska, G1
Spaan, SJ; Westerink, BH1
Zapata, P; Zuazo, A1
Delanoy, RL; Dunn, AJ1
Carvey, P; Hitri, A; Klawans, HL; Nausieda, PA; Weiner, WJ1
Angeby, T; Haglund, L; Köhler, C; Ogren, SO1
Takagi, A1
Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT1
Evans, DL; Figur, LM; Lahti, RA; Stratman, NC1
Farooqui, T; Markovich, K; Miller, D; Uretsky, N; Wallace, L1
Horisaka, K; Sugimoto, Y; Yamada, J1
Awasthi, PK; Chattaraj, T; Garg, HK; Hasan, M; Singhal, KC; Srivastava, VK1
Mok, EY; Munro, AD1
Gálfi, M; Janáky, T; Juhász, A; László, FA; Prohászka, G; Tóth, R; Varga, C1
Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J1
BORISON, HL; BRAND, ED; GOODMAN, LS; HARRIS, TD1
ISAACS, B; MACARTHUR, JG1
MADJEREK, Z; STERN, P1
AHMED, A1
TADDEI, I; TIEZZI, C1
LIN, FM; MA, WC; SUNG, CY1
CAHEN, R; PESSONNIER, A1
BHARGAVA, KP; CHANDRA, O1
SCHRAMM, H; THER, L1
JUSTIN-BESANCON, L; LAVILLE, C; THOMINET, M1
JUSTIN-BESANCON, L; LAVILLE, C1
NIXON, JW; QUINN, JT1
Elekes, K; Filla, A; Hiripi, L1
Both, FL; Elisabetsky, E; Henriques, AT; Kerber, VA; Meneghini, L1
Copoglu, US; Dokuyucu, R; Erbas, O; Inanir, S; Kokacya, MH1
Adjei, S; Amoateng, P; Bekoe, EO; Karikari, TK; Kombian, SB; Kukuia, KKE; Osei-Safo, D1

Reviews

3 review(s) available for chlorpromazine and apomorphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacology and biochemistry of haloperidol.
    Proceedings of the Royal Society of Medicine, 1976, Volume: 69 suppl 1

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Brain Chemistry; Cattle; Chlorpromazine; Dogs; Drug Interactions; Emetics; Haloperidol; Homovanillic Acid; Humans; Mice; Rats; Receptors, Dopamine; Tranquilizing Agents

1976
Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Animals; Apomorphine; Butyrates; Calcium; Chloral Hydrate; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Electric Conductivity; Haloperidol; Halothane; Hydroxybutyrates; Lactones; Male; Medulla Oblongata; Models, Biological; Neurons; Norepinephrine; Pargyline; Promethazine; Rats; Time Factors; Tyrosine 3-Monooxygenase; Vas Deferens

1974

Trials

2 trial(s) available for chlorpromazine and apomorphine

ArticleYear
[The effect of psychopharmacological drugs and other central nervous system effecting drugs on experimental nystagmus].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1968, Volume: 36, Issue:9

    Topics: Amitriptyline; Apomorphine; Aporphines; Barbiturates; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Diazepam; Dimenhydrinate; Eye Movements; Fluphenazine; Haloperidol; Humans; Imipramine; Schizophrenia; Thioridazine; Triflupromazine

1968
[Features of active anti-alcohol therapy of patients who have suffered alcoholic psychoses].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:6

    Topics: Acute Disease; Adult; Alcoholism; Apomorphine; Calcium; Cardiovascular Diseases; Chlorpromazine; Disulfiram; Emetics; Gluconates; Humans; Insulin; Magnesium; Male; Methotrimeprazine; Middle Aged; Placebos; Psychoses, Alcoholic; Psychotherapy; Sulfhydryl Compounds; Thiamine; Vitamins

1969

Other Studies

247 other study(ies) available for chlorpromazine and apomorphine

ArticleYear
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection

1992
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
    Nature, 1991, Apr-18, Volume: 350, Issue:6319

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection

1991
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
    Nature, 1990, Sep-13, Volume: 347, Issue:6289

    Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution

1990
The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Animals; Brain; Butaclamol; Dibenzocycloheptenes; Humans; Receptors, Dopamine

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Synthesis of 8-aryltetrahydroisoquinolines as dopamine antagonists and evaluation for potential neuroleptic activity.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:9

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Binding, Competitive; Cattle; Central Nervous System; Dopamine; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Isoquinolines; Male; Mice; Rats; Receptors, Dopamine

1980
Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
    Journal of medicinal chemistry, 1993, Apr-16, Volume: 36, Issue:8

    Topics: Animals; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship

1993
Expression and pharmacological characterization of the human D3 dopamine receptor.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Animals; Binding, Competitive; Cells, Cultured; CHO Cells; Cricetinae; Dopamine; Dopamine Antagonists; GTP-Binding Proteins; Guanine Nucleotides; Humans; Potassium Channels; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Second Messenger Systems; Sulpiride

1994
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines

2019
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines

2019
Pharmacological properties of new neuroleptic compounds.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:9

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Blood Pressure; Chlordiazepoxide; Chlorpromazine; Dibenzoxepins; Drug Evaluation, Preclinical; Epinephrine; Guinea Pigs; Histamine H1 Antagonists; Humans; Lethal Dose 50; Male; Mice; Motor Activity; Muscle Contraction; Piperazines; Rats; Sleep; Time Factors; Tranquilizing Agents

1975
The effect of various chlorpromazine derivatives on the apomorphine-elicited inhibition of synaptosomal tyrosine hydroxylase activity.
    Psychopharmacology communications, 1975, Volume: 1, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Corpus Striatum; In Vitro Techniques; Male; Rats; Synaptosomes; Tyrosine 3-Monooxygenase

1975
Altered hypothermic responsivness to (+)-amphetamine.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:2

    Topics: Animals; Apomorphine; Body Temperature; Chlorpromazine; Depression, Chemical; Dextroamphetamine; Drug Tolerance; Guinea Pigs; Male; Pimozide

1976
Effects of neuroleptics on release of 3H-dopamine from slices of rat corpus striatum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Fluphenazine; Haloperidol; Male; Rats; Spiperone

1977
Pharmacological evaluation of clomacran, a new potent psychotropic agent.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Acridines; Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Basal Ganglia Diseases; Behavior, Animal; Chlorpromazine; Chlorprothixene; Conditioning, Psychological; Corpus Striatum; Dogs; Dopamine; Female; Haplorhini; Hemodynamics; Humans; Lethal Dose 50; Macaca mulatta; Male; Mice; Motor Activity; Rage; Rats; Reaction Time; Stereotyped Behavior; Trifluoperazine

1977
Dopamine-stimulated adenylate cyclase in rat substantia nigra: localization and effects of neuroleptics.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Dopamine; Fluphenazine; Haloperidol; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Rats; Substantia Nigra; Sulpiride

1977
A theory of the relation between dopamine and attention.
    Journal of psychiatric research, 1978, Volume: 14, Issue:1-4

    Topics: Adrenergic Agonists; Amphetamine; Apomorphine; Attention; Chlorpromazine; Dopamine; Dopamine Antagonists; Eye Movements; Humans; Receptors, Dopamine; Stereotyped Behavior

1978
Effects of dopamine agonists on neurones in the caudate nucleus and cerebral cortex of cats chronically treated with neuroleptics.
    Neuropharmacology, 1978, Volume: 17, Issue:11

    Topics: Animals; Antipsychotic Agents; Apomorphine; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Dopamine; Haloperidol; Neurons; Piribedil

1978
Antagonism between dopaminergic and neuroleptic drugs. I. Acute administration.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:7

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arousal; Bromocriptine; Central Nervous System; Chlorpromazine; Dibenzothiazepines; Electroencephalography; Haloperidol; Neurotransmitter Agents; Piribedil; Rabbits; Reserpine

1979
Antagonism between dopaminergic and neuroleptic drugs. II. Chronic administration.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:7

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arousal; Bromocriptine; Central Nervous System; Chlorpromazine; Dibenzothiazepines; Electroencephalography; Haloperidol; Neurotransmitter Agents; Piribedil; Rabbits; Time Factors

1979
Pharmacological and biochemical studies on a new potential neuroleptic, N-(1-benzyl-3-pyrrolidinyl)-5-chloro-2-methoxy-4-methylaminobenzamide (YM-08050).
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 241, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Catalepsy; Chlorpromazine; Dogs; Dopamine; Drug Interactions; Female; Haloperidol; Humans; Male; Methamphetamine; Mice; Physostigmine; Rats; Stereotyped Behavior; Synaptic Membranes

1979
Disaggregation of brain polysomes after LSD in vivo. Involvement of LSD-induced hyperthermia.
    Neurochemical research, 1979, Volume: 4, Issue:6

    Topics: Aging; Animals; Apomorphine; Body Temperature; Brain; Chlorpromazine; Fever; Kidney; Lysergic Acid Diethylamide; Male; Pizotyline; Poly A; Polyribosomes; Rabbits; RNA, Messenger; Stress, Physiological

1979
Is a dopaminergic system involved in thyrotropin releasing hormone induced hyperthermia and in its potentiation by amphetamine?
    Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4

    Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Chlorpromazine; Dopamine; Dopamine Agents; Female; Fever; Haloperidol; Levodopa; Methyltyrosines; Mice; Neurotransmitter Agents; p-Chloroamphetamine; Pimozide; Thyrotropin-Releasing Hormone

1979
Interference between anti-HLA antibodies and adrenergic receptor-binding drugs.
    Tissue antigens, 1977, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Antibodies; Apomorphine; Binding Sites, Antibody; Chlorpromazine; Cross Reactions; Dopamine; Epitopes; Female; Haloperidol; Histocompatibility Antigens; HLA Antigens; Humans; Immune Sera; Lymphocytes; Propranolol; Sulpiride

1977
Prostaglandin synthesis inhibition and monoamine metabolites in the rat brain.
    Prostaglandins, 1979, Volume: 18, Issue:6

    Topics: Animals; Apomorphine; Brain; Chlorpromazine; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Indomethacin; Male; Methoxyhydroxyphenylglycol; Morphine; Olfactory Bulb; Phenylacetates; Rats

1979
Effects of continuous and acute administration of small doses of apomorphine, alone or in combination with chlorpromazine, on the brain monoamines and free amino acid levels in the rat.
    Psychopharmacology, 1979, Volume: 66, Issue:2

    Topics: Amino Acids; Animals; Apomorphine; Biogenic Amines; Brain Chemistry; Chlorpromazine; Dopamine; Drug Interactions; Norepinephrine; Rats; Serotonin

1979
Lysergic acid diethylamide: evidence for stimulation of pituitary dopamine receptors.
    Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Fenclonine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Methysergide; Pituitary Gland; Prolactin; Quipazine; Rats; Receptors, Dopamine; Stimulation, Chemical

1977
[Participation of monoaminergic mechanisms and the striatum in the development of "petit mal" induced by corazole].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Amines; Chlorpromazine; Corpus Striatum; Drug Interactions; Electroencephalography; Epilepsy, Absence; Fenclonine; Haloperidol; Levodopa; Male; Pentylenetetrazole; Rats

1978
Growth hormone and prolactin secretion in Huntington's disease.
    Life sciences, 1979, Feb-19, Volume: 24, Issue:8

    Topics: Adult; Aged; Apomorphine; Chlorpromazine; Female; Growth Hormone; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors

1979
Cyclic AMP in retina and caudate nucleus: influence of dopamine and other agents.
    Advances in cyclic nucleotide research, 1975, Volume: 5

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Cyclic AMP; Dopamine; Epinephrine; Ergotamine; Fluphenazine; Haloperidol; Isoproterenol; Lysergic Acid Diethylamide; Norepinephrine; Ouabain; Phentolamine; Potassium; Propranolol; Retina; Species Specificity

1975
Beta-phenylethylamine and locomotor activity in mice. Interaction with catecholaminergic neurones and receptors.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:4

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Chlorpromazine; Ditiocarb; Drug Interactions; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Neurons; Perphenazine; Phenethylamines; Phenoxybenzamine; Phentolamine; Pimozide; Propranolol; Receptors, Drug; Reserpine

1975
Dopamine- and apomorphine-sensitive adenylate cyclase in homogenates of rabbit retina.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 288, Issue:1

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Chlorpromazine; Cyclic AMP; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Epinephrine; Haloperidol; In Vitro Techniques; Isoproterenol; Phentolamine; Rabbits; Receptors, Drug; Retina; Stimulation, Chemical; Subcellular Fractions

1975
[Effect of catecholaminergic substances on the proconvulsive properties of the caudate nucleus].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 80, Issue:8

    Topics: Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Chlorpromazine; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Haloperidol; Levodopa; Male; Methyltyrosines; Neural Inhibition; Rats; Seizures; Sympathomimetics; Synaptic Transmission; Time Factors

1975
Brain dopamine receptors and sleep in the rat: effects of stimulation and blockade.
    European journal of pharmacology, 1976, Volume: 38, Issue:2

    Topics: Animals; Apomorphine; Brain; Chlorpromazine; Dopamine; Electroencephalography; Electromyography; Male; Rats; Receptors, Drug; Sleep; Sleep, REM; Spiperone; Time Factors

1976
[Pharmacological investigations of 4'-fluoro-4-(4-methyl-peperidono)-butyrophenone with respect to its sedative and sleep-inducing properties (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:6

    Topics: Animals; Apomorphine; Arousal; Butyrophenones; Chlorpromazine; Electroencephalography; Female; Humans; Mice; Motor Activity; Muscle Tonus; Rabbits; Rats; Sleep; Sleep, REM; Stereotyped Behavior; Thioridazine

1976
Dopaminergic stimulants and cyclic nucleotides in mouse brain. Effects of dopaminergic antagonists, cholinolytics, and GABA agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 295, Issue:1

    Topics: Aminobutyrates; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Atropine; Brain; Butyrophenones; Cerebellum; Chlorpromazine; Cyclic GMP; Diazepam; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Medial Forebrain Bundle; Mice; Stereotyped Behavior

1976
Regulation of cyclic GMP in cerebellum by a striatal dopaminergic mechanism.
    Nature, 1977, Jan-20, Volume: 265, Issue:5591

    Topics: Animals; Apomorphine; Basal Ganglia; Cerebellar Cortex; Chlorpromazine; Corpus Striatum; Cyclic GMP; Dibenzocycloheptenes; Haloperidol; Male; Neural Pathways; Quinolizines; Rats; Receptors, Dopamine

1977
[3H]dihydroergocryptine binding in rat brain.
    Brain research, 1977, Aug-26, Volume: 132, Issue:2

    Topics: Animals; Apomorphine; Binding, Competitive; Cerebellum; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dihydroergotoxine; Dopamine; Epinephrine; Haloperidol; Hypothalamus; Kinetics; Male; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord

1977
[Influence of clonazepam, an anticonvulsant benzodiazepine drug, on the rat brain monoamine containing neurons especially on dopaminergic neurons (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:2

    Topics: Acetylcholinesterase; Animals; Apomorphine; Benzodiazepinones; Brain; Brain Chemistry; Chlorpromazine; Choline O-Acetyltransferase; Clonazepam; Cyclic AMP; Dopamine; Humans; Male; Methamphetamine; Norepinephrine; Rats; Serotonin; Stereotyped Behavior

1978
Dopamine-mediated behavior produced by the enkephalin analogue FK 33-824.
    Psychiatry research, 1979, Volume: 1, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Male; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid; Stereotyped Behavior

1979
Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system.
    Brain research, 1975, Feb-07, Volume: 84, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Chemistry Techniques, Analytical; Chlorpromazine; Corpus Striatum; Depression, Chemical; Haloperidol; Hippocampus; Hydroxydopamines; Male; Parietal Lobe; Phenothiazines; Pimozide; Rats; Stimulation, Chemical; Tranquilizing Agents

1975
Dopamine receptors and cholinergic neurons in the rat neostriatum.
    Advances in neurology, 1975, Volume: 9

    Topics: Acetylcholine; Animals; Apomorphine; Chlorpromazine; Corpus Striatum; Depression, Chemical; Dopamine; Drug Antagonism; Haloperidol; Male; Phenothiazines; Pimozide; Putamen; Rats; Receptors, Drug; Stimulation, Chemical; Substantia Nigra

1975
Apomorphine-like effect of an aminotetralin on the linguomandibular reflex of the cat.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Animals; Apomorphine; Aporphines; Cats; Chlorpromazine; Depression, Chemical; Dopamine; Electric Stimulation; Female; Haloperidol; Heart Rate; Male; Mandible; Naphthols; Receptors, Drug; Reflex; Tongue

1975
[Pharmacotherapy for alcoholism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Nov-10, Volume: 95, Issue:31

    Topics: Adrenergic beta-Antagonists; Alcoholism; Antidepressive Agents; Apomorphine; Chlorpromazine; Humans; Lithium

1975
Opiates, prolactin, and the dopamine receptor.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:1

    Topics: Apomorphine; Bromocriptine; Chlorpromazine; Cyproheptadine; Heroin Dependence; Humans; Kinetics; Levodopa; Methadone; Morphine; Prolactin; Receptors, Dopamine

1978
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
    Life sciences, 1977, Feb-15, Volume: 20, Issue:4

    Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; Mice; Morphinans; Morphine; Pain; Pentobarbital; Rats; Substance Withdrawal Syndrome; Thyrotropin-Releasing Hormone

1977
[In vivo binding of tritiated agents in mouse brain].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1977, Oct-17, Volume: 285, Issue:9

    Topics: Animals; Apomorphine; Brain; Cerebellum; Chlorpromazine; Corpus Striatum; Haloperidol; Male; Mice; Pimozide; Tissue Distribution

1977
The specificity of neuroleptic- and methysergide-induced behavioral hypersensitivity.
    Psychopharmacology, 1977, Nov-24, Volume: 55, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; Humans; Male; Methysergide; Motor Activity; Receptors, Dopamine; Receptors, Serotonin; Stereotyped Behavior

1977
[Role of the catecholaminergic mechanisms and of the caudate nucleus in the development of generalized convulsions caused by the parenteral administration of penicillin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:7

    Topics: Animals; Apomorphine; Cats; Caudate Nucleus; Chlorpromazine; Electric Stimulation; Electroencephalography; Female; Haloperidol; Levodopa; Male; Penicillin G; Receptors, Adrenergic; Seizures; Time Factors

1979
Chronic treatment with antidepressants prevents the inhibitory effect of small doses of apomorphine on dopamine synthesis and motor activity.
    Life sciences, 1979, Jul-30, Volume: 25, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Caudate Nucleus; Chlorpromazine; Dopamine; Imipramine; Male; Mianserin; Motor Activity; Rats; Receptors, Dopamine

1979
[Effect of dopaminergic substances on the antinocifensive action of arecoline].
    Acta biologica et medica Germanica, 1979, Volume: 38, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Arecoline; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Synergism; Haloperidol; Male; Neurons; Pain; Rats; Spinal Cord

1979
[Pharmacological modification of evoked caudate nucleus potentials].
    Acta biologica et medica Germanica, 1979, Volume: 38, Issue:9

    Topics: Animals; Apomorphine; Arecoline; Atropine; Autonomic Agents; Caudate Nucleus; Chlorpromazine; Electric Stimulation; Evoked Potentials; Female; Gallamine Triethiodide; Putamen; Rats; Substantia Nigra

1979
Effect of chronic chlorpromazine administration or prior treatment with reserpine on brain apomorphine concentrations and apomorphine-induced sterotyped behaviour in the rat.
    European journal of pharmacology, 1977, May-15, Volume: 43, Issue:2

    Topics: Animals; Apomorphine; Behavior; Brain Chemistry; Chlorpromazine; Drug Interactions; Humans; Male; Motor Activity; Rats; Reserpine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors

1977
The demonstration in vivo of specific binding sites for neuroleptic drugs in mouse brain.
    Brain research, 1977, Jul-08, Volume: 130, Issue:1

    Topics: Animals; Apomorphine; Brain; Catalepsy; Chlorpromazine; Dibenzocycloheptenes; Dopamine; Haloperidol; Humans; Male; Mice; Piribedil; Quinolizines; Receptors, Dopamine; Receptors, Drug; Spiperone; Structure-Activity Relationship; Tranquilizing Agents

1977
Dopamine receptor blocking activity of sulpiride in the central nervous system.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:3

    Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Cerebral Ventricles; Chlorpromazine; Compulsive Behavior; Haloperidol; Humans; Injections, Intravenous; Male; Methamphetamine; Rats; Receptors, Dopamine; Sulpiride

1977
Effects of apomorphine combined with chlorpromazine and pimozide on the estrous cycle in rats.
    Endokrinologie, 1977, Volume: 70, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Diestrus; Estrus; Female; Metestrus; Pimozide; Pregnancy; Rats

1977
Inhibition of apomorphine-induced hypermotility in rats by chlorpromazine, perphenazine, thioridazine and melperone.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:3

    Topics: Animals; Apomorphine; Butyrophenones; Chlorpromazine; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Motor Activity; Perphenazine; Rats; Thioridazine; Time Factors

1977
A new method for automatic registration of stereotyped behaviour in the rat.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:12

    Topics: Animals; Antidepressive Agents, Tricyclic; Apomorphine; Behavior; Chlorpromazine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Haloperidol; Housing, Animal; Humans; Psychology, Experimental; Rats; Stereotyped Behavior; Time Factors

1978
The effect of dopaminergic drugs on pituitary hormone release in normal subjects.
    Acta medica Iugoslavica, 1977, Volume: 31, Issue:4

    Topics: Adult; Apomorphine; Bromocriptine; Chlorpromazine; Female; Humans; Levodopa; Pituitary Gland

1977
Lack of antiemetic effects of delta9-tetrahydrocannabinol in apomorphine-induced emesis in the dog.
    Life sciences, 1978, Jul-03, Volume: 23, Issue:1

    Topics: Animals; Antiemetics; Apomorphine; Chlorpromazine; Dogs; Dronabinol; Female; Male

1978
Drug effect on cholinergic mechanisms in the cerebral cortex.
    Annali dell'Istituto superiore di sanita, 1978, Volume: 14, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Cats; Cerebral Cortex; Chlorpromazine; Choline O-Acetyltransferase; Cholinergic Fibers; Levodopa; Nerve Endings; Rats; Receptors, Dopamine

1978
Comparison of the action of lysergic acid diethylamide and apomorphine on the copulatory response in the female rat.
    Psychopharmacology, 1976, Sep-29, Volume: 49, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Copulation; Dopamine; Female; Lysergic Acid Diethylamide; Motor Activity; Pimozide; Posture; Rats; Serotonin

1976
[Pharmacological studies of an antipschotic agent, penfluridol. (1). The central pharmacological actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:7

    Topics: Agonistic Behavior; Animals; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Catalepsy; Cats; Central Nervous System; Chlorpromazine; Conditioning, Classical; Cooperative Behavior; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Haloperidol; Haplorhini; Hexobarbital; Humans; Locomotion; Male; Methamphetamine; Mice; Parasympatholytics; Penfluridol; Piperidines; Rats

1976
Increase of striatal dopamine turnover by drugs: interference with granular storage or receptor blackade?
    European journal of pharmacology, 1977, Mar-21, Volume: 42, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Corpus Striatum; Cytoplasmic Granules; Dihydroxyphenylalanine; Dopamine; Haloperidol; Male; Rats; Receptors, Dopamine; Reserpine; Tranquilizing Agents

1977
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol

1977
Apparent lack of a dopaminergic-cholinergic link in the rat nucleus accumbens septi-tuberculum olfactorium.
    Brain research, 1977, Oct-28, Volume: 135, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Bromocriptine; Chlorpromazine; Clozapine; Dextroamphetamine; Haloperidol; Nucleus Accumbens; Olfactory Bulb; Pimozide; Piribedil; Rats; Receptors, Cholinergic; Receptors, Dopamine; Septal Nuclei

1977
[Effect of striatectomy on the course of corazole seizures in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 81, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Corpus Striatum; Electroencephalography; Female; Haloperidol; Levodopa; Male; Myoclonus; Pentylenetetrazole; Rats; Seizures

1976
Specificity of the dopamine sensitive adenylate cyclase for antipsychotic antagonists.
    Life sciences, 1976, Sep-15, Volume: 19, Issue:6

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Enzyme Activation; Haloperidol; Male; Metoclopramide; Rats; Sulpiride

1976
Stereoselective effects of the potentially neuroleptic rigid spiro amines.
    Nature, 1976, Oct-07, Volume: 263, Issue:5577

    Topics: Apomorphine; Binding, Competitive; Chlorpromazine; Cyclohexylamines; Dibenzocycloheptenes; Spiro Compounds; Stereoisomerism

1976
The effect of anti-parkinsonian drugs on chlorpromazine-induced depression of operant behaviour.
    Pharmacology, 1976, Volume: 14, Issue:3

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Atropine; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Phenothiazines; Rats; Trihexyphenidyl

1976
Restoration of self-stimulation inhibited by neuroleptics.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Cocaine; Dexetimide; Dopamine Antagonists; Isoquinolines; Male; Pimozide; Rats; Receptors, Dopamine; Self Stimulation; Tranquilizing Agents

1976
[Interaction between L-dopa and other drugs].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Nov-22, Volume: 31, Issue:47

    Topics: Amantadine; Anti-Arrhythmia Agents; Apomorphine; Chlorpromazine; Drug Antagonism; Drug Interactions; Drug Synergism; Humans; Levodopa; Parkinson Disease; Tranquilizing Agents

1976
Relative role of catecholamines in head-shaking of infant rats.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:1

    Topics: Animals; Animals, Newborn; Apomorphine; Behavior; Catecholamines; Chlorpromazine; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Humans; Male; Motor Activity; Phenoxybenzamine; Physostigmine; Propranolol; Rats; Stereotyped Behavior

1976
[Effects of psychotropic drugs and the roles of the noradrenergic and dopaminergic systems in the lateral hypothalamic self-stimulation behavior].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:7

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; Chlorpromazine; Dopamine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Hypothalamus; Hypothalamus, Posterior; Imipramine; Male; Methamphetamine; Norepinephrine; Phenylthiazolylthiourea; Psychotropic Drugs; Rats; Self Stimulation

1976
Screening hallucinogenic drugs: systematic study of three behavioral tests.
    Psychopharmacologia, 1975, May-28, Volume: 42, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Arousal; Behavior, Animal; Chlorpromazine; Diazepam; Drug Evaluation, Preclinical; Grooming; Hallucinogens; Head; Male; Mice; Morphine; Motor Activity; Movement Disorders; Pentobarbital; Rats; Reinforcement Schedule; Reinforcement, Psychology; Research Design

1975
Attempts to measure endogenous levels of dopa and 5-hydroxytryptophan in rat brain.
    Journal of neural transmission, 1975, Volume: 36, Issue:3-4

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Female; Hypertension; Male; Methods; Methyltyrosines; Microwaves; Norepinephrine; Pentobarbital; Rats; Serotonin; Species Specificity

1975
Inhibition of the sympathetic nervous system by 5,6-dihydroxy-2-dimethylamino tetralin (M-7), apomorphine and dopamine.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:2

    Topics: Animals; Apomorphine; Autonomic Fibers, Postganglionic; Blood Pressure; Cats; Chlorpromazine; Depression, Chemical; Dimethylamines; Dogs; Dopamine; Electric Stimulation; Emetics; Haloperidol; Naphthols; Reflex; Sciatic Nerve; Sympathetic Nervous System; Vagus Nerve

1975
Role of the strio-pallidal system and motor cortex in induced circus movements in rats and cats.
    Experimental neurology, 1975, Volume: 47, Issue:1

    Topics: Animals; Apomorphine; Brain Mapping; Cats; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Levodopa; Locomotion; Male; Mesencephalon; Motor Cortex; Movement Disorders; Neural Pathways; Rats

1975
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.
    British journal of pharmacology, 1975, Volume: 54, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clopenthixol; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Methamphetamine; Models, Biological; Oxotremorine; Parasympathomimetics; Pimozide; Rats; Scopolamine; Substantia Nigra; Thioridazine; Tranquilizing Agents

1975
Inhibition by dopamine of 3H-noradrenaline release elicited by nerve stimulation in the isolated cat's nictitating membrane.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:2

    Topics: Animals; Apomorphine; Autonomic Fibers, Postganglionic; Cats; Chlorpromazine; Cocaine; Depression, Chemical; Dopamine; Electric Stimulation; Female; In Vitro Techniques; Male; Neuromuscular Junction; Nictitating Membrane; Norepinephrine; Phenoxybenzamine; Phentolamine; Receptors, Drug; Stimulation, Chemical

1975
Effects of penfluridol and other drugs on apomorphine-induced stereotyped behavior in monkeys.
    European journal of pharmacology, 1975, Volume: 31, Issue:2

    Topics: Animals; Apomorphine; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Haloperidol; Humans; Injections, Subcutaneous; Macaca fascicularis; Male; Methyltyrosines; Nialamide; Penfluridol; Piperidines; Reserpine; Stereotyped Behavior; Time Factors

1975
Pharmacological studies of drug action on CNS, with special reference to effects of maprotiline.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:3

    Topics: Action Potentials; Amitriptyline; Animals; Anthracenes; Antiemetics; Apomorphine; Body Weight; Cats; Chlorpromazine; Crowding; Dogs; Humans; Imipramine; Male; Maprotiline; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Rats; Reflex; Reflex, Monosynaptic; Spatial Behavior; Spinal Cord; Stereotyped Behavior

1975
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine.
    Psychopharmacologia, 1975, Volume: 41, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Haloperidol; Homovanillic Acid; Humans; Loxapine; Male; Movement Disorders; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome

1975
The behavioral pharmacology of butaclamol hydrochloride (AY-23,028), a new potent neuroleptic drug.
    Psychopharmacologia, 1975, Apr-30, Volume: 42, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Catalepsy; Chlorpromazine; Dextroamphetamine; Dibenzocycloheptenes; Discrimination Learning; Dogs; Epinephrine; Fluphenazine; Humans; Male; Mice; Motor Activity; Quinolizines; Rats; Stereotyped Behavior; Tranquilizing Agents; Vomiting

1975
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors

1975
Pharmacological studies of caerulein. II. The possibility of mediation through the central nervous system.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:3

    Topics: Animals; Apomorphine; Atropine; Blood Pressure; Central Nervous System; Ceruletide; Chlorpromazine; Copper; Dogs; Female; Gallbladder; Gastrointestinal Motility; Male; Metoclopramide; Splanchnic Nerves; Sulfates; Vagotomy; Vomiting

1975
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Chlorpromazine; Clozapine; Corpus Striatum; Dextroamphetamine; Diazepam; Dopamine; Haloperidol; Humans; Hydroxydopamines; Levodopa; Male; Metoclopramide; Mice; Motor Activity; Pentobarbital; Phenoxybenzamine; Pimozide; Promethazine; Stereotyped Behavior; Tranquilizing Agents

1975
Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification.
    Movement disorders : official journal of the Movement Disorder Society, 1992, Volume: 7, Issue:2

    Topics: Aged; Apomorphine; Chlorpromazine; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Electromyography; Female; Humans; Levodopa; Lisuride; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Sulpiride

1992
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:3

    Topics: Aggression; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Behavior, Animal; Chlorpromazine; Haloperidol; Male; Mescaline; Mice; Mice, Inbred BALB C; Piperidines; Rats; Receptors, Serotonin; Receptors, sigma

1992
Prevention of neuroleptic-induced dopamine D2 receptor supersensitivity by chronic iron salt treatment.
    European journal of pharmacology, 1991, Sep-17, Volume: 202, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Chromatography, High Pressure Liquid; Dopamine; Ferrous Compounds; Free Radicals; Hemoglobins; Homovanillic Acid; In Vitro Techniques; Iron; Liver; Male; Nerve Degeneration; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone

1991
Dopaminergic unique affinity of tetrahydroberberine and l-tetrahydroberberine-d-camphor sulfonate.
    Pharmacology, 1991, Volume: 43, Issue:6

    Topics: Animals; Apomorphine; Berberine; Camphor; Chlorpromazine; Diazepam; Drug Combinations; Male; Mastication; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sleep; Tritium

1991
Chronic treatment with chlorpromazine, thioridazine or haloperidol increases striatal enkephalins and their release from rat brain.
    Psychopharmacology, 1991, Volume: 104, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Chlorpromazine; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Haloperidol; Male; Rats; Rats, Inbred Strains; Thioridazine

1991
Alterations in dopamine release from striatal slices of rats after chronic treatment with haloperidol.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains

1991
Antagonism of presynaptic dopamine receptors by phenothiazine drug metabolites.
    Life sciences, 1990, Volume: 46, Issue:6

    Topics: Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dopamine; Electric Stimulation; Fluphenazine; Male; Methotrimeprazine; Rabbits; Receptors, Dopamine

1990
Interactions of apomorphine and a novel neuroleptic dibenzodioxazocine derivative, as evidenced by changes of somato-autonomic reflexes and spontaneous sympathetic activity in cats.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:8

    Topics: Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Blood Pressure; Cats; Chlorpromazine; Dibenzoxazepines; Female; Haloperidol; In Vitro Techniques; Kidney; Male; Nictitating Membrane; Reflex; Sympathetic Nervous System

1989
The pathophysiology of tardive dyskinesia.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4 Pt 2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Fluphenazine; Guinea Pigs; Haloperidol; Humans; Receptors, Dopamine; Stereotyped Behavior; Thioridazine; Time Factors

1985
1.2-Anellated 1.4-benzodiazepine derivatives--a new class of antipsychotics.
    Pharmacopsychiatry, 1985, Volume: 18, Issue:1

    Topics: Aggression; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Apomorphine; Arousal; Behavior, Animal; Benzodiazepines; Chlorpromazine; Diazepam; Female; Haloperidol; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Rats; Rats, Inbred Strains; Sleep Stages

1985
Quantitative electrocortical changes in the rat induced by phencyclidine and other stimulants.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Dioxolanes; Electroencephalography; Isoquinolines; Isoxazoles; Male; Muscimol; Phencyclidine; Rats; Rats, Inbred Strains

1985
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra

1985
3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:2

    Topics: 4-Butyrolactone; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Buspirone; Carbazoles; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Fluphenazine; Haloperidol; Male; Molindone; Pargyline; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Regression Analysis

1986
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine

1986
Charged analogues of chlorpromazine as dopamine antagonists.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:9

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Dopamine Antagonists; Male; Mathematics; Mice; Potassium; Structure-Activity Relationship

1987
Effects of continuous administration for 12 months of amine-depleting drugs and chlorpromazine on striatal dopamine function in the rat.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Apomorphine; Body Weight; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Indoles; Kinetics; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Spiperone; Stereotyped Behavior; Thioxanthenes

1987
The dopaminergic D receptor: another example of reductive activation?
    Medical hypotheses, 1988, Volume: 26, Issue:1

    Topics: Adenylyl Cyclases; Apomorphine; Bromocriptine; Chlorpromazine; Dopamine; Enzyme Activation; Haloperidol; Receptors, Dopamine; Receptors, Dopamine D1

1988
The effects of apomorphine, d-amphetamine and chlorpromazine on the aggressiveness of isolated Aequidens pulcher (Teleostei, Cichlidae).
    Psychopharmacology, 1986, Volume: 88, Issue:1

    Topics: Aggression; Animals; Apomorphine; Chlorpromazine; Dextroamphetamine; Female; Fishes

1986
Neurobehavioural effects of ketamine.
    Indian journal of experimental biology, 1986, Volume: 24, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Hypnotics and Sedatives; Ketamine; Mice; Motor Activity; Rats; Rats, Inbred Strains; Sleep

1986
Effect of cyclic nucleotides on apomorphine stereotypy and chlorpromazine catalepsy in mice.
    Acta medica Polona, 1985, Volume: 26, Issue:3-4

    Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Male; Mice; Mice, Inbred Strains; Morphine; Nucleotides, Cyclic; Stereotyped Behavior; Structure-Activity Relationship

1985
Psychopharmacological profile of cholecystokinin using the self-stimulation and the drug discrimination paradigms.
    Annals of the New York Academy of Sciences, 1985, Volume: 448

    Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Cholecystokinin; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Inbred Strains; Self Stimulation

1985
SCH 23390 dissociated from conventional neuroleptics in apomorphine climbing and primate acute dyskinesia models.
    Life sciences, 1985, Dec-23, Volume: 37, Issue:25

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Benzimidazoles; Chlorpromazine; Chlorprothixene; Drug Synergism; Dyskinesia, Drug-Induced; Haloperidol; Male; Metoclopramide; Mice; Motor Activity; Saimiri; Stereotyped Behavior

1985
Dissociations between the effects of hallucinogens on behavior and raphe unit activity in behaving cats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Cats; Chlorpromazine; Dextroamphetamine; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Female; Hallucinogens; Haloperidol; Male; Metergoline; Mianserin; Neurons; Raphe Nuclei; Receptors, Serotonin; Serotonin Antagonists

1986
Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice.
    Life sciences, 1985, Nov-04, Volume: 37, Issue:18

    Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Domperidone; Drug Interactions; Haloperidol; Injections, Intraventricular; Mice; Spiperone; Stereotyped Behavior; Sulpiride

1985
Effects of dopamine agonists on hypothalamic defensive attack in cats.
    Physiology & behavior, 1985, Volume: 35, Issue:1

    Topics: Aggression; Agonistic Behavior; Animals; Apomorphine; Cats; Chlorpromazine; Diazepam; Dopamine; Haloperidol; Methamphetamine; Ventromedial Hypothalamic Nucleus

1985
Emetic effect of triazolopyrimidine, a pyrimidine compound, in dogs.
    Veterinary and human toxicology, 1985, Volume: 27, Issue:5

    Topics: Animals; Apomorphine; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Emetics; Female; Male; Pyrimidines; Triazoles

1985
Pharmacology of M & B 18,706, a drug which selectively reduces decerebrate rigidity.
    British journal of pharmacology, 1974, Volume: 50, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Cats; Cerebellar Ataxia; Cerebellum; Chlorpromazine; Decerebrate State; Dextroamphetamine; Diazepam; Dimethylamines; Dogs; Electromyography; Ischemia; Locomotion; Muscle Relaxants, Central; Muscle Rigidity; Phenothiazines; Rats; Reflex; Spinal Cord; Tranquilizing Agents; Valerates

1974
Some benzhydryl derivatives as central dopamine receptor stimulating agents.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Benzyl Compounds; Brain; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Haloperidol; Rats; Receptors, Drug; Reserpine; Tremor

1974
Effect of morphine and chlorpromazine on apomorphine-induced stereotyped behavior.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Drug Synergism; Humans; Male; Morphine; Rats; Receptors, Drug; Stereotyped Behavior

1974
The central nervous system pharmacology of an anti-emetic dihydroindolone derivative.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Aggression; Animals; Antiemetics; Apomorphine; Behavior, Animal; Cats; Chlorpromazine; Conditioning, Operant; Copper; Dextroamphetamine; Dioxoles; Dogs; Drug Synergism; Electroencephalography; Escape Reaction; Ethanol; Haplorhini; Humans; Indoles; Male; Mice; Motor Activity; Piperidines; Postural Balance; Rats; Seizures; Species Specificity; Stereotyped Behavior; Vomiting

1973
L-dopa hypotension in dogs: evidence for mediation through 5-HT release.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Chemistry; Carbidopa; Chlorpromazine; Depression, Chemical; Dogs; Drug Interactions; Female; Fenclonine; Haloperidol; Heart Rate; Levodopa; Male; Methysergide; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Serotonin; Time Factors; Yohimbine

1974
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus

1974
Effect of reserpine and other drugs on the monoamine metabolism with special reference to the CNS.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:3

    Topics: Animals; Apomorphine; Central Nervous System; Chlorpromazine; Dopamine; Enzyme Induction; Haloperidol; Imipramine; Lysergic Acid Diethylamide; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Serotonin; Stimulation, Chemical; Synaptic Transmission

1968
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
Action of various centrally acting agents in mice with unilateral caudate brain lesions.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Jul-15, Volume: 10, Issue:14

    Topics: Amphetamine; Animals; Apomorphine; Barbiturates; Catechols; Caudate Nucleus; Central Nervous System; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Dihydroxyphenylalanine; Haloperidol; Hydrazines; Meprobamate; Methyltyrosines; Mice; Pentobarbital; Perphenazine; Posture; Propionates; Pyrrolidines; Reserpine; Synaptic Transmission; Tetrabenazine

1971
Apomorphine and its effects on the spinal cord.
    Neuropharmacology, 1972, Volume: 11, Issue:3

    Topics: Animals; Apomorphine; Blood Pressure; Cattle; Chlorpromazine; Depression, Chemical; Dopamine; Electric Stimulation; Evoked Potentials; Female; Haloperidol; Kinetics; Male; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Propranolol; Reflex, Monosynaptic; Reserpine; Spinal Cord; Synaptic Transmission

1972
Apomorphine antagonism of the elevation of homovanillic acid induced by antipsychotic drugs.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jul-01, Volume: 11, Issue:13

    Topics: Amantadine; Animals; Apomorphine; Brain; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Haloperidol; Homovanillic Acid; Mice; Morphine; Phenylacetates; Receptors, Adrenergic; Structure-Activity Relationship; Synaptic Transmission; Thiothixene; Tranquilizing Agents; Trifluoperazine

1972
Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine.
    Brain research, 1973, Jun-15, Volume: 55, Issue:2

    Topics: Acetylcholine; Animals; Apomorphine; Basal Ganglia; Cats; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dopamine; Promethazine; Receptors, Cholinergic; Synaptic Transmission

1973
Influence of neuroleptic drugs and apomorphine on dopamine-sensitive adenylate cyclase of retina.
    Journal of neurochemistry, 1973, Volume: 21, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Cattle; Chlorpromazine; Cyclic AMP; Dopamine; Enzyme Activation; Ergotamine; Fluphenazine; Haloperidol; Phentolamine; Phosphorus Isotopes; Propranolol; Retina; Tranquilizing Agents

1973
Dopamine-induced inhibition of synaptic transmission in lumbar paravertebral ganglia of the dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:2

    Topics: Acetamides; Action Potentials; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Butyrophenones; Catecholamines; Chlorpromazine; Dogs; Dopamine; Dose-Response Relationship, Drug; Ergonovine; Ganglia, Spinal; Haloperidol; Isoproterenol; Methane; Norepinephrine; Phenoxybenzamine; Phentolamine; Pimozide; Piperidines; Synapses; Synaptic Transmission; Vasodilator Agents

1973
Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons.
    Life sciences, 1974, Aug-15, Volume: 15, Issue:4

    Topics: Action Potentials; Animals; Apomorphine; Bucladesine; Caudate Nucleus; Chlorpromazine; Cyclic AMP; Dopamine; Electric Conductivity; Male; Neurons; Rats

1974
Psychopharmacological effects of thiothixene and related compounds.
    Psychopharmacologia, 1968, Volume: 12, Issue:2

    Topics: Animals; Apomorphine; Avoidance Learning; Body Temperature; Catalepsy; Chlorpromazine; Dextroamphetamine; Discrimination, Psychological; Dogs; Drug Synergism; Ethanol; Hexobarbital; Humans; Male; Mice; Mortality; Phenothiazines; Prochlorperazine; Psychopharmacology; Rats; Reflex; Tranquilizing Agents; Tremor

1968
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzimidazoles; Blepharoptosis; Body Temperature Regulation; Cardiovascular System; Catalepsy; Cats; Chlorpromazine; Delayed-Action Preparations; Dogs; Female; Guinea Pigs; Haloperidol; Haplorhini; Histamine H1 Antagonists; Humans; In Vitro Techniques; Male; Methods; Mice; Muscle Contraction; Norepinephrine; Psychotic Disorders; Rabbits; Rats; Swine; Tranquilizing Agents; Vasoconstrictor Agents

1968
[Pharmacological studies on the effect of neuroleptics in animals after single and repeated application].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:12

    Topics: Amphetamine; Animals; Apomorphine; Body Temperature; Catalepsy; Cats; Chlorpromazine; Conditioning, Classical; Cricetinae; Female; Humans; Male; Mice; Nictitating Membrane; Phenothiazines; Rats; Thioridazine; Tremorine

1968
Induction of emesis by detergent ingredients and formulations.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:2

    Topics: Animals; Apomorphine; Chlorpromazine; Detergents; Diphosphates; Dogs; Female; Intubation, Gastrointestinal; Ipecac; Male; Phosphates; Sulfates; Sulfonic Acids; Vomiting

1969
[Neuroleptic therapy of schizophrenia from pharmacological viewpoint].
    Schweizerische medizinische Wochenschrift, 1969, Nov-15, Volume: 99, Issue:46

    Topics: Animals; Apomorphine; Arousal; Caudate Nucleus; Chlorpromazine; Chlorprothixene; Electroencephalography; Fluphenazine; Haloperidol; Humans; Methotrimeprazine; Perphenazine; Phenothiazines; Promazine; Rats; Reflex; Schizophrenia; Thioridazine; Tranquilizing Agents

1969
Actions of levodopa and dopamine in the central nervous system.
    JAMA, 1971, Dec-27, Volume: 218, Issue:13

    Topics: Animals; Apomorphine; Binding Sites; Brain; Central Nervous System; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Haplorhini; Hydrazines; Methyltyrosines; Neurotransmitter Agents; Parkinson Disease; Rabbits; Rats; Receptors, Cholinergic; Receptors, Neurotransmitter; Reserpine; Substantia Nigra; Synapses; Synaptic Transmission

1971
Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:8

    Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Cyclic AMP; Dopamine; Dopamine Antagonists; Enzyme Activation; Haloperidol; Isoproterenol; Male; Methods; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Drug

1972
Proceedings: The effects of COMT inhibitors on behavior and dopamine metabolism.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Catechol O-Methyltransferase Inhibitors; Cats; Chlorpromazine; Dopamine; Tritium; Tyrosine

1974
The effect of catechol-O-methyl transferase inhibitors on behavior and dopamine metabolism.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Alcohols; Animals; Apomorphine; Behavior, Animal; Brain; Carbon Radioisotopes; Catechol O-Methyltransferase Inhibitors; Cats; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Cycloheptanes; Dopamine; Kinetics; Pyrogallol; Quinolines; Rats; S-Adenosylmethionine; Time Factors; Tritium; Tyrosine

1974
Regulation of striatal acetylcholine concentration by dopamine receptors.
    Nature, 1974, Oct-11, Volume: 251, Issue:5475

    Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Pimozide; Rats; Receptors, Adrenergic

1974
Apomorphine and morphine stimulate prostaglandin biosynthesis.
    Nature, 1974, Nov-01, Volume: 252, Issue:5478

    Topics: Animals; Apomorphine; Aspirin; Cattle; Chlorpromazine; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Male; Mixed Function Oxygenases; Morphine; Prostaglandins; Seminal Vesicles; Sodium Salicylate; Stimulation, Chemical; Tritium

1974
Dopamine turnover in the rat corpus striatum: in vivo and in vitro studies on the action of amantadine.
    European journal of pharmacology, 1974, Volume: 25, Issue:2

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Body Temperature; Chlorpromazine; Corpus Striatum; Dopamine; Male; Rats; Time Factors; Tritium; Tyrosine

1974
Self-stimulation reward pathways: norepinephrine vs dopamine.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Depression, Chemical; Dopamine; Hydroxydopamines; Neurons; Norepinephrine; Punishment; Rats; Reward; Self Stimulation; Stereoisomerism; Stimulation, Chemical; Substantia Nigra

1974
Evidence that methadone stimulates prolactin release by dopamine receptor blockade.
    Endocrine research communications, 1974, Volume: 1, Issue:4

    Topics: Animals; Apomorphine; Chlorpromazine; Dopamine; Haloperidol; Male; Methadone; Prolactin; Rats; Receptors, Drug

1974
Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.
    Neuropharmacology, 1974, Volume: 13, Issue:10-11

    Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Catecholamines; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Humans; Locomotion; Male; Methyltyrosines; Phenobarbital; Promethazine; Rats; Reserpine; Stereotyped Behavior; Synapses; Time Factors

1974
Synthesis and preliminary pharmacology of a novel butyrophenone derivative, ID-4708.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9

    Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Butyrophenones; Catalepsy; Cats; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Electroencephalography; Epinephrine; Haloperidol; Hexobarbital; Humans; Hydrocarbons, Fluorinated; Imipramine; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Pain; Piperidines; Rats; Trifluperidol

1974
Pharmacologically induced behavioural supersensitivity to apomorphine.
    Nature: New biology, 1973, Oct-31, Volume: 245, Issue:148

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Motor Activity; Phenobarbital; Rats; Reserpine; Time Factors; Tranquilizing Agents; Tyrosine

1973
Measurement of fecal output in rats.
    The American journal of digestive diseases, 1972, Volume: 17, Issue:10

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats

1972
A model for the quantitative study of central dopaminergic and serotoninergic activity.
    European journal of pharmacology, 1972, Volume: 18, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Electromyography; Haloperidol; Iproniazid; Male; Methyltyrosines; Methysergide; Models, Biological; Muscle Contraction; Myoclonus; Parasympatholytics; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Stereotaxic Techniques; Substantia Nigra; Thalamus

1972
Effects of morphine on striatal dopamine metabolism: possible mechanism of its opposite effect on locomotor activity in rats and mice.
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Catechols; Caudate Nucleus; Chlorpromazine; Clonidine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Fluorometry; Homovanillic Acid; Humans; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Rats; Serine; Species Specificity; Stereotaxic Techniques; Thiocarbamates

1974
An experimental model of tardive dyskinesia.
    Journal of neural transmission, 1972, Volume: 33, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Movement Disorders; Stereotyped Behavior

1972
Effects of apomorphine and its interaction with other drugs in the domestic fowl.
    European journal of pharmacology, 1973, Volume: 23, Issue:1

    Topics: Age Factors; Aggression; Animals; Animals, Newborn; Apomorphine; Atropine; Behavior, Animal; Chickens; Chlorpromazine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Electrodes, Implanted; Electromyography; Humans; Pentobarbital; Physostigmine; Reflex; Reserpine; Scopolamine; Stereotyped Behavior; Vomiting

1973
Effect of apomorphine on growth hormone, prolactin, luteinizing hormone and follicle-stimulating hormone levels in human serum.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:5

    Topics: Adult; Apomorphine; Chlorpromazine; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Growth Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Prolactin; Time Factors

1973
Amphetamine- and apomorphine-induced alteration of the behavior of rats submitted to a competitive situation in a straight runway.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Competitive Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Pimozide; Rats; Time Factors

1973
Inhibition of the apomorphine gnawing compulsion by amantadine.
    Experientia, 1973, Volume: 29, Issue:12

    Topics: Amantadine; Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Synergism; Male; Metoclopramide; Rats

1973
Antagonism of the effects of chlorpromazine and morphine on dopamine metabolism by GABA.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1

    Topics: Acetates; Aminobutyrates; Animals; Apomorphine; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxylamines; Male; Methyltyrosines; Morphine; Rats

1974
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase

1974
Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Brain Stem; Carbidopa; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dihydroxyphenylalanine; Dioxoles; Dopamine; Drug Synergism; Haloperidol; Hippocampus; Hypothalamus; Male; Pimozide; Piperazines; Pyrimidines; Rats; Receptors, Drug; Thalamus; Time Factors

1974
Dopaminergic nature of apomorphine-induced pecking in pigeons.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Animals; Apomorphine; Aporphines; Behavior, Animal; Chlorpromazine; Columbidae; Dihydroxyphenylalanine; Dioxoles; Dopamine; Haloperidol; Imipramine; Methyltyrosines; Nicotine; Oxotremorine; Phentolamine; Physostigmine; Pilocarpine; Propranolol; Receptors, Drug; Reserpine; Serotonin; Time Factors

1974
Effect of piribedil and one of its metabolites on the concentration of homovanillic acid in the rat brain.
    European journal of pharmacology, 1974, Volume: 27, Issue:2

    Topics: Animals; Apomorphine; Brain; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dioxoles; Dopamine; Dose-Response Relationship, Drug; Female; Fenfluramine; Haloperidol; Homovanillic Acid; Phenylacetates; Piperazines; Pyrimidines; Rats; Time Factors

1974
The conformation of neuroleptic drugs.
    Molecular pharmacology, 1974, Volume: 10, Issue:3

    Topics: Amines; Apomorphine; Benperidol; Butyrophenones; Chlorpromazine; Haloperidol; Hydrogen; Models, Structural; Molecular Conformation; Phenothiazines; Piperidines; Reserpine; Structure-Activity Relationship; Thiothixene; Thioxanthenes; Tranquilizing Agents; X-Ray Diffraction

1974
Apomorphine induced biting and fighting behaviour in reserpinized rats and an approach to the mechanism of action.
    Life sciences, 1974, Feb-16, Volume: 14, Issue:4

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Chlorpromazine; Clonidine; Dihydroxyphenylalanine; Dopamine; Humans; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Pimozide; Rats; Receptors, Drug; Reserpine; Thiocarbamates; Time Factors

1974
Pharmacological effects of 1,3-dimethyl-5-aminoadamantane, a new adamantane derivative.
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Amantadine; Animals; Apomorphine; Blood Pressure; Body Temperature; Brain Chemistry; Catalepsy; Chlorpromazine; Dextroamphetamine; Disulfides; Dopamine; Female; Fluphenazine; Haloperidol; Humans; Imidazoles; Male; Methyltyrosines; Motor Activity; Norepinephrine; Oxotremorine; Parasympatholytics; Rats; Reflex; Reserpine; Spiro Compounds; Stereotyped Behavior

1974
Inhibition of rat prolactin release by apomorphine in vivo and in vitro.
    Endocrinology, 1974, Volume: 95, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Estrus; Female; In Vitro Techniques; Lactation; Pimozide; Pituitary Gland; Pregnancy; Prolactin; Rats; Receptors, Drug

1974
[Behavioral effects of lithium chloride].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2

    Topics: Aggression; Analysis of Variance; Anesthesia; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Catalepsy; Chlorpromazine; Drug Synergism; Electroshock; Emotions; Escape Reaction; Ethanol; Exploratory Behavior; Humans; Lithium; Locomotion; Male; Mescaline; Methamphetamine; Mice; Rats; Seizures; Sleep; Thiopental; Vocalization, Animal

1974
Biochemical and behavioral antagonism between fenfluramine and apomorphine in rats.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Female; Fenfluramine; Homovanillic Acid; Humans; Rats; Stereotyped Behavior; Time Factors

1974
Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat.
    Brain research, 1969, Volume: 14, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Dopamine; Female; Fluorescence; Functional Laterality; Histocytochemistry; Injections, Spinal; Male; Motor Activity; Nialamide; Norepinephrine; Posture; Rats; Reserpine; Stereotaxic Techniques; Stimulation, Chemical; Thalamus

1969
Psychopharmacological profile of molindone.
    Nature, 1967, Nov-11, Volume: 216, Issue:5115

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Dihydroxyphenylalanine; Dogs; Female; Haplorhini; Indoles; Locomotion; Male; Mice; Morpholines; Rats; Tetrabenazine

1967
[Pharmacological studies of oxazolazepam, a new psychotropic agent. I. Actions on the central nervous system, especially on the behavioral aspect].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Volume: 66, Issue:1

    Topics: Adaptation, Biological; Analgesics; Anesthesia; Animals; Anticonvulsants; Apomorphine; Avoidance Learning; Azepines; Behavior, Animal; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Cricetinae; Diazepam; Dogs; Drug Synergism; Drug Tolerance; Electric Stimulation; Female; Guinea Pigs; Haplorhini; Male; Mice; Morphine; Oxazoles; Rats; Seizures; Thiopental; Tranquilizing Agents; Tremorine

1970
The neuroleptics. 5. Animal behavior.
    Modern problems of pharmacopsychiatry, 1970, Volume: 5

    Topics: Amphetamine; Animals; Apomorphine; Arousal; Avoidance Learning; Behavior, Animal; Brain; Central Nervous System; Cerebral Ventricles; Chlorpromazine; Conditioning, Classical; Conditioning, Operant; Conflict, Psychological; Drive; Electric Stimulation; Electrophysiology; Habits; Haplorhini; Humans; Rats; Tranquilizing Agents

1970
Apomorphine-induced hypothermia in mice; a possible dopaminergic effect.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 198, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Body Temperature; Chlorpromazine; Depression, Chemical; Dopamine; Drug Antagonism; Fluorine; Haloperidol; Injections, Intraperitoneal; Male; Methamphetamine; Mice; Mice, Inbred Strains; Phentolamine; Receptors, Adrenergic; Spiro Compounds; Thioridazine

1972
Analogs of phenothiazines. 4. Effect of structure upon neuropharmacological activity of some chlorpromazine analogs of the diphenylmethane type.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:6

    Topics: Aggression; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Benzyl Compounds; Blepharoptosis; Chlorpromazine; Depression, Chemical; Dogs; Drug Antagonism; Humans; Male; Mice; Motor Activity; Phenothiazines; Rats; Reserpine; Structure-Activity Relationship; Xanthenes

1972
Morphine catalepsy in the rat: relation to striatal dopamine metabolism.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains

1972
Pharmacological properties of a new potential neuroleptic drug oxyprothepin. IV. Antiadrenergic action and influence on brain monoamines.
    Activitas nervosa superior, 1971, Volume: 13, Issue:3

    Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chlorpromazine; Dibenzothiepins; Dogs; Dopamine; Drug Interactions; Epinephrine; Feeding Behavior; Locomotion; Mastication; Mice; Norepinephrine; Phenmetrazine; Physostigmine; Piperazines; Rabbits; Rats; Serotonin; Tranquilizing Agents; Vomiting

1971
Blockade of depressor response of dopamine.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Animals; Apomorphine; Blood Pressure; Cats; Chlorpromazine; Codeine; Dopamine; Female; Male; Meperidine; Morphine; Phenothiazines; Phenoxybenzamine; Yohimbine

1969
Mode of action of chlorpromazine on unit discharges from nuclear structures in the brainstem of cats.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:3

    Topics: Animals; Apomorphine; Brain Stem; Cats; Chlorpromazine; Drug Antagonism; Electrophysiology; Female; Injections, Intravenous; Male; Medulla Oblongata; Pons; Trigeminal Nerve; Vestibular Nuclei

1970
Biogenic amines, cold-adaptation and halothane shivering in mice.
    Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2

    Topics: Adaptation, Physiological; Amino Acids; Anesthesia, Inhalation; Animals; Apomorphine; Catecholamines; Chlorpromazine; Cold Temperature; Dihydroxyphenylalanine; Halothane; Male; Mice; Phenelzine; Phenoxybenzamine; Propranolol; Shivering; Sleep; Sympatholytics; Sympathomimetics; Tetrabenazine; Time Factors

1969
Neuropharmacology of apomorphine.
    Activitas nervosa superior, 1970, Volume: 12, Issue:3

    Topics: Amitriptyline; Animals; Apomorphine; Arousal; Behavior, Animal; Benactyzine; Chlorpromazine; Electroencephalography; Imipramine; Nervous System; Perphenazine; Rats

1970
New method for assaying antiapomorphine activity in pigeons.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:12

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine

1970
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:7

    Topics: Acepromazine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benperidol; Chlorpromazine; Chlorprothixene; Fluphenazine; Haloperidol; Male; Mastication; Methods; Motor Activity; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rats; Thiazines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1967
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
    Psychopharmacologia, 1968, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline

1968
[Central effects of some adreno- and-or sympatholytic substances. 3. Ptosis, catalepsy, antagonism with respect to apomorphine and amphetamine].
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 171, Issue:1

    Topics: Animals; Apomorphine; Blepharoptosis; Bretylium Compounds; Catalepsy; Central Nervous System; Chlorpromazine; Dextroamphetamine; Dibenzylchlorethamine; Ergotamine; Eyelids; Guanethidine; Humans; Methyldopa; Mice; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Tranquilizing Agents; Yohimbine

1968
Anti-emetic activity of N-[4-(2-methylaminoethoxy)benzyl]-3,4-diethoxybenzamide hydrochloride.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 174, Issue:2

    Topics: Amides; Animals; Antiemetics; Apomorphine; Benzamides; Cardiovascular System; Cats; Chlorpromazine; Copper; Dogs; Guinea Pigs; Rats; Sulfates; Vomiting

1968
[Modification of central mechanisms of action by anticholinergics].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine

1969
Blockade of apomorphine pecking with phenothiazines.
    Psychopharmacologia, 1965, Jul-28, Volume: 8, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Birds; Chemistry, Organic; Chemistry, Pharmaceutical; Chlorpromazine; Organic Chemistry Phenomena; Phenothiazines; Piperazines; Piperidines; Psychopharmacology; Pyrrolidines; Tranquilizing Agents

1965
Influence of antiparkinson drugs and amphetamine on some pharmacological effects of phenothiazine derivatives used as neuroleptics.
    Psychopharmacologia, 1964, Sep-11, Volume: 6, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Body Temperature; Catalepsy; Chlorpromazine; Dextroamphetamine; Dogs; Humans; Mastication; Mice; Movement; Pentobarbital; Perphenazine; Rats; Scopolamine; Trifluoperazine; Trihexyphenidyl; Vomiting

1964
The pharmacological properties of a potent neurotropic compound from the dibenzothiazepine group.
    International journal of neuropharmacology, 1965, Volume: 4, Issue:6

    Topics: Acetylcholine; Animals; Apomorphine; Behavior, Animal; Blood Circulation; Blood Pressure; Body Temperature; Catalepsy; Cats; Chlorpromazine; Electroencephalography; Electromyography; Electroshock; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Locomotion; Rabbits; Rats; Serotonin; Tranquilizing Agents

1965
Observations on the pharmacology of diphenidol, a potent antiemetic.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:2

    Topics: Animals; Antiemetics; Apomorphine; Asthenia; Blood Pressure; Chlorpromazine; Dogs; Ethers; Gastrointestinal Motility; Guinea Pigs; Pupil; Rats; Vomiting

1966
Antiamphetamine effects following inhibition of tyrosine hydroxylase.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 151, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Chlorpromazine; Dihydroxyphenylalanine; Enzymes; In Vitro Techniques; Male; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Phenobarbital; Rats; Tryptamines; Tyrosine

1966
[Mechanism of the genesis of emesis in the period of the primary reaction to irradiation].
    Meditsinskaia radiologiia, 1966, Volume: 11, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Copper; Dogs; Radiation Injuries, Experimental; Sulfates; Vagus Nerve; Vomiting

1966
Adrenergic effect of chronic administration of neuroleptics.
    Nature, 1967, Jun-17, Volume: 214, Issue:5094

    Topics: Amphetamine; Animals; Apomorphine; Chlorpromazine; Feedback; Haloperidol; Perphenazine; Rats; Sympathetic Nervous System; Tetrabenazine; Tranquilizing Agents; Trifluoperazine

1967
The effect of stimulation of pre- and postsynaptic dopamine receptors on the endogenous inhibitor of cAMP-dependent protein kinase.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 272, Issue:2

    Topics: Aminophylline; Animals; Apomorphine; Carrier Proteins; Chlorpromazine; Electric Stimulation; Haloperidol; Intracellular Signaling Peptides and Proteins; Male; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Time Factors

1984
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
    Psychopharmacology, 1980, Volume: 69, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Mouth Diseases; Movement Disorders; Occipital Lobe; Rats; Substance Withdrawal Syndrome

1980
Behavioural effects of chronic treatment with apomorphine in combination with neuroleptic drugs.
    Journal of neuroscience research, 1980, Volume: 5, Issue:4

    Topics: Aggression; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Drug Therapy, Combination; Humans; Male; Rats; Stereotyped Behavior; Thioridazine

1980
beta-Phenylethylamine reversal of chlorpromazine-induced activation of striatal tyrosine hydroxylase and catalepsy.
    Brain research, 1981, May-04, Volume: 211, Issue:2

    Topics: Animals; Apomorphine; Catalepsy; Caudate Nucleus; Chlorpromazine; Dextroamphetamine; Humans; Male; Phenethylamines; Rats; Tyrosine 3-Monooxygenase

1981
Effects of drugs interfering with dopamine and noradrenaline biosynthesis on the endogenous 3,4-dihydroxyphenylalanine levels in rat brain.
    Journal of neurochemistry, 1982, Volume: 39, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Brain; Chlorpromazine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution; Tyrosine 3-Monooxygenase

1982
A study on the pharmacological and biochemical profile of clocapramine.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Apomorphine; Benzodiazepines; Body Temperature Regulation; Chlorpromazine; Dibenzazepines; Drug Interactions; Imipramine; Male; Methamphetamine; Motor Activity; Muridae; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Self Stimulation; Sulpiride; Tranquilizing Agents

1982
Animal models of tardive dyskinesias.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Disease Models, Animal; Dyskinesia, Drug-Induced; Epidemiologic Methods; Guinea Pigs; Haloperidol; Humans; Time Factors

1983
Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity.
    Neuroscience letters, 1984, Jun-15, Volume: 47, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Male; Peptides; Pimozide; Rats; Rats, Inbred Strains; Time Factors

1984
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding, Competitive; Brain Chemistry; Catalepsy; Chlorpromazine; Dogs; Female; Haloperidol; Histocytochemistry; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Spiperone; Sulpiride; Thioridazine; Vomiting

1984
Prolactin-releasing effect of zetidoline, a new neuroleptic agent, in the rat.
    Pharmacological research communications, 1984, Volume: 16, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Estrus; Female; Haloperidol; Imidazoles; Levodopa; Male; Pregnancy; Prolactin; Rats; Rats, Inbred Strains

1984
Effects of apomorphine and methamphetamine on a quickly-learned conditioned-suppression response in rats.
    Neuropharmacology, 1983, Volume: 22, Issue:7

    Topics: alpha-Methyltyrosine; Animals; Apomorphine; Atropine; Chlorpromazine; Conditioning, Operant; Emotions; Fenclonine; Haloperidol; Male; Methamphetamine; Methyltyrosines; Rats; Rats, Inbred Strains

1983
Effects of diazepam, meprobamate, chlorpromazine and apomorphine on a quickly learned conditioned suppression in mice.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:8

    Topics: Animals; Apomorphine; Chlorpromazine; Conditioning, Psychological; Diazepam; Dose-Response Relationship, Drug; Male; Meprobamate; Mice; Motor Activity

1983
Potentiation of the psychotropic effect of chlorpromazine by metoclopramide.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Drug Synergism; Male; Metoclopramide; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains

1983
LSD-potentiated apomorphine hypermotility: a model for differentiating antipsychotic drugs.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1

    Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Disease Models, Animal; Drug Antagonism; Haloperidol; Humans; Hyperkinesis; Lysergic Acid Diethylamide; Male; Motor Activity; Rats; Rats, Inbred Strains; Sulpiride

1983
Effect of intracerebroventricular administration of chlorpromazine on the serum level of free fatty acids in rats.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:4

    Topics: Animals; Apomorphine; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Haloperidol; Hydroxydopamines; Injections, Intraventricular; Male; Oxidopamine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical

1982
Effects of glycine, chlorpromazine and apomorphine on brain monoamines and free amino acids in rats.
    Pharmacological research communications, 1983, Volume: 15, Issue:1

    Topics: Amino Acids; Animals; Apomorphine; Binding, Competitive; Biogenic Amines; Brain; Chlorpromazine; Dopamine; Glycine; Levodopa; Rats; Rats, Inbred Strains; Time Factors

1983
Pharmacological properties of a potent neuroleptic drug octoclothepin.
    Acta biologica et medica Germanica, 1980, Volume: 39, Issue:6

    Topics: Amphetamines; Animals; Apomorphine; Autonomic Nervous System; Central Nervous System; Chlorpromazine; Depression, Chemical; Dibenzothiepins; Drug Interactions; Locomotion; Male; Mice; Motor Activity; Perphenazine; Rats

1980
[Effect of the stimulators and inhibitors of the central dopaminergic structures on the kininogen level and kallikrein activity in the rat plasma].
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1980, Volume: 35

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Chlorpromazine; Haloperidol; Kallikreins; Kininogens; Male; Rats; Receptors, Dopamine; Reserpine

1980
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine

1982
Reversal of respiratory responses to dopamine after dopamine antagonists.
    Respiration physiology, 1982, Volume: 47, Issue:2

    Topics: Animals; Apomorphine; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Female; Haloperidol; Male; Nitrogen; Oxygen; Perphenazine; Respiration; Spiperone

1982
Effects of haloperidol and apomorphine on catecholamine metabolism in brain slices. Reserpine-like effects of haloperidol.
    Biochemical pharmacology, 1982, Oct-15, Volume: 31, Issue:20

    Topics: Animals; Apomorphine; Brain Chemistry; Catecholamines; Chlorpromazine; Dopamine; Fluphenazine; Haloperidol; Male; Mice; Nerve Tissue Proteins; Reserpine

1982
Correlation between daily dosage of chlorpromazine and subsequent supersensitivity.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Membranes; Stereotyped Behavior

1980
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
    Journal of neural transmission, 1981, Volume: 52, Issue:3

    Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Haloperidol; Humans; Hyperkinesis; Kinetics; Organ Specificity; Rats; Receptors, Dopamine; Receptors, Drug; Spiperone; Stereotyped Behavior; Sulpiride; Thioridazine

1981
[Studies on the situational factors affecting the effect of psychotropic drugs. II. Circadian fluctuation of sedative and anti-apomorphine effects of chlorpromazine (author's transl)].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1981, Volume: 83, Issue:4

    Topics: Animals; Apomorphine; Brain; Chlorpromazine; Circadian Rhythm; Hypnotics and Sedatives; Male; Rats

1981
Effects of L-dopa, chlorpromazine and apomorphine on brain monoamines and free amino acids in rats.
    Pharmacological research communications, 1981, Volume: 13, Issue:8

    Topics: Amino Acids; Animals; Apomorphine; Biogenic Amines; Brain Chemistry; Chlorpromazine; Levodopa; Rats; Rats, Inbred Strains

1981
Effects of atypical antipsychotic agents on social behavior in rodents.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior

1993
Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications.
    European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3

    Topics: Animals; Apomorphine; Butyrophenones; Cell Line; Chlorpromazine; Clozapine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Raclopride; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Salicylamides; Trifluoperazine

1993
Interaction of AZA analogs of chlorpromazine with the dopamine D2 receptor.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Aza Compounds; Binding, Competitive; Chlorpromazine; Corpus Striatum; In Vitro Techniques; Male; Mice; Potassium; Quaternary Ammonium Compounds; Receptors, Dopamine D2; Spiperone

1993
Serotonin2 (5-HT2) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) inhibits chlorpromazine- and haloperidol-induced hypothermia in mice.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:11

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amphetamines; Animals; Apomorphine; Behavior, Animal; Body Temperature; Chlorpromazine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Hypothermia, Induced; Male; Mice; Mice, Inbred ICR; Phenylephrine; Receptors, Dopamine D2; Serotonin Receptor Agonists

1995
Effects of oral lithium on the action of various C.N.S. active drugs.
    Indian journal of physiology and pharmacology, 1996, Volume: 40, Issue:3

    Topics: Administration, Oral; Animals; Apomorphine; Chlorpromazine; Columbidae; Drug Synergism; Female; Haloperidol; Lithium; Male; Psychotropic Drugs; Rabbits; Rats

1996
Effects of dopaminergic drugs on locomotor activity in teleost fish of the genus Oreochromis (Cichlidae): involvement of the telencephalon.
    Physiology & behavior, 1998, Jun-01, Volume: 64, Issue:3

    Topics: Animals; Apomorphine; Chlorpromazine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Metoclopramide; Motor Activity; Nasal Mucosa; Telencephalon; Tilapia

1998
Effects of dopamine and dopamine-active compounds on oxytocin and vasopressin production in rat neurohypophyseal tissue cultures.
    Regulatory peptides, 2001, Apr-02, Volume: 98, Issue:1-2

    Topics: Animals; Apomorphine; Butaclamol; Chlorpromazine; Culture Techniques; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Haloperidol; Male; Neuroglia; Oxytocin; Pituitary Gland; Rats; Rats, Wistar; Sulpiride; Vasopressins

2001
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine

2001
The anti-emetic activity of 10-(gamma-dimethylaminopropyl)-2-chlorophenothiazine (chlorpromazine) in dog and cat.
    The Journal of pharmacology and experimental therapeutics, 1954, Volume: 110, Issue:1

    Topics: Animals; Antiemetics; Apomorphine; Autonomic Agents; Autonomic Nervous System; Cats; Chlorpromazine; Dogs; Gamma Rays; Vomiting

1954
Influence of chlorpromazine and promethazine on vomiting induced with apomorphine in man.
    Lancet (London, England), 1954, Sep-18, Volume: 267, Issue:6838

    Topics: Apomorphine; Autonomic Agents; Chlorpromazine; Histamine H1 Antagonists; Humans; Male; Promethazine; Vomiting

1954
[Effects of chlorpromazine on the vomiting mechanism in pigeons].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1956, Volume: 228, Issue:1-2

    Topics: Animals; Apomorphine; Chlorpromazine; Columbidae; Digitalis; Digitalis Glycosides; Vomiting

1956
Studies on the antiemetic efficacy of chlorpromazine and promethazine against apomorphine induced emesis in dogs.
    Indian journal of medical sciences, 1957, Volume: 11, Issue:2

    Topics: Animals; Antiemetics; Apomorphine; Chlorpromazine; Dogs; Histamine H1 Antagonists; Promethazine; Vomiting

1957
[Chlorpromazine (largactil) facilitates vomiting induced by apomorphine in cats].
    Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica, 1957, Volume: 4

    Topics: Animals; Apomorphine; Cats; Chlorpromazine; Vomiting

1957
[THE INFLUENCE OF CHLORPROMAZINE AND RESERPINE ON THE EMETIC EFFECTS OF CERTAIN DRUGS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1962, Volume: 9

    Topics: Alkaloids; Ammonium Compounds; Antimony; Apomorphine; Chlorpromazine; Dogs; Emetics; Gluconates; Pharmacology; Quaternary Ammonium Compounds; Research; Reserpine

1962
[EMETIC ACTION OF ACETYLSALICYLIC ACID].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-04, Volume: 257

    Topics: Animals; Apomorphine; Aspirin; Cats; Chlorpromazine; Copper; Dogs; Emetics; Pharmacology; Research; Sulfates; Vomiting; Yohimbine

1963
ANTI-EMETIC ACTIVITY OF PHENOTHIAZINES IN RELATION TO THEIR CHEMICAL STRUCTURE.
    British journal of pharmacology and chemotherapy, 1963, Volume: 21

    Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Chemistry, Pharmaceutical; Chlorpromazine; Dogs; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Research; Thioridazine; Tranquilizing Agents; Trifluoperazine

1963
[EFFECT OF APOMORPHINE, ERGOTAMINE, RESERPINE AND YOHIMBINE ON THE BLINKING REFLEX OF THE RABBIT].
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 10

    Topics: Animals; Apomorphine; Blinking; Chlorpromazine; Ergotamine; Eyelids; Light; Methamphetamine; Pharmacology; Pupil; Rabbits; Reflex; Research; Reserpine; Yohimbine

1964
[METOCLOPRAMIDE AND ITS HOMOLOGUES. INTRODUCTION TO THEIR BIOLOGICAL STUDY].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Apr-27, Volume: 258

    Topics: Animals; Antiemetics; Apomorphine; Central Nervous System; Chlorpromazine; Dogs; Lagomorpha; Metoclopramide; Mice; Pharmacology; Rabbits; Rats; Research; Toxicology

1964
[ANTIEMETIC ACTION OF METOCLOPRAMIDE WITH RESPECT TO APOMORPHINE AND HYDERGINE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Antiemetics; Apomorphine; Benzamides; Cardiovascular Agents; Chlorpromazine; Dihydroergotoxine; Diphenhydramine; Dogs; Ergoloid Mesylates; Ergot Alkaloids; Metoclopramide; Oxytocics; Pharmacology; Prochlorperazine; Research; Toxicology

1964
ALCOHOLISM.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Alcohol Deterrents; Alcoholism; Apomorphine; Chlorpromazine; Diet; Diet Therapy; Disulfiram; Humans; Promazine; Psychoses, Alcoholic; Psychotic Disorders; Vitamin A; Vitamin K; Vitamins

1964
Serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of Lymnaea stagnalis L.
    Acta biologica Hungarica, 2004, Volume: 55, Issue:1-4

    Topics: Amphetamines; Animals; Apomorphine; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Embryo, Nonmammalian; Embryonic Development; Fenclonine; Hydrazines; Locomotion; Lymnaea; Lysergic Acid Diethylamide; Methysergide; N,N-Dimethyltryptamine; Serotonin; Serotonin Receptor Agonists; Tryptamines; Tryptophan; Tyramine; Tyrosine

2004
Role of glutamate and dopamine receptors in the psychopharmacological profile of the indole alkaloid psychollatine.
    Journal of natural products, 2006, Volume: 69, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brazil; Chlorpromazine; Diazepam; Dizocilpine Maleate; Glycosides; Indole Alkaloids; Male; Memory; Mice; Models, Biological; Molecular Structure; Plants, Medicinal; Psychopharmacology; Psychotria; Receptors, Dopamine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Receptor Agonists

2006
The Antipsychotic Effects of Omega-3 Fatty Acids in Rats.
    The American journal of the medical sciences, 2015, Volume: 350, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Docosahexaenoic Acids; Dopamine Agonists; Eicosapentaenoic Acid; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Stereotyped Behavior

2015
Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis.
    BMC complementary and alternative medicine, 2017, Aug-07, Volume: 17, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Asteraceae; Behavior, Animal; Catalepsy; Chlorpromazine; Disease Models, Animal; Haloperidol; Herb-Drug Interactions; Hypnotics and Sedatives; Mice, Inbred BALB C; Mice, Inbred ICR; Motor Activity; Phytotherapy; Plant Extracts; Psychotic Disorders

2017