chlorpromazine has been researched along with antipyrine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (41.18) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 9 (26.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Goetz, GH; Philippe, L; Shapiro, MJ | 1 |
| Lader, MH | 1 |
| Curry, S; Lader, M; Loga, S | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
| Monro, P | 1 |
| Graeme, ML; Sigg, EB; Simke, J | 1 |
| Ballinger, BR; O'Malley, K; Stevenson, IH; Turnbull, MJ | 1 |
| Maickel, RP | 1 |
| Murai, S; Oizumi, Y; Ozawa, H; Seto, S | 1 |
| Akhmedov, KM; Gadzhiev, MA; Kuliev, GD; Volkova, GG | 1 |
| Houser, J; Jaramillo, J; Kruger, S; Mattes, LM; Spoto, E | 1 |
| Luczynska, C; Wilson, K | 1 |
| Keller, F; Waser, PG | 1 |
| Frewin, DB; Harman, AW; Priestly, BG | 1 |
| Fenyves, D; Gariépy, L; Villeneuve, JP | 1 |
| CHANG, TM; WU, YP | 1 |
3 review(s) available for chlorpromazine and antipyrine
| Article | Year |
|---|---|
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
Techniques for the microassay of drugs in biological materials.
Topics: Animals; Antigen-Antibody Reactions; Antipyrine; Body Fluids; Catechol O-Methyltransferase; Chlorpromazine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Haptens; Humans; Immunoassay; Indicator Dilution Techniques; Isotopes; Methyltransferases; Microchemistry; Pharmaceutical Preparations; Phenylethanolamine N-Methyltransferase; Proteins; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Tissue Extracts; Tryptamines | 1973 |
The clinical significance of the effects of cigarette smoking on drug disposition.
Topics: Acetaminophen; Antipyrine; Benzodiazepines; Chlorpromazine; Clomipramine; Codeine; Humans; Pharmaceutical Preparations; Phenacetin; Propranolol; Smoking; Theophylline; Warfarin | 1983 |
1 trial(s) available for chlorpromazine and antipyrine
| Article | Year |
|---|---|
Interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man.
Topics: Adult; Antipyrine; Chlorpromazine; Clinical Trials as Topic; Drug Interactions; Female; Half-Life; Humans; Male; Orphenadrine; Phenobarbital; Psychotic Disorders | 1975 |
30 other study(ies) available for chlorpromazine and antipyrine
| Article | Year |
|---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides.
Topics: | 2014 |
[Rational utilization of the major tranquilizers].
Topics: Adult; Antipsychotic Agents; Antipyrine; Chlorpromazine; Drug Interactions; Drug Therapy, Combination; Drug Utilization; Electroencephalography; Half-Life; Humans; Liver; Male; Orphenadrine; Phenobarbital; Psychotic Disorders; Theta Rhythm; Time Factors | 1975 |
Iatrogenic encephalopathy.
Topics: Adult; Antipyrine; Brain Diseases; Chloral Hydrate; Chlorine; Chlorpromazine; Dermatitis, Exfoliative; Drug Hypersensitivity; Female; Humans; Hypnotics and Sedatives; Phosphoric Acids | 1970 |
Bradykinin induced bronchoconstriction in guinea pigs and its modification by various agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Bradykinin; Bronchi; Chlorpromazine; Drug Antagonism; Drug Synergism; Ethanolamines; Female; Guinea Pigs; Histamine; Indomethacin; Male; Methysergide; Oxyphenbutazone; Phenacetin; Phenoxybenzamine; Phenylbutazone; Sulfinpyrazone; Tripelennamine | 1967 |
The effect of chlorpromazine on drug metabolism.
Topics: Adult; Aged; Animals; Antipyrine; Barbiturates; Biotransformation; Chlorpromazine; Enzyme Induction; Half-Life; Humans; Liver; Middle Aged; Rats; Schizophrenia | 1972 |
[Pharmacological studies of troponoids. I. Hypothermic, analgesic and anti-inflammatory actions of troponoids].
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Body Temperature; Capillary Permeability; Chlorpromazine; Cycloheptanes; Erythema; Hexobarbital; Ketones; Male; Mice; Motor Activity; Pentylenetetrazole; Rats; Salicylates; Sleep; Strychnine | 1971 |
[Potentiated analgesic anesthesia].
Topics: Adjuvants, Anesthesia; Anesthesia, General; Animals; Antipyrine; Buffaloes; Cattle; Chlorpromazine; Drug Synergism; Goats; Sheep | 1969 |
The time course of distribution of antipyrine in dogs and its modification by drugs.
Topics: Animals; Antipyrine; Atropine; Blood; Blood Pressure; Cerebrospinal Fluid; Chlorpromazine; Cholecystectomy; Common Bile Duct; Dogs; Gastrectomy; In Vitro Techniques; Injections, Intravenous; Meningitis; Nephrectomy; Phentolamine; Portacaval Shunt, Surgical; Reserpine; Splenectomy; Thioridazine | 1965 |
Brain pharmacokinetics of centrally acting drugs, a quantitative autoradiographic study.
Topics: Animals; Antipyrine; Autoradiography; Brain; Cerebrovascular Circulation; Chlorpromazine; Diazepam; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains | 1984 |
Comparative enzyme-inducing effects of chlorpromazine and fluphenazine therapies in psychotic patients.
Topics: Adult; Aged; Antipyrine; Chlorpromazine; Enzyme Induction; Female; Fluphenazine; Half-Life; Humans; Liver; Male; Middle Aged; Psychotic Disorders | 1980 |
Clearance by the liver in cirrhosis. I. Relationship between propranolol metabolism in vitro and its extraction by the perfused liver in the rat.
Topics: Animals; Antipyrine; Carbon Tetrachloride; Chlorpromazine; In Vitro Techniques; Liver; Liver Circulation; Liver Cirrhosis, Experimental; Male; Perfusion; Propranolol; Rats; Rats, Sprague-Dawley | 1993 |
[SOME PHARMACOLOGICAL PROPERTIES OF ACEPROMAZINE: ITS POTENTIATING ACTION AND ITS EFFECT ON THE RELEASE OF THE TRANSMITTER FROM THE POST-GANGLIONIC SYMPATHETIC NERVE FIBRES].
Topics: Acepromazine; Analgesia; Animals; Antipyrine; Blood Pressure; Cats; Chloral Hydrate; Chlorpromazine; Cornea; Epinephrine; Ileum; Morphine; Muscle, Smooth; Nerve Endings; Nerve Fibers; Nictitating Membrane; Norepinephrine; Peripheral Nerves; Pharmacology; Procaine; Research; Sympathetic Nervous System; Vasomotor System | 1964 |