chlorpromazine and amiloride

chlorpromazine has been researched along with amiloride in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's1 (3.70)18.2507
2000's9 (33.33)29.6817
2010's12 (44.44)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Balkovetz, DF; Ganapathy, V; Hanano, M; Iwatsubo, T; Leibach, FH; Miyamoto, Y1
Hashimoto, T; Kaguchi, Y; Kimura, M; Kuriyama, S; Miyahara, T; Nakamura, K; Tamai, K; Tamura, H1
Hanano, M; Iga, T; Iwatsubo, T; Miyamoto, Y; Sugiyama, Y; Yuasa, H1
Dascalu, A; Korenstein, R; Nevo, Z; Oron, Y1
Honoré, E; Lazdunski, M; Lesage, F; Maingret, F; Patel, AJ1
Drumm, K; Gassner, B; Gekle, M; Silbernagl, S1
Carlsson, MC; Carlsson, S; Leffler, H1
Chandran, B; Raghu, H; Sadagopan, S; Sharma-Walia, N; Veettil, MV1
Ma, DX; Qi, XR1
Chao, TY; Raines, RT1
Bhattacharya, S; Gong, X; Jagota, A; Mukhopadhyay, D; Roxbury, D1
Chen, Y; Dong, Q; Feng, J; Gu, T; Kong, W; Sun, Y; Wang, M; Wu, Y; Yang, X; Zhang, Y1
Hamada, T; Kawakami, K; Kohno, M; Ohara, K1
Al-Jubory, AR; Gitrowski, C; Handy, RD1
Migliario, M; Renò, F; Rizzi, M; Rocchetti, V; Tonello, S1
Hergert, P; Im, J; Jeon, S; Kim, H; Kim, K; Nho, RS; Panyam, J; Yhee, JY; Yoon, HY1
Chen, H; Feng, X; Han, Z; Jia, Y; Li, X; Liu, Q; Liu, X; Tang, H; Wang, A1
Li, Z; Qu, L; Sun, Y; Yang, R; Yin, X1
Glebov, OO1

Reviews

2 review(s) available for chlorpromazine and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing.
    The FEBS journal, 2020, Volume: 287, Issue:17

    Topics: Alveolar Epithelial Cells; Amiloride; Antiviral Agents; Caveolae; Chlorpromazine; Clathrin-Coated Vesicles; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Endocytosis; Endosomes; Humans; Itraconazole; Lung; Lysosomes; Nystatin; Pinocytosis; SARS-CoV-2; Vinblastine; Virus Internalization

2020

Other Studies

25 other study(ies) available for chlorpromazine and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Amiloride; Animals; Carrier Proteins; Chlorpromazine; Glucose; In Vitro Techniques; Intestine, Small; Kinetics; Microvilli; Phenothiazines; Potassium Chloride; Proline; Rabbits; Sodium; Sodium-Hydrogen Exchangers

1988
The effects of vasoactive agents on the proliferation of vascular smooth muscle cells grown in vitro.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Amiloride; Animals; Captopril; Cell Division; Cells, Cultured; Chlorpromazine; In Vitro Techniques; Labetalol; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Propranolol; Quinazolines; Rats; Sulfonamides

1988
Effects of potential damaging agents on the microclimate-pH in the rat jejunum.
    Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:12

    Topics: Acetazolamide; Acetylcysteine; Amiloride; Animals; Aspirin; Chlorpromazine; Glucose; In Vitro Techniques; Intestinal Mucosa; Jejunum; Ouabain; Rats; Rats, Inbred Strains; Taurocholic Acid

1986
A hyperosmotic stimulus regulates intracellular pH, calcium, and S-100 protein levels in avian chondrocytes.
    Biochemical and biophysical research communications, 1996, Oct-14, Volume: 227, Issue:2

    Topics: Amiloride; Animals; Calcium; Cartilage, Articular; Cells, Cultured; Chick Embryo; Chlorpromazine; Cytosol; Epiphyses; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Hypertonic Solutions; Immunohistochemistry; Kinetics; S100 Proteins; Sucrose; Sulfonamides; Time Factors

1996
Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.
    The Journal of biological chemistry, 2000, Apr-07, Volume: 275, Issue:14

    Topics: Amiloride; Animals; Arachidonic Acid; Chlorpromazine; COS Cells; Ion Channel Gating; Lysophosphatidylcholines; Lysophospholipids; Membrane Potentials; Mutagenesis, Site-Directed; Potassium Channels; Potassium Channels, Tandem Pore Domain; Recombinant Proteins; Structure-Activity Relationship; Transfection

2000
Inhibition of Na superset+/H superset+ exchange decreases albumin-induced NF-kappaB activation in renal proximal tubular cell lines (OK and LLC-PK1 cells).
    European journal of medical research, 2001, Oct-29, Volume: 6, Issue:10

    Topics: Amiloride; Animals; Cell Line; Chlorpromazine; DNA; Endocytosis; Guanidines; Kidney Tubules, Proximal; LLC-PK1 Cells; NF-kappa B; Opossums; Serum Albumin, Bovine; Sodium-Hydrogen Exchangers; Sulfones; Swine; Tetradecanoylphorbol Acetate

2001
Intracellular sorting of galectin-8 based on carbohydrate fine specificity.
    Glycobiology, 2007, Volume: 17, Issue:9

    Topics: Amiloride; Animals; beta-Cyclodextrins; Carbohydrates; Cell Membrane; Chlorpromazine; CHO Cells; Cricetinae; Cricetulus; Cytochalasin D; Endocytosis; Galectins; HL-60 Cells; Humans; Kinetics; Sialic Acids; U937 Cells

2007
Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells.
    Journal of virology, 2009, Volume: 83, Issue:10

    Topics: Acetophenones; Actins; Amiloride; Benzopyrans; Cells, Cultured; Chlorpromazine; Clathrin; Cytochalasin D; DNA, Viral; Endothelial Cells; Fibroblasts; Filipin; Gene Expression Regulation, Viral; Herpesvirus 8, Human; Humans; Hydrogen-Ion Concentration; Immediate-Early Proteins; Pinocytosis; rab GTP-Binding Proteins; Trans-Activators; Umbilical Veins; Virus Internalization

2009
[Comparison of mechanisms and cellular uptake of cell-penetrating peptide on different cell lines].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:9

    Topics: Adsorption; Amiloride; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Chloroquine; Chlorpromazine; Dose-Response Relationship, Drug; Exocytosis; Heparin; Humans; Proteoglycans; Temperature; Time Factors

2010
Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides.
    Biochemistry, 2011, Oct-04, Volume: 50, Issue:39

    Topics: Amiloride; Animals; Cattle; Cell-Penetrating Peptides; Chlorpromazine; Cytochalasin D; Endocytosis; HeLa Cells; Humans; Hydrazones; Nystatin; Peptide Fragments; Ribonuclease, Pancreatic; tat Gene Products, Human Immunodeficiency Virus

2011
DNA conjugated SWCNTs enter endothelial cells via Rac1 mediated macropinocytosis.
    Nano letters, 2012, Apr-11, Volume: 12, Issue:4

    Topics: Amiloride; Chlorpromazine; Cytochalasin D; DNA; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Nanotubes, Carbon; Nocodazole; Nystatin; Particle Size; Pinocytosis; rac1 GTP-Binding Protein; Structure-Activity Relationship; Surface Properties

2012
Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Amiloride; Animals; Cell Survival; Chitosan; Chlorpromazine; Dogs; Drug Carriers; Exenatide; Intestinal Absorption; Lactic Acid; Madin Darby Canine Kidney Cells; Male; Models, Biological; Nanoparticles; Particle Size; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Spectrometry, Fluorescence; Venoms

2013
Entry of a cationic lytic-type peptide into the cytoplasm via endocytosis-dependent and -independent pathways in human glioma U251 cells.
    Peptides, 2013, Volume: 50

    Topics: Amiloride; Amino Acid Sequence; Biological Transport; Cations; Cell Line, Tumor; Chlorpromazine; Cytochalasin D; Cytotoxins; Dose-Response Relationship, Drug; Endocytosis; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Molecular Sequence Data; Neuroglia; Peptides; Staining and Labeling; Unilamellar Liposomes; Vesicular Transport Proteins

2013
Uptake of different crystal structures of TiO₂ nanoparticles by Caco-2 intestinal cells.
    Toxicology letters, 2014, May-02, Volume: 226, Issue:3

    Topics: Amiloride; Caco-2 Cells; Cell Survival; Chlorpromazine; Crystallization; Genistein; Humans; Intestinal Mucosa; Intestines; Nanoparticles; Nystatin; Particle Size; Titanium; Vanadates

2014
Low concentrations of neutrophil extracellular traps induce proliferation in human keratinocytes via NF-kB activation.
    Journal of dermatological science, 2017, Volume: 88, Issue:1

    Topics: Adult; Amiloride; Cell Line; Cell Movement; Cell Proliferation; Cell Separation; Chlorpromazine; Dexamethasone; DNA; Extracellular Traps; Healthy Volunteers; Histones; Humans; Keratinocytes; Neutrophils; NF-kappa B; Signal Transduction; Wound Healing

2017
The effects of collagen-rich extracellular matrix on the intracellular delivery of glycol chitosan nanoparticles in human lung fibroblasts.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Amiloride; Cells, Cultured; Chitosan; Chlorpromazine; Collagen Type I; Drug Carriers; Drug Delivery Systems; Endocytosis; Extracellular Matrix; Fibroblasts; Genistein; Humans; Idiopathic Pulmonary Fibrosis; Lung; Nanoparticles; Phosphatidylinositol 3-Kinases

2017
Effect of inhibitors of endocytosis and NF-kB signal pathway on folate-conjugated nanoparticle endocytosis by rat Kupffer cells.
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Amiloride; Animals; Chlorpromazine; Clathrin; Colchicine; Cytokines; Endocytosis; Epirubicin; Folic Acid; Glucans; I-kappa B Proteins; Kupffer Cells; Macrophages; Nanoparticles; NF-kappa B; Nystatin; Pyrrolidines; Rats, Sprague-Dawley; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha

2017
RNA-responsive fluorescent carbon dots for fast and wash-free nucleolus imaging.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Aug-15, Volume: 237

    Topics: Amiloride; beta-Cyclodextrins; Carbon; Cell Membrane; Cell Nucleolus; Chlorpromazine; Endocytosis; Fluorescent Dyes; HeLa Cells; Hep G2 Cells; Humans; Limit of Detection; Molecular Imaging; Quantum Dots; RNA; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors

2020