chlorpromazine and acetaminophen

chlorpromazine has been researched along with acetaminophen in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (31.67)	18.7374
1990's	3 (5.00)	18.2507
2000's	15 (25.00)	29.6817
2010's	21 (35.00)	24.3611
2020's	2 (3.33)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Sherlock, S	1
Arnman, R; Iwarson, S; Olsson, R	1
Funk, C; Knoblauch, M; Lämmli, J	1
Marshall, T; Williams, KM	1
Born, CK; D'Adrea, GH; Davidson, CP; Hamrick, ME; Saville, JG	1
Aw, TY; Kaplowitz, N; Simon, FR; Stolz, A	1
Adelhøj, B; Ibsen, M; Petring, OU; Poulsen, HE	1
Hirayama, C; Yamamoto, T	1
Aber, RC; Noe, JM	1
Beyrich, T; Schleuder, M	1
Nuss, GW; Risley, EA; Van Arman, CG	1
Hochschild, R	1
Vinar, O	1
Trautmann, A	1
Ibrahim, I; Sulman, FG; Weller, CP	1
Luczynska, C; Wilson, K	1
Duniec, Z; Gryglewski, R; Robak, J	1
Deboyser, D; Goethals, F; Krack, G; Roberfroid, M; Vossen, P	1
Salaspuro, M	1
Gryglewski, RJ	1
Hamrick, ME; Harris, SR	1
Corcoran, GB; Gurule, MW; Kamendulis, LM; Ray, SD; Yorkin, RD	1
Aninat, C; Glaise, D; Guguen-Guillouzo, C; Guillouzo, A; Langouët, S; Le Charpentier, T; Morel, F; Piton, A	1
Amacher, DE; Bobrowski, WF; Ganey, PE; Maddox, JF; Roth, RA; Tukov, FF	1
Gandhi, A; Ghose, R; Guo, T	1
Harris, G; Landesmann, B; Mennecozzi, M; Palosaari, T; Whelan, M	1
Antunes, SC; de Oliveira, LL; Gonçalves, F; Nunes, B; Rocha, O	1
Antunes, SC; Gonçalves, F; Nunes, B; Oliveira, LL; Rocha, O	1
Gore, E; Groothuis, GM; Olinga, P; Pennings, JL; Vatakuti, S	1
Alkimin, GD; Barata, C; Daniel, D; Frankenbach, S; Nunes, B; Serôdio, J; Soares, AMVM	1
Chijioke-Nwauche, I; Ikhile, I; Orisakwe, OE	1
Brzeszczyńska, J; Brzeszczyński, F; Hayes, PC; Morgan, K; Morley, SD; Plevris, JN; Samuel, K	1
Babl, FE; Hill, A; Löllgen, RM; Mackay, MT; Palmer, GM	1

Reviews

7 review(s) available for chlorpromazine and acetaminophen

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug-induced hepatotoxicity. Annals of internal medicine, 1986, Volume: 104, Issue:6 Topics: Acetaminophen; Bile; Bile Acids and Salts; Biotransformation; Cell Survival; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Chlorpromazine; Cholestasis; Chronic Disease; Contraceptives, Oral, Hormonal; Cytochrome P-450 Enzyme System; Energy Metabolism; Free Radicals; Glutathione; Humans; Inactivation, Metabolic; Lipid Peroxides; Liver; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Necrosis; Oxidation-Reduction; Oxygen	1986
[Intermediate metabolites and liver toxicity]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:6 Topics: Acetaminophen; Animals; Aspirin; Chlorpromazine; Halothane; Humans; Inactivation, Metabolic; Isoniazid; Liver; Methyldopa; Rats	1985
[Differential indication for the use of neuroleptics]. Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1 Topics: Acetaminophen; Chlorpromazine; Drug Synergism; Fluphenazine; Hallucinations; Humans; Imipramine; Methods; Paranoid Disorders; Placebos; Prochlorperazine; Schizophrenia; Socioeconomic Factors; Thioridazine; Tranquilizing Agents	1970
The clinical significance of the effects of cigarette smoking on drug disposition. Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:7 Topics: Acetaminophen; Antipyrine; Benzodiazepines; Chlorpromazine; Clomipramine; Codeine; Humans; Pharmaceutical Preparations; Phenacetin; Propranolol; Smoking; Theophylline; Warfarin	1983
Evolution of ideas on the role of prostaglandins in inflammation. Agents and actions. Supplements, 1980, Volume: 7 Topics: Acetaminophen; Animals; Arachidonic Acids; Biological Evolution; Butylated Hydroxytoluene; Chlorpromazine; History, 20th Century; Humans; Inflammation; Leukotrienes; Lipid Peroxides; Peroxides; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins G; Rats; Sheep	1980

Trials

1 trial(s) available for chlorpromazine and acetaminophen

Article	Year
Effect of chlorpromazine on drug absorption and gastric emptying in man. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:6 Topics: Acetaminophen; Adult; Chlorpromazine; Double-Blind Method; Female; Gastric Emptying; Humans; Intestinal Absorption; Male	1987

Other Studies

52 other study(ies) available for chlorpromazine and acetaminophen

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Hepatic reactions to drugs. Gut, 1979, Volume: 20, Issue:7 Topics: Acetaminophen; Adenoma; Adult; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Female; Halothane; Humans; Isoniazid; Liver; Liver Neoplasms; Male; Pregnancy	1979
The clinical significance of increased plasma levels of liver-synthesized coagulation factors in liver disease. Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:4 Topics: Acetaminophen; Acute Disease; Biliary Tract Diseases; Blood Coagulation Factors; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Factor VII; Factor X; Gallstones; Hepatitis, Viral, Human; Humans; Liver Diseases; Pancreatic Neoplasms; Prothrombin	1977
[Drug-induced liver diseases]. Gastroenterologische Fortbildungskurse fur die Praxis, 1975, Volume: 5 Topics: Acetaminophen; Adult; Alcoholism; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholestasis; Dihydroxyphenylalanine; Enzyme Induction; Fatty Liver; Female; Granuloma; Halothane; Hepatomegaly; Humans; Male; Middle Aged; Oxyphenisatin Acetate; Pregnancy; Sulfonamides; Tetracycline	1975
Drug interference in the 2,2'-bicinchoninic acid protein assay. Biochemical Society transactions, 1992, Volume: 20, Issue:1 Topics: Acetaminophen; Ampicillin; Artifacts; Ascorbic Acid; Chlorpromazine; Colorimetry; Indicators and Reagents; Penicillin G; Proteins; Quinolines; Serum Albumin, Bovine	1992
Inhibition of acetaminophen hepatotoxicity by chlorpromazine in fed and fasted mice. Biochemical pharmacology, 1988, Jun-15, Volume: 37, Issue:12 Topics: Acetaminophen; Animals; Calcium; Chlorpromazine; Dose-Response Relationship, Drug; Fasting; Glucagon; Glutathione; Liver; Male; Mice; Phosphorylase a	1988
Treatment of fever in burned children. A therapeutic program. Clinical pediatrics, 1973, Volume: 12, Issue:6 Topics: Acetaminophen; Adrenergic alpha-Antagonists; Burns; Child; Child, Preschool; Chlorpromazine; Fever; Humans; Hypotension, Orthostatic; Occlusive Dressings; Tachycardia; Wound Infection	1973
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures]. Die Pharmazie, 1974, Volume: 29, Issue:7 Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine	1974
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:2 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors	1973
Effects of various drugs on longevity in female C57BL-6J mice. Gerontologia, 1973, Volume: 19, Issue:5 Topics: Acetaminophen; Age Factors; Analgesics; Animals; Aspirin; Body Weight; Buffers; Cell Membrane; Chemical Phenomena; Chemistry; Chloroquine; Chlorpheniramine; Chlorpromazine; Female; Glycolates; Longevity; Mice; Mice, Inbred C57BL	1973
[Dialysis of drugs and poisons. 2]. Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44 Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine	1972
Analgesic profile of tranquillizers in multiple screening tests in mice. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1 Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents	1968
Antioxidant properties of some chemicals vs their influence on cyclooxygenase and lipoxidase activities. Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14 Topics: Acetaminophen; Animals; Antioxidants; Arachidonic Acids; Caffeic Acids; Chlorpromazine; In Vitro Techniques; Lipid Peroxides; Lipoxygenase; Microsomes, Liver; Prostaglandin-Endoperoxide Synthases; Rats	1983
Critical biochemical functions of isolated hepatocytes as sensitive indicators of chemical toxicity. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:3 Pt 1 Topics: Acetaminophen; Animals; Bromobenzenes; Chlorpromazine; Cytochrome P-450 Enzyme System; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Glycogen; Male; Mixed Function Oxygenases; Promethazine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Time Factors	1984
[Drug-induced liver damage; new aspects on its mechanism]. Duodecim; laaketieteellinen aikakauskirja, 1980, Volume: 96, Issue:5 Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Estrogens; Female; Halothane; Humans; Isoniazid; Liver; Methyldopa; Oxyphenisatin Acetate	1980
Antagonism of acetaminophen hepatotoxicity by phospholipase A2 inhibitors. Research communications in chemical pathology and pharmacology, 1993, Volume: 79, Issue:1 Topics: Acetaminophen; Animals; Calcium; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlorpromazine; Diltiazem; DNA; Homeostasis; Male; Mice; Mitochondria, Liver; NADP; Oxidation-Reduction; Phospholipases A; Phospholipases A2	1993
Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1993, Volume: 7, Issue:5 Topics: Acetaminophen; Animals; Biotransformation; Calcium; Calcium Channel Blockers; Cell Death; Chlorpromazine; DNA Damage; Liver; Male; Mice; Necrosis; Verapamil	1993
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1 Topics: Acetaminophen; Aflatoxin B1; Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chlorpromazine; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Gene Expression; Gene Expression Profiling; Glucuronosyltransferase; Hepatocytes; Humans; Inhibitory Concentration 50; Isoenzymes; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xenobiotics	2006
Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system. Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:8 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antipsychotic Agents; Carcinogens; Cell Separation; Chlorpromazine; Coculture Techniques; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Hepatocytes; Humans; Immunoassay; Immunohistochemistry; Inflammation; Kupffer Cells; Lipopolysaccharides; Male; Monocrotaline; Potassium Chloride; Propanols; Rats; Rats, Sprague-Dawley	2006
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes. The Journal of toxicological sciences, 2010, Volume: 35, Issue:2 Topics: Acetaminophen; Animals; Cells, Cultured; Chlorpromazine; Hepatocytes; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha	2010
Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro? PloS one, 2015, Volume: 10, Issue:4 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Calcium; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chlorpromazine; Diclofenac; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Omeprazole; Primary Cell Culture; Sex Characteristics; Verapamil	2015
Acute and chronic ecotoxicological effects of four pharmaceuticals drugs on cladoceran Daphnia magna. Drug and chemical toxicology, 2016, Volume: 39, Issue:1 Topics: Acetaminophen; Animals; Chlorpromazine; Daphnia; Diclofenac; Dose-Response Relationship, Drug; Female; Propranolol; Rats, Wistar; Reproduction; Toxicity Tests, Acute; Toxicity Tests, Chronic; Water Pollutants, Chemical	2016
Evaluation of ecotoxicological effects of drugs on Daphnia magna using different enzymatic biomarkers. Ecotoxicology and environmental safety, 2015, Volume: 119 Topics: Acetaminophen; Animals; Biomarkers; Catalase; Chlorpromazine; Daphnia; Diclofenac; Ecotoxicology; Environmental Exposure; Glutathione Peroxidase; Glutathione Transferase; Oxidative Stress; Prescription Drugs; Propranolol	2015
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3 Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis; Colchicine; Cyclosporine; Diethylnitrosamine; Drug-Related Side Effects and Adverse Reactions; Ethinyl Estradiol; Female; Gene Expression Profiling; Hepatocytes; Humans; Liver; Male; Methyltestosterone; Middle Aged; Necrosis; Phenotype; Toxicogenetics; Young Adult	2016
Evaluation of pharmaceutical toxic effects of non-standard endpoints on the macrophyte species Lemna minor and Lemna gibba. The Science of the total environment, 2019, Mar-20, Volume: 657 Topics: Acetaminophen; Anthocyanins; Aquatic Organisms; Araceae; Carotenoids; Catalase; Chlorophyll A; Chlorpromazine; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Ecotoxicology; Environmental Biomarkers; Water Pollutants, Chemical	2019
Childhood Drug and Non-Drug Poisoning in Nigeria: An Economic Appraisal. Annals of global health, 2019, 07-09, Volume: 85, Issue:1 Topics: Acetaminophen; Adolescent; Age Distribution; Amitriptyline; Analgesics, Non-Narcotic; Antipsychotic Agents; Carbon Monoxide Poisoning; Child; Child, Preschool; Chlorpromazine; Ethanol; Female; Ferrous Compounds; Health Care Costs; Humans; Infant; Infant, Newborn; Kerosene; Length of Stay; Male; Nigeria; Organophosphate Poisoning; Poisoning; Prevalence; Retrospective Studies; Rodenticides; Sex Distribution; Snake Bites	2019
Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling. Cells, 2020, 03-21, Volume: 9, Issue:3 Topics: Acetaminophen; Adenosine Triphosphate; Cell Line; Cell Survival; Chlorpromazine; Disease; Gene Expression Regulation; Genes, Essential; Humans; Models, Biological; Real-Time Polymerase Chain Reaction; Reference Standards; RNA, Messenger; Toxicity Tests; Transcription, Genetic	2020
Intravenous chlorpromazine for acute paediatric migraine. Emergency medicine Australasia : EMA, 2022, Volume: 34, Issue:4 Topics: Acetaminophen; Child; Chlorpromazine; Emergency Service, Hospital; Humans; Ibuprofen; Migraine Disorders; Retrospective Studies	2022