Compounds > chlorpromazine

chlorpromazine and 8-hydroxy-2-(di-n-propylamino)tetralin

chlorpromazine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's7 (46.67)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF1
Amlaiky, N; Hen, R; Plassat, JL1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Glennon, RA1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S1
Gudelsky, GA; Meltzer, HY; Nash, JF1
Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT1
Muck-Seler, D; Pericić, D1
Ruiz-Ortega, JA; Ugedo, L1
Ahlemeyer, B; Krieglstein, J1
Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J1
Matsuoka, N; Mutoh, S; Shirakawa, K; Tada, M1

Reviews

1 review(s) available for chlorpromazine and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

14 other study(ies) available for chlorpromazine and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
    Journal of medicinal chemistry, 1993, Apr-16, Volume: 36, Issue:8

    Topics: Animals; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines

2019
Antagonism of serotonin receptor mediated neuroendocrine and temperature responses by atypical neuroleptics in the rat.
    European journal of pharmacology, 1988, Jul-14, Volume: 151, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Body Temperature; Butyrophenones; Chlorpromazine; Clozapine; Corticosterone; Haloperidol; Male; Neurosecretory Systems; Pyrazines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1988
Effects of atypical antipsychotic agents on social behavior in rodents.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior

1993
Possible antidepressant dihydroergosine preferentially binds to 5-HT1B receptor sites in the rat hippocampus.
    Journal of neural transmission. General section, 1993, Volume: 92, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Binding, Competitive; Chlorpromazine; Ergotamines; Hippocampus; In Vitro Techniques; Male; Pindolol; Quinoxalines; Rats; Rats, Wistar; Receptors, Serotonin

1993
Activation of 5-HT1A receptors potentiates the clonidine inhibitory effect in the locus coeruleus.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chlorpromazine; Clonidine; Dopamine Antagonists; Dose-Response Relationship, Drug; Injections, Intravenous; Isoquinolines; Locus Coeruleus; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1997
Stimulation of 5-HT1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo.
    Brain research, 1997, Nov-28, Volume: 777, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Aminopyridines; Animals; Apoptosis; Cells, Cultured; Chick Embryo; Chlorpromazine; Culture Media, Serum-Free; Dopamine Antagonists; Nerve Growth Factors; Neurons; Neuroprotective Agents; Piperazines; Propranolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Telencephalon

1997
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine

2001
Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine.
    Psychopharmacology, 2004, Volume: 176, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Catalepsy; Chlorpromazine; Dibenzothiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Haloperidol; Hyperkinesis; Injections, Intraperitoneal; Male; Methamphetamine; Mice; Piperazines; Pyridines; Quetiapine Fumarate; Receptor, Serotonin, 5-HT1A; Risperidone; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists

2004