chlorpheniramine and verapamil

chlorpheniramine has been researched along with verapamil in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (13.89)	18.7374
1990's	4 (11.11)	18.2507
2000's	14 (38.89)	29.6817
2010's	12 (33.33)	24.3611
2020's	1 (2.78)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Keserü, GM	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Caron, G; Ermondi, G	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Cooper, RA; Dodean, RA; Hinrichs, DJ; Janowsky, A; Johnson, RA; Kelly, JX; Lane, KD; Riscoe, M; Smilkstein, MJ; Winter, R	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Barrow, RA; Deane, KJ; Lehane, AM; Martin, RE; Summers, RL	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bertaccini, G; Coruzzi, G; Vitali, T	1
Pillai, G; Sutter, MC	1
Merrill, GF; Tozzi, CA	1
Dorrell, SG; Merrill, GF; Tozzi, CA	1
Kajiwara, A; Ohizumi, Y; Yasumoto, T	1
Jones, R; Kilbane, E; Klette, K; Levine, B; Smith, ML	1
Ikeda, M; Koshika, A; Miyajima, M; Okada, J	1
Feng, J; Fu, RN; Gu, JL; Han, JH; Ma, LY; Wang, H	1
Gbotosho, GO; Gerena, L; Happi, CT; Kyle, DE; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Salako, LA; Sowunmi, A	1
Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y	1
Douroumis, D; Farrell, TP; Levina, M; Maniruzzaman, M; Morgan, DJ; Nokhodchi, A; Palmer, D; Rajabi-Siahboomi, AR	1
Bo, C; Gong, B; Guo, S; Huang, C; Ma, S; Ou, J; Zhang, N	1

Reviews

1 review(s) available for chlorpheniramine and verapamil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

35 other study(ies) available for chlorpheniramine and verapamil

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Acridones; Animals; Antimalarials; Cell Survival; Cells, Cultured; Drug Design; Drug Interactions; Drug Resistance, Multiple; Lymphocytes; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Molecular Structure; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT. ACS medicinal chemistry letters, 2014, May-08, Volume: 5, Issue:5 Topics:	2014
Effect of histamine and related compounds on the papillary muscle of the guinea pig. Pharmacological research communications, 1978, Volume: 10, Issue:8 Topics: Animals; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Papillary Muscles; Pyrilamine; Structure-Activity Relationship; Verapamil	1978
Effect of human plasma proteins on spontaneous contractile activity of rat mesenteric portal vein. Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:6 Topics: Alpha-Globulins; Animals; Atropine; Beta-Globulins; Blood Proteins; Chlorpheniramine; gamma-Globulins; Humans; Immunoglobulin G; Ketanserin; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Portal Vein; Rats; Rats, Inbred Strains; Saralasin; Serum Albumin; Verapamil	1990
Differential effects of adenosine and verapamil on histamine vascular contractions. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:6 Topics: Adenosine; Animals; Calcium; Chlorpheniramine; Histamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Verapamil	1986
Evidence of histamine-induced myocardial ischaemia: reversal by chlorpheniramine and potentiation by atherosclerosis. Cardiovascular research, 1985, Volume: 19, Issue:12 Topics: Animals; Arteriosclerosis; Chlorpheniramine; Cimetidine; Coronary Circulation; Coronary Disease; Coronary Vessels; Histamine; Male; Rabbits; Verapamil	1985
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1 Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Chlorpheniramine; Dose-Response Relationship, Drug; Guinea Pigs; Ion Channels; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Oxocins; Phentolamine; Reserpine; Tetrodotoxin; Vas Deferens; Verapamil	1983
An intoxication involving BRON and verapamil. Journal of analytical toxicology, 1993, Volume: 17, Issue:6 Topics: Adult; Caffeine; Chlorpheniramine; Codeine; Drug Combinations; Ephedrine; Humans; Male; Suicide; Verapamil	1993
Effect of polymer/basic drug interactions on the two-stage diffusion-controlled release from a poly(L-lactic acid) matrix. Journal of controlled release : official journal of the Controlled Release Society, 1999, Sep-20, Volume: 61, Issue:3 Topics: Biocompatible Materials; Chlorpheniramine; Crystallization; Delayed-Action Preparations; Diffusion; Diltiazem; Drug Interactions; Kinetics; Lactic Acid; Papaverine; Polyesters; Polymers; Verapamil; Water; X-Ray Diffraction	1999
[A novel chiral selector in capillary electrophoresis--beta-cyclodextrin polymer]. Se pu = Chinese journal of chromatography, 1999, Volume: 17, Issue:6 Topics: Anti-Allergic Agents; beta-Cyclodextrins; Chlorpheniramine; Cyclodextrins; Electrophoresis, Capillary; Lobeline; Polymers; Stereoisomerism; Vasodilator Agents; Verapamil	1999
The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum. Annals of tropical medicine and parasitology, 2006, Volume: 100, Issue:7 Topics: Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Chlorpheniramine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Enzyme Inhibitors; Histamine H1 Antagonists; Orosomucoid; Plasmodium falciparum; Promethazine; Verapamil	2006
Pharmacophore modeling for hERG channel facilitation. Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1 Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis	2012
Mechanism of synergistic interactions and its influence on drug release from extended release matrices manufactured using binary mixtures of polyethylene oxide and sodium carboxymethylcellulose. Colloids and surfaces. B, Biointerfaces, 2013, Apr-01, Volume: 104 Topics: Calorimetry; Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Chlorpheniramine; Cyclohexanols; Drug Synergism; Photoelectron Spectroscopy; Polyethylene Glycols; Propranolol; Tablets; Time Factors; Venlafaxine Hydrochloride; Verapamil	2013
Enantioseparation in high performance liquid chromatography: preparation and evaluation of a vancomycin-based chiral stationary phase Analytical methods : advancing methods and applications, 2022, 03-24, Volume: 14, Issue:12 Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Fluoxetine; Isoproterenol; Polymerization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Vancomycin; Verapamil	2022