chlorpheniramine and pyrilamine

chlorpheniramine has been researched along with pyrilamine in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (46.97)	18.7374
1990's	23 (34.85)	18.2507
2000's	11 (16.67)	29.6817
2010's	1 (1.52)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Caron, G; Ermondi, G	1
Ahman, M; Holmén, AG; Wan, H	1
Chen, G; Huang, G; Zhou, S	1
Cooper, A; Jones, D; Major, J; Scholes, P; Walters, M; Wilde, C	1
Hill, SJ; Marrian, DH; Young, JM	1
Bertaccini, G; Coruzzi, G; Vitali, T	1
Bhattacharya, BK; Dadkar, NK; Dohadwalla, AN	1
Panagides, J; Tolman, EL	1
Balster, RL; Beardsley, PM	1
Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Meguro, K; Takahashi, T; Watanabe, T; Yanai, K; Yokoyama, H	1
Fukui, H; Inagaki, N; Ito, S; Wada, H; Yamatodani, A	1
Fukuda, K; Kuno, T; Matsumura, F; Motoyoshi, H; Nagata, Y; Tanaka, S; Yamasaki, H	1
Bergman, J	1
Carron, R; Martin, ML; Montero, MJ; Ortiz de Urbina, AV; San Roman, L; Sevilla, MA	1
Fukui, H; Inagaki, N; Kanamura, A; Kondou, H; Koyama, Y; Wada, H	1
Edvinsson, L; Hill, SJ; Ottosson, A	1
Bouthenet, ML; Ganellin, CR; Ruat, M; Schwartz, JC	1
Ido, T; Ishiwata, K; Itoh, M; Matsuzawa, T; Watanabe, T; Yagi, N; Yanai, K	1
Donnelly, A; Gellhaus, M; Weiler, JM; Weiler, K	1
Fujimoto, K; Fukagawa, K; Ookuma, K; Sakata, T; Shiraishi, T; Wada, H; Yoshimatsu, H	1
Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM	1
Taylor, DJ; Woolley, DE	2
Hanig, JP; Hui, FW; Sun, CL	1
Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S	1
White, JM	1
Banks, RO; Jacobson, ED	1
Katona, PG; Rigel, DF	1
Fleisch, JH; Haisch, KD; Rinkema, LE; Whitesitt, CA	1
Fu, SX; Li, CG; Li, YS	1
Dveksler, G; Franchi, AM; Gimeno, AL; Gimeno, MF; Viggiano, M	1
Itoh, Y; Nishibori, M; Oishi, R; Saeki, K	1
Clay, TP; Miller, P; Stead, H	1
Niemegeers, CJ; Wauquier, A	1
Awouters, F; Janssen, PA; Van den Broeck, WA; Wauquier, A	1
Church, MK; Gradidge, CF	1
Arrang, JM; Duchemin, AM; Garbarg, M; Quach, TT; Rose, C; Schwartz, JC	1
Boyce, MJ; Harvey, CA; Owen, DA	1
De Fabrizio, F	1
Diffley, D; Snyder, SH; Tran, VT	1
Bembry, J; Bertrand, N; Merkel, N; Spatz, M; Stanimirovic, DB	1
Danielson, ND; Holeman, JA	1
Guinosso, PJ; Jurkiewicz, NK; Lynch, JJ; Salata, JJ; Stupienski, RF; Wallace, AA	1
Ellis, JL; Undem, BJ	1
Leurs, R; Smit, MJ; Tensen, CP; Ter Laak, AM; Timmerman, H	1
Arias-Montaño, JA; Young, JM	1
KAMEI, CH	1
Fu, LW; Longhurst, JC; Pan, HL	1
De Souza-Silva, MA; Dringenberg, HC; Huston, JP; Rossmüller, J; Schwarting, RK	1
Cunningham, FM; Foster, AP	1
de Souza-Silva, MA; Dringenberg, HC; Huston, JP; Schwarting, RK	1
Chen, Z; Kamei, C; Kaneko, Y; Saitou, K; Sugimoto, Y	1
Hashimoto, Y; Katsuyama, S; Kuramasu, A; Kutsuwa, M; Lin, ZY; Mobarakeh, JI; Sakurada, S; Watanabe, T; Yanai, K	1
Akaishi, Y; Hattori, Y; Kanno, M; Kitabatake, A; Yasuda, K; Yoshimoto, K	1
Lutz, TA; Meier, S; Mollet, A; Riediger, T	1
BODI, T; FUCHS, M; HERNANDO, L; MALLIN, SR; MOYER, JH	1
STILLWATER, RB; VILLANYI, L	1
EPSTEIN, JI; KAPLAN, H; SHERWOOD, H	1
Fukui, H; Horio, S; Ichikawa, T; Ikoma, Y; Ishimura, K; Matsuyama, K; Nitta, Y	1
Chatelain, P; Christophe, B; Gillard, M; Gupta, A; Hammarlund-Udenaes, M; Massingham, R	1
Bai, ZT; Chai, ZF; Ji, YH; Jiang, F; Liu, T; Pang, XY	1
Adhoum, N; Jebali, S; Loueslati, MH; Louhaichi, MR; Monser, L	1

Reviews

1 review(s) available for chlorpheniramine and pyrilamine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000

Trials

1 trial(s) available for chlorpheniramine and pyrilamine

Article	Year
Randomized, double-blind, parallel groups, placebo-controlled study of efficacy and safety of Rynatan in the treatment of allergic rhinitis using an acute model. Annals of allergy, 1990, Volume: 64, Issue:1 Topics: Adolescent; Adult; Aged; Aminopyridines; Chlorpheniramine; Double-Blind Method; Drug Combinations; Humans; Middle Aged; Phenylephrine; Placebos; Pyrilamine; Rhinitis, Allergic, Seasonal	1990

Article

Year

Randomized, double-blind, parallel groups, placebo-controlled study of efficacy and safety of Rynatan in the treatment of allergic rhinitis using an acute model.

Annals of allergy, 1990, Volume: 64, Issue:1

Topics: Adolescent; Adult; Aged; Aminopyridines; Chlorpheniramine; Double-Blind Method; Drug Combinations; Humans; Middle Aged; Phenylephrine; Placebos; Pyrilamine; Rhinitis, Allergic, Seasonal

1990

Other Studies

64 other study(ies) available for chlorpheniramine and pyrilamine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Design, synthesis and biological activity of a novel ethylenediamine derivatives as H Bioorganic & medicinal chemistry, 2019, 12-15, Volume: 27, Issue:24 Topics: Animals; Basophils; Cell Line; Chlorpheniramine; Drug Design; Ethylenediamines; Female; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Mice; Models, Molecular; Molecular Structure; Protein Conformation; Random Allocation; Rats; Receptors, Histamine H1	2019
Characterization of an adenylate cyclase system sensitive to histamine H2-receptor excitation in cells from dog gastric mucosa. Agents and actions, 1976, Volume: 6, Issue:6 Topics: Adenylyl Cyclase Inhibitors; Animals; Burimamide; Cells; Chlorpheniramine; Cyclic AMP; Dogs; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Kinetics; Methylhistamines; Metiamide; Promethazine; Pyrilamine	1976
Specific binding of 3H-mepyramine to histamine H1 receptors in intestinal smooth muscle. Nature, 1977, Nov-24, Volume: 270, Issue:5635 Topics: Animals; Binding, Competitive; Chlorpheniramine; Guinea Pigs; In Vitro Techniques; Intestine, Small; Kinetics; Muscle, Smooth; Promethazine; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Triprolidine	1977
Effect of histamine and related compounds on the papillary muscle of the guinea pig. Pharmacological research communications, 1978, Volume: 10, Issue:8 Topics: Animals; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Papillary Muscles; Pyrilamine; Structure-Activity Relationship; Verapamil	1978
Influence of pheniramine and chlorpheniramine on apomorphine induced compulsive gnawing in mice. Psychopharmacology, 1976, Jul-09, Volume: 48, Issue:1 Topics: Animals; Apomorphine; Behavior, Animal; Chlorpheniramine; Compulsive Behavior; Dopamine; Drug Synergism; Female; Humans; Male; Mice; Parasympathetic Nervous System; Pheniramine; Pyrilamine	1976
Effect of various pharmacological agents on prostaglandin induced increases in microvascular permeability. Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Atropine; Capillary Permeability; Chlorpheniramine; Epinephrine; Isoproterenol; Male; Methysergide; Phenoxybenzamine; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrilamine; Rats; Stimulation, Chemical; Vasoconstrictor Agents	1975
The intravenous self-administration of antihistamines by rhesus monkeys. Drug and alcohol dependence, 1992, Volume: 30, Issue:2 Topics: Animals; Benzhydryl Compounds; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Hydroxyzine; Macaca mulatta; Male; Motivation; Pyrilamine; Self Administration; Substance-Related Disorders; Tripelennamine	1992
Histamine H1 receptors in human brain visualized in vivo by [11C]doxepin and positron emission tomography. Neuroscience letters, 1992, Mar-30, Volume: 137, Issue:2 Topics: Adult; Brain; Carbon Isotopes; Chlorpheniramine; Doxepin; Humans; Injections, Intravenous; Male; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed	1992
Single type-2 astrocytes show multiple independent sites of Ca2+ signaling in response to histamine. Proceedings of the National Academy of Sciences of the United States of America, 1991, May-15, Volume: 88, Issue:10 Topics: Animals; Astrocytes; Calcium; Calcium Channels; Chlorpheniramine; Fluorescent Dyes; Fura-2; Histamine; Inositol 1,4,5-Trisphosphate; Kinetics; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Signal Transduction	1991
Histamine H1-receptor-mediated keratan sulfate production in rabbit chondrocytes: involvement of protein kinase C. The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1 Topics: Animals; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Keratan Sulfate; Kinetics; Methylhistamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrilamine; Rabbits; Receptors, Histamine H1; Sphingosine	1991
Psychomotor stimulant effects of the stereoisomers of chlorpheniramine. Psychopharmacology, 1990, Volume: 100, Issue:1 Topics: Animals; Binding, Competitive; Central Nervous System Stimulants; Chlorpheniramine; Cocaine; Dose-Response Relationship, Drug; Male; Pyrilamine; Reinforcement Schedule; Saimiri; Stereoisomerism	1990
Antihistaminic activity of pulegone on the guinea-pig ileum. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:4 Topics: Animals; Chlorpheniramine; Cyclohexane Monoterpenes; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Male; Menthol; Monoterpenes; Muscle, Smooth, Vascular; Pyrilamine	1990
Histamine-induced inositol phosphate accumulation in type-2 astrocytes. Biochemical and biophysical research communications, 1991, Jun-14, Volume: 177, Issue:2 Topics: Animals; Astrocytes; Cells, Cultured; Chlorpheniramine; Famotidine; Histamine; Inositol Phosphates; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine	1991
Histamine receptors in brain vessels of guinea-pig: in-vitro pharmacology and ligand binding. Acta physiologica Scandinavica, 1990, Volume: 140, Issue:1 Topics: Animals; Basilar Artery; Brain; Calcium; Calcium Channels; Cerebrovascular Circulation; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Ligands; Nimodipine; Pyrilamine; Receptors, Histamine; Vasoconstriction	1990
Histamine H1-receptor in heart: unique electrophoretic mobility and autoradiographic localization. Journal of neurochemistry, 1990, Volume: 55, Issue:2 Topics: Affinity Labels; Animals; Autoradiography; Cell Membrane; Cerebellum; Chlorpheniramine; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Heart Atria; Ileum; Iodine Radioisotopes; Lung; Male; Mianserin; Molecular Weight; Myocardium; Photochemistry; Pyrilamine; Receptors, Histamine H1; Succinimides	1990
Specific binding of [3H]pyrilamine to histamine H1 receptors in guinea pig brain in vivo: determination of binding parameters by a kinetic four-compartment model. Journal of neurochemistry, 1990, Volume: 55, Issue:2 Topics: Aminopyridines; Animals; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Chlorpheniramine; Corpus Striatum; Guinea Pigs; Hippocampus; Kinetics; Male; Mathematics; Models, Biological; Pyrilamine; Receptors, Histamine H1; Stereoisomerism; Thalamus; Tissue Distribution; Tritium	1990
Neuronal histamine modulates feeding behavior through H1-receptor in rat hypothalamus. The American journal of physiology, 1989, Volume: 256, Issue:3 Pt 2 Topics: Animals; Chlorpheniramine; Cimetidine; Drinking Behavior; Famotidine; Feeding Behavior; Histamine; Histamine H2 Antagonists; Hypothalamus; Injections, Intraventricular; Male; Motor Activity; Neurons; Promethazine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Reference Values; Thiazoles	1989
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine	1989
Evidence for both histamine H1 and H2 receptors on human articular chondrocytes. Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6 Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamine; Humans; Prostaglandins E; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Tripelennamine	1987
Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice. Neuropharmacology, 1985, Volume: 24, Issue:1 Topics: Analgesics; Animals; Chlorpheniramine; Cyclizine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Male; Mice; Morphine; Phenothiazines; Pyrilamine	1985
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man. British journal of pharmacology, 1985, Volume: 85, Issue:1 Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin	1985
The discriminative stimulus properties of mepyramine. Life sciences, 1985, Sep-23, Volume: 37, Issue:12 Topics: Aminopyridines; Animals; Chlorpheniramine; Discrimination, Psychological; Histamine H1 Antagonists; Imipramine; Male; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Scopolamine	1985
Renal vasodilation with ureteral occlusion and prostaglandins: attenuation by histamine H1 antagonists. The American journal of physiology, 1985, Volume: 249, Issue:6 Pt 2 Topics: Alprostadil; Animals; Blood Pressure; Bradykinin; Chlorpheniramine; Cimetidine; Dinoprostone; Dogs; Epoprostenol; Female; Glomerular Filtration Rate; Histamine H1 Antagonists; Kidney; Male; Mathematics; Meclofenamic Acid; Methylhistamines; Prostaglandin D2; Prostaglandins; Prostaglandins A; Prostaglandins D; Prostaglandins E; Pyrilamine; Regional Blood Flow; Ureter; Vasodilation	1985
Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1 Topics: Anesthetics, Local; Animals; Atropine; Chlorpheniramine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Lidocaine; Male; Procaine; Promethazine; Pyrilamine; Tachycardia	1986
Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist. Agents and actions, 1987, Volume: 20, Issue:1-2 Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Chlorpheniramine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Muscle, Smooth; Promethazine; Pyrilamine; Terfenadine; Triprolidine	1987
Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists. Annals of the rheumatic diseases, 1987, Volume: 46, Issue:6 Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine H1 Antagonists; Humans; Prostaglandins E; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Synovial Membrane; Tripelennamine	1987
[Arrhythmogenic effects of histamine on ischemic hearts of guinea pigs]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:6 Topics: Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Cricetinae; Female; Heart Rate; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Myocardial Infarction; Pyrilamine	1987
Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation? Prostaglandins, leukotrienes, and medicine, 1987, Volume: 28, Issue:3 Topics: Alprostadil; Animals; Aspirin; Chlorpheniramine; Cimetidine; Dinoprost; Dinoprostone; Female; Histamine; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrilamine; Quinacrine; Rats; Receptors, Histamine; Receptors, Histamine H1; Stimulation, Chemical; Uterine Contraction	1987
Mechanism of the central hyperglycemic action of histamine in mice. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpheniramine; Chromatography, High Pressure Liquid; Corticosterone; Dose-Response Relationship, Drug; Epinephrine; Histamine; Hyperglycemia; Mice; Norepinephrine; Phentolamine; Promethazine; Propranolol; Pyrilamine; Pyrimethamine; Receptors, Histamine H1; Receptors, Histamine H2; Time Factors	1987
A lung perfusion technique for the detection of antigenic intrapulmonary bronchoconstriction and its mediation. Journal of pharmacological methods, 1985, Volume: 14, Issue:3 Topics: Animals; Antigens; Bronchi; Chlorpheniramine; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Perfusion; Pressure; Pyrazoles; Pyrilamine; Respiratory Hypersensitivity	1985
Effects of chlorpheniramine, pyrilamine and astemizole on intracranial self-stimulation in rats. European journal of pharmacology, 1981, Jun-19, Volume: 72, Issue:2-3 Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Histamine H1 Antagonists; Neurotransmitter Agents; Physostigmine; Pupil; Pyrilamine; Rats; Self Stimulation	1981
A comparison between astemizole and other antihistamines on sleep-wakefulness cycles in dogs. Neuropharmacology, 1981, Volume: 20, Issue:9 Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Diphenhydramine; Dogs; Histamine H1 Antagonists; Ketotifen; Male; Periodicity; Pyrilamine; Sleep; Sleep Stages; Sleep, REM; Wakefulness	1981
Inhibition of histamine release from human lung in vitro by antihistamines and related drugs. British journal of pharmacology, 1980, Volume: 69, Issue:4 Topics: Chlorpheniramine; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; Lung; Mast Cells; Pyrilamine	1980
Histamine-induced responses in mammalian brain slices: characterization of H1 and H2 receptors. Advances in biochemical psychopharmacology, 1983, Volume: 37 Topics: Animals; Brain; Chlorpheniramine; Cyclic AMP; Glycogen; Guinea Pigs; Hippocampus; Imidazoles; Impromidine; In Vitro Techniques; Kinetics; Mice; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2	1983
Effects of histamine on the circulatory system. Klinische Wochenschrift, 1982, Sep-01, Volume: 60, Issue:17 Topics: Animals; Cardiovascular System; Cats; Chlorpheniramine; Cimetidine; Dogs; Hemodynamics; Histamine; Humans; Pyrilamine; Time Factors	1982
Simultaneous GLC analysis of salicylamide, phenylpropanolamine hydrochloride, caffeine, chlorpheniramine maleate, phenylephrine hydrochloride, and pyrilamine maleate in capsule preparations. Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:7 Topics: Aminopyridines; Caffeine; Capsules; Chlorpheniramine; Chromatography, Gas; Phenylephrine; Phenylpropanolamine; Pyrilamine; Salicylamides	1980
Histamine H1-receptors labeled in vivo: antidepressant and antihistamine interactions. European journal of pharmacology, 1980, Jun-13, Volume: 64, Issue:2-3 Topics: Animals; Antidepressive Agents; Binding Sites; Brain; Chlorpheniramine; Drug Interactions; Histamine Antagonists; In Vitro Techniques; Isotope Labeling; Mice; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Time Factors; Tritium	1980
Interaction between histamine and adenosine in human cerebromicrovascular endothelial cells: modulation of second messengers. Metabolic brain disease, 1994, Volume: 9, Issue:3 Topics: Adenosine; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Endothelium, Vascular; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Pyrilamine; Receptors, Histamine; Receptors, Purinergic P1; Second Messenger Systems	1994
Liquid chromatography of antihistamines using post-column tris(2,2'-bipyridine) ruthenium(III) chemiluminescence detection. Journal of chromatography. A, 1994, Sep-23, Volume: 679, Issue:2 Topics: 2,2'-Dipyridyl; Brompheniramine; Chlorpheniramine; Chromatography, High Pressure Liquid; Diphenhydramine; Histamine H1 Antagonists; Luminescent Measurements; Organometallic Compounds; Pheniramine; Pyrilamine; Ruthenium; Spectrophotometry, Ultraviolet	1994
Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine. Circulation research, 1995, Volume: 76, Issue:1 Topics: Action Potentials; Animals; Astemizole; Chlorpheniramine; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Potassium Channels; Pyrilamine; Refractory Period, Electrophysiological; Terfenadine	1995
Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1 Topics: Bronchi; Chlorpheniramine; Dicarboxylic Acids; Female; Histamine; Humans; Hydroxyurea; In Vitro Techniques; Indazoles; Isometric Contraction; Isotonic Solutions; Leukotriene D4; Lipoxygenase Inhibitors; Male; Middle Aged; Muscle Tonus; Muscle, Smooth; Pyrilamine; SRS-A	1994
Site-directed mutagenesis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists. Biochemical and biophysical research communications, 1994, May-30, Volume: 201, Issue:1 Topics: Animals; Asparagine; Base Sequence; Chlorpheniramine; DNA Primers; Guinea Pigs; Histamine; Histamine Agonists; Inositol Phosphates; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship	1994
Characteristics of histamine H1 receptors on HeLa cells. European journal of pharmacology, 1993, May-15, Volume: 245, Issue:3 Topics: Binding Sites; Cell Membrane; Chlorpheniramine; HeLa Cells; Histamine; Humans; Inositol Phosphates; Pyrilamine; Receptors, Histamine H1	1993
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR. Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Iris; Lethal Dose 50; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Piperidines; Potassium; Pyrilamine; Ranitidine; Receptors, Histamine H1; Substance P	1996
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors. The American journal of physiology, 1997, Volume: 273, Issue:6 Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; Duodenum; Female; Gallbladder; Histamine; Histamine H1 Antagonists; Indomethacin; Ischemia; Male; Methylhistamines; Nerve Fibers; Neural Conduction; Pancreas; Pyrilamine; Receptors, Histamine H1	1997
Histamine H1 receptor antagonists produce increases in extracellular acetylcholine in rat frontal cortex and hippocampus. Journal of neurochemistry, 1998, Volume: 70, Issue:4 Topics: Acetylcholine; Animals; Chlorpheniramine; Extracellular Space; Frontal Lobe; Hippocampus; Histamine H1 Antagonists; Male; Pyrilamine; Rats; Rats, Wistar; Sodium Chloride	1998
Histamine-induced adherence and migration of equine eosinophils. American journal of veterinary research, 1998, Volume: 59, Issue:9 Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Chlorpheniramine; Eosinophils; Female; Fibronectins; Histamine; Histamine H1 Antagonists; Horses; Integrin alpha4beta1; Integrins; Male; Plastics; Pyrilamine; Receptors, Histamine; Receptors, Lymphocyte Homing; Surface Properties	1998
Increased levels of extracellular dopamine in neostriatum and nucleus accumbens after histamine H1 receptor blockade. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:4 Topics: Animals; Chlorpheniramine; Dopamine; Histamine H1 Antagonists; Male; Microdialysis; Neostriatum; Nucleus Accumbens; Pyrilamine; Rats; Rats, Wistar	1998
Slow wave sleep-inducing effects of first generation H1-antagonists. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:10 Topics: Animals; Azepines; Chlorpheniramine; Diphenhydramine; Electroencephalography; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Pyrilamine; Rats; Rats, Wistar; Sleep	1999
Role of histamine H(1) receptor in pain perception: a study of the receptor gene knockout mice. European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2 Topics: Animals; Behavior, Animal; Capsaicin; Chlorpheniramine; Formaldehyde; Histamine H1 Antagonists; Hot Temperature; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrilamine; Reaction Time; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; Stereoisomerism	2000
Involvement of tyrosine phosphorylation in the positive inotropic effect produced by H(1)-receptors with histamine in guinea-pig left atrium. British journal of pharmacology, 2000, Volume: 130, Issue:4 Topics: Animals; Atrial Function; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Atria; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Isoflavones; Isoproterenol; Male; Myocardial Contraction; Phosphorylation; Protein-Tyrosine Kinases; Pyrilamine; Receptors, Histamine H1; Time Factors; Tyrosine; Tyrphostins	2000
Histamine H1 receptors in the ventromedial hypothalamus mediate the anorectic action of the pancreatic hormone amylin. Peptides, 2003, Volume: 24, Issue:1 Topics: Amyloid; Animals; Chlorpheniramine; Histamine H1 Antagonists; Islet Amyloid Polypeptide; Male; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Ventromedial Hypothalamic Nucleus	2003
Evaluation of a combination of pheniraminemaleate, pyrilamine maleate, and propanolamine hydrochloride (triaminic) as a diuretic agent. Antibiotic medicine & clinical therapy (New York, NY), 1960, Volume: 7 Topics: Anti-Allergic Agents; Chlorpheniramine; Diuretics; Histamine H1 Antagonists; Humans; Kidney; Propanolamines; Pyrilamine	1960
Evaluation of rynatan. Eye, ear, nose & throat monthly, 1959, Volume: 38 Topics: Anti-Allergic Agents; Chlorpheniramine; Drug Combinations; Histamine H1 Antagonists; Nose Diseases; Phenylephrine; Pyrilamine; Sympathomimetics	1959
Evaluation of a long-acting oral antihistaminic decongestant (rynatan) for nasal allergies. Acta medica Italica di medicina tropicale e subtropicale e di gastroenterologia, 1961, Volume: 16 Topics: Chlorpheniramine; Drug Combinations; Histamine H1 Antagonists; Humans; Nasal Decongestants; Phenylephrine; Pyrilamine; Respiratory Hypersensitivity; Rhinitis, Allergic, Seasonal	1961
Localized expression of histamine H1 receptors in syncytiotrophoblast cells of human placenta. Journal of pharmacological sciences, 2006, Volume: 102, Issue:3 Topics: Adult; Animals; Blotting, Western; Chlorpheniramine; CHO Cells; Chorionic Gonadotropin; Chorionic Villi; Cricetinae; Female; Histamine H1 Antagonists; Humans; Immunohistochemistry; In Vitro Techniques; Placenta; Pregnancy; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Stereoisomerism; Trophoblasts	2006
Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig. British journal of pharmacology, 2007, Volume: 151, Issue:7 Topics: Administration, Oral; Animals; Anti-Allergic Agents; Blood-Brain Barrier; Brain; Cerebellum; Cetirizine; Chlorpheniramine; Chromatography, Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Half-Life; Histamine H1 Antagonists, Non-Sedating; Ileum; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Pyrilamine; Receptors, Histamine H1; Tandem Mass Spectrometry; Time Factors; Tritium	2007
Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom. European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3 Topics: Animals; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Edema; Histamine Antagonists; Histamine Release; Hyperalgesia; Inflammation; Mast Cells; Pain; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Scorpions; Spinal Cord; Time Factors	2007
Simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography. Talanta, 2009, May-15, Volume: 78, Issue:3 Topics: Antitussive Agents; Calibration; Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Expectorants; Guaifenesin; Pharmaceutical Preparations; Pheniramine; Pseudoephedrine; Pyrilamine; Reproducibility of Results	2009