chlorpheniramine and phenytoin

chlorpheniramine has been researched along with phenytoin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's1 (4.00)18.2507
2000's4 (16.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Caron, G; Ermondi, G1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Gozalbes, R; Pineda-Lucena, A1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fleckenstein, L; Horvitz, RA; Morgan, JP1
Ahmad, S; Houghton, GW; Laidlaw, J; Richens, A1
Román-Franco, AA; Santiago-Delpín, EA; Suárez, A; Vivoni, V1
Geddes, AM; Pugh, RN; Yeoman, WB1
Greengard, P; Quinn, GP; Reid, MB1
Brittain, RT1
Hatch, RC1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Bousvaros, G; Russell, MA1
Holloway, DM1
Lee, CC1
Bartels, E; Rosenberg, P1
Blaisdell, J; Dalton, JT; Goldstein, JA; Kidd, RS; Meyer, MC; Straughn, AB1
SNYDER, CH1

Reviews

1 review(s) available for chlorpheniramine and phenytoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

24 other study(ies) available for chlorpheniramine and phenytoin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Savings from generic prescriptions. A study of 33 pharmacies in Rochester, New York.
    Annals of internal medicine, 1975, Volume: 82, Issue:5

    Topics: Alkanesulfonates; Ampicillin; Chlorpheniramine; Costs and Cost Analysis; Dextropropoxyphene; Drug Prescriptions; Erythromycin; Estrogens, Conjugated (USP); Fees, Pharmaceutical; Methenamine; New York; Octanols; Papaverine; Penicillin V; Pentaerythritol Tetranitrate; Pharmacies; Phenytoin; Prescription Fees; Succinates; Sulfisoxazole; Surveys and Questionnaires; Therapeutic Equivalency

1975
Involuntary movements caused by phenytoin intoxication in epileptic patients.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:3

    Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Movement Disorders; Phenobarbital; Phenytoin; Primidone; Thiazines

1975
Protection of organs during experimental ischemia.
    Surgery, gynecology & obstetrics, 1978, Volume: 147, Issue:5

    Topics: Ampicillin; Animals; Chlorpheniramine; Dogs; Hindlimb; Intestine, Small; Ischemia; Methylprednisolone; Models, Biological; Organ Preservation; Phenytoin; Rabbits; Rats; Replantation; Tissue Preservation

1978
Interaction of phenytoin with chlorpheniramine.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:2

    Topics: Adolescent; Chlorpheniramine; Drug Interactions; Female; Humans; Phenytoin

1975
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
    American journal of veterinary research, 1972, Volume: 33, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal

1972
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
Fatal results from diphenylhydantoin administered intravenously.
    JAMA, 1968, Nov-25, Volume: 206, Issue:9

    Topics: Aged; Arrhythmias, Cardiac; Chlorpheniramine; Death, Sudden; Digitalis Glycosides; Dyspnea; Humans; Injections, Intravenous; Male; Myocardial Infarction; Nausea; Phenytoin; Respiratory Tract Diseases

1968
Chlorpheniramine or diphenylhydantoin.
    JAMA, 1969, Mar-17, Volume: 207, Issue:11

    Topics: Adult; Chlorpheniramine; Humans; Male; Phenytoin; Sinusitis

1969
Comparative pharmacologic responses to antihistamines in newborn and young rats.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:2

    Topics: Animals; Animals, Newborn; Brain; Chlorpheniramine; Diphenhydramine; Injections, Subcutaneous; Liver; Phenytoin; Rats

1966
Drug effects on the spontaneous electrical activity of the squid giant axon.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione

1967
Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele.
    Pharmacogenetics, 1999, Volume: 9, Issue:1

    Topics: Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Chlorpheniramine; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Genotype; Glipizide; Homozygote; Humans; Male; Nifedipine; Phenotype; Phenytoin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1999
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
    The Journal of pediatrics, 1965, Volume: 67

    Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy; Epilepsy; Gingival Hyperplasia; Gingivectomy; Hirsutism; Humans; Hypertrichosis; Infant; Infant, Newborn; Intellectual Disability; Phenytoin; Seizures; Syndrome; Toxicology

1965