chlorpheniramine and naloxone

chlorpheniramine has been researched along with naloxone in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.83)18.7374
1990's4 (16.67)18.2507
2000's8 (33.33)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grunstein, MM; Hakim, TS; Michel, RP1
Krowicki, ZK1
Camellini, L; Chiodera, P; Coiro, V; Delsignore, R; Gnudi, A; Ippolito, L; Marchesi, C; Rossi, G; Volpi, R1
Caiazza, A; Chiodera, P; Coiro, V; Ferrari, P; Rossi, G; Salati, G; Volpi, R1
Bernstein, JE; Soltani, K1
Carter, WH; Dewey, WL; Kachur, JF; Tagashira, E1
Corenblum, B; Taylor, PJ1
el Kadi, AO; Sharif, SI1
Adams, DB; Fell, LR1
Chopra, K; Kulkarni, SK; Paul, VN1
Arai, I; Hashimoto, Y; Kurachi, M; Takano, N1
Mojtahedein, A; Tamaddonfard, E; Zanboori, A1
Kamei, C; Nakasone, T; Sugimoto, Y1

Reviews

2 review(s) available for chlorpheniramine and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for chlorpheniramine and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Opiate action in the pulmonary circulation.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:3

    Topics: Animals; Blood Pressure; Cats; Chlorpheniramine; Dogs; Histamine H1 Antagonists; Lung; Morphine; Naloxone; Narcotic Antagonists; Pulmonary Artery; Pulmonary Circulation; Vascular Resistance

1992
Cimetidine does not change the effect of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) on the opiate form of footshock-induced analgesia.
    Life sciences, 1991, Volume: 49, Issue:16

    Topics: Amino Acid Sequence; Analysis of Variance; Animals; Chlorpheniramine; Cimetidine; Electroshock; Male; Molecular Sequence Data; MSH Release-Inhibiting Hormone; Naloxone; Pain; Pain Measurement; Rats; Rats, Inbred Strains

1991
Muscarinic cholinergic and histaminergic H1 and H2 receptors are not involved in the LH response to naloxone in man.
    Hormone research, 1987, Volume: 25, Issue:2

    Topics: Adult; Chlorpheniramine; Cimetidine; Humans; Luteinizing Hormone; Male; Naloxone; Pirenzepine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Muscarinic

1987
Histaminergic H1 and H2 receptors do not mediate cortisol release in response to naloxone in normal men.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1984, Volume: 38, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Chlorpheniramine; Cimetidine; Humans; Hydrocortisone; Male; Naloxone; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Time Factors

1984
Alcohol-induced rosacea flushing blocked by naloxone.
    The British journal of dermatology, 1982, Volume: 107, Issue:1

    Topics: Adult; Alcoholic Beverages; Chlorpheniramine; Double-Blind Method; Face; Female; Humans; Male; Middle Aged; Naloxone; Rosacea; Skin; Skin Temperature; Vasodilation

1982
Potentiation of narcotic-induced antinociception by tripelennamine in morphine-tolerant and drug-naive mice.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1

    Topics: Analgesia; Animals; Chlorpheniramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Male; Mice; Morphine; Naloxone; Pentazocine; Tripelennamine

1984
Mechanisms of control of prolactin release in response to apprehension stress and anesthesia-surgery stress.
    Fertility and sterility, 1981, Volume: 36, Issue:6

    Topics: Adult; Anesthesia; Anxiety; Chlorpheniramine; Cyproheptadine; Female; Humans; Naloxone; Pimozide; Prolactin; Stress, Physiological; Stress, Psychological; Surgical Procedures, Operative

1981
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypothermia; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Norepinephrine; Oxidopamine; Substance Withdrawal Syndrome; Sympatholytics; Weight Loss

1996
The effect of infection with the abomasal nematode, Haemonchus contortus, on the avoidance behaviour of sheep in a motivational-choice test.
    International journal for parasitology, 1997, Volume: 27, Issue:6

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Dexamethasone; Female; Haemonchiasis; Haemonchus; Immunosuppressive Agents; Male; Naloxone; Sheep; Sheep Diseases

1997
Histaminergic modulation of stress-induced analgesia and cognitive dysfunction.
    Methods and findings in experimental and clinical pharmacology, 2002, Volume: 24, Issue:7

    Topics: Analgesia; Analgesics; Animals; Chlorpheniramine; Cimetidine; Cognition Disorders; Female; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Histidine; Male; Maze Learning; Memory Disorders; Mice; Naloxone; Narcotic Antagonists; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stress, Physiological

2002
Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Alprostadil; Animals; Antipruritics; Behavior, Animal; Capsaicin; Chlorpheniramine; Cyproheptadine; Dermatitis, Atopic; Dexamethasone; Dibucaine; Male; Mice; Mice, Inbred Strains; Naloxone; Pinacidil; Pruritus; Tacrolimus; Theophylline; Time Factors

2004
Effects of chlorpheniramine and ranitidine on the visceral nociception induced by acetic acid in rats: role of opioid system.
    Pakistan journal of biological sciences : PJBS, 2008, Oct-15, Volume: 11, Issue:20

    Topics: Acetic Acid; Analgesics; Animals; Chlorpheniramine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Opioid Peptides; Pain Measurement; Ranitidine; Rats; Rats, Wistar

2008
The interaction between histamine H1 receptor and μ- opioid receptor in scratching behavior in ICR mice.
    European journal of pharmacology, 2016, Apr-15, Volume: 777

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Histamine; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Protein Binding; Pruritus; Receptors, Histamine H1; Receptors, Opioid, mu

2016