chlorpheniramine and morphine

chlorpheniramine has been researched along with morphine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199012 (36.36)18.7374
1990's3 (9.09)18.2507
2000's12 (36.36)29.6817
2010's5 (15.15)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Nagashima, R; Nishikawa, T; Tobita, M1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buyniski, JP; Cavanagh, RL; Schurig, JE1
Grunstein, MM; Hakim, TS; Michel, RP1
Masukawa, Y; Misawa, M; Suzuki, T2
Hanig, JP; Hui, FW; Sun, CL1
Castellano, C; D'Amato, FR; Sansone, M1
D'Udine, B; Renzi, P; Sansone, M; Vetulani, J1
Greengard, P; Quinn, GP; Reid, MB1
Arrigoni, E; Benzi, G; Bermudez, E1
Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N1
Hatch, RC1
Saarnivaara, L1
Carter, WH; Dewey, WL; Kachur, JF; Tagashira, E1
Hayashi, T; Kuramasu, A; Mobarakeh, JI; Okuyama, K; Orito, T; Sakurada, S; Sakurada, T; Watanabe, T; Yanai, K1
ERICKSON, RW; GREEN, H1
Rupasinghe, M; Samieh-Tucker, A1
Mojtahedein, A; Tamaddonfard, E; Zanboori, A1
Kamei, C; Nakasone, T; Sugimoto, Y1
Chang, CL; Chang, YJ; Chen, TY; Chyueh, SC; Lai, PJ; Yen, YT1

Reviews

2 review(s) available for chlorpheniramine and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

31 other study(ies) available for chlorpheniramine and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effect of butorphanol and morphine on pulmonary mechanics, arterial blood pressure and venous plasma histamine in the anesthetized dog.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 233, Issue:2

    Topics: Airway Resistance; Animals; Blood Pressure; Chlorpheniramine; Dogs; Female; Histamine; Lung; Male; Morphinans; Morphine; Time Factors

1978
Opiate action in the pulmonary circulation.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:3

    Topics: Animals; Blood Pressure; Cats; Chlorpheniramine; Dogs; Histamine H1 Antagonists; Lung; Morphine; Naloxone; Narcotic Antagonists; Pulmonary Artery; Pulmonary Circulation; Vascular Resistance

1992
Drug interactions in the reinforcing effects of over-the-counter cough syrups.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Antitussive Agents; Benzazepines; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Substance-Related Disorders

1990
Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice.
    Neuropharmacology, 1985, Volume: 24, Issue:1

    Topics: Analgesics; Animals; Chlorpheniramine; Cyclizine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Male; Mice; Morphine; Phenothiazines; Pyrilamine

1985
Enhancement of morphine-induced hyperactivity by antihistaminic drugs in mice.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2

    Topics: Animals; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Tripelennamine

1986
Antihistaminics enhance morphine-, but not amphetamine- and scopolamine-induced hyperactivity in mice.
    Psychopharmacology, 1987, Volume: 93, Issue:2

    Topics: Animals; Chlorpheniramine; Dextroamphetamine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Hyperkinesis; Male; Mice; Morphine; Scopolamine; Tripelennamine

1987
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Action of antibiotics on respiratory tract. I. Ampicillin.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:4

    Topics: Acetylcholine; Amino Alcohols; Ampicillin; Animals; Atropine; Barium; Bronchi; Bronchial Spasm; Chlorpheniramine; Cyproheptadine; Dibenzylchlorethamine; Dogs; Epinephrine; Female; Hexamethonium Compounds; Histamine H1 Antagonists; In Vitro Techniques; Isoproterenol; Male; Morphine; Muscle Contraction; Muscle, Smooth; Phenethylamines; Respiration; Vagotomy

1970
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays

1971
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
    American journal of veterinary research, 1972, Volume: 33, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal

1972
Effect of 5-hydroxytryptamine on morphine analgesia in rabbits.
    Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2

    Topics: Analgesia; Animals; Blood Pressure; Blood-Brain Barrier; Cerebrospinal Fluid; Chlorpheniramine; Cyproheptadine; Dental Pulp Test; Drug Synergism; Electrodes; Morphine; Rabbits; Serotonin; Serotonin Antagonists

1969
Potentiation of narcotic-induced antinociception by tripelennamine in morphine-tolerant and drug-naive mice.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:1

    Topics: Analgesia; Animals; Chlorpheniramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Male; Mice; Morphine; Naloxone; Pentazocine; Tripelennamine

1984
Differential modification of the rewarding effects of methamphetamine and cocaine by opioids and antihistamines.
    Psychopharmacology, 1993, Volume: 111, Issue:2

    Topics: Animals; Appetite; Chlorpheniramine; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Histamine Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward

1993
Enhanced antinociception by intrathecally-administered morphine in histamine H1 receptor gene knockout mice.
    Neuropharmacology, 2002, Volume: 42, Issue:8

    Topics: Analgesics; Animals; Chlorpheniramine; Dose-Response Relationship, Drug; Drug Synergism; Hot Temperature; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Morphine; Pain Measurement; Physical Stimulation; Receptors, Histamine H1; Stimulation, Chemical

2002
EFFECT OF SOME DRUGS UPON RAT BRAIN HISTAMINE CONTENT.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Antidepressive Agents; Aspirin; Benactyzine; Brain; Brain Chemistry; Chemistry Techniques, Analytical; Chlorpheniramine; Dextroamphetamine; Diphenhydramine; Fluorescence; Fluorometry; Histamine; Morphine; Pharmacology; Rats; Research; Tranquilizing Agents; Tranylcypromine; Tripelennamine

1964
Anaesthesia for caesarean section in a patient with acute generalised pustular psoriasis.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anti-Allergic Agents; Anti-Bacterial Agents; Anti-Infective Agents; Cesarean Section; Chlorpheniramine; Female; Gentamicins; Humans; Metronidazole; Morphine; Neuromuscular Depolarizing Agents; Pregnancy; Psoriasis; Succinylcholine; Thiopental

2007
Effects of chlorpheniramine and ranitidine on the visceral nociception induced by acetic acid in rats: role of opioid system.
    Pakistan journal of biological sciences : PJBS, 2008, Oct-15, Volume: 11, Issue:20

    Topics: Acetic Acid; Analgesics; Animals; Chlorpheniramine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Opioid Peptides; Pain Measurement; Ranitidine; Rats; Rats, Wistar

2008
The interaction between histamine H1 receptor and μ- opioid receptor in scratching behavior in ICR mice.
    European journal of pharmacology, 2016, Apr-15, Volume: 777

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Histamine; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Protein Binding; Pruritus; Receptors, Histamine H1; Receptors, Opioid, mu

2016
A Study of Opiate, Opiate Metabolites and Antihistamines in Urine after Consumption of Cold Syrups by LC-MS/MS.
    Molecules (Basel, Switzerland), 2020, Feb-21, Volume: 25, Issue:4

    Topics: Adult; Analgesics, Opioid; Chlorpheniramine; Codeine; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Histamine Antagonists; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Opiate Alkaloids; Pyridines; Young Adult

2020