chlorpheniramine and indomethacin

chlorpheniramine has been researched along with indomethacin in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199029 (41.43)18.7374
1990's18 (25.71)18.2507
2000's10 (14.29)29.6817
2010's13 (18.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Beaumont, K; Di, L; Maurer, TS; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barnett, DB; Bourne, HR; Chesrown, SE; Gold, WM; Melmon, KL; Nisam, M; Reed, BR; Zbinden, AF1
Brink, C; Gorenne, I; Labat, C; Norel, X; Ortiz, JL; Verley, J2
Toda, N; Yamazaki, M1
Cunningham, FM; Foster, AP; Lees, P1
Adkinson, NF; Kleeberger, SR; Kolbe, J; Peters, SP; Spannhake, EW1
Abraham, WM; Garrido, R; Stevenson, JS1
Aursudkij, B; Barnes, PJ; Chung, KF; Evans, TW; Rogers, DF1
Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S1
Leff, AR; Munoz, NM; Popovich, KJ; Shioya, T; Stimler-Gerard, NP; White, SR1
Albertine, KH; Staub, NC1
Accomando, RC; Cervoni, P; Chan, PS; Ronsberg, MA; Scully, PA1
Hand, JM; Lewis, AJ; Schwalm, SF1
Lahti, A; Maibach, HI; McDonald, DM; Tammi, R1
Patterson, R; Rubin, AH; Smith, LJ1
Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K1
Bailenger, J; Lacassie, A1
Toda, N1
Fukuhara, T; Shibasaki, Y; Shibata, Y; Yamasaki, K1
Clay, TP; Miller, P; Stead, H1
Müller-Schweinitzer, E1
Ignarro, LJ1
Feely, J; Wood, AJ1
Belis, JA; Galie, JR; Longhurst, PA; O'Donnell, JP; Westfall, DP1
Hammerbeck, DM; Swingle, KF1
Bromberger-Barnea, B; Dannenberg, AM; Gertner, A; Menkes, H; Traystman, R1
Konishi, M; Miyazaki, M; Toda, N1
Abraham, WM; King, MM; Oliver, W; Wanner, A; Yerger, L1
Ahmed, T; Frank, BL; Oliver, W; Robinson, MJ; Wanner, A1
Jaenicke, KF; Momtaz, K; Morison, WL; Parrish, JA; Shea, C1
Coutts, A; Davies, M; Greaves, M; Misch, K1
Bayoumi, AH; Marks, R1
Bolser, DC; Chapman, RW; DeGennaro, FC; Hey, JA; O'Reilly, S1
Lloret, S; Moreno, JJ1
Murai, A; Nakahata, N; Nakamura, H; Ohizumi, Y; Rho, MC1
Emery, DL; McClure, SJ1
Brown, DR; Hammerbeck, DM1
Häglund, BO; Sundelöf, LO; Upadrashta, SM1
Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Terada, A; Yamaguchi, T1
Enzan, K; Mitchell, MD; Schultz, E; Staub, NC; Stavros, F; Wang, Y1
Kani, K; Kitamura, Y; Okamura, T; Toda, N1
Horie, T; Koyama, S; Morimoto, R; Tanaka, A1
Fu, LW; Longhurst, JC; Pan, HL1
Furuyama, S; Nakao, S; Ogata, Y; Sugiya, H; Suzuki, T; Tsunoda, S1
Bautista, E; Becker, A; Chrusch, C; Duke, K; Kepron, W; Mink, SN; Sharma, S; Unruh, H1
Fu, C; Jiang, X; Zhao, L1
Chen, IM; Cheng, CY; Lin, CH; Lin, MS; Lin, PR; Lin, YH; Tsai, MC1
Alviña, K; Boric, MP; Figueroa, XF; Garcés, G; Martínez, AD; Rosemblatt, M; Sáez, JC1
McGinity, JW; Mehta, KA; Zhu, Y1
Boskabady, MH; Jafari, Z; Rahbardar, MG1
Boskabady, MH; Gholamnezhad, Z; Sadeghnia, HR; Tabanfar, H1
Berania, JE; Chai, CC; Chan, SY; Gokhale, R; Khong, YM; Liu, X; Low, AQ; Parmentier, J; Tun, TY1
Chan, SY; Foo, WC; Gokhale, R; Khong, YM; Widjaja, E1

Reviews

2 review(s) available for chlorpheniramine and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

68 other study(ies) available for chlorpheniramine and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Volume of Distribution in Drug Design.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Drug Design; Half-Life; Pharmacokinetics

2015
Cyclic AMP and cyclic GMP in canine peripheral lung: regulation in vivo.
    The American review of respiratory disease, 1978, Volume: 118, Issue:4

    Topics: Airway Resistance; Animals; Chlorpheniramine; Cyclic AMP; Cyclic GMP; Dogs; Indomethacin; Lung; Lung Compliance; Propranolol; Prostaglandin-Endoperoxide Synthases; Respiration; Respiration, Artificial; Sympathectomy; Vagotomy

1978
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pulmonary Artery; Receptors, Histamine; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Thiourea

1992
[Mechanisms of histamine-induced relaxation in isolated dog mesenteric arteries and veins].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:1

    Topics: Animals; Chlorpheniramine; Cimetidine; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; Histamine; Histamine Antagonists; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Histamine H1; Receptors, Histamine H2

1992
Inflammatory effects of platelet activating factor (PAF) in equine skin.
    Equine veterinary journal, 1992, Volume: 24, Issue:3

    Topics: Animals; Capillary Permeability; Chlorpheniramine; Dermatitis; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Horse Diseases; Horses; Indomethacin; Injections, Intradermal; Leukocyte Count; Neutrophils; Platelet Activating Factor; Regional Blood Flow; Skin; Skin Temperature

1992
Central role of cyclooxygenase in the response of canine peripheral airways to antigen.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:4

    Topics: Aerosols; Animals; Antigens; Antigens, Helminth; Ascaris; Chlorpheniramine; Dogs; Histamine Release; Indomethacin; Lung; Male; Ovalbumin; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins D; Therapeutic Irrigation

1986
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles

1989
Inflammatory mediators involved in antigen-induced airway microvascular leakage in guinea pigs.
    The American review of respiratory disease, 1988, Volume: 138, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Bronchi; Capillary Permeability; Chlorpheniramine; Chromones; Cimetidine; Guinea Pigs; Immunization; Indomethacin; Inflammation; Lactones; Larynx; Male; Nasal Mucosa; Nedocromil; Ovalbumin; Plant Extracts; Pyrazoles; Quinolones; Respiratory System; Trachea; Urinary Bladder

1988
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin

1985
Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:2

    Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Platelet Activating Factor; Reference Values; Trachea

1987
Vascular tracers alter hemodynamics and airway pressure in anesthetized sheep.
    Microvascular research, 1986, Volume: 32, Issue:3

    Topics: Animals; Blood Pressure; Capillary Permeability; Chlorpheniramine; Gold Colloid, Radioactive; Hemodynamics; Indoles; Indomethacin; Lung; Microscopy, Electron; Organometallic Compounds; Pressure; Pulmonary Ventilation; Sheep

1986
Mechanism of action of a new prostaglandin antihypertensive, viprostol [CL 115 347; (dl)-15-deoxy-16-hydroxy-16(alpha/beta)-vinyl-prostaglandin E2 methyl ester]: (I). Vasodilation.
    Journal of hypertension, 1986, Volume: 4, Issue:6

    Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Chlorpheniramine; Cimetidine; Dinoprostone; Dogs; Drug Interactions; Female; Heart Rate; Indomethacin; Male; Nephrectomy; Propranolol; Prostaglandins E; Prostaglandins E, Synthetic; Rabbits; Rats; Rats, Inbred SHR; Receptors, Adrenergic, beta; Regional Blood Flow; Vasodilation

1986
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
    International archives of allergy and applied immunology, 1986, Volume: 79, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Catechols; Chlorpheniramine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea

1986
Pharmacological studies on nonimmunologic contact urticaria in guinea pigs.
    Archives of dermatological research, 1986, Volume: 279, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Capsaicin; Chlorpheniramine; Dermatitis, Contact; Dexamethasone; Female; Guinea Pigs; Indomethacin; Male; Premedication; Pyrazoles; Ranitidine; Urticaria

1986
Mechanism of platelet activating factor-induced bronchoconstriction in humans.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Dose-Response Relationship, Drug; Humans; Indomethacin; Platelet Activating Factor; Respiratory Function Tests

1988
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
    European journal of pharmacology, 1988, Apr-13, Volume: 148, Issue:3

    Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis

1988
[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation].
    Annales de parasitologie humaine et comparee, 1986, Volume: 61, Issue:6

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Indomethacin; Inflammation; Male; Nematode Infections; Promethazine; Rats; Rats, Inbred Strains; Sodium Salicylate; Stereoisomerism; Strongyloides; Strongyloidiasis

1986
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Indomethacin; Macaca; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Quinones; Vasodilation

1986
The nature of the pain reaction associated with orthodontic tooth movement.
    Nihon Kyosei Shika Gakkai zasshi = The journal of Japan Orthodontic Society, 1985, Volume: 44, Issue:2

    Topics: Bromelains; Chlorpheniramine; Humans; Indomethacin; Orthodontic Appliances; Pain; Periodontium; Stress, Mechanical; Tooth Movement Techniques

1985
A lung perfusion technique for the detection of antigenic intrapulmonary bronchoconstriction and its mediation.
    Journal of pharmacological methods, 1985, Volume: 14, Issue:3

    Topics: Animals; Antigens; Bronchi; Chlorpheniramine; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Perfusion; Pressure; Pyrazoles; Pyrilamine; Respiratory Hypersensitivity

1985
Studies on the peripheral mode of action of dihydroergotamine in human and canine veins.
    European journal of pharmacology, 1974, Volume: 27, Issue:2

    Topics: Animals; Atropine; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Ergotamine; Femoral Vein; Humans; In Vitro Techniques; Indomethacin; Methysergide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Saphenous Vein; Veins

1974
Lysosome membrane stabilization in vivo: effects of steroidal and nonsteroidal anti-inflammatory drugs on the integrity of rat liver lysosomes.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Chlorpheniramine; Chlorpromazine; Cyclophosphamide; Dextropropoxyphene; Flufenamic Acid; Glucosidases; Hydrocortisone; In Vitro Techniques; Indomethacin; Kinetics; Liver; Lysosomes; Mefenamic Acid; Membranes; Osmotic Fragility; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats; Steroids; Vitamin A

1972
Effect on apparent liver blood flow of histamine-receptor blockers and inhibition of prostaglandin synthesis.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:1

    Topics: Adult; Chlorpheniramine; Cimetidine; Cyclooxygenase Inhibitors; Histamine H2 Antagonists; Humans; Indocyanine Green; Indomethacin; Liver; Male

1983
A study of the atropine-resistant component of the neurogenic response of the rabbit urinary bladder.
    European journal of pharmacology, 1984, Apr-06, Volume: 99, Issue:4

    Topics: Animals; Atropine; Capsaicin; Chlorpheniramine; Drug Resistance; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Neurotransmitter Agents; Rabbits; Urinary Bladder

1984
Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs.
    International archives of allergy and applied immunology, 1984, Volume: 74, Issue:1

    Topics: Aerosols; Anaphylaxis; Animals; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Guinea Pigs; Hypersensitivity, Immediate; Indomethacin; Lipoxygenase; Male; Premedication; Prostaglandin-Endoperoxide Synthases

1984
Responses of the lung periphery to 1.0 ppm ozone.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 55, Issue:3

    Topics: Animals; Chlorpheniramine; Dogs; Indomethacin; Lung; Male; Nerve Block; Ozone; Parasympathetic Nervous System

1983
Involvement of endogenous prostaglandin I2 in the vascular action of histamine in dogs.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1

    Topics: Animals; Aspirin; Blood Vessels; Chlorpheniramine; Cimetidine; Dogs; Epoprostenol; Female; Histamine; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Tranylcypromine; Vasoconstriction; Vasodilation

1982
Effect of pharmacologic agents on antigen-induced decreases in specific lung conductance in sheep.
    The American review of respiratory disease, 1981, Volume: 124, Issue:5

    Topics: Airway Resistance; Animals; Antigens; Ascaris; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Cromolyn Sodium; Ethers; Indomethacin; Metiamide; Respiratory Hypersensitivity; Sheep

1981
Hypoxic pulmonary vasoconstriction in conscious sheep: role of mast cell degranulation.
    The American review of respiratory disease, 1982, Volume: 126, Issue:2

    Topics: Animals; Chlorpheniramine; Cromolyn Sodium; Cytoplasmic Granules; Female; Hemodynamics; Hypoxia; Indomethacin; Lung; Mast Cells; Metiamide; Sheep; Vasoconstriction

1982
Solar urticaria: treatment with PUVA and mediator inhibitors.
    The British journal of dermatology, 1982, Volume: 106, Issue:5

    Topics: Adolescent; Adult; Chlorpheniramine; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Photochemotherapy; PUVA Therapy; Sunlight; Urticaria

1982
Pharmacological studies of anthralin erythema.
    The British journal of dermatology, 1981, Volume: 105 Suppl 20

    Topics: Anthracenes; Anthralin; Aspirin; Betamethasone Valerate; Chlorpheniramine; Erythema; Female; Humans; Indomethacin; Male; Psoriasis; Scopolamine; Skin

1981
Transepidermal elimination: studies with an animal model.
    British journal of experimental pathology, 1980, Volume: 61, Issue:6

    Topics: Animals; Charcoal; Chlorpheniramine; Cimetidine; Epidermal Cells; Epidermis; Guinea Pigs; Indomethacin; Injections, Intradermal; Models, Biological

1980
Pharmacological studies of allergic cough in the guinea pig.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsaicin; Chlorpheniramine; Cimetidine; Codeine; Cough; Drug Hypersensitivity; Guinea Pigs; Hexamethonium; Histamine Antagonists; Indomethacin; Injections, Subcutaneous; Ipratropium; Loratadine; Male; Ovalbumin; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2

1995
Effect of nonapeptide fragments of uteroglobin and lipocortin I on oedema and mast cell degranulation.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Animals; Annexin A1; Aristolochic Acids; Carrageenan; Cell Degranulation; Chlorpheniramine; Dexamethasone; Disease Models, Animal; Edema; Elapid Venoms; Elapidae; Histamine Release; Indomethacin; Inflammation; Injections, Intradermal; Male; Mast Cells; Peptide Fragments; Phenanthrenes; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Uteroglobin

1994
Activation of rabbit platelets by Ca2+ influx and thromboxane A2 release in an external Ca(2+)-dependent manner by zooxanthellatoxin-A, a novel polyol.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Alkaloids; Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Chlorpheniramine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Genistein; Histamine H1 Antagonists; Hydrazines; Imidazoles; Indomethacin; Isoflavones; Male; Marine Toxins; Methysergide; Platelet Aggregation Inhibitors; Polyenes; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Serotonin Antagonists; Staurosporine; Tetrodotoxin; Thromboxane A2; Thromboxane B2

1995
Studies on the inhibition of rejection of Trichostrongylus colubriformis larvae from immune sheep.
    International journal for parasitology, 1995, Volume: 25, Issue:6

    Topics: Animals; Azepines; Chlorpheniramine; Cyclosporine; Dexamethasone; Indomethacin; Larva; Piroxicam; Rejection, Psychology; Sheep; Sheep Diseases; Theophylline; Triazoles; Trichostrongylosis; Trichostrongylus

1995
Response to anti-human IgE in human pulmonary arteries. Regulation by endothelium.
    The American review of respiratory disease, 1993, Volume: 147, Issue:4

    Topics: Arginine; Chlorpheniramine; Endothelium, Vascular; Epoprostenol; Histamine Release; Humans; Immunoenzyme Techniques; Immunoglobulin E; In Vitro Techniques; Indomethacin; Muscle Relaxation; Nitroarginine; Pulmonary Artery

1993
Selective hyperresponsiveness to ovalbumin-induced epithelial transport in inflamed guinea pig distal colon.
    Inflammation, 1993, Volume: 17, Issue:6

    Topics: Animals; Antigens; Chlorpheniramine; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Ion Transport; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin

1993
Diffusion and concentration profiles of drugs in gels.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:11

    Topics: Acetaminophen; Chlorpheniramine; Diffusion; Gels; Humans; Ibuprofen; Indomethacin; Pharmacokinetics; Temperature; Theophylline

1993
Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Chlorpheniramine; Disease Models, Animal; Guinea Pigs; Indomethacin; Male; Methacrylates; Ovalbumin; Propranolol; Prostaglandin Endoperoxides, Synthetic; SRS-A; Thiophenes; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents

1993
Pulmonary hypertensive response to rabbit blood components in goats: role of thromboxane.
    The American review of respiratory disease, 1993, Volume: 147, Issue:4

    Topics: Animals; Blood Physiological Phenomena; Chlorpheniramine; Female; Goats; Hemodynamics; Hypertension, Pulmonary; Indomethacin; Isoproterenol; Male; Nitrendipine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Thromboxane B2

1993
Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Summer, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Arteries; Chlorpheniramine; Cimetidine; Dinoprost; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Receptors, Histamine H1; Receptors, Histamine H2; Retinal Artery; Substance P; Temporal Arteries

1995
[Hypertonic saline induced bronchoconstriction in sensitized rabbits].
    Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34, Issue:5

    Topics: Animals; Asthma; Atropine; Bronchoconstriction; Chlorpheniramine; Cholinergic Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Indomethacin; Male; Rabbits; Saline Solution, Hypertonic; Vagus Nerve

1996
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; Duodenum; Female; Gallbladder; Histamine; Histamine H1 Antagonists; Indomethacin; Ischemia; Male; Methylhistamines; Nerve Fibers; Neural Conduction; Pancreas; Pyrilamine; Receptors, Histamine H1

1997
Involvement of prostaglandins in histamine H1 receptor-operated Ca2+ entry in human gingival fibroblasts.
    Life sciences, 1999, Volume: 64, Issue:4

    Topics: Aspirin; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Chlorpheniramine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Fura-2; Gingiva; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Indomethacin; Prostaglandins; Receptors, Histamine H1; Thapsigargin

1999
Histamine H3 receptor blockade improves cardiac function in canine anaphylaxis.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4

    Topics: Anaphylaxis; Animals; Chlorpheniramine; Cyclooxygenase Inhibitors; Dogs; Hemodynamics; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Indoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Myocardial Contraction; Piperidines; Prostaglandins; Quinolines; Ranitidine; Receptors, Histamine H3; Stroke Volume; Ventricular Function, Left

1999
[Sensitivity of cationic polymer Eudragit RL to electrolytes and its effect on drug release from Eudragit RL matrix].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:7

    Topics: Chlorpheniramine; Delayed-Action Preparations; Electrolytes; Indomethacin; Microspheres; Nifedipine; Polymers; Polymethacrylic Acids

1998
A new isoquinolinone derivative with noble vasorelaxation activity.
    Pharmacology, 2003, Volume: 67, Issue:4

    Topics: Acetylcholine; Adrenergic Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Atropine; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Isoquinolines; Magnetic Resonance Spectroscopy; Male; Muscarinic Antagonists; Phenylephrine; Propranolol; Pyridines; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Yohimbine

2003
Histamine reduces gap junctional communication of human tonsil high endothelial cells in culture.
    Microvascular research, 2004, Volume: 68, Issue:3

    Topics: Cells, Cultured; Chlorpheniramine; Coloring Agents; Connexin 43; Cyclic AMP; Cyclooxygenase Inhibitors; Cytoskeleton; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Gap Junctions; Histamine; Humans; Immunoblotting; Indoles; Indomethacin; Inflammation; Ionophores; Maleimides; Microscopy, Fluorescence; Palatine Tonsil; Phalloidine; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors

2004
Influence of plasticizer level on the drug release from sustained release film coated and hot-melt extruded dosage forms.
    Pharmaceutical development and technology, 2006, Volume: 11, Issue:3

    Topics: Calorimetry, Differential Scanning; Chlorpheniramine; Chromatography, High Pressure Liquid; Citrates; Delayed-Action Preparations; Diltiazem; Drug Stability; Hot Temperature; Indomethacin; Microscopy, Electron, Scanning; Particle Size; Pharmaceutical Preparations; Plasticizers; Polymethacrylic Acids; Solubility; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Thermogravimetry; Water; X-Ray Diffraction

2006
The effect of safranal on histamine (H(1)) receptors of guinea pig tracheal chains.
    Fitoterapia, 2011, Volume: 82, Issue:2

    Topics: Animals; Atropine; Chlorpheniramine; Crocus; Cyclohexenes; Dose-Response Relationship, Drug; Flowers; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indomethacin; Plant Extracts; Propranolol; Receptors, Adrenergic, beta; Receptors, Histamine H1; Receptors, Muscarinic; Terpenes; Trachea

2011
Inhibitory effect of Zataria multiflora Boiss and carvacrol on histamine (H(1) ) receptors of guinea-pig tracheal chains.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:5

    Topics: Animals; Atropine; Chlorpheniramine; Cymenes; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indomethacin; Lamiaceae; Male; Monoterpenes; Plant Extracts; Propranolol; Receptors, Histamine H1; Trachea

2012
Effect of type and ratio of solubilising polymer on characteristics of hot-melt extruded orodispersible films.
    International journal of pharmaceutics, 2013, Oct-15, Volume: 455, Issue:1-2

    Topics: Administration, Oral; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Drug Delivery Systems; Hot Temperature; Indomethacin; Polyethylene Glycols; Polyvinyls; Povidone; Solubility; Technology, Pharmaceutical

2013
Application of miniaturized near-infrared spectroscopy for quality control of extemporaneous orodispersible films.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-20, Volume: 150

    Topics: Administration, Oral; Calibration; Chlorpheniramine; Dexamethasone; Dosage Forms; Drug Compounding; Indomethacin; Limit of Detection; Miniaturization; Nitrofurantoin; Ondansetron; Pharmaceutical Preparations; Principal Component Analysis; Quality Control; Reference Standards; Reproducibility of Results; Spectroscopy, Near-Infrared; Technology, Pharmaceutical

2018