chlorpheniramine and ibuprofen

chlorpheniramine has been researched along with ibuprofen in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's6 (20.00)18.2507
2000's13 (43.33)29.6817
2010's9 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Court, H; Streete, P; Volans, GN1
Bodmeier, R; Paeratakul, O1
Häglund, BO; Sundelöf, LO; Upadrashta, SM1
Box, SA; Lee, MR1
Haginaka, J; Takehira, H1
McGinity, JW; Wu, C1
Haginaka, J; Matsunaga, H; Okazaki, Y1
Gwaltney, JM; Hendley, JO; Patrie, JT; Winther, B1
Bytautiene, E; Garfield, RE; Maul, H; Saade, GR; Vedernikov, Y1
Bytautiene, E; Garfield, RE; Romero, R; Saade, GR; Vedernikov, YP1
Berlin, RG; Berman, GD; Butkerait, P; Cooper, SA; Corren, J; Doyle, G; Meltzer, EO; Pedinoff, AJ; Waksman, JA; Wason, S1
Le Brun, V; Siepmann, F; Siepmann, J1
Qiu, ZY; Yin, SF1
Ali, O; Hegazy, M; Moustafa, AA; Salem, H1
Jadhav, N; Nadaf, S; Nnamani, P1

Reviews

2 review(s) available for chlorpheniramine and ibuprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for chlorpheniramine and ibuprofen

ArticleYear
Combined antiviral-antimediator treatment for the common cold.
    The Journal of infectious diseases, 2002, Jul-15, Volume: 186, Issue:2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Common Cold; Cough; Double-Blind Method; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Ibuprofen; Interferon-alpha; Male; Middle Aged; Nasal Mucosa; Nasal Obstruction; Pharyngitis; Rhinovirus; Sneezing

2002
Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:5

    Topics: Adult; Chlorpheniramine; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Humans; Ibuprofen; Male; Middle Aged; Rhinitis, Allergic, Seasonal

2004

Other Studies

26 other study(ies) available for chlorpheniramine and ibuprofen

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Acute poisoning with ibuprofen.
    Human toxicology, 1983, Volume: 2, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpheniramine; Diazepam; Female; Humans; Ibuprofen; Male; Middle Aged

1983
Mechanical properties of dry and wet cellulosic and acrylic films prepared from aqueous colloidal polymer dispersions used in the coating of solid dosage forms.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Acrylates; Acrylic Resins; Cellulose; Chlorpheniramine; Colloids; Diffusion; Dosage Forms; Drug Compounding; Excipients; Hardness Tests; Ibuprofen; Permeability; Plasticizers

1994
Diffusion and concentration profiles of drugs in gels.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:11

    Topics: Acetaminophen; Chlorpheniramine; Diffusion; Gels; Humans; Ibuprofen; Indomethacin; Pharmacokinetics; Temperature; Theophylline

1993
A systemic reaction following exposure to a pyrethroid insecticide.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: Abdominal Pain; Agricultural Workers' Diseases; Analgesics, Opioid; Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Cefuroxime; Cephalosporins; Chlorpheniramine; Erythromycin; Humans; Ibuprofen; Insecticides; Male; Meperidine; Middle Aged; Occupational Exposure; Pruritus; Pyrethrins; Sheep; Urticaria; Vomiting

1996
Separation of enantiomers on a chiral stationary phase based on ovoglycoprotein. II. Comparison of chiral recognition properties with crude ovomucoid.
    Journal of chromatography. A, 1997, Aug-15, Volume: 777, Issue:2

    Topics: Animals; Benzoin; Chickens; Chlorpheniramine; Chromatography, High Pressure Liquid; Egg White; Gels; Glycoproteins; Ibuprofen; Indicators and Reagents; Models, Chemical; Ovomucin; Protein Binding; Silicon Dioxide; Stereoisomerism

1997
Non-traditional plasticization of polymeric films.
    International journal of pharmaceutics, 1999, Jan-15, Volume: 177, Issue:1

    Topics: Chlorpheniramine; Ibuprofen; Parabens; Plasticizers; Polymers; Tablets; Tensile Strength; Theophylline; Thermal Conductivity

1999
Separation of enantiomers on a chiral stationary phase based on ovoglycoprotein. V. Influence of immobilization method on chiral resolution.
    Journal of chromatography. A, 1999, Apr-30, Volume: 840, Issue:2

    Topics: Benzoin; Chlorpheniramine; Chromatography, High Pressure Liquid; Egg White; Glycopeptides; Ibuprofen; Indicators and Reagents; Silica Gel; Silicon Dioxide; Solutions; Stereoisomerism

1999
Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:6

    Topics: Animals; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Histamine; Ibuprofen; Mast Cells; Oligopeptides; p-Methoxy-N-methylphenethylamine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Thrombin; Uterine Contraction

2003
Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:5

    Topics: Cell Degranulation; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Ibuprofen; Linoleic Acids; Longitudinal Studies; Mast Cells; Myometrium; p-Methoxy-N-methylphenethylamine; Pregnancy; Uterine Contraction

2004
Drugs acting as plasticizers in polymeric systems: a quantitative treatment.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Oct-27, Volume: 115, Issue:3

    Topics: Chemistry, Pharmaceutical; Chlorpheniramine; Delayed-Action Preparations; Diffusion; Drug Carriers; Ibuprofen; Kinetics; Metoprolol; Models, Chemical; Plasticizers; Polymethacrylic Acids; Solubility; Tensile Strength; Transition Temperature

2006
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride

2009
[Simultaneous determination of ibuprofen and pseudoephedrin hydrochloride and chlorpheniramine maleate in the compound buluoweimanamin tablets by HPLC].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:7

    Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Ibuprofen; Pseudoephedrine; Tablets

2010
Evaluating the efficiency of spectral resolution of univariate methods manipulating ratio spectra and comparing to multivariate methods: an application to ternary mixture in common cold preparation.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Feb-25, Volume: 137

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Common Cold; Drug Combinations; Histamine H1 Antagonists; Ibuprofen; Least-Squares Analysis; Limit of Detection; Multivariate Analysis; Nasal Decongestants; Pseudoephedrine; Spectrophotometry; Tablets

2015
Evaluation of Prosopis africana Seed Gum as an Extended Release Polymer for Tablet Formulation.
    AAPS PharmSciTech, 2015, Volume: 16, Issue:3

    Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chitosan; Chlorpheniramine; Delayed-Action Preparations; Diclofenac; Drug Carriers; Drug Compounding; Hypromellose Derivatives; Ibuprofen; Plant Gums; Polymers; Polysaccharides, Bacterial; Prosopis; Seeds; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction

2015