chlorpheniramine and fexofenadine

chlorpheniramine has been researched along with fexofenadine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Avdeef, A; Tam, KY1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ido, T; Ito, K; Itoh, M; Iwata, R; Ryu, JH; Sawai, Y; Watanabe, T; Yanai, K1
Gu, X; Silver, NA; Simons, FE; Simons, KJ1
Hasegawa, Y; Hindmarch, I; Ishikawa, K; Kamei, H; Muraoka, I; Nabeshima, T; Noda, Y; Senzaki, K1
Boyle, J; Eriksson, M; Fujita, T; Kumagi, Y; Stanley, N1
Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K1
Ahn, JH; Kim, JE; Kim, MJ; Kim, SD; Lee, HW; Moon, SO; Park, DJ; Yoon, YR1
Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H1
Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H1
Abe, R; Arinami, H; Hama, N; Maruyama, R; Shimomura, Y1
Akatsu, C; Fukui, H; Hishinuma, S; Kosaka, K; Shoji, M; Uesawa, Y1
Hassan, K1

Reviews

1 review(s) available for chlorpheniramine and fexofenadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for chlorpheniramine and fexofenadine

ArticleYear
Clinical pharmacology of H1-antihistamines in the skin.
    The Journal of allergy and clinical immunology, 2002, Volume: 110, Issue:5

    Topics: Adult; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Male; Skin; Skin Tests; Terfenadine

2002
Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.
    Human psychopharmacology, 2003, Volume: 18, Issue:8

    Topics: Adult; Chlorpheniramine; Choice Behavior; Cognition; Cross-Over Studies; Dibenzoxepins; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Male; Olopatadine Hydrochloride; Psychomotor Performance; Reaction Time; Terfenadine; Time Factors

2003
Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.
    Current medical research and opinion, 2006, Volume: 22, Issue:7

    Topics: Adult; Anti-Allergic Agents; Asian People; Chlorpheniramine; Cognition; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Japan; Male; Middle Aged; Psychomotor Performance; Sleep; Sleep, REM; Terfenadine

2006
The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:10

    Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chlorpheniramine; Cross-Over Studies; Double-Blind Method; Genotype; Half-Life; Histamine H1 Antagonists; Humans; Korea; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Genetic; Sleep; Sleep, REM; Terfenadine

2008

Other Studies

11 other study(ies) available for chlorpheniramine and fexofenadine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography.
    British journal of pharmacology, 1995, Volume: 116, Issue:1

    Topics: Administration, Oral; Adult; Animals; Brain; Carbon Radioisotopes; Chlorpheniramine; Doxepin; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Receptors, Histamine H1; Terfenadine; Tomography, Emission-Computed

1995
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine

2001
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors

2007
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria

2008
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
    International archives of allergy and immunology, 2011, Volume: 155, Issue:1

    Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult

2011
Localized heat urticaria: Positive reaction of preheated autologous serum skin test.
    The Journal of dermatology, 2016, Volume: 43, Issue:9

    Topics: Anaphylaxis; Chlorpheniramine; Desensitization, Immunologic; Drug Therapy, Combination; Histamine H1 Antagonists, Non-Sedating; Hot Temperature; Humans; Influenza, Human; Intradermal Tests; Male; Middle Aged; Serum; Skin; Terfenadine; Urticaria

2016
Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H
    Biochemical pharmacology, 2017, Mar-15, Volume: 128

    Topics: Animals; Aspartic Acid; Cations, Monovalent; Chlorpheniramine; CHO Cells; Cricetulus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Ligands; Mutation; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Histamine H1; Sodium Chloride; Terfenadine

2017
Urticaria and angioedema as a prodromal cutaneous manifestation of SARS-CoV-2 (COVID-19) infection.
    BMJ case reports, 2020, Jul-07, Volume: 13, Issue:7

    Topics: Angioedema; Anti-Allergic Agents; Betacoronavirus; Chlorpheniramine; Coronavirus Infections; COVID-19; Diagnosis, Differential; Female; Humans; Middle Aged; Pandemics; Pneumonia, Viral; Prednisone; Prodromal Symptoms; SARS-CoV-2; Terfenadine; Treatment Outcome; Urticaria

2020