chlorpheniramine and diazepam

chlorpheniramine has been researched along with diazepam in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199012 (33.33)18.7374
1990's3 (8.33)18.2507
2000's14 (38.89)29.6817
2010's7 (19.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Beaumont, K; Di, L; Maurer, TS; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ahmad, S; Houghton, GW; Laidlaw, J; Richens, A1
Bailey, K; By, AW; Lodge, BA1
Chenpanich, K; Chetanasilpin, P; Tuchinda, P1
García Luna, M; Jiménez Vázquez, P1
Maickel, RP; Nash, JF1
Müller-Limmroth, W1
Brittain, RT1
Kendall, BE; Smith, MJ; Tomlinson, S1
James, J; Kirby, JD; Matthews, CN; Warin, RP1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Court, H; Streete, P; Volans, GN1
Evans, S; Henningfield, J; Johanson, CE1
Ketkar, A; Kumar M, K; Mahadik, KR; Paradkar, A; Shah, MH1
Hidir, Y; Satar, B; Yetiser, S1
Faganello, FR; Mattioli, R1
Benlloch Petit, R; Gonzalo González, AA; Jarma Antacle, N; Pérez Martínez, D1

Reviews

2 review(s) available for chlorpheniramine and diazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Recommendations for basic emergency equipment in the dental office].
    Practica odontologica, 1991, Volume: 12, Issue:7

    Topics: Albuterol; Aminophylline; Chlorpheniramine; Dental Offices; Diazepam; Emergencies; Epinephrine; First Aid; Glucose; Humans; Hydrocortisone; Isosorbide

1991

Trials

2 trial(s) available for chlorpheniramine and diazepam

ArticleYear
[The effect of a new analgesic, flupirtine, on psychomotor performance in humans].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:7

    Topics: Aminopyridines; Analgesics; Chlorpheniramine; Diazepam; Humans; Hypnotics and Sedatives; Male; Mental Processes; Psychomotor Performance; Reaction Time

1985
Dermographism: reduction in weal size by chlorpheniramine and hydroxyzine.
    The British journal of dermatology, 1973, Volume: 88, Issue:3

    Topics: Chlorpheniramine; Clinical Trials as Topic; Diazepam; Humans; Hydroxyzine; Skin; Wounds and Injuries

1973

Other Studies

32 other study(ies) available for chlorpheniramine and diazepam

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Volume of Distribution in Drug Design.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Drug Design; Half-Life; Pharmacokinetics

2015
Involuntary movements caused by phenytoin intoxication in epileptic patients.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:3

    Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Movement Disorders; Phenobarbital; Phenytoin; Primidone; Thiazines

1975
Description and chromatographic investigation of Mexican medication for arthritis and asthma, including an unusual corticosteroid.
    Journal of chromatography, 1978, Dec-01, Volume: 166, Issue:1

    Topics: Adrenal Cortex Hormones; Arthritis; Asthma; Capsules; Chlorpheniramine; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Estradiol; Humans; Meprobamate; Methylprednisolone; Mexico; Tablets; Triamcinolone

1978
Effects of some drugs on psychosexual response in man.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1975, Volume: 58, Issue:10

    Topics: Adult; Chlorpheniramine; Diazepam; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Sexual Behavior

1975
Drug interactions with ethanol. Effects on body temperature and motor impairment.
    Neuropharmacology, 1986, Volume: 25, Issue:3

    Topics: Animals; Body Temperature; Chlorpheniramine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Male; Mice; Psychomotor Performance

1986
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
Adverse general reactions to high doses of methylglucamine-based contrast media.
    The British journal of radiology, 1974, Volume: 47, Issue:561

    Topics: Adipates; Adult; Age Factors; Alkaline Phosphatase; Amino Sugars; Calcium; Chlorpheniramine; Contrast Media; Diatrizoate; Diazepam; Drug Hypersensitivity; Fever; Humans; Hyperparathyroidism; Hypotension; Iothalamic Acid; Middle Aged; Muscle Rigidity; Phosphates; Radiography; Sorbitol; Time Factors; Urea; Vomiting

1974
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
Acute poisoning with ibuprofen.
    Human toxicology, 1983, Volume: 2, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpheniramine; Diazepam; Female; Humans; Ibuprofen; Male; Middle Aged

1983
Drugs for the doctor's bag--you respond.
    Drug and therapeutics bulletin, 1995, Volume: 33, Issue:7

    Topics: Chlorpheniramine; Chlorpromazine; Cyclizine; Diazepam; Drug Therapy; Heroin; Humans; Practice Patterns, Physicians'

1995
The discriminative stimulus effects of tripelennamine in humans.
    Psychopharmacology, 1996, Volume: 126, Issue:2

    Topics: Adult; Chlorpheniramine; Dextroamphetamine; Diazepam; Diphenhydramine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Humans; Male; Placebos; Tripelennamine

1996
Effect of drug solubility and different excipients on floating behaviour and release from glyceryl monooleate matrices.
    International journal of pharmaceutics, 2004, Mar-19, Volume: 272, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Chlorpheniramine; Diazepam; Dosage Forms; Drug Carriers; Drug Delivery Systems; Excipients; Glycerides; Polyethylene Glycols; Solubility; Stearic Acids; Time Factors

2004
Effectiveness of hyperbaric oxygen therapy in idiopathic sudden hearing loss.
    The Journal of laryngology and otology, 2006, Volume: 120, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Chi-Square Distribution; Chlorpheniramine; Combined Modality Therapy; Dexamethasone; Diazepam; Drug Therapy, Combination; Female; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Male; Metoclopramide; Middle Aged; Piracetam; Retrospective Studies; Treatment Outcome; Vitamins

2006
Anxiolytic-like effect of chlorpheniramine in inhibitory avoidance in goldfish submitted to telencephalic ablation.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Animals; Anti-Allergic Agents; Anti-Anxiety Agents; Avoidance Learning; Chlorpheniramine; Diazepam; Female; Goldfish; Male; Motor Activity; Telencephalon

2007
[Anesthesia in a woman with cold urticaria].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:9

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anti-Anxiety Agents; Chlorpheniramine; Cold Temperature; Colectomy; Diazepam; Diverticulum; Female; Histamine H1 Antagonists; Histamine Release; Humans; Intraoperative Complications; Laparoscopy; Middle Aged; Postoperative Complications; Preanesthetic Medication; Ranitidine; Sigmoid Diseases; Urticaria

2006