chlorpheniramine and cetirizine

chlorpheniramine has been researched along with cetirizine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's10 (29.41)18.2507
2000's11 (32.35)29.6817
2010's8 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Keserü, GM1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Avdeef, A; Tam, KY1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Boraine, H; Gregorowski, MD; Snyman, JR; Sommers, DK1
Charlesworth, EN; Kagey-Sobotka, A; Lichtenstein, LM; Massey, WA; Norman, PS1
McMillan, JL; Simons, FE; Simons, KJ1
Kaiser, HB1
Snowman, AM; Snyder, SH1
Capron, A; Capron, M; De Vos, C; Joseph, M; Leprevost, C; Tomassini, M; Vorng, H1
Chung, M; Simons, FE; Simons, KJ; Yeh, J1
Doyle, W; Fireman, P; Skoner, D; Tanner, E1
Capron, A; Capron, M; De Vos, C; Leprevost, C; Tomassini, M1
Botha, JJ; Groenewoud, G; Luus, HG; Müller, FO; van Dyk, M1
Arkinstall, WW1
Comer, C; Harvey, RP; Marsh, W; Sanders, B; Shapiro, H; Westley, R; Wiener, M1
Brusasco, V; Crimi, E; Riela, S; Rosadini, G; Sannita, WG1
Fraser, TG; Maher, J; Pillay, N; Simons, FE; Simons, KJ1
Chong, D; Lee, BW; Lee, CY; Ng, KH; Ong, HT; Shek, LP; Wong, CK1
Ramaekers, JG; Theunissen, EL; van Maris, I; van Oers, AC; Vermeeren, A1
Ramaekers, JG; Theunissen, EL; Vermeeren, A1
Chatelain, P; Christophe, B; Gillard, M; Gupta, A; Hammarlund-Udenaes, M; Massingham, R1
Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H1
Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L1
Honda, K; Hori, A; Ikeda, M; Ikeda-Sagara, M; Matsuya, Y; Morioka, E; Ozaki, T; Shahid, M; Toyooka, N; Wada, K1
Chen, B; Chen, J; Du, S; Du, Y; Li, P; Zhang, Q; Zhu, F1
Biagi, C; Calamelli, E; Cipriani, F; Donati, M; Melis, M; Monaco, L; Motola, D; Ricci, G; Vaccheri, A1

Reviews

2 review(s) available for chlorpheniramine and cetirizine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine

1990

Trials

11 trial(s) available for chlorpheniramine and cetirizine

ArticleYear
Effect of cetirizine, ketotifen and chlorpheniramine on the dynamics of the cutaneous hypersensitivity reaction: a comparative study.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Basophils; Cetirizine; Chlorpheniramine; Dermatitis, Contact; Double-Blind Method; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Inflammation; Ketotifen; Mast Cells; Skin Tests; Skin Window Technique; Time Factors

1992
Effect of H1 receptor blockade on the early and late response to cutaneous allergen challenge.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Allergens; Basophils; Cetirizine; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Histamine Release; Humans; Hydroxyzine; Neutrophils; Promethazine; Prostaglandin D2; Skin Tests; Time Factors

1992
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria

1990
Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:3

    Topics: Adult; Cetirizine; Chlorpheniramine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Female; Histamine; Humans; Hydroxyzine; Urticaria

1988
Model for outcomes assessment of antihistamine use for seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1996, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Cetirizine; Chlorpheniramine; Decision Making; Female; Formularies as Topic; Histamine H1 Antagonists; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine

1996
Cutaneous antihistaminic action of cetirizine and dose-related EEG concomitants of sedation in man.
    European journal of pharmacology, 1996, Apr-04, Volume: 300, Issue:1-2

    Topics: Administration, Oral; Adult; Cetirizine; Chlorpheniramine; Consciousness; Cross-Over Studies; Dermatitis, Contact; Dose-Response Relationship, Drug; Electroencephalography; Histamine Antagonists; Humans; Male; Skin Tests

1996
Central nervous system effects of H1-receptor antagonists in the elderly.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:2

    Topics: Aged; Blood Glucose; Brain; Cetirizine; Chlorpheniramine; Cognition Disorders; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Event-Related Potentials, P300; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Loratadine; Male; Memory Disorders; Psychomotor Performance; Safety; Skin Tests; Sleep Stages

1999
Central nervous system side effects of first- and second-generation antihistamines in school children with perennial allergic rhinitis: a randomized, double-blind, placebo-controlled comparative study.
    Pediatrics, 2004, Volume: 113, Issue:2

    Topics: Adolescent; Central Nervous System; Cetirizine; Child; Chlorpheniramine; Cross-Over Studies; Double-Blind Method; Event-Related Potentials, P300; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Prospective Studies; Rhinitis, Allergic, Perennial; Sleep

2004
A dose-ranging study of the effects of mequitazine on actual driving, memory and psychomotor performance as compared to dexchlorpheniramine, cetirizine and placebo.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:2

    Topics: Adult; Automobile Driving; Cetirizine; Chlorpheniramine; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Phenothiazines; Psychometrics; Psychomotor Performance; Statistics, Nonparametric

2004
Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:1

    Topics: Administration, Oral; Adult; Automobile Driving; Cetirizine; Chlorpheniramine; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Phenothiazines; Psychomotor Performance; Self-Assessment

2006
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.
    Respirology (Carlton, Vic.), 2010, Volume: 15, Issue:5

    Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; Cough; Domperidone; Drug Therapy, Combination; Empirical Research; Humans; Methamphetamine; Middle Aged; Noscapine; Omeprazole; Prednisone; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome

2010

Other Studies

21 other study(ies) available for chlorpheniramine and cetirizine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Cetirizine: actions on neurotransmitter receptors.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Animals; Blood-Brain Barrier; Brain; Cetirizine; Chlorpheniramine; Histamine H1 Antagonists; Hydroxyzine; Lung; Rats; Receptors, Histamine H1; Swine

1990
Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine.
    International archives of allergy and applied immunology, 1989, Volume: 88, Issue:1-2

    Topics: Blood Platelets; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Cytotoxicity, Immunologic; Eosinophils; Humans; Hydroxyzine; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor

1989
The comparative pharmacokinetics of H1-receptor antagonists.
    Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2

    Topics: Adult; Age Factors; Astemizole; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cetirizine; Child; Chlorpheniramine; Dose-Response Relationship, Drug; Half-Life; Histamine H1 Antagonists; Humans; Hydroxyzine; Terfenadine

1987
A primate model for the evaluation of antihistamines.
    Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2

    Topics: Administration, Oral; Airway Resistance; Animals; Bronchial Provocation Tests; Cetirizine; Chlorpheniramine; Drug Evaluation; Histamine; Histamine H1 Antagonists; Hydroxyzine; Macaca mulatta; Manometry; Nose; Rhinitis, Allergic, Seasonal; Skin Tests; Software

1987
Inhibition of eosinophil chemotaxis by a new antiallergic compound (cetirizine).
    International archives of allergy and applied immunology, 1988, Volume: 87, Issue:1

    Topics: Cell Survival; Cells, Cultured; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Eosinophils; Exocytosis; Humans; Hydroxyzine; In Vitro Techniques; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor

1988
Fatal anaphylactic reactions to food in children.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1994, Jun-01, Volume: 150, Issue:11

    Topics: Anaphylaxis; Cetirizine; Child; Chlorpheniramine; Epinephrine; Food Hypersensitivity; Humans

1994
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine

2001
Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig.
    British journal of pharmacology, 2007, Volume: 151, Issue:7

    Topics: Administration, Oral; Animals; Anti-Allergic Agents; Blood-Brain Barrier; Brain; Cerebellum; Cetirizine; Chlorpheniramine; Chromatography, Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Half-Life; Histamine H1 Antagonists, Non-Sedating; Ileum; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Pyrilamine; Receptors, Histamine H1; Tandem Mass Spectrometry; Time Factors; Tritium

2007
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria

2008
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride

2009
Induction of prolonged, continuous slow-wave sleep by blocking cerebral H₁ histamine receptors in rats.
    British journal of pharmacology, 2012, Volume: 165, Issue:1

    Topics: Animals; Calcium; Cetirizine; Chlorpheniramine; Fluorescent Dyes; HeLa Cells; Histamine H1 Antagonists; Humans; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Sleep; Staining and Labeling

2012
Study of the enantioseparation capability of chiral dual system based on chondroitin sulfate C in CE.
    Electrophoresis, 2015, Volume: 36, Issue:4

    Topics: Atenolol; beta-Cyclodextrins; Buffers; Cetirizine; Chlorpheniramine; Chondroitin Sulfates; Duloxetine Hydrochloride; Electrophoresis, Capillary; Glycogen; Hydrogen-Ion Concentration; Imidazoles; Isoquinolines; Nefopam; Stereoisomerism; Thiophenes

2015
Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.
    Pharmacoepidemiology and drug safety, 2017, Volume: 26, Issue:10

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Cetirizine; Child; Child Mortality; Child, Preschool; Chlorpheniramine; Databases, Factual; Diphenhydramine; Epilepsy; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Pharmacovigilance; Stevens-Johnson Syndrome; World Health Organization

2017