chlorpheniramine has been researched along with astemizole in 28 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (32.14) | 18.7374 |
1990's | 10 (35.71) | 18.2507 |
2000's | 6 (21.43) | 29.6817 |
2010's | 3 (10.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Abou-Gharbia, M; Moyer, JA; Nielsen, ST; Patel, U; Webb, M | 1 |
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
Keserü, GM | 1 |
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
Caron, G; Ermondi, G | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Jia, L; Sun, H | 1 |
Sen, S; Sinha, N | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, G; Huang, G; Zhou, S | 1 |
Feldman, W; Ham-pong, A; Leiken, L; Peterson, R; Shanon, A | 1 |
Wood, SF | 1 |
McMillan, JL; Simons, FE; Simons, KJ | 1 |
Kaiser, HB | 1 |
Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM | 1 |
Kacker, SK; Sooknundun, M; Sundaram, KR | 1 |
Bhatti, JZ; Hindmarch, I | 1 |
Chung, M; Simons, FE; Simons, KJ; Yeh, J | 1 |
Meltzer, EO | 1 |
Krause, LB; Shuster, S | 1 |
Niemegeers, CJ; Wauquier, A | 1 |
Awouters, F; Janssen, PA; Van den Broeck, WA; Wauquier, A | 1 |
Chen, F; Dai, ZS; Hou, SX | 1 |
Feldman, W; Leikin, L; Peterson, R; Pong, AH; Shanon, A; Williams, V | 1 |
Guinosso, PJ; Jurkiewicz, NK; Lynch, JJ; Salata, JJ; Stupienski, RF; Wallace, AA | 1 |
Crawford, WW; Klaustermeyer, WB; Lee, PH; Placik, IM | 1 |
Chen, Z; Kamei, C; Kawamoto, E; Sugimoto, Y | 1 |
3 review(s) available for chlorpheniramine and astemizole
Article | Year |
---|---|
Central nervous system side-effects of antihistamines in schoolchildren.
Topics: Astemizole; Central Nervous System Diseases; Child; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Sleep Stages | 1992 |
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; Conjunctivitis, Allergic; Humans; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine | 1992 |
H1-receptor antagonist treatment of seasonal allergic rhinitis.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine | 1990 |
6 trial(s) available for chlorpheniramine and astemizole
Article | Year |
---|---|
Central nervous system side-effects of antihistamines in schoolchildren.
Topics: Astemizole; Central Nervous System Diseases; Child; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Sleep Stages | 1992 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
Psychomotor effects of astemizole and chlorpheniramine, alone and in combination with alcohol.
Topics: Adult; Astemizole; Automobile Driving; Benzimidazoles; Chlorpheniramine; Drug Synergism; Ethanol; Female; Histamine H1 Antagonists; Humans; Middle Aged; Psychomotor Performance | 1987 |
A comparison of astemizole and chlorpheniramine in dermographic urticaria.
Topics: Adolescent; Adult; Aged; Astemizole; Benzimidazoles; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Middle Aged; Pruritus; Skin; Sleep Stages; Urticaria | 1985 |
Comparison of CNS adverse effects between astemizole and chlorpheniramine in children: a randomized, double-blind study.
Topics: Adolescent; Astemizole; Attention; Behavior; Central Nervous System; Child; Chlorpheniramine; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Memory, Short-Term; Multivariate Analysis; Patient Compliance; Psychomotor Performance; Rhinitis, Allergic, Seasonal | 1993 |
Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis.
Topics: Adrenergic Agents; Allergens; Ambulatory Care; Analysis of Variance; Anti-Allergic Agents; Astemizole; Bronchodilator Agents; Chlorpheniramine; Confidence Intervals; Cross-Over Studies; Ephedrine; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Nasal Mucosa; Nose; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome | 1998 |
20 other study(ies) available for chlorpheniramine and astemizole
Article | Year |
---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
New antihistamines: substituted piperazine and piperidine derivatives as novel H1-antagonists.
Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Male; Motor Activity; Piperazines; Piperidines; Rats; Structure-Activity Relationship | 1995 |
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, synthesis and biological activity of a novel ethylenediamine derivatives as H
Topics: Animals; Basophils; Cell Line; Chlorpheniramine; Drug Design; Ethylenediamines; Female; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Mice; Models, Molecular; Molecular Structure; Protein Conformation; Random Allocation; Rats; Receptors, Histamine H1 | 2019 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine | 1989 |
Treatment of allergic rhinitis with a new long-acting H1 receptor antagonist: astemizole.
Topics: Adult; Appetite; Astemizole; Benzimidazoles; Chlorpheniramine; Drug Evaluation; Female; Histamine H1 Antagonists; Humans; Male; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Xerostomia | 1987 |
The comparative pharmacokinetics of H1-receptor antagonists.
Topics: Adult; Age Factors; Astemizole; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cetirizine; Child; Chlorpheniramine; Dose-Response Relationship, Drug; Half-Life; Histamine H1 Antagonists; Humans; Hydroxyzine; Terfenadine | 1987 |
The use of antihistamines for the treatment of airway disease.
Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Child; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine | 1988 |
Effects of chlorpheniramine, pyrilamine and astemizole on intracranial self-stimulation in rats.
Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Histamine H1 Antagonists; Neurotransmitter Agents; Physostigmine; Pupil; Pyrilamine; Rats; Self Stimulation | 1981 |
A comparison between astemizole and other antihistamines on sleep-wakefulness cycles in dogs.
Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Diphenhydramine; Dogs; Histamine H1 Antagonists; Ketotifen; Male; Periodicity; Pyrilamine; Sleep; Sleep Stages; Sleep, REM; Wakefulness | 1981 |
Inhibitory effects of chlorpheniramine and astemizolum on contraction of isolated rat and rabbit uteri induced by oxytocin and PGF2 alpha.
Topics: Animals; Astemizole; Chlorpheniramine; Dinoprostone; Female; In Vitro Techniques; Oxytocin; Rabbits; Rats; Rats, Wistar; Uterine Contraction | 1994 |
Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine.
Topics: Action Potentials; Animals; Astemizole; Chlorpheniramine; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Potassium Channels; Pyrilamine; Refractory Period, Electrophysiological; Terfenadine | 1995 |
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
Topics: Allergens; Animals; Anti-Allergic Agents; Astemizole; Chlorpheniramine; Dibenzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Imidazoles; Immunization; Ketotifen; Nasal Cavity; Ovalbumin; Passive Cutaneous Anaphylaxis; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial; Sneezing; Time Factors | 2000 |