chlorothiazide and probenecid

chlorothiazide has been researched along with probenecid in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (87.50)	18.7374
1990's	1 (2.50)	18.2507
2000's	3 (7.50)	29.6817
2010's	1 (2.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Beyer, KH	1
Brater, DC	1
Dehner, EJ; Martin, ET; Schwartz, JB	1
Baer, JE; Beyer, KH	1
Bonet Domingo, E; García Alvarez-Coque, MC; Medina Hernández, MJ; Ramis Ramos, G	1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K	1
Gigon, PL; Guarino, AM	1
Krebs, A; Zürcher, K	1
Boner, G; Steele, TH	1
Fanelli, GM; Weiner, IM	1
Healey, LA; Skeith, MD	1
Dawson, D	1
McMahon, FG	1
Bohn, DL; Fanelli, GM; Reilly, SS	2
Ina, K; Ito, M; Suzuki, Y; Yamagami, I	1
Foulkes, EC; Nolan, RP	1
Klaassen, CD	1
Berndt, WO; McAlary, B; Mudge, GH	1
Barac-Nieto, M; Cohen, JJ	1
Adamson, RH; Guarino, AM; Hart, LG	1
Thompson, GR	1
Guidotti, FP; Lapidus, PW	1
Binder, HJ; Katz, LA; Spencer, RP; Spiro, HM	1
Hart, LG; Schanker, LS	1
Brest, AN; Heider, C; Mehbod, H; Onesti, G	1
Duggan, DE	1
Benet, LZ; Gustafson, JH	1
BRANCACCIO, A; D'ALESSANDRO, B; DE LUCA, R; JACONO, G	1
ADAMS, JF	1
MASON, RM	1
CASTLES, TR; WILLIAMSON, HE	1
BEECHWOOD, EC; BERNDT, WO; MUDGE, GH	1
SILBERSTEIN, EB	1
KUNIN, CM	1
CHINARD, FP; ENNS, T; GORESKY, CA; NOLAN, MF	1

Reviews

1 review(s) available for chlorothiazide and probenecid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for chlorothiazide and probenecid

Article	Year
Uricosurics and xanthine oxidase inhibitors: a single-dose assay. Current therapeutic research, clinical and experimental, 1970, Volume: 12, Issue:6 Topics: Adult; Allopurinol; Chlorothiazide; Humans; Male; Methods; Placebos; Probenecid; Uric Acid; Uricosuric Agents; Xanthine Oxidase	1970

Other Studies

38 other study(ies) available for chlorothiazide and probenecid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
A career or two. Annual review of pharmacology and toxicology, 1977, Volume: 17 Topics: Animals; Chemistry, Pharmaceutical; Chlorothiazide; History, 20th Century; Humans; Penicillins; Pharmacology; Probenecid; United States	1977
Increase in diuretic effect of chlorothiazide by probenecid. Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:3 Topics: Adult; Chlorothiazide; Diuresis; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Natriuresis; Probenecid	1978
Intragranular starch: comparison of starch USP and modified cornstarch. Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:2 Topics: Acetaminophen; Ascorbic Acid; Biopharmaceutics; Cellulose; Chlorothiazide; Dihydroxyphenylalanine; Excipients; Hardness Tests; Kinetics; Methyldopa; Pressure; Probenecid; Solubility; Starch; Tablets	1975
The site and mode of action of some sulfonamide-derived diuretics. The Medical clinics of North America, 1975, Volume: 59, Issue:3 Topics: Acetazolamide; Aminohippuric Acids; Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Chlorides; Chlorothiazide; Chlorthalidone; Cyclopenthiazide; Depression, Chemical; Dichlorphenamide; Diffusion; Diuretics; Hydrochlorothiazide; Kidney Cortex; Kidney Medulla; Natriuresis; Probenecid; Rabbits; Sodium; Trichlormethiazide	1975
High-performance liquid chromatographic determination of diuretics in urine by micellar liquid chromatography. Journal of chromatography, 1992, Nov-06, Volume: 582, Issue:1-2 Topics: Acetazolamide; Bendroflumethiazide; Chlorothiazide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Micelles; Probenecid; Sodium Dodecyl Sulfate	1992
Distribution of chlorpromazine in a simplified blood influenced by various drugs. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1 Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental	1973
Uptake of probenecid by rat liver slices. Biochemical pharmacology, 1970, Volume: 19, Issue:9 Topics: Animals; Biological Transport, Active; Carbon Isotopes; Chlorothiazide; Chromatography, Gas; Cyanides; Filtration; Glucuronates; Imides; In Vitro Techniques; Iodoacetates; Iopanoic Acid; Liver; Male; Maleates; NAD; Phlorhizin; Probenecid; Procainamide; Protein Binding; Rats; Sodium; Sulfobromophthalein; Triazines; Ultracentrifugation	1970
[Cutaneous side effects of systemic drugs with special reference to recently introduced medicaments. I]. Dermatologica, 1970, Volume: 141, Issue:2 Topics: Allopurinol; Analgesics; Chlorothiazide; Colchicine; Drug Eruptions; Humans; Lichen Planus; Photosensitivity Disorders; Probenecid; Quinolines; Stevens-Johnson Syndrome; Sulfinpyrazone	1970
Origins of the uricosuric response. The Journal of clinical investigation, 1973, Volume: 52, Issue:6 Topics: Adult; Aminohippuric Acids; Chlorothiazide; Female; Glomerular Filtration Rate; Humans; Inulin; Kidney; Male; Middle Aged; Natriuresis; Phosphates; Phosphorus; Probenecid; Pyrazinamide; Sodium; Uric Acid; Urination	1973
Pyrazinoate excretion in the chimpanzee. Relation to urate disposition and the actions of uricosuric drugs. The Journal of clinical investigation, 1973, Volume: 52, Issue:8 Topics: Allopurinol; Aminohippuric Acids; Animals; Biological Transport; Carboxylic Acids; Chlorothiazide; Depression, Chemical; Glomerular Filtration Rate; Insulin; Iodopyracet; Kidney Tubules; Male; Organomercury Compounds; Pan troglodytes; Probenecid; Protein Binding; Pyrazines; Salicylates; Stimulation, Chemical; Sulfinpyrazone; Uric Acid; Uricosuric Agents	1973
Urate clearance in Cebus monkeys. The American journal of physiology, 1968, Volume: 214, Issue:3 Topics: Animals; Chlorothiazide; Cobalt Isotopes; Creatinine; Glomerular Filtration Rate; Haplorhini; Hydroxybutyrates; Inulin; Kidney; Lactates; Probenecid; Sulfinpyrazone; Uric Acid; Vitamin B 12	1968
Chlorothiazide and probenecid in the treatment of hypertension and hyperuricemia. Current therapeutic research, clinical and experimental, 1968, Volume: 10, Issue:5 Topics: Chlorothiazide; Female; Glucose Tolerance Test; Humans; Hypertension; Male; Middle Aged; Probenecid; Uric Acid	1968
Renal effects of uricosuric agents in the Cebus monkey. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: Administration, Oral; Amides; Aminohippuric Acids; Animals; Biotransformation; Chlorothiazide; Glomerular Filtration Rate; Haplorhini; Injections, Intravenous; Inulin; Iodopyracet; Kidney; Phenylbutazone; Probenecid; Species Specificity; Sulfinpyrazone; Uric Acid; Uricosuric Agents; Zoxazolamine	1970
[Pharmacological studies of diuretics. 4. Changes of serum uric acid level by the succesive administration of thiazide diuretics and other drugs and effects of uricosuric drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:1 Topics: Administration, Oral; Allopurinol; Ammonium Chloride; Animals; Barbiturates; Blood Glucose; Chlorothiazide; Cyclohexanes; Diuretics; Electrolytes; Ethacrynic Acid; Glycine; Hydrochlorothiazide; Hydroflumethiazide; Injections, Subcutaneous; Male; Nucleosides; Phenylbutazone; Probenecid; Quinolines; Rats; Sulfinpyrazone; Sulfonamides; Thiadiazines; Uric Acid; Uricosuric Agents; Xanthenes	1971
Studies on renal urate secretion in the dog. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:2 Topics: Aminohippuric Acids; Animals; Carbon Isotopes; Chlormerodrin; Chlorothiazide; Dogs; Ethacrynic Acid; Female; Furosemide; Inulin; Kidney; Lactates; Male; Probenecid; Pyrazines; Renal Artery; Time Factors; Tritium; Uric Acid	1971
Effects of phenobarbital on the plasma disappearance and biliary excretion of drugs in rats. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Chlorothiazide; Coloring Agents; Indocyanine Green; Male; Ouabain; Phenobarbital; Phenols; Probenecid; Procainamide; Rats; Succinates; Sulfathiazoles; Sulfobromophthalein	1970
Renal effects of uricosuric agents in the chimpanzee. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3 Topics: Aminohippuric Acids; Animals; Benzoates; Benzyl Compounds; Chlorothiazide; Electrolytes; Glomerular Filtration Rate; Hominidae; Hydrochlorothiazide; Inulin; Iodopyracet; Kidney; Male; Probenecid; Sodium Salicylate; Sulfinpyrazone; Sulfonamides; Uric Acid; Uricosuric Agents; Zoxazolamine	1971
Renal transport of uric acid in the guinea pig. The American journal of physiology, 1968, Volume: 214, Issue:4 Topics: Absorption; Animals; Biological Transport; Chlorothiazide; Depression, Chemical; Female; Guinea Pigs; Inulin; Kidney Tubules; Lactates; Male; Ouabain; Probenecid; Pyrazines; Uric Acid	1968
Nonesterified fatty acid uptake by dog kidney: effects of probenecid and chlorothiazide. The American journal of physiology, 1968, Volume: 215, Issue:1 Topics: Aminohippuric Acids; Animals; Biological Transport, Active; Cell Membrane Permeability; Chlorothiazide; Creatinine; Dogs; Fatty Acids, Nonesterified; Female; Glomerular Filtration Rate; Hematocrit; Hydrogen-Ion Concentration; Iodine Isotopes; Iodopyracet; Kidney; Kidney Tubules; Mannitol; Probenecid; Regional Blood Flow; Sodium	1968
Effects of phenobarbital on biliary excretion of organic acids in male and female rats. The American journal of physiology, 1969, Volume: 217, Issue:1 Topics: Animals; Bile; Biliary Tract; Chlorothiazide; Female; Glucuronates; Indocyanine Green; Male; Phenobarbital; Phenolphthaleins; Probenecid; Rats; Sex Factors	1969
The effect of diazoxide, potassium chloride, and ammonium chloride on serum and urinary uric acid. Arthritis and rheumatism, 1965, Volume: 8, Issue:5 Topics: Ammonium Chloride; Antihypertensive Agents; Blood; Chlorothiazide; Diazoxide; Humans; Potassium Chloride; Probenecid; Uric Acid; Urine	1965
Gout in orthopaedic practice: review of 232 cases. Clinical orthopaedics and related research, 1963, Volume: 28 Topics: Acute Disease; Adolescent; Aged; Bone Diseases; Chlorothiazide; Colchicine; Diagnosis, Differential; Diet; Female; Gout; Humans; Male; Middle Aged; Osteoarthritis; Prednisolone; Probenecid; Radiography; Uric Acid	1963
The effect of inhibitors of renal transport on the small intestine. The Journal of clinical investigation, 1966, Volume: 45, Issue:12 Topics: Animals; Biological Transport; Chlorothiazide; Cricetinae; Ethacrynic Acid; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Lysine; Methionine; Probenecid; Uracil	1966
Active transport of chlorothiazide into bile. The American journal of physiology, 1966, Volume: 211, Issue:3 Topics: Aminohippuric Acids; Animals; Bile; Biological Transport, Active; Chlorothiazide; Probenecid; Protein Binding; Rats	1966
Drug control of diuretic-induced hyperuricemia. JAMA, 1966, Jan-03, Volume: 195, Issue:1 Topics: Blood; Chlorothiazide; Humans; Hydrochlorothiazide; Hypertension; Probenecid; Sulfonamides; Uric Acid	1966
A biochemical basis for the renal activity of N-7-acetylchlorothiazide. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:1 Topics: Acetates; Animals; Carbon Isotopes; Chlorothiazide; Chromatography; In Vitro Techniques; Kidney; Male; Ouabain; Probenecid; Rabbits	1967
Saturable kinetics of intravenous chlorothiazide in the rhesus monkey. Journal of pharmacokinetics and biopharmaceutics, 1981, Volume: 9, Issue:4 Topics: Animals; Biological Availability; Blood Proteins; Chlorothiazide; Dose-Response Relationship, Drug; Injections, Intravenous; Kidney Glomerulus; Kinetics; Macaca mulatta; Probenecid; Protein Binding	1981
The effect of probenecid and hydrochlorothiazide on the clearances of free and conjugated 17-hydroxycorticosteroids, total 17-ketosteroids, dehydroepiandrosterone and androsterone. Endocrinology, 1961, Volume: 69 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Chlorothiazide; Dehydroepiandrosterone; Humans; Hydrochlorothiazide; Probenecid	1961
The effect of some drugs and of differing routes of administration on the urinary excretion of parenteral vitamin B12. Clinical science, 1963, Volume: 24 Topics: Arginine Vasopressin; Chlorothiazide; Diuretics; Organomercury Compounds; Pharmaceutical Preparations; Probenecid; Vasopressins; Vitamin B 12	1963
INFLAMMATORY POLYARTHRITIC DISEASE. IV. GOUT. The Journal of the College of General Practitioners, 1963, Volume: 6 Topics: Arthritis; Aspirin; Chlorothiazide; Colchicine; Gout; Hydrochlorothiazide; Mecamylamine; Pempidine; Phenylbutazone; Probenecid; Pyrazoles; Salicylates	1963
THE EFFECT OF CHLOROTHIAZIDE ON THE EXCRETION OF URIC ACID AND ELECTROLYTES BY THE CHICKEN. The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142 Topics: Animals; Biological Transport; Chickens; Chlorides; Chlorothiazide; Kidney Function Tests; Niacin; Niacinamide; Pharmacology; Potassium; Poultry; Probenecid; Research; Sodium; Uric Acid; Urine	1963
STOP-FLOW ANALYSIS OF TUBULAR TRANSPORT OF URIC ACID IN RABBITS. The American journal of physiology, 1964, Volume: 207 Topics: Animals; Biological Transport; Body Fluids; Chlorothiazide; Creatine; Creatinine; Glomerular Filtration Rate; Inulin; Kidney Tubules; Lactates; Metabolism; Pharmacology; Physiology; Probenecid; Pyrazines; Rabbits; Research; Salicylates; Uric Acid; Urine	1964
ERYSIPELOTHRIX ENDOCARDITIS: REPORT OF A CASE WITH CEREBRAL MANIFESTATIONS. JAMA, 1965, Mar-08, Volume: 191 Topics: Brain Diseases; Chloramphenicol; Chlorothiazide; Digoxin; Diuretics; Drug Therapy; Endocarditis; Endocarditis, Bacterial; Erysipelothrix; Heart Failure; Heart Valve Diseases; Humans; Methicillin; Organomercury Compounds; Penicillin V; Penicillins; Probenecid; Sepsis	1965
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS. The Journal of laboratory and clinical medicine, 1965, Volume: 65 Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide	1965
RENAL TRANSIT TIMES AND DISTRIBUTION VOLUMES OF T-1824, CREATININE, AND WATER. The American journal of physiology, 1965, Volume: 209 Topics: Animals; Blood Volume; Body Fluids; Capillary Permeability; Chlorothiazide; Coloring Agents; Creatine; Creatinine; Diatrizoate; Dogs; Dye Dilution Technique; Extracellular Space; Fructose; Hippurates; Inulin; Iodopyracet; Kidney; Probenecid; Research; Water; Water-Electrolyte Balance	1965