chlorothiazide and prazosin

chlorothiazide has been researched along with prazosin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fang, P; Hua, AS; Kincaid-Smith, P; Macdonald, IM; Myers, JB1
Grenfell, RF1
Conway, EL; Drummer, OH; Howes, LG; Louis, WJ; McNeil, JJ; Meng, L; Raymond, K1
Donker, AJ; May, JF; Schuurman, FH; ten Berge, BS; van der Veur, E; Wesseling, H1

Reviews

1 review(s) available for chlorothiazide and prazosin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for chlorothiazide and prazosin

ArticleYear
Studies with prazosin--a new effective hypotensive agent. II. Two double-blind cross-over studies comparing the effects of prazosin and hydrallazine.
    The Medical journal of Australia, 1977, Jul-02, Volume: 2, Issue:1

    Topics: Adult; Chlorothiazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Quinazolines

1977
A comparison of labetalol and prazosin combined with atenolol in non-responders to atenolol plus hydrochlorothiazide in uncomplicated hypertension.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adult; Atenolol; Chlorothiazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Prazosin; Random Allocation; Time Factors

1985

Other Studies

5 other study(ies) available for chlorothiazide and prazosin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Treatment of chronic essential hypertension.
    Comprehensive therapy, 1977, Volume: 3, Issue:5

    Topics: Chlorothiazide; Clonidine; Diabetes Mellitus; Diet, Sodium-Restricted; Gout; Guanethidine; Humans; Hydralazine; Hypertension; Hypnotics and Sedatives; Medical History Taking; Methyldopa; Patient Compliance; Physical Examination; Phytotherapy; Plants, Medicinal; Potassium; Prazosin; Prognosis; Propranolol; Rauwolfia; Sympathectomy; Tranquilizing Agents

1977
Single-dose and steady-state pharmacokinetics of doxazosin given in combination with chlorothiazide to hypertensive subjects.
    Clinical pharmacokinetics, 1989, Volume: 16, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Doxazosin; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Prazosin

1989