chlorothiazide and amiloride

chlorothiazide has been researched along with amiloride in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's5 (18.52)18.2507
2000's4 (14.81)29.6817
2010's6 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carney, S; Matthews, G; Morgan, T; Roberts, R; Wilson, M1
Costanzo, LS; Weiner, IM1
Maxwell, MR; McAteer, JA; Tanner, GA1
Smeda, JS; Tkachenko, O1
Gray, JA; Kavlock, RJ2
Velázquez, H; Wright, FS1
Grantham, J; Middendorf, D1
Christensen, OE; Fariello, R; Muiesan, G; Muiesan, ML1
Blair-West, JR; Nelson, JF; Wright, RD1
Costanzo, LS1
Baer, JE; Beyer, KH1
Leemhuis, MP; Struyvenberg, A1
Meinders, AE1
Friedman, PA; Gesek, FA1
Beal, AM1
Amiel, C; Couloigner, V; Ferrary, E; Loiseau, A; Sterkers, O1
Burgess, DW; Miarczynski, MD; O'Donnell, MJ; Wood, CM1
Chapman, MD; Hanrahan, R; Marley, JE; McEwen, J1
Gildea, JJ; Howell, NL; Keller, SR; Kemp, BA; Padia, SH1
Abdelaleem, EA; Draz, ME; Naguib, IA; Zaazaa, HE1
Aliaga, S; Chantala, K; Clark, RH; Herring, AH; Hornik, CP; Hughes, R; Laughon, MM; Smith, PB1

Reviews

3 review(s) available for chlorothiazide and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Subcellular pharmacology of natriuretic and potassium-sparing drugs.
    Progress in biochemical pharmacology, 1972, Volume: 7

    Topics: Adenosine Triphosphatases; Aldosterone; Amiloride; Animals; Biological Transport, Active; Cardiac Glycosides; Chlorothiazide; Diuretics; Ethacrynic Acid; Glycolysis; Humans; Kidney; Membranes; Natriuresis; Nephrons; Potassium; Sodium; Structure-Activity Relationship; Subcellular Fractions

1972
Significance of hypokalaemia due to diuretics.
    The Netherlands journal of medicine, 1973, Volume: 16, Issue:1

    Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Furosemide; Hepatic Encephalopathy; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Tubules; Liver Cirrhosis; Natriuresis; Potassium; Potassium Chloride; Spironolactone; Triamterene

1973

Trials

1 trial(s) available for chlorothiazide and amiloride

ArticleYear
Effect of pinacidil on blood pressure, plasma catecholamines and plasma renin activity in essential hypertension.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Body Weight; Catecholamines; Chlorothiazide; Clinical Trials as Topic; Epinephrine; Female; Guanidines; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pinacidil; Random Allocation; Renin

1985

Other Studies

23 other study(ies) available for chlorothiazide and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Sodium restriction and thiazide diuretics in the treatment of hypertension.
    The Medical journal of Australia, 1975, Jun-28, Volume: 1, Issue:26

    Topics: Amiloride; Bicarbonates; Body Weight; Chlorothiazide; Diet, Sodium-Restricted; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Potassium Chloride; Sodium Chloride Symporter Inhibitors; Uric Acid

1975
Relationship between clearances of Ca and Na: effect of distal diuretics and PTH.
    The American journal of physiology, 1976, Volume: 230, Issue:1

    Topics: Amiloride; Animals; Calcium; Chlorothiazide; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Glomerular Filtration Rate; Parathyroid Glands; Parathyroid Hormone; Sodium; Thyroid Gland; Triamterene

1976
Fluid transport in a cultured cell model of kidney epithelial cyst enlargement.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport; Bucladesine; Bumetanide; Cell Division; Cells, Cultured; Chlorides; Chlorothiazide; Culture Techniques; Dogs; Intracellular Fluid; Kidney; Kidney Diseases, Cystic; Mice; Ouabain; Solutions

1992
Effects of diuretics on stroke development in Kyoto-Wistar stroke-prone spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1991, Volume: 81, Issue:3

    Topics: Acetazolamide; Amiloride; Animals; Cerebrovascular Disorders; Chlorothiazide; Diet; Diuretics; Furosemide; Hypertension; Male; Potassium; Rats; Rats, Inbred SHR

1991
Pharmacologic probing of mercuric chloride-induced renal dysfunction in the neonatal rat.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Acetazolamide; Amiloride; Animals; Animals, Newborn; Chlorothiazide; Diuretics; Furosemide; Kidney; Kidney Diseases; Mercuric Chloride; Rats; Rats, Inbred Strains

1987
Effects of diuretic drugs on Na, Cl, and K transport by rat renal distal tubule.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 2

    Topics: Amiloride; Animals; Biological Transport; Bumetanide; Chlorides; Chlorothiazide; Diuretics; Furosemide; Kidney Tubules; Kidney Tubules, Distal; Male; Potassium; Rats; Rats, Inbred Strains; Sodium

1986
Pharmacologic probing of renal development in the neonatal rat.
    Biology of the neonate, 1986, Volume: 50, Issue:4

    Topics: Acetazolamide; Amiloride; Animals; Animals, Newborn; Chlorides; Chlorothiazide; Diuresis; Diuretics; Furosemide; Hydrogen-Ion Concentration; Kidney; Organomercury Compounds; Osmolar Concentration; Rats; Rats, Inbred Strains; Urine

1986
Profound pharmacologic inhibition of renal tubule sodium and water reabsorption in rats.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:4

    Topics: Acetazolamide; Amiloride; Animals; Body Water; Chlorothiazide; Diuretics; Female; Furosemide; Kidney Tubules; Kinetics; Rats; Sodium; Vanadates; Vanadium

1985
Effects of ouabain, amiloride, monensin, and other agents on ovine parotid secretion.
    The American journal of physiology, 1986, Volume: 250, Issue:3 Pt 2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Chlorothiazide; Ethacrynic Acid; Furans; Furosemide; Kidney; Monensin; Ouabain; Oxygen Consumption; Parotid Gland; Regional Blood Flow; Sheep

1986
Localization of diuretic action in microperfused rat distal tubules: Ca and Na transport.
    The American journal of physiology, 1985, Volume: 248, Issue:4 Pt 2

    Topics: Absorption; Amiloride; Animals; Biological Transport; Calcium; Chlorothiazide; Diuresis; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney Tubules; Kidney Tubules, Distal; Male; Natriuresis; Perfusion; Potassium; Rats; Rats, Inbred Strains; Sodium

1985
[Severe hyponatremia with only minimal hypovolemia].
    Nederlands tijdschrift voor geneeskunde, 1982, Apr-03, Volume: 126, Issue:14

    Topics: Aged; Amiloride; Blood Volume; Chlorothiazide; Diuretics; Humans; Inappropriate ADH Syndrome; Kidney Tubules; Male

1982
Sodium entry mechanisms in distal convoluted tubule cells.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenoviridae; Amiloride; Animals; Bicarbonates; Biological Transport, Active; Bumetanide; Carbonic Anhydrase Inhibitors; Cell Line, Transformed; Chimera; Chlorides; Chlorothiazide; Kidney Tubules, Distal; Kinetics; Mice; Nystatin; Ouabain; Oxygen Consumption; Simian virus 40; Sodium; Sodium Channel Blockers; Sodium Chloride; Sodium Radioisotopes

1995
Mechanisms of fluid and ion secretion by the parotid gland of the kangaroo, Macropus rufus, assessed by administration of transport-inhibiting drugs.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1995, Volume: 165, Issue:5

    Topics: Amiloride; Animals; Bicarbonates; Blood Pressure; Bumetanide; Carotid Arteries; Chlorothiazide; Diuretics; Electrolytes; Ethacrynic Acid; Female; Furosemide; Heart Rate; Ion Transport; Macropodidae; Male; Methazolamide; Osmolar Concentration; Parotid Gland; Regional Blood Flow; Saliva

1995
Effect of locally applied drugs on the endolymphatic sac potential.
    The Laryngoscope, 1998, Volume: 108, Issue:4 Pt 1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Acid-Base Imbalance; Amiloride; Animals; Anti-Bacterial Agents; Bumetanide; Carbonates; Carbonic Anhydrase Inhibitors; Chloride Channels; Chlorothiazide; Diuretics; Endolymph; Endolymphatic Hydrops; Endolymphatic Sac; Enzyme Inhibitors; Epithelium; Guinea Pigs; Ion Transport; Macrolides; Male; Membrane Potentials; Meniere Disease; Ouabain; Potassium Channel Blockers; Proton-Translocating ATPases; Sodium Channel Blockers; Sodium Chloride; Sodium Chloride Symporter Inhibitors; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Time Factors

1998
Na(+) and Cl(-) transport by the urinary bladder of the freshwater rainbow trout (Oncorhynchus mykiss).
    The Journal of experimental zoology, 2000, Jun-15, Volume: 287, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Bumetanide; Chlorides; Chlorothiazide; Electrophysiology; In Vitro Techniques; Ion Transport; Oncorhynchus mykiss; Sodium; Sodium Cyanide; Urinary Bladder

2000
Hyponatraemia and hypokalaemia due to indapamide.
    The Medical journal of Australia, 2002, Mar-04, Volume: 176, Issue:5

    Topics: Amiloride; Australia; Chlorothiazide; Diuretics; Drug Combinations; Drug Utilization; Humans; Hydrochlorothiazide; Hypokalemia; Hyponatremia; Indapamide; Sodium Chloride Symporter Inhibitors

2002
Intrarenal ghrelin receptors regulate ENaC-dependent sodium reabsorption by a cAMP-dependent pathway.
    Kidney international, 2013, Volume: 84, Issue:3

    Topics: Amiloride; Animals; Blood Pressure; Chlorothiazide; Cyclic AMP; Epithelial Sodium Channels; Female; Ghrelin; Immediate-Early Proteins; Kidney Tubules, Collecting; Models, Animal; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Signal Transduction; Sodium

2013
Simultaneous determination of hydrochlorothiazide and benazepril hydrochloride or amiloride hydrochloride in presence of hydrochlorothiazide impurities: chlorothiazide and salamide by HPTLC method.
    Journal of chromatographic science, 2015, Volume: 53, Issue:1

    Topics: Amiloride; Benzazepines; Chlorothiazide; Chromatography, High Pressure Liquid; Drug Contamination; Hydrochlorothiazide

2015
Diuretic exposure in premature infants from 1997 to 2011.
    American journal of perinatology, 2015, Volume: 32, Issue:1

    Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Female; Furosemide; Humans; Hydrochlorothiazide; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Mannitol; Metolazone; Off-Label Use; Respiration, Artificial; Retrospective Studies; Spironolactone; Thrombocytopenia

2015