chloroquine and zithromax

chloroquine has been researched along with zithromax in 133 studies

Research

Studies (133)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (3.01)	18.2507
2000's	17 (12.78)	29.6817
2010's	35 (26.32)	24.3611
2020's	77 (57.89)	2.80

Authors

Authors	Studies
Dunne, MW; Fidock, DA; Nkrumah, LJ; Sacchettini, JC; Sidhu, AB; Sun, Q	1
Fukuda, M; Jongsakul, K; Knirsch, C; Krudsood, S; Leowattana, W; Looareesuwan, S; Miller, RS; Noedl, H; Ohrt, C; Sriwichai, S; Tangpukdee, N; Thanachartwet, W; Yingyuen, K	1
Dennull, RA; Gerena, L; Johnson, JD; Lopez-Sanchez, M; Roncal, NE; Waters, NC	1
Dahl, EL; Rosenthal, PJ	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Fuehrer, HP; Haque, R; Hofecker, V; Khan, WA; Ley, B; Noedl, H; Siedl, A; Starzengruber, P; Thriemer, K; Wernsdorfer, WH	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ellis, W; Hutinec, A; Milhous, W; Ohrt, C; Rupčić, R; Schönfeld, ZI; Smith, KS; Ziher, D	1
Ager, A; Alihodžić, S; Bukvić Krajačić, M; Ellis, WY; Fajdetić, A; Hutinec, A; Ivezić-Schönfeld, Z; Jelić, D; Landek, G; Mesić, M; Milhous, WK; Ohrt, C; Padovan, J; Perić, M; Rupčić, R; Smith, KS; Spaventi, R; Ziher, D	1
Alihodžić, S; Ferrer, S; Herreros, E; Landek, G; Perić, M; Pešić, D; Spaventi, R; Starčević, K; Toplak, A	1
Alihodžić, S; Almela, MJ; Herreros, E; Jelić, D; Perić, M; Pešić, D; Spaventi, R; Starčević, K; Toplak, A; Vidal, J	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Bello, AM; Crandall, IE; Kain, KC; Kotra, LP; Malhotra, P; Mohmmed, A; Pai, EF; Wasilewski, E	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y	1
Beus, M; Fallarero, A; Patel, JZ; Savijoki, K; Yli-Kauhaluoma, J; Zorc, B	1
Gingras, BA; Jensen, JB	2
Andersen, SL; Ballou, WR; Foulds, G; Hall, T; Heppner, DG; Kuschner, RA; Sadoff, JC; Schneider, I; Schuster, B; Wellde, BT	1
Davis, TM	1
Puri, SK; Singh, N	1
Kain, KC; Keystone, JS; Shanks, GD	1
Brasseur, R; Chanteux, H; Mingeot-Leclercq, MP; Paternotte, I; Sonveaux, E; Tulkens, PM	1
Benner, R; Bhattacharyya, PC; Dev, V; Dunne, MW; Lakhani, J; Lele, C; Mohapatra, MK; Patel, K; Patki, K; Shukla, M; Singh, N; Valecha, N	1
Adak, T; Bhattacharyya, PC; Dev, V; Devi, CU; Dunne, MW; Lakhani, J; Lele, C; Mohapatra, MK; Patel, K; Patki, K; Shukla, M; Singh, N; Valecha, N; Yadav, RS	1
Bramson, CR; Cook, JA; Randinitis, EJ; Wesche, DL	1
Deng, S; Duncan, JN; Dunne, M; Fossa, AA; Wisialowski, T	1
Basque, J; Cantin, AM; Leduc, R; Martel, M	1
Chandramohan, D; Chico, RM; Greenwood, B; Pittrof, R	1
Baiwog, F; Davis, TM; Gomorai, S; Griffin, S; Ilett, KF; Kandai, J; Karunajeewa, HA; Kose, K; Mueller, I; O'Halloran, SJ; Rogerson, SJ; Salman, S; Siba, P; Winmai, J	1
Chandramohan, D; Chico, RM	2
Terlouw, DJ; van Eijk, AM	1
Chandra, R; Djimde, A; Fidock, DA; Gore, K; Hardink, J; Henrich, PP; Johnson, D; Lin, J; O'Brien, C; Pereira, MR; Sidhu, AB; Van Deusen, J; Wele, M	1
Friesen, J; Matuschewski, K	1
Dzinjalamala, FK; Laufer, MK; Laurens, MB; Masonga, R; Nyirenda, OM; Plowe, CV; Stokes-Riner, A; Taylor, TE; Thesing, PC	1
Du Plessis, LH; Kotzé, AF; Maritz, MM; van Niekerk, AC	1
Banjanac, M; Eraković Haber, V; Munić, V; Nujić, K; Polančec, D	1
Goodman, CD; Gramajo, H; Labadie, GR; McFadden, GI; Peirú, S; Rodríguez, E; Useglio, M	1
Chandra, RS; Duparc, S; Orazem, J; Robbins, J; Ubben, D; Vandenbroucke, P	1
Kaushik, M; Mahajan, SK; Raina, R; Thakur, P	1
Chandra, R; Mould, DR; Tensfeldt, TG; Zhao, Q	1
Brouwer, KL; Ferslew, BC	1
Holtz, LR; Tarr, PI	1
Claassen, CW; Dzinjalamala, FK; Gilliams, EA; Jumare, J; Laufer, MK; Nyirenda, OM; Plowe, CV; Taylor, T; Thesing, PC; Tracy, LA	1
Chandra, R; Dieng, Y; Djimdé, AA; Dunne, MW; Kain, KC; Mugyenyi, P; Mulenga, M; Oduro, AR; Ogutu, B; Robbins, J; Sagara, I; Sarkar, S; Sie, A; Tiono, AB; Wasunna, M	1
Bardaji, A; Betuela, I; Hanieh, S; Kongs, C; Lufele, E; Menendez, C; Mueller, I; Ome-Kaius, M; Robinson, LJ; Rogerson, SJ; Rosanas-Urgell, A; Samol, P; Schofield, L; Siba, P; Singirok, D; Suen, CS; Sui, D; Umbers, AJ; Unger, HW; Wangnapi, RA; Wapling, J	1
Ansah, P; Chandra, R; Djimde, AA; Ogutu, B; Penali, LK; Robbins, J; Sagara, I; Sie, A; Tiono, AB; Zhao, Q	1
Brown, GV; Hasang, W; Mueller, I; Randall, LM; Rogerson, SJ; Siba, PM; Teo, A; Unger, HW	1
Ayoub, A; Duparc, S; Kamiza, S; Kimani, J; Orrico, R; Phiri, K; Robbins, J; Rojo, R; Vandenbroucke, P	1
Ayoub, A; Duparc, S; Kimani, J; Mtove, GA; Phiri, K; Robbins, J; Rojo, R; Vandenbroucke, P; Zhao, Q	1
Chen, H; Huang, S; Jin, L; Li, J; Ni, Q; Pan, C; Yao, L; Zhang, L	1
Agarwal, P; Anvikar, AR; Pillai, CR; Srivastava, K	1
Juurlink, DN	1
Cutrell, JB; Jodlowski, TZ; Monogue, ML; Sanders, JM	1
Clerc, A; Gendrot, M; Javelle, E; Pradines, B; Savini, H	1
Aajal, A; Ait Brik, A; Ammour, O; Benajiba, C; El Boussadani, B; El Hangouch, J; Oussama, B; Oussama, O; Raissuni, Z; Tahiri, N	1
Abena, PM; Adejumo, P; Bottieau, E; Decloedt, EH; Eholie, SP; Kallay, O; Mills, EJ; Muyembe TamFum, JJ; Nachega, JB; Sam-Agudu, NA; Seydi, M; Suleman, F; Zumla, A	1
Brown, JD; Cicali, B; Henriksen, CH; Sarayani, A	1
Albuquerque, BC; Alexandre, MAA; Baía-da-Silva, D; Balieiro, AAS; Bassat, Q; Borba, MGS; Brito, M; Brito-Sousa, JD; Croda, J; Daniel-Ribeiro, CT; Fontes, CJ; Guerra, MVF; Hajjar, LA; Lacerda, MVG; Melo, GC; Monteiro, WM; Mourão, MPG; Naveca, FG; Nogueira, ML; Pacheco, AGF; Pinto, RC; Romero, GAS; Sampaio, VS; Santos, JDO; Schwarzbold, A; Siqueira, AM; Val, FFA; Xavier, MS	1
Drici, MD; Funck-Brentano, C; Nguyen, LS; Roden, DM; Salem, JE	1
Beldner, S; Chang, D; Chinitz, J; Epstein, LM; Gabriels, J; Goldner, B; Ismail, H; John, R; Mahmood, E; Makker, P; Mansoor, A; Mitra, R; Mountantonakis, S; Saleh, M; Skipitaris, N; Soo Kim, B; Willner, J	1
Becker, G; El-Hage, W; Hingray, C; Javelot, H; Meyer, G; Michel, B	1
Chen, T; Chen, Y; Ferrari, V; Han, Y; Jagasia, D; Kang, Y; Mui, D; Scherrer-Crosbie, M	1
Genoni, G; Kozel, D; Monzani, A; Pistis, G; Scopinaro, A; Secco, GG	1
Seftel, MD	1
Adebayo, AI; Adeoye, AO; Olaoye, IF; Oso, BJ; Tijjani, H	1
Wong, A	1
Thai, TN; Vouri, SM; Winterstein, AG	1
Acunzo, R; Asensio, E; Saad, EB; Sáenz, LC; Uribe, W	1
Abraham, GM; Andrews, R; Bledsoe, TA; Centor, RM; Etxeandia-Ikobaltzeta, I; Forciea, MA; Haeme, R; Humphrey, LL; Jokela, JA; Kansagara, DL; Marcucci, M; Miller, MC; Obley, AJ; Qaseem, A; Yost, J	1
Caceres, SM; Grimm, XA; Malcolm, KC; Nick, JA; Poch, KR; Pohl, K; Rysavy, N; Saavedra, M	1
Azizi, M; Benhaddou, H; El Amrani, R; Elbakkaoui, M; Kamaoui, I; Lahfaoui, M	1
Campos, L; Gouveia, CC	1
Berni-Betancourt, A; Carrasco, OF; Medeiros-Domingo, A	1
Medina, MT; Moncada, SS	1
Abraham, GM; Etxeandia-Ikobaltzeta, I; Forciea, MA; Humphrey, LL; Jokela, JA; Miller, MC; Obley, AJ; Qaseem, A; Yost, J	1
Kazama, I	1
Budnitz, DS; Lovegrove, M; Shehab, N	1
Daily, J; Di Biase, L; Ferrick, KJ; Fisher, JD; Greige, N; Hsia, BC; Khokhar, AS; Krumerman, A; Quiroz, JA	1
Allwood, B; Blockman, M; Decloedt, EH; Koegelenberg, CFN; Parker, A; Reuter, H; Taljaard, J	1
Abi Jaoude, J; El Alam, MB; Garcia Garcia, CJ; Kouzy, R; Ludmir, EB; Taniguchi, CM	1
Acharya, Y; Sultan, S	1
Etxeandia-Ikobaltzeta, I; Humphrey, LL; Qaseem, A; Yost, J	1
Braz, HLB; de Moraes, MEA; Jorge, RJB; Marinho, AD; Monteiro, HSA; Moraes Filho, MO; Silveira, JAM	1
Munic Kos, V; Norgren, K; Norinder, U; Tuck, A	1
Chicharro, P; De Argila, D; Llamas-Velasco, M; Muñoz-Aceituno, E; Muñoz-Hernández, P; Rodríguez-Jiménez, P	1
Czeszko-Paprocka, H; Dyda, T; Horban, A; Kowalska, JD; Pihowicz, A; Podlasin, RB; Thompson, M; Wojtycha-Kwaśnica, B	1
Fiolet, T; Guihur, A; Mahamat-Saleh, Y; Mulot, M; Peiffer-Smadja, N; Rebeaud, ME	2
Calender, A; Israel-Biet, D; Pacheco, Y; Valeyre, D	1
Fatima, S; Fatima, U; Hassan, MI; Rizvi, SSA	1
Antonijević Miljaković, E; Antonijević, B; Baralić, K; Buha Djordjevic, A; Ćurčić, M; Jorgovanović, D; Živančević, K; Đukić-Ćosić, D	1
Bennett, J; Cicatelli, S; DeLuca, J; Duncan, EH; Hamer, M; Hutter, J; Kreishman-Deitrick, M; Lee, C; Livezey, J; Mills, K; Moon, JE; Morrison, M; Oliver, T; Poon, L; Sedegah, M; Selig, D; Sikaffy, A; Sousa, J; Tosh, D; Twomey, P; Vuong, C; Waterman, P	1
Jones, CW; Platts-Mills, TF; Woodford, AL	1
Kim, D; Kim, JH; Kim, JS; Kim, YS; Lee, SY; Yoon, JW; Yu, S	1
Grundmark, B; Vidlin, SH; Watson, S; Zekarias, A	1
Shah, RR	1
Ahuka-Mundeke, S; Bongo-Pasi Nswe, C; Hermans, MP; Ishoso, DK; Kayembe, JM; Kolié, MC; Machekano, RN; Madinga, JN; Mavungu Landu, DJ; Mbala-Kingebeni, P; Mbuyi, GM; Mellors, JW; Mills, EJ; Mofenson, L; Mukeba Tshialala, D; Mukendi, S; Muyembe-Tamfum, JJ; Nachega, JB; Nkwembe, EN; Nsio, JM; Otokoye, JO; Sam-Agudu, NA; Smith, G; Tshiasuma Pipo, M; Zumla, A	1
AlDosary, O; Garbati, MA; Gerberi, D; Kashour, T; Kashour, Z; Murad, MH; Riaz, M; Sohail, MR; Tlayjeh, H; Tleyjeh, IM	1
Alihodžić, S; Angulo-Barturen, I; Banjanac, M; Bencetić Mihaljević, V; Bukvić, M; Eraković Haber, V; Fajdetić, A; Ferrer-Bazaga, S; Gamo, FJ; Gargallo-Viola, D; Herreros, E; Jiménez-Díaz, MB; Kessler, A; Martínez, MS; Mathis, A; Munic Kos, V; Padovan, J; Peric, M; Pešić, D; Spaventi, R	1
Niburski, K; Niburski, O	1
Atakla, HG; Houinato, DS; Noudohounsi, MMUD; Noudohounsi, WC; Sacca, H; Tassiou, NRA	1
Campana, C; Dariolli, R; Gutierrez, A; Irurzun-Arana, I; Pullinger, TK; Sobie, EA; Varshneya, M	1
Ahmed, AAQ; Bakadia, BM; Boni, BO; He, F; Lamboni, L; Mukole, BM; Souho, T; Ullah, MW; Yang, G	1
Almaghraby, A; Beshir, H; Ghazy, RM; Kamal, A; Moursi, A; Ramadan, A; Shaaban, R; Taha, SHN	1
Dingding, Q; Jiangfang, L; Yujia, W; Zequn, Z	1
Costa, KD; Gurung, B; Hajjar, RJ; Li, CM; Li, RA; Lieu, DK; Mak, SY; Tse, WW; Wong, AO; Wong, WS	1
Kepp, O; Kroemer, G; Leduc, M; Liu, P; Martins, I; Tian, AL; Wu, Q; Zhao, L	1
Abi-Gerges, N; Dumotier, B; Ghetti, A; Jordaan, P; Miller, PE; Traebert, M; Urban, L	1
Gómez-Valent, M; Moreno-Ariño, M; Ortonobes Roig, S; Soler-Blanco, N; Torrente Jiménez, I; Van den Eynde Otero, E	1
Brügel, M; Habler, K; Liebchen, U; Paal, M; Scharf, C; Schönermarck, U; Teupser, D; Vogeser, M	1
Ehrlich, H; Elkbuli, A	1
Adjadi, AA; Atakla, HG; Barry, MC; Houinato, AG; Houinato, DS; Noudohounsi, MMUD; Othon, GC; Sacca, H; Salami, AY	1
Brouqui, P; Casalta, JP; Dubourg, G; Jacomo, V; La Scola, B; Lagier, JC; Raoult, D; Rolain, JM	1
Aweeka, F; Gingrich, D; Huang, L; Marzan, F; Sok, V	1
Guo, J; Li, W; Szendrey, M; Yang, T; Zhang, S	1
Brañez-Condorena, A; Diaz-Arocutipa, C; Hernandez, AV	1
Saint-Gerons, DM; Tabarés-Seisdedos, R	1
Chi, G; Fitzgerald, C; Gibson, CM; Kazmi, SHA; Lee, JJ; Memar Montazerin, S; Shojaei, F	1
Heitmann, S; Hill, AP; Kerr, N; Mangala, M; McArthur, JR; Perry, MD; TeBay, C; Vandenberg, JI; Windley, MJ	1
Barry, H; Boly, R; Diendéré, AE; Drabo, MK; Ouédraogo, AR; Ouedraogo, AS; Ouédraogo, E; Poda, A; Rouamba, T; Sondo, A; Tahita, MC; Tarnagda, Z; Tinto, H; Traoré, I; Valea, I; Yaméogo, NV; Zoungrana, J	1
Chotsiri, P; Hoglund, RM; Tarning, J; Watson, JA; White, NJ	1
Beeson, JG; Burns, AL; Creek, DJ; Frölich, S; Gancheva, M; Goodman, CD; Ma, S; McFadden, GI; McLean, KT; O'Handley, R; Siddiqui, G; Sleebs, BE; Venter, H; Wilson, DW	1
Giarolla, J; Parise-Filho, R; Polli, MC; Vassiliades, SV; Vaz, ES	1
Aït Moussa, L; Alj, L; Khattabi, A; Meski, FZ; Sefiani, H; Soulaymani Bencheikh, R; Tebaa, A	1
Aguiar, FC; Aguiar, RLO; Anschau, F; Bartolazzi, F; Batista, JDL; Bicalho, MAC; Costa, FR; Ferreira, MAP; Guimarães-Júnior, MH; Machado-Rugolo, J; Manenti, ERF; Marcolino, MS; Menezes, LSM; Nascimento, GF; Nogueira, MCA; Oliveira, LS; Pereira, DN; Pereira, EC; Pires, MC; Polanczyk, CA; Rios, DRA; Ruschel, KB; Schwarzbold, AV; Souza-Silva, MVR; Tofani, MGT; Vasconcelos, DH; Vasconcelos, IM; Vianna, HR; Ziegelmann, PK	1

Reviews

27 review(s) available for chloroquine and zithromax

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jul-15, Volume: 33, Issue:2 Topics: Animals; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Resistance; Health Planning Guidelines; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Primaquine; Proguanil	2001
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy. Malaria journal, 2008, Dec-16, Volume: 7 Topics: Africa South of the Sahara; Animals; Antimalarials; Azithromycin; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic	2008
Azithromycin for treating uncomplicated malaria. The Cochrane database of systematic reviews, 2011, Feb-16, Issue:2 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Azithromycin; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Proguanil; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Treatment Failure	2011
Azithromycin plus chloroquine: combination therapy for protection against malaria and sexually transmitted infections in pregnancy. Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:9 Topics: Adult; Anti-Bacterial Agents; Antimalarials; Azithromycin; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Infectious; Sexually Transmitted Diseases	2011
Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Apr-27, Volume: 192, Issue:17 Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Monitoring, Physiologic; Pandemics; Patient Selection; Pneumonia, Viral; SARS-CoV-2	2020
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review. JAMA, 2020, May-12, Volume: 323, Issue:18 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Immunoglobulins; Immunologic Factors; Indoles; Lopinavir; Oseltamivir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Withholding Treatment	2020
[COVID-19 pandemia: Impact on the cariovascular system. Data of 1 Annales de cardiologie et d'angeiologie, 2020, Volume: 69, Issue:3 Topics: Antimalarials; Antiviral Agents; Azithromycin; Betacoronavirus; Cardiomyopathies; Cardiovascular Diseases; Cerebrovascular Disorders; Chloroquine; Comorbidity; Coronary Disease; Coronavirus Infections; COVID-19; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylprednisolone; Pandemics; Pneumonia, Viral; Risk Factors; SARS-CoV-2; Virus Internalization	2020
Cardiovascular manifestations and treatment considerations in COVID-19. Heart (British Cardiac Society), 2020, Volume: 106, Issue:15 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Azithromycin; Betacoronavirus; Biomarkers; Cardiovascular Diseases; Chloroquine; Comorbidity; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Disseminated Intravascular Coagulation; Extracorporeal Membrane Oxygenation; Humans; Hydroxychloroquine; Immunosuppressive Agents; Influenza, Human; Lung; Myocardium; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; SARS-CoV-2; Severe Acute Respiratory Syndrome; Troponin; Venous Thromboembolism	2020
Recommendations for the measurement of the QT interval during the use of drugs for COVID-19 infection treatment. Updatable in accordance with the availability of new evidence. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020, Volume: 59, Issue:2 Topics: Adult; Aged; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Hydroxychloroquine; Incidence; Long QT Syndrome; Male; Middle Aged; Pandemics; Pneumonia, Viral; Practice Guidelines as Topic; Prognosis; Risk Assessment	2020
Coronavirus Disease 2019: Clinical Review. Acta medica portuguesa, 2020, Jul-01, Volume: 33, Issue:7-8 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Azithromycin; Betacoronavirus; Blood Coagulation Disorders; China; Chiroptera; Chloroquine; Coronavirus Infections; COVID-19; Glucocorticoids; Humans; Hydroxychloroquine; Infectious Disease Incubation Period; Lopinavir; Lung; Pandemics; Pneumonia, Viral; Prognosis; Pyrazines; Radiography, Thoracic; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; Symptom Assessment	2020
Targeting lymphocyte Kv1.3-channels to suppress cytokine storm in severe COVID-19: Can it be a novel therapeutic strategy? Drug discoveries & therapeutics, 2020, Jul-15, Volume: 14, Issue:3 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Cytokines; Drug Delivery Systems; Humans; Kv1.3 Potassium Channel; Lymphocytes; Pandemics; Pneumonia, Viral; SARS-CoV-2; Severity of Illness Index	2020
Characteristics of the Multiplicity of Randomized Clinical Trials for Coronavirus Disease 2019 Launched During the Pandemic. JAMA network open, 2020, 07-01, Volume: 3, Issue:7 Topics: Adenosine Monophosphate; Alanine; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antimalarials; Antiviral Agents; Azithromycin; Betacoronavirus; Biological Products; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; Humans; Hydroxychloroquine; Immunization, Passive; Non-Randomized Controlled Trials as Topic; Pandemics; Pneumonia, Viral; Protease Inhibitors; Protein-Tyrosine Kinases; Randomized Controlled Trials as Topic; Respiration, Artificial; SARS-CoV-2; Viral Load	2020
Antimalarial and cytotoxic drugs on COVID-19 and the cardiovascular burden: Literature review and lessons to be learned. Vascular, 2021, Volume: 29, Issue:2 Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Azithromycin; Cardiovascular Diseases; Chemically-Induced Disorders; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Humans; SARS-CoV-2	2021
Existing highly accumulating lysosomotropic drugs with potential for repurposing to target COVID-19. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 130 Topics: Anti-Inflammatory Agents; Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chemical and Drug Induced Liver Injury; Chloroquine; Computer Simulation; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; Endosomes; Humans; Hydrogen-Ion Concentration; Hydroxychloroquine; Intracellular Membranes; Lysosomes; Membrane Lipids; Models, Biological; Pandemics; Phospholipids; Pneumonia, Viral; SARS-CoV-2; Surface-Active Agents; Virus Internalization	2020
Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2021, Volume: 27, Issue:1 Topics: Antiviral Agents; Azithromycin; Bayes Theorem; Bias; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Hydroxychloroquine; Risk; SARS-CoV-2; Standard of Care; Survival Analysis	2021
Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis. Trends in immunology, 2020, Volume: 41, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Autophagy; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Host-Pathogen Interactions; Humans; Isoniazid; Lung; Pandemics; Pneumonia, Viral; Pulmonary Edema; Rifampin; Sarcoidosis; SARS-CoV-2; Severe Acute Respiratory Syndrome; Severity of Illness Index	2020
Impact of Hydroxychloroquine/Chloroquine in COVID-19 Therapy: Two Sides of the Coin. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2020, Volume: 40, Issue:10 Topics: Anti-Infective Agents; Azithromycin; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Drug Synergism; Humans; Hydroxychloroquine; Immunologic Factors; Pandemics; Pneumonia, Viral; SARS-CoV-2; Treatment Outcome	2020
Chloroquine and hydroxychloroquine for COVID-19: Perspectives on their failure in repurposing. Journal of clinical pharmacy and therapeutics, 2021, Volume: 46, Issue:1 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Repositioning; Humans; Hydroxychloroquine; Long QT Syndrome; Treatment Outcome; Viral Load	2021
Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis. The Journal of antimicrobial chemotherapy, 2021, 01-01, Volume: 76, Issue:1 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Hospitalization; Humans; Hydroxychloroquine; Randomized Controlled Trials as Topic; Treatment Outcome	2021
Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients: authors' response. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2021, Volume: 27, Issue:1 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Humans; Hydroxychloroquine; SARS-CoV-2; Treatment Outcome	2021
Prevention and treatment of COVID-19: Focus on interferons, chloroquine/hydroxychloroquine, azithromycin, and vaccine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Vaccines; Humans; Hydroxychloroquine; Interferons; Treatment Outcome	2021
A systematic review and meta-analysis on chloroquine and hydroxychloroquine as monotherapy or combined with azithromycin in COVID-19 treatment. Scientific reports, 2020, 12-17, Volume: 10, Issue:1 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; SARS-CoV-2; Treatment Outcome	2020
Off-label use of chloroquine, hydroxychloroquine, azithromycin and lopinavir/ritonavir in COVID-19 risks prolonging the QT interval by targeting the hERG channel. European journal of pharmacology, 2021, Feb-15, Volume: 893 Topics: Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Combinations; ERG1 Potassium Channel; Humans; Hydroxychloroquine; Long QT Syndrome; Lopinavir; Off-Label Use; Ritonavir	2021
QTc prolongation in COVID-19 patients treated with hydroxychloroquine, chloroquine, azithromycin, or lopinavir/ritonavir: A systematic review and meta-analysis. Pharmacoepidemiology and drug safety, 2021, Volume: 30, Issue:6 Topics: Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Long QT Syndrome; Lopinavir; Observational Studies as Topic; Ritonavir	2021
Effect of azithromycin and hydroxychloroquine in patients hospitalized with COVID-19: Network meta-analysis of randomized controlled trials. Journal of medical virology, 2021, Volume: 93, Issue:12 Topics: Adult; Aged; Antiviral Agents; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Network Meta-Analysis; Randomized Controlled Trials as Topic; Respiration, Artificial	2021
Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies. European journal of clinical pharmacology, 2023, Volume: 79, Issue:6 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; Dexamethasone; Drug Repositioning; Humans; Hydroxychloroquine; Ivermectin; Methylprednisolone; Pandemics; Reproducibility of Results; SARS-CoV-2	2023

Trials

16 trial(s) available for chloroquine and zithromax

Article	Year
Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. Lancet (London, England), 1994, Jun-04, Volume: 343, Issue:8910 Topics: Administration, Oral; Adolescent; Adult; Azithromycin; Chloroquine; Drug Administration Schedule; Drug Resistance; Humans; Malaria, Falciparum; Pilot Projects	1994
A multicenter study of azithromycin, alone and in combination with chloroquine, for the treatment of acute uncomplicated Plasmodium falciparum malaria in India. The Journal of infectious diseases, 2005, May-15, Volume: 191, Issue:10 Topics: Adolescent; Adult; Aged; Antimalarials; Azithromycin; Chloroquine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; India; Malaria, Falciparum; Male; Middle Aged	2005
A double-blind, randomized study of azithromycin compared to chloroquine for the treatment of Plasmodium vivax malaria in India. The American journal of tropical medicine and hygiene, 2005, Volume: 73, Issue:6 Topics: Adult; Aged; Animals; Antimalarials; Azithromycin; Chloroquine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Malaria, Vivax; Male; Middle Aged; Parasitemia; Plasmodium vivax; Primaquine; Treatment Outcome	2005
Lack of a pharmacokinetic interaction between azithromycin and chloroquine. The American journal of tropical medicine and hygiene, 2006, Volume: 74, Issue:3 Topics: Adult; Animals; Antimalarials; Area Under Curve; Azithromycin; Chloroquine; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Male; Middle Aged	2006
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria. PloS one, 2012, Volume: 7, Issue:8 Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Genotyping Techniques; Humans; Infant; Longitudinal Studies; Malaria; Male; Proguanil	2012
Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa. Malaria journal, 2013, Apr-11, Volume: 12 Topics: Africa; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious	2013
Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed-dose azithromycin and chloroquine combination tablets. Malaria journal, 2014, Jan-29, Volume: 13 Topics: Adolescent; Adult; Africa South of the Sahara; Antimalarials; Azithromycin; Biological Availability; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Tablets; United States	2014
Chloroquine-azithromycin combination antimalarial treatment decreases risk of respiratory- and gastrointestinal-tract infections in Malawian children. The Journal of infectious diseases, 2014, Aug-15, Volume: 210, Issue:4 Topics: Antimalarials; Azithromycin; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Incidence; Longitudinal Studies; Malaria; Malawi; Male; Respiratory Tract Infections; Risk	2014
Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults. Malaria journal, 2014, Nov-25, Volume: 13 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Azithromycin; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Treatment Outcome; Uganda; Young Adult; Zambia	2014
Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial. BMC medicine, 2015, Jan-16, Volume: 13 Topics: Adult; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria; Papua New Guinea; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Single-Blind Method; Sulfadoxine; Young Adult	2015
Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study. Malaria journal, 2015, Mar-10, Volume: 14 Topics: Africa South of the Sahara; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Azithromycin; Child; Child, Preschool; Chloroquine; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male	2015
Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission. Malaria journal, 2015, May-26, Volume: 14 Topics: Adult; Antibodies, Protozoan; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Erythrocytes; Female; Humans; Malaria, Falciparum; Papua New Guinea; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Young Adult	2015
Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial. PloS one, 2016, Volume: 11, Issue:6 Topics: Adolescent; Adult; Azithromycin; Chloroquine; Drug Combinations; Female; Humans; Infant, Newborn; Intention to Treat Analysis; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult	2016
Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa. PloS one, 2016, Volume: 11, Issue:11 Topics: Adolescent; Adult; Africa South of the Sahara; Asymptomatic Diseases; Azithromycin; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Parasite Load; Parasitemia; Plasmodium falciparum; Pregnancy; Treatment Outcome; Young Adult	2016
Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial. JAMA network open, 2020, 04-24, Volume: 3, Issue:4 Topics: Adult; Aged; Anti-Bacterial Agents; Antiviral Agents; Azithromycin; Betacoronavirus; Brazil; Chloroquine; Coronavirus Infections; COVID-19; Disease Outbreaks; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oseltamivir; Pandemics; Pneumonia, Viral; SARS-CoV-2; Tertiary Care Centers	2020
An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria inf Malaria journal, 2020, Sep-16, Volume: 19, Issue:1 Topics: Adult; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Young Adult	2020

Other Studies

90 other study(ies) available for chloroquine and zithromax

Article	Year
In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. The Journal of biological chemistry, 2007, Jan-26, Volume: 282, Issue:4 Topics: Amodiaquine; Animals; Antimalarials; Azithromycin; DNA, Protozoan; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Models, Structural; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins	2007
In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Azithromycin; Clinical Trials, Phase II as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes	2007
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Animals; Antimalarials; Benzothiazoles; Diamines; Drug Evaluation, Preclinical; Erythrocytes; Fluorescent Dyes; Humans; Hypoxanthine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Reproducibility of Results; Sensitivity and Specificity	2007
Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Drug Resistance; Flow Cytometry; Green Fluorescent Proteins; Plasmodium falciparum; Protein Synthesis Inhibitors; Topoisomerase II Inhibitors	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Antimalarial activity of tigecycline, a novel glycylcycline antibiotic. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Inhibitory Concentration 50; Minocycline; Parasitic Sensitivity Tests; Plasmodium falciparum; Tetracycline; Tetracyclines; Tigecycline	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics. Bioorganic & medicinal chemistry, 2011, Mar-01, Volume: 19, Issue:5 Topics: Antimalarials; Automation; Azithromycin; Drug Resistance, Multiple; Inhibitory Concentration 50; Macrolides; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Thiourea; Urea	2011
Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. Journal of medicinal chemistry, 2012, Feb-09, Volume: 55, Issue:3 Topics: Amides; Amines; Aminoquinolines; Animals; Antimalarials; Azithromycin; Cell Line, Tumor; Drug Resistance; Erythromycin; Humans; Macrolides; Malaria; Male; Mice; Microsomes, Liver; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship	2012
Novel hybrid molecules based on 15-membered azalide as potential antimalarial agents. European journal of medicinal chemistry, 2012, Volume: 49 Topics: Aminoquinolines; Antimalarials; Azithromycin; Cell Line; Chloroquine; Humans; Macrolides; Malaria; Plasmodium falciparum	2012
Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7 Topics: Anti-Bacterial Agents; Antimalarials; Aza Compounds; Cell Line, Tumor; Chloroquine; Drug Resistance; Erythromycin; Gram-Positive Bacteria; Humans; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Antimalarial activities of 6-iodouridine and its prodrugs and potential for combination therapy. Journal of medicinal chemistry, 2013, Mar-28, Volume: 56, Issue:6 Topics: Animals; Antimalarials; CHO Cells; Cricetinae; Cricetulus; Drug Interactions; Drug Resistance; Female; Mice; Orotidine-5'-Phosphate Decarboxylase; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Uridine	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature, 2020, Volume: 583, Issue:7816 Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins	2020
Chloroquine fumardiamides as novel quorum sensing inhibitors. Bioorganic & medicinal chemistry letters, 2020, 08-15, Volume: 30, Issue:16 Topics: Amides; Anti-Bacterial Agents; Chloroquine; Chromobacterium; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Quorum Sensing; Structure-Activity Relationship	2020
Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:3 Topics: Animals; Antiprotozoal Agents; Azithromycin; Chloroquine; Drug Interactions; Drug Resistance; Erythromycin; Plasmodium falciparum	1992
Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:1 Topics: Animals; Antiprotozoal Agents; Azithromycin; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Erythromycin; Malaria; Male; Mice; Plasmodium berghei; Specific Pathogen-Free Organisms	1993
Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:10 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthoquinones; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Risk Assessment	1998
Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. Experimental parasitology, 2000, Volume: 94, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Azithromycin; Chloroquine; Doxycycline; Erythromycin; Female; Macaca mulatta; Malaria; Male; Mice; Parasitemia; Plasmodium cynomolgi; Plasmodium yoelii; Primaquine; Pyrimethamine	2000
Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin. Pharmaceutical research, 2003, Volume: 20, Issue:4 Topics: Ampicillin; Azithromycin; Cell Culture Techniques; Cell Membrane; Chloroquine; Lysosomes; Macrophages; Models, Biological; Phthalimides; Pivampicillin	2003
Azithromycin/chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig. The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:5 Topics: Action Potentials; Anesthesia; Animals; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Blood Pressure; Chloroquine; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Rate; Male	2007
Lysosomotropic drugs inhibit maturation of transforming growth factor-beta. Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:9 Topics: Amodiaquine; Animals; Azithromycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Cell Line; Cell Line, Tumor; Chloroquine; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Furin; Humans; Hydroxychloroquine; Kinetics; Lysosomes; Mice; Mice, Inbred C57BL; Phosphorylation; Stem Cells; Transforming Growth Factor beta	2008
Pharmacokinetic properties of azithromycin in pregnancy. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Adult; Antimalarials; Area Under Curve; Azithromycin; Chloroquine; Chromatography, High Pressure Liquid; Drug Combinations; Female; Half-Life; Humans; Intestinal Absorption; Models, Statistical; Papua New Guinea; Pregnancy; Pyrimethamine; Sulfadoxine; Tandem Mass Spectrometry; Young Adult	2010
Quinine for the treatment of malaria in pregnancy. The Lancet. Infectious diseases, 2010, Volume: 10, Issue:3 Topics: Animals; Antimalarials; Azithromycin; Chloroquine; Clindamycin; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Quinine	2010
In vivo and in vitro antimalarial properties of azithromycin-chloroquine combinations that include the resistance reversal agent amlodipine. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7 Topics: Amlodipine; Animals; Antimalarials; Azithromycin; Chloroquine; Drug Interactions; Female; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum	2011
Comparative efficacy of pre-erythrocytic whole organism vaccine strategies against the malaria parasite. Vaccine, 2011, Sep-16, Volume: 29, Issue:40 Topics: Animals; Azithromycin; CD8-Positive T-Lymphocytes; Chloroquine; Erythrocytes; Female; Liver; Malaria; Malaria Vaccines; Mice; Mice, Inbred C57BL; Parasite Load; Parasitemia; Plasmodium berghei; Sporozoites; Vaccination; Vaccines, Attenuated	2011
In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. The Journal of antibiotics, 2012, Volume: 65, Issue:12 Topics: Antimalarials; Azithromycin; Chloroquine; Drug Delivery Systems; Drug Resistance; Erythromycin; Inhibitory Concentration 50; Lipids; Particle Size; Plasmodium falciparum; Solubility; Time Factors	2012
Impairment of lysosomal functions by azithromycin and chloroquine contributes to anti-inflammatory phenotype. Cellular immunology, 2012, Volume: 279, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Azithromycin; Blotting, Western; Cell Line; Cell Survival; Chloroquine; Dinoprostone; Enzyme Inhibitors; Flow Cytometry; Hydrogen-Ion Concentration; Interleukin-6; Lipopolysaccharides; Lysosomes; Macrolides; Macrophages; Mice; Microscopy, Confocal; Proton-Translocating ATPases; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha	2012
Chemobiosynthesis of new antimalarial macrolides. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Antimalarials; Azithromycin; Chloroquine; Drug Resistance; Erythromycin; Macrolides; Malaria; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum	2013
Scrub typhus and malaria co-infection causing severe sepsis. Tropical doctor, 2014, Volume: 44, Issue:1 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Chloroquine; Coinfection; Doxycycline; Enzyme-Linked Immunosorbent Assay; Female; Fever; Humans; Immunoglobulin M; Malaria; Middle Aged; Norepinephrine; Orientia tsutsugamushi; Plasmodium vivax; Scrub Typhus; Sepsis; Severity of Illness Index; Treatment Outcome	2014
Identification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substrates. Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 139, Issue:1 Topics: Amiodarone; Animals; Anions; Azithromycin; Biliary Tract; Cells, Cultured; Chloroquine; Desipramine; Fluorobenzenes; Gentamicins; Hepatocytes; Male; Models, Biological; Phospholipids; Pyrimidines; Rats; Rats, Wistar; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid	2014
Unexplained benefits of antibiotics in childhood: empiricism in need of enlightenment. The Journal of infectious diseases, 2014, Aug-15, Volume: 210, Issue:4 Topics: Antimalarials; Azithromycin; Chloroquine; Female; Gastrointestinal Diseases; Humans; Malaria; Male; Respiratory Tract Infections	2014
Human babesiosis in Southeast China: A case report. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2018, Volume: 68 Topics: Administration, Intravenous; Anemia, Hemolytic; Anti-Bacterial Agents; Azithromycin; Babesiosis; C-Reactive Protein; China; Chloroquine; Clindamycin; Female; Fever; Humans; Middle Aged; Neutropenia; Thrombocytopenia	2018
The Indian journal of medical research, 2017, Volume: 146, Issue:5 Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines	2017
Chloroquine as a prophylactic agent against COVID-19? International journal of antimicrobial agents, 2020, Volume: 55, Issue:6 Topics: Animals; Antimalarials; Antiviral Agents; Azithromycin; Betacoronavirus; Chlorocebus aethiops; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; Pre-Exposure Prophylaxis; SARS-CoV-2; Vero Cells	2020
Chloroquine and Hydroxychloroquine for the Prevention or Treatment of COVID-19 in Africa: Caution for Inappropriate Off-label Use in Healthcare Settings. The American journal of tropical medicine and hygiene, 2020, Volume: 102, Issue:6 Topics: Antimalarials; Antirheumatic Agents; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Testing; Drug Repositioning; Humans; Hydroxychloroquine; Off-Label Use; Pandemics; Pneumonia, Viral; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Sample Size; SARS-CoV-2; Treatment Outcome; United States	2020
Some drugs for COVID-19. The Medical letter on drugs and therapeutics, 2020, 04-06, Volume: 62, Issue:1595 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Combinations; Drug Repositioning; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Neuraminidase; Pandemics; Pneumonia, Viral; Ritonavir; SARS-CoV-2	2020
Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine. Research in social & administrative pharmacy : RSAP, 2021, Volume: 17, Issue:2 Topics: Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxychloroquine; Long QT Syndrome; Pharmacovigilance; Torsades de Pointes; United States	2021
Response to the editorial "COVID-19 in patients with cardiovascular diseases": Covid-19 treatment with hydroxychloroquine or chloroquine and azithromycin: A potential risk of Torsades de Pointes. Archives of cardiovascular diseases, 2020, Volume: 113, Issue:5 Topics: Azithromycin; Betacoronavirus; Cardiovascular Diseases; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; SARS-CoV-2; Torsades de Pointes	2020
Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection. Circulation. Arrhythmia and electrophysiology, 2020, Volume: 13, Issue:6 Topics: Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Drug Therapy, Combination; Electrocardiography; Follow-Up Studies; Humans; Hydroxychloroquine; Incidence; Pandemics; Pneumonia, Viral; Prospective Studies; Risk Factors; SARS-CoV-2; United States	2020
COVID-19 and (hydroxy)chloroquine-azithromycin combination: Should we take the risk for our patients? British journal of clinical pharmacology, 2020, Volume: 86, Issue:6 Topics: Azithromycin; Chloroquine; Coronavirus Infections; COVID-19; Drug Therapy, Combination; Humans; Hydroxychloroquine; Long QT Syndrome; Mental Disorders; Pandemics; Pneumonia, Viral; Risk Factors	2020
QTc evaluation in COVID-19 patients treated with chloroquine/hydroxychloroquine. European journal of clinical investigation, 2020, Volume: 50, Issue:6 Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Cardiotoxicity; Chloroquine; Coronavirus Infections; COVID-19; Dehydration; Drug Interactions; Electrocardiography; Humans; Hydroxychloroquine; Long QT Syndrome; Pandemics; Pneumonia, Viral; Risk Assessment; Water-Electrolyte Imbalance	2020
Additional safety consideration for azithromycin in the management of SARS-CoV-2 infection. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, 05-04, Volume: 192, Issue:18 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Hydroxychloroquine; Pandemics; Pneumonia, Viral; SARS-CoV-2	2020
Repurposing of chloroquine and some clinically approved antiviral drugs as effective therapeutics to prevent cellular entry and replication of coronavirus. Journal of biomolecular structure & dynamics, 2021, Volume: 39, Issue:10 Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Azithromycin; Chloroquine; Drug Repositioning; Humans; Lopinavir; Molecular Docking Simulation; Severe acute respiratory syndrome-related coronavirus; Virus Internalization; Virus Replication	2021
COVID-19 and toxicity from potential treatments: Panacea or poison. Emergency medicine Australasia : EMA, 2020, Volume: 32, Issue:4 Topics: Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; Randomized Controlled Trials as Topic; SARS-CoV-2; Treatment Outcome	2020
An evaluation of co-use of chloroquine or hydroxychloroquine plus azithromycin on cardiac outcomes: A pharmacoepidemiological study to inform use during the COVID19 pandemic. Research in social & administrative pharmacy : RSAP, 2021, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Azithromycin; Chloroquine; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Female; Heart Diseases; Humans; Hydroxychloroquine; Male; Middle Aged; Pharmacoepidemiology; Retrospective Studies; Risk Factors; Young Adult	2021
Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? Living Practice Points From the American College of Physicians (Version 1). Annals of internal medicine, 2020, 07-21, Volume: 173, Issue:2 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; SARS-CoV-2; United States	2020
Mycobacterium abscessus Clearance by Neutrophils Is Independent of Autophagy. Infection and immunity, 2020, 07-21, Volume: 88, Issue:8 Topics: Adaptor Proteins, Signal Transducing; Anti-Bacterial Agents; Autophagy; Azithromycin; Case-Control Studies; Chemokine CCL4; Chloroquine; Cystic Fibrosis; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Immunosuppressive Agents; Interleukin-8; Mycobacterium abscessus; Neutrophils; Phagocytosis; Primary Cell Culture; Reactive Oxygen Species; Signal Transduction; Sirolimus; Wortmannin	2020
[Acute respiratory distress syndrome secondary to SARS-CoV-2 infection in an infant]. Revue des maladies respiratoires, 2020, Volume: 37, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Azithromycin; Betacoronavirus; Chloroquine; Combined Modality Therapy; Coronavirus Infections; COVID-19; Fatal Outcome; Female; Humans; Infant; Morocco; Multiple Organ Failure; Nasopharynx; Pandemics; Pneumonia, Viral; Respiration, Artificial; Respiratory Distress Syndrome; SARS-CoV-2; Tomography, X-Ray Computed	2020
Potential pro-arrhythmic effects of pharmacotherapy against SARS-CoV-2. Archivos de cardiologia de Mexico, 2020, Volume: 90, Issue:Supl Topics: Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral	2020
Hydroxychloroquine/ chloroquine as a treatment choice or prophylaxis for Covid-19 at the primary care level in developing countries: A Primum non Nocere dilemma. Journal of the neurological sciences, 2020, 08-15, Volume: 415 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Developing Countries; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; Primary Health Care; SARS-CoV-2	2020
Update Alert: Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? Living Practice Points From the American College of Physicians. Annals of internal medicine, 2020, 07-21, Volume: 173, Issue:2 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; SARS-CoV-2; United States	2020
US Hydroxychloroquine, Chloroquine, and Azithromycin Outpatient Prescription Trends, October 2019 Through March 2020. JAMA internal medicine, 2020, 10-01, Volume: 180, Issue:10 Topics: Anti-Infective Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Databases, Pharmaceutical; Drug Prescriptions; Humans; Hydroxychloroquine; Outpatients; Pandemics; Pneumonia, Viral; Practice Patterns, Physicians'; Pre-Exposure Prophylaxis; Prescription Drug Monitoring Programs; SARS-CoV-2; United States	2020
QT prolongation in a diverse, urban population of COVID-19 patients treated with hydroxychloroquine, chloroquine, or azithromycin. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020, Volume: 59, Issue:2 Topics: Age Distribution; Aged; Aged, 80 and over; Antimalarials; Azithromycin; Chloroquine; Coronavirus Infections; COVID-19; Electrocardiography; Female; Follow-Up Studies; Hospitalization; Humans; Hydroxychloroquine; Incidence; Long QT Syndrome; Male; Middle Aged; Pandemics; Pneumonia, Viral; Risk Assessment; Sex Distribution; Urban Population	2020
Benefit v. risk when using chloroquine in patients with severe COVID-19 disease. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020, 04-02, Volume: 110, Issue:5 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; SARS-CoV-2	2020
Update Alert 2: Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? Living Practice Points From the American College of Physicians. Annals of internal medicine, 2020, 09-01, Volume: 173, Issue:5 Topics: Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Pandemics; Pneumonia, Viral; SARS-CoV-2; United States	2020
In silico study of azithromycin, chloroquine and hydroxychloroquine and their potential mechanisms of action against SARS-CoV-2 infection. International journal of antimicrobial agents, 2020, Volume: 56, Issue:3 Topics: Amino Acid Motifs; Angiotensin-Converting Enzyme 2; Antiviral Agents; Azithromycin; Betacoronavirus; Binding Sites; Cathepsin L; Chloroquine; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; Cysteine Endopeptidases; Host-Pathogen Interactions; Humans; Hydroxychloroquine; Molecular Docking Simulation; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Thermodynamics; Viral Nonstructural Proteins; Virus Attachment	2020
SDRIFE-like rash associated with COVID-19, clinicopathological correlation. The Australasian journal of dermatology, 2021, Volume: 62, Issue:1 Topics: Aged; Antiviral Agents; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Drug Eruptions; Exanthema; Female; Humans; Hydroxychloroquine	2021
How to follow-up a patient who received tocilizumab in severe COVID-19: a case report. European journal of medical research, 2020, Aug-27, Volume: 25, Issue:1 Topics: Adult; Antibodies, Monoclonal, Humanized; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cytokines; Humans; Inflammation; Male; Off-Label Use; Pandemics; Pneumonia, Viral; Poland; SARS-CoV-2; Tomography, X-Ray Computed	2020
Safety assessment of drug combinations used in COVID-19 treatment: in silico toxicogenomic data-mining approach. Toxicology and applied pharmacology, 2020, 11-01, Volume: 406 Topics: Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Computer Simulation; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Data Mining; Databases, Genetic; Drug Therapy, Combination; Gene Regulatory Networks; Humans; Hydroxychloroquine; Lopinavir; Pandemics; Pneumonia, Viral; Ritonavir; SARS-CoV-2; Toxicogenetics	2020
Characteristics of COVID-19 clinical trials registered with ClinicalTrials.gov: cross-sectional analysis. BMJ open, 2020, 09-17, Volume: 10, Issue:9 Topics: Antibodies, Monoclonal, Humanized; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Double-Blind Method; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Pandemics; Pneumonia, Viral; Registries; Ritonavir; SARS-CoV-2; Single-Blind Method; Stem Cell Transplantation	2020
Cardiotoxicity induced by the combination therapy of chloroquine and azithromycin in human embryonic stem cell-derived cardiomyocytes. BMB reports, 2020, Volume: 53, Issue:10 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Azithromycin; Cardiotoxicity; Cell Differentiation; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Embryonic Stem Cells; Humans; Mice; Myocytes, Cardiac; Pandemics; Pneumonia, Viral	2020
Sex Differences in Reported Adverse Drug Reactions to COVID-19 Drugs in a Global Database of Individual Case Safety Reports. Drug safety, 2020, Volume: 43, Issue:12 Topics: Abdominal Pain; Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azithromycin; Chemical and Drug Induced Liver Injury; Chloroquine; COVID-19 Drug Treatment; Databases, Pharmaceutical; Diarrhea; Drug Combinations; Drug Eruptions; Drug Repositioning; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxychloroquine; Long QT Syndrome; Lopinavir; Male; Nausea; Oseltamivir; Ritonavir; Sex Distribution; Sex Factors; Vomiting	2020
Clinical Characteristics and Outcomes of Patients Hospitalized for COVID-19 in Africa: Early Insights from the Democratic Republic of the Congo. The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:6 Topics: Adolescent; Adult; Asymptomatic Diseases; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Democratic Republic of the Congo; Drug Combinations; Enoxaparin; Female; Hospital Mortality; Hospitalization; Hospitals; Humans; Intensive Care Units; Lopinavir; Male; Middle Aged; Obesity; Pandemics; Patient Discharge; Renal Insufficiency, Chronic; Retrospective Studies; Risk Factors; Ritonavir; SARS-CoV-2; Severity of Illness Index; Treatment Outcome	2020
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides. British journal of pharmacology, 2021, Volume: 178, Issue:2 Topics: Animals; Antimalarials; Azithromycin; Chloroquine; Dogs; Malaria; Mice; Plasmodium falciparum; Rats	2021
Impact of Trump's Promotion of Unproven COVID-19 Treatments and Subsequent Internet Trends: Observational Study. Journal of medical Internet research, 2020, 11-20, Volume: 22, Issue:11 Topics: Adenosine Monophosphate; Alanine; Azithromycin; Chloroquine; Communication; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Federal Government; Fraud; Humans; Hydroxychloroquine; Internet; Language; Mass Media; Pandemics; Pneumonia, Viral; Public Health; United States	2020
Acute Guillain-Barré polyradiculoneuritis indicative of COVID-19 infection: a case report. The Pan African medical journal, 2020, Volume: 35, Issue:Suppl 2 Topics: Adult; Atrial Fibrillation; Azithromycin; Betacoronavirus; Chloroquine; Clinical Laboratory Techniques; Combined Modality Therapy; Contraindications, Drug; Coronavirus Infections; COVID-19; COVID-19 Testing; Early Diagnosis; Guillain-Barre Syndrome; Humans; Male; Muscle Weakness; Nasopharynx; Olfaction Disorders; Oxygen Inhalation Therapy; Pandemics; Pneumonia, Viral; Quadriplegia; Respiration, Artificial; SARS-CoV-2; Urinary Incontinence	2020
Investigational Treatments for COVID-19 may Increase Ventricular Arrhythmia Risk Through Drug Interactions. CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:2 Topics: Action Potentials; Antiviral Agents; Arrhythmias, Cardiac; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lopinavir; Male; Models, Theoretical; Myocytes, Cardiac; Risk Factors; Ritonavir; Therapies, Investigational	2021
Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues. Journal of molecular and cellular cardiology, 2021, Volume: 153 Topics: Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Drug-Related Side Effects and Adverse Reactions; Humans; Myocardial Contraction; Myocytes, Cardiac; Pluripotent Stem Cells; Tissue Engineering; Ventricular Function	2021
Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response. Cell death & disease, 2021, 01-06, Volume: 12, Issue:1 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Chloroquine; Humans; Hydroxychloroquine; Mice	2021
Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in Adult Human Primary Cardiomyocytes. Toxicological sciences : an official journal of the Society of Toxicology, 2021, 04-12, Volume: 180, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Azithromycin; Cardiotoxicity; Chloroquine; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Myocytes, Cardiac; Risk Assessment; SARS-CoV-2; United States	2021
[Clinical and pharmacological data in COVID-19 hospitalized nonagenarian patients]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2021, Volume: 34, Issue:2 Topics: Aged, 80 and over; Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Female; Hospitalization; Humans; Hydroxychloroquine; Male; Physical Functional Performance; Polypharmacy; Retrospective Studies; Risk Factors; Treatment Outcome	2021
Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum Journal of pharmaceutical and biomedical analysis, 2021, Mar-20, Volume: 196 Topics: Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Azithromycin; Chloroquine; Chromatography, Liquid; COVID-19; COVID-19 Drug Treatment; Furans; Humans; Hydroxychloroquine; Isotopes; Lopinavir; Pandemics; Pyrazines; Pyrroles; Ritonavir; SARS-CoV-2; Tandem Mass Spectrometry; Triazines	2021
Cardiac arrhythmias in COVID-19 patients: A combination of viral comorbidities and pro-arrhythmic drug interactions. The American journal of emergency medicine, 2021, Volume: 48 Topics: Angiotensin-Converting Enzyme 2; Anti-Bacterial Agents; Antimalarials; Arrhythmias, Cardiac; Azithromycin; Cardiovascular Diseases; Chloroquine; Comorbidity; COVID-19; COVID-19 Drug Treatment; Drug Interactions; Humans; Hydroxychloroquine; Long QT Syndrome; Myocytes, Cardiac; Receptors, Coronavirus; SARS-CoV-2; Torsades de Pointes	2021
COVID-19 infection in pediatric subjects: study of 36 cases in Conakry. The Pan African medical journal, 2020, Volume: 37, Issue:Suppl 1 Topics: Adolescent; Asymptomatic Infections; Azithromycin; Child; Child, Preschool; Chloroquine; COVID-19; COVID-19 Testing; Female; Guinea; Hospitalization; Humans; Infant; Male; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Tomography, X-Ray Computed; Zinc	2020
Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients? Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2021, Volume: 54, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Dietary Supplements; Female; Humans; Male; Middle Aged; SARS-CoV-2; Treatment Outcome; Young Adult; Zinc	2021
Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma. PloS one, 2021, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Antimalarials; Azithromycin; Blood Specimen Collection; Chloroquine; Chromatography, High Pressure Liquid; Drug Monitoring; Edetic Acid; Humans; Hydroxychloroquine; Limit of Detection; Tandem Mass Spectrometry	2021
COVID-19 Drugs Chloroquine and Hydroxychloroquine, but Not Azithromycin and Remdesivir, Block hERG Potassium Channels. The Journal of pharmacology and experimental therapeutics, 2021, Volume: 377, Issue:2 Topics: Adenosine Monophosphate; Alanine; Anti-Bacterial Agents; Antimalarials; Antiviral Agents; Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; ERG1 Potassium Channel; HEK293 Cells; Humans; Hydroxychloroquine; Potassium Channel Blockers	2021
Torsade de pointes associated with chloroquine, hydroxychloroquine, and azithromycin: a retrospective analysis of individual case safety reports from VigiBase. European journal of clinical pharmacology, 2021, Volume: 77, Issue:10 Topics: Adult; Aged; Azithromycin; Chloroquine; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Pharmacovigilance; Retrospective Studies; Torsades de Pointes	2021
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation. British journal of pharmacology, 2022, Volume: 179, Issue:11 Topics: Acidosis; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Hypokalemia; Induced Pluripotent Stem Cells; SARS-CoV-2	2022
Assessment of Recovery Time, Worsening, and Death among Inpatients and Outpatients with COVID-19, Treated with Hydroxychloroquine or Chloroquine plus Azithromycin Combination in Burkina Faso. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 118 Topics: Antiviral Agents; Azithromycin; Burkina Faso; Chloroquine; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Inpatients; Outpatients; SARS-CoV-2	2022
Pharmacometric and Electrocardiographic Evaluation of Chloroquine and Azithromycin in Healthy Volunteers. Clinical pharmacology and therapeutics, 2022, Volume: 112, Issue:4 Topics: Adult; Antimalarials; Azithromycin; Chloroquine; Coronavirus Infections; COVID-19 Drug Treatment; DNA-Binding Proteins; Electrocardiography; Healthy Volunteers; Humans; Hydroxychloroquine; Long QT Syndrome; Pandemics; Pneumonia, Viral; Torsades de Pointes	2022
Targeting malaria parasites with novel derivatives of azithromycin. Frontiers in cellular and infection microbiology, 2022, Volume: 12 Topics: Animals; Antimalarials; Azithromycin; Chloroquine; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum	2022
Adverse drug reactions to chloroquine/hydroxychloroquine in combination with azithromycin in COVID-19 in-patients: data from intensive pharmacovigilance in Morocco, 2020. Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:12 Topics: Azithromycin; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxychloroquine; Morocco; Pharmacovigilance	2023
Real-Life Data on Hydroxychloroquine or Chloroquine with or Without Azithromycin in COVID-19 Patients: A Retrospective Analysis in Brazil. Arquivos brasileiros de cardiologia, 2023, Volume: 120, Issue:9 Topics: Aged; Arrhythmias, Cardiac; Azithromycin; Brazil; Chloroquine; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Retrospective Studies; SARS-CoV-2	2023