chloroquine and zidovudine

chloroquine has been researched along with zidovudine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (6.67)	18.2507
2000's	13 (43.33)	29.6817
2010's	15 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gochfeld, DJ; Hamann, MT	1
Alonso, D; Donia, MS; Franzblau, SG; Garcia-Palomero, E; Hamann, MT; Khan, SI; Martinez, A; Medina, M; Peng, J; Rao, KV; Tekwani, BL; Wahyuono, S; Willett, KL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Azas, N; Casano, G; Dumètre, A; Hutter, S; Pannecouque, C; Robin, M	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chibale, K; Egan, TJ; Guantai, EM; Gut, J; Ncokazi, K; Rosenthal, PJ; Smith, PJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Aminake, MN; Chibale, K; de Kock, C; Grobler, A; Hans, R; Kirschner, M; Kumar, V; Mahajan, A; Pradel, G; Rethwilm, A; Smith, PJ; Taylor, D; Wiesner, L	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Costa, J; Dumontet, V; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Retailleau, P; Roussi, F	1
Girard-Valenciennes, E; Grondin, I; Leyssen, P; Litaudon, M; Neyts, J; Olivon, F; Palenzuela, H; Pannecouque, C; Roussi, F	1
Costa, J; Delang, L; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Renucci, F; Roussi, F	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Belda Mira, A; Díaz Sánchez, F; Michavila Gómez, J; Rovira Daudí, E	1
Andrews, W; Madhavankutty, K; Shyamasundar, K	1
Boelaert, JR; Piette, J; Sperber, K	1
Boelaert, JR; Cauda, R; Golotta, C; Lucia, MB; Morra, E; Perno, CF; Rastrelli, E; Rutella, S; Savarino, A; Sperber, K; Tamburrini, E	1
Bozzi, A; Brisdelli, F; D'Alessandro, AM; D'Andrea, G; Ippoliti, R; Lizzi, AR; Oratore, A; Pitari, G; Zeolla, N	1
Engchanil, C; Kosalaraksa, P; Lulitanond, V; Lumbiganon, P; Pongjunyakul, P; Suwan-apichon, O; Thuennadee, R; Tungsawad, S	1

Reviews

1 review(s) available for chloroquine and zidovudine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for chloroquine and zidovudine

Article	Year
Therapeutic potential of chloroquine added to zidovudine plus didanosine for HIV-1 infected children. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89, Issue:8 Topics: Anti-HIV Agents; Antimalarials; Child; Child, Preschool; Chloroquine; Didanosine; Female; HIV Infections; HIV-1; Humans; Male; Zidovudine	2006

Other Studies

28 other study(ies) available for chloroquine and zidovudine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp. Journal of natural products, 2001, Volume: 64, Issue:11 Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dioxanes; Gas Chromatography-Mass Spectrometry; Hepatitis B; HIV; Humans; Jamaica; Lactones; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Mycobacterium tuberculosis; Neoplasms, Unknown Primary; Nuclear Magnetic Resonance, Biomolecular; Plasmodium berghei; Plasmodium falciparum; Porifera; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured	2001
Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases. Journal of natural products, 2006, Volume: 69, Issue:7 Topics: Alzheimer Disease; Animals; Female; Glycogen Synthase Kinase 3; HIV-1; Humans; Indole Alkaloids; Indonesia; Inhibitory Concentration 50; Leishmania donovani; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oryzias; Plasmodium falciparum; Porifera; Structure-Activity Relationship	2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Anti-HIV and antiplasmodial activity of original flavonoid derivatives. Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16 Topics: Anti-HIV Agents; Antimalarials; Cell Line; Cell Survival; Flavonoids; HIV; HIV Infections; Humans; Malaria, Falciparum; Plasmodium falciparum	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds. Bioorganic & medicinal chemistry, 2010, Dec-01, Volume: 18, Issue:23 Topics: Alkynes; Aminoquinolines; Animals; Antimalarials; Azides; Catalysis; Chalcone; Chalcones; Copper; Drug Design; Hemin; Nucleosides; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Triazoles	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy. Bioorganic & medicinal chemistry, 2012, Sep-01, Volume: 20, Issue:17 Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Antimalarials; Dose-Response Relationship, Drug; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV-1; Humans; Malaria; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead. Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6 Topics: Alphavirus Infections; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Diterpenes; Euphorbia; France; HIV-1; HIV-2; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Semliki forest virus; Sindbis Virus; Structure-Activity Relationship; Virus Replication	2014
Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. Journal of natural products, 2015, May-22, Volume: 78, Issue:5 Topics: Antiviral Agents; Chikungunya virus; Diterpenes; Euphorbiaceae; France; HCT116 Cells; HIV-1; HIV-2; Humans; Macrocyclic Compounds; MCF-7 Cells; Molecular Structure; Semliki forest virus; Sindbis Virus; Virus Replication	2015
Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication. Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6 Topics: Anti-HIV Agents; Antiviral Agents; Chikungunya virus; Diterpenes; DNA Replication; Esters; Euphorbiaceae; HIV Infections; HIV-1; HIV-2; Molecular Structure; Phorbol Esters; Tetradecanoylphorbol Acetate; Virus Replication	2015
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Porphyria cutanea tarda and human immunodeficiency virus infection. Apropos of 2 further cases]. Revista clinica espanola, 1994, Volume: 194, Issue:7 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Drug Therapy, Combination; HIV Infections; Humans; Male; Porphyria Cutanea Tarda; Pyrimethamine; Substance-Related Disorders; Zidovudine	1994
From pseudocholinesterase to human immunodeficiency virus. Medical hypotheses, 1995, Volume: 45, Issue:3 Topics: Animals; Antibodies; Apolipoproteins E; Biochemistry; Butyrylcholinesterase; Chloroquine; Drug Carriers; Endocytosis; Enzyme Activation; HIV; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV Reverse Transcriptase; Humans; Immunoconjugates; Immunotherapy; Liposomes; Liver; Low Density Lipoprotein Receptor-Related Protein-1; Lysosomes; Mammals; Receptors, Lipoprotein; RNA-Directed DNA Polymerase; Zidovudine	1995
The additive in vitro anti-HIV-1 effect of chloroquine, when combined with zidovudine and hydroxyurea. Biochemical pharmacology, 2001, Jun-15, Volume: 61, Issue:12 Topics: Anti-HIV Agents; Chloroquine; Drug Synergism; HIV-1; Humans; Hydroxyurea; Microbial Sensitivity Tests; Zidovudine	2001
Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors. Journal of acquired immune deficiency syndromes (1999), 2004, Mar-01, Volume: 35, Issue:3 Topics: Anti-HIV Agents; Apoptosis; Cell Division; Cell Line; Cell Survival; Chloroquine; Cysteine; Drug Synergism; Glycosylation; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Methionine; Virus Replication; Zidovudine	2004
The effect of AZT and chloroquine on the activities of ricin and a saporin-transferrin chimeric toxin. Biochemical pharmacology, 2005, Aug-15, Volume: 70, Issue:4 Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chloroquine; Humans; Immunotoxins; Microscopy, Confocal; N-Glycosyl Hydrolases; Plant Proteins; Recombinant Fusion Proteins; Ribosome Inactivating Proteins, Type 1; Saporins; Transferrin; Zidovudine	2005