chloroquine and wr 99210

chloroquine has been researched along with wr 99210 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Genther, CS; Smith, CS1
Ager, AL; Bliss, RA; Canfield, CJ; Jacobus, DP; Jensen, NP; Kotecka, BM; Rieckmann, KH; Terpinski, J1
Brun, R; Chitnumsub, P; Dartois, V; Diagana, TT; Goh, A; Kamchonwongpaisan, S; Keller, TH; Kiara, SM; Lakshminarayana, SB; Ma, NL; Maneeruttanarungroj, C; Nzila, A; Rottmann, M; Taweechai, S; Weaver, M; Wittlin, S; Wong, J; Yeung, BK; Yuthavong, Y; Zou, B1
Avery, VM; Baell, JB; Duffy, S; Hutton, CA; Klonis, N; Lucantoni, L; Teguh, SC; Tilley, L1
Childs, GE; Pooyindee, N; Wimonwattrawatee, T1
Howells, RE; Judge, BM1
Hartwell, LH; Sibley, CH; Vasquez, B; Wooden, JM1

Other Studies

7 other study(ies) available for chloroquine and wr 99210

ArticleYear
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines

1977
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Animals; Antimalarials; Drug Evaluation, Preclinical; Female; Folic Acid Antagonists; Guanidines; Malaria; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Proguanil; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2001
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Drug Resistance; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Male; Mice; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinazolines; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase

2010
Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity.
    Journal of medicinal chemistry, 2013, Aug-08, Volume: 56, Issue:15

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Resistance; HEK293 Cells; Hemeproteins; Hemoglobins; Humans; Indoles; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Mitochondria; Plasmodium falciparum; Structure-Activity Relationship

2013
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
    The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines

1988
Sustained-release implants in the chemotherapy of experimental rodent malaria I. A comparison of the effects of some antimalarials in polydimethylsiloxane matrices.
    Annals of tropical medicine and parasitology, 1981, Volume: 75, Issue:5

    Topics: Animals; Antimalarials; Chloroquine; Dimethylpolysiloxanes; Drug Implants; Malaria; Male; Mefloquine; Mice; Mice, Inbred Strains; Naphthoquinones; Piperidines; Plasmodium berghei; Primaquine; Proguanil; Pyrimethamine; Quinolines; Silicone Elastomers; Sulfadiazine; Triazines

1981
Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum.
    Molecular and biochemical parasitology, 1997, Volume: 85, Issue:1

    Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Genes, Protozoan; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Recombinant Proteins; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines

1997