chloroquine has been researched along with wortmannin in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, Y; Feng, F; He, S; Jiang, X; Li, Q; Lu, X; Qu, W; Sun, H | 1 |
| McKeown-Longo, PJ; Wilkins-Port, CE | 1 |
| Dodds, RA; Drake, FH; Gowen, M; Holmes, MW; Hwang, SM; James, IE; McClung, HA; Rieman, DJ | 1 |
| Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M | 1 |
| Gamo, K; Gartler, SM; Gatti, RA; Goldstine, JV; Hansen, RS; Marahrens, Y; Nahas, S; Roelfsema, JH | 1 |
| Colonna, M; Fuchs, A; Fung-Leung, WP; Gu, Y; Karlsson, L; Lai, KT; Rao, N; Sanjuan, MA; Sun, S | 1 |
| Hällbrink, M; Jayamanne, M; Kjellander, M; Palm, C | 1 |
| Ganapathy, V; Kashiwagi, H; Sugawara, M; Takekuma, Y; Yamazaki, K | 1 |
| Dickman, MB; Kabbage, M; Williams, B | 1 |
| Bläuer, M; Hashimoto, D; Hirota, M; Ikonen, NH; Laukkarinen, J; Sand, J | 1 |
| Cao, J; Fang, Y; He, Q; Liu, L; Qi, X; Xie, N; Yang, B; Ying, M; Zhong, L | 1 |
| Bae, ON; Baek, SH; Jeong, HK; Kim, M; Kim, MJ; Kim, SE; Park, HJ | 1 |
| Barui, AK; Hu, Y; Jin, PP; Lin, J; Patra, CR; Ruan, RQ; Shi, SS; Wei, PF; Wen, LP; Zhang, HR; Zhang, JQ; Zhang, L; Zhang, YJ; Zhou, W | 1 |
| He, Y; Liu, B; Peng, H; Qi, Z; Qin, Z; Ren, H; Tang, H; Wang, S; Yves, TD; Zhao, P | 1 |
| Chen, S; Jia, P; Qi, X; Wang, J; Wang, T; Wang, X; Xue, Q; Xue, T; Yang, B | 1 |
| Caceres, SM; Grimm, XA; Malcolm, KC; Nick, JA; Poch, KR; Pohl, K; Rysavy, N; Saavedra, M | 1 |
1 review(s) available for chloroquine and wortmannin
| Article | Year |
|---|---|
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.
Topics: Animals; Autophagy; Drug Design; Humans; Small Molecule Libraries | 2018 |
18 other study(ies) available for chloroquine and wortmannin
| Article | Year |
|---|---|
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Degradation of distinct forms of multimeric vitronectin by human fibroblasts.
Topics: Alkylation; Androstadienes; Ascorbic Acid; Cells, Cultured; Chloroquine; Endocytosis; Fibroblasts; Heparin; Humans; Integrins; Lysosomes; Oligopeptides; Proteoglycans; Receptors, Vitronectin; Vitronectin; Wortmannin | 1998 |
Biosynthesis and processing of cathepsin K in cultured human osteoclasts.
Topics: Androstadienes; Antibodies; Bone Resorption; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Enzyme Inhibitors; Humans; Immunohistochemistry; Monensin; Osteoclasts; Phosphoinositide-3 Kinase Inhibitors; Protein Processing, Post-Translational; Wortmannin | 2001 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cycloheximide; Cytosol; Endosomes; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Liver Neoplasms; Metabolism; Molecular Sequence Data; Nocodazole; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; Time Factors; Wortmannin | 2003 |
Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
Topics: Abnormalities, Multiple; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chloroquine; Chromatin; DNA Damage; DNA-Binding Proteins; Female; Humans; Male; Phosphorylation; Phosphotransferases; Protein Serine-Threonine Kinases; Radiation Tolerance; Radiation, Ionizing; Serine; Syndrome; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin | 2006 |
CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion.
Topics: Actin Cytoskeleton; Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antigens, CD; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Chloroquine; CpG Islands; Cytokines; Cytoskeleton; Dendritic Cells; Humans; I-kappa B Proteins; Interferon-alpha; Interleukin-6; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Knockout; Models, Biological; Monocytes; Myeloid Differentiation Factor 88; NF-KappaB Inhibitor alpha; Oligodeoxyribonucleotides; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-hck; Pyrazoles; Pyrimidines; Quinacrine; RNA, Small Interfering; src-Family Kinases; Syk Kinase; Toll-Like Receptor 9; Tyrosine; Wortmannin | 2006 |
Peptide degradation is a critical determinant for cell-penetrating peptide uptake.
Topics: Androstadienes; Animals; Carrier Proteins; Cell Membrane; Cell-Penetrating Peptides; Chloroquine; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cytochalasin B; Deoxyglucose; Endocytosis; Leupeptins; Membrane Glycoproteins; Models, Biological; Nocodazole; Oligopeptides; Peptide Fragments; Peptides; Perforin; Phenanthrolines; Phenylmethylsulfonyl Fluoride; Pore Forming Cytotoxic Proteins; Protease Inhibitors; Protein Transport; Sodium Azide; Wortmannin | 2007 |
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Topics: Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acids; Androstadienes; Animals; Anthracenes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Flavonoids; Insulin; Insulin Antagonists; Muscle, Skeletal; Osmotic Pressure; Protein Synthesis Inhibitors; Rats; Up-Regulation; Wortmannin | 2009 |
Cell death control: the interplay of apoptosis and autophagy in the pathogenicity of Sclerotinia sclerotiorum.
Topics: Adenine; Androstadienes; Antifungal Agents; Apoptosis; Arabidopsis; Ascomycota; Autophagy; Chloroquine; Chromones; Host-Pathogen Interactions; Morpholines; Mycoses; Oxalic Acid; Plant Diseases; Reactive Oxygen Species; Respiratory Burst; Wortmannin | 2013 |
Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs.
Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Microtubule-Associated Proteins; Pancreatic Neoplasms; Protein Kinase Inhibitors; Wortmannin | 2014 |
Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells.
Topics: Androstadienes; Autophagy; Cell Differentiation; Cell Line, Tumor; Chloroquine; Chromones; Dasatinib; DNA Primers; Humans; Leukemia, Myeloid, Acute; Morpholines; Polymerase Chain Reaction; Protein Kinase Inhibitors; Pyrimidines; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Thiazoles; Up-Regulation; Wortmannin | 2014 |
Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions.
Topics: Amino Acid Chloromethyl Ketones; Amino Acids; AMP-Activated Protein Kinases; Androstadienes; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Chloroquine; Glucose; Humans; Pancreas; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Wortmannin | 2015 |
Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.
Topics: Adenine; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Butadienes; Cell Line, Tumor; Cell Survival; Chloroquine; Europium; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; HeLa Cells; Humans; Huntingtin Protein; Hydroxides; Lysosomes; Macrolides; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Nanotubes; Nerve Tissue Proteins; Neurodegenerative Diseases; Nitriles; Phagosomes; Phosphorylation; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Trehalose; Wortmannin | 2015 |
Zika Virus Induces Autophagy in Human Umbilical Vein Endothelial Cells.
Topics: Androstadienes; Animals; Autophagy; Chlorocebus aethiops; Chloroquine; Gene Knockout Techniques; Human Umbilical Vein Endothelial Cells; Humans; Phagosomes; RNA, Small Interfering; Signal Transduction; Sirolimus; Vero Cells; Virus Replication; Wortmannin; Zika Virus; Zika Virus Infection | 2018 |
Autophagy enhances the replication of Peste des petits ruminants virus and inhibits caspase-dependent apoptosis in vitro.
Topics: Ammonium Chloride; Androstadienes; Animals; Apoptosis; Autophagosomes; Autophagy; Autophagy-Related Protein 7; Beclin-1; Caspases; Chloroquine; Endometrium; Epithelial Cells; Female; Goats; Host-Pathogen Interactions; Humans; In Vitro Techniques; Lysosomes; Nucleoproteins; Peste-des-Petits-Ruminants; Peste-des-petits-ruminants virus; Protein C; Virus Replication; Wortmannin | 2018 |
Mycobacterium abscessus Clearance by Neutrophils Is Independent of Autophagy.
Topics: Adaptor Proteins, Signal Transducing; Anti-Bacterial Agents; Autophagy; Azithromycin; Case-Control Studies; Chemokine CCL4; Chloroquine; Cystic Fibrosis; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Immunosuppressive Agents; Interleukin-8; Mycobacterium abscessus; Neutrophils; Phagocytosis; Primary Cell Culture; Reactive Oxygen Species; Signal Transduction; Sirolimus; Wortmannin | 2020 |