chloroquine and warfarin

chloroquine has been researched along with warfarin in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's0 (0.00)18.2507
2000's7 (24.14)29.6817
2010's11 (37.93)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Ndove, J; Nsumiwa, S; Okombo, J; Taylor, D; Wiesner, L1
Bia, FJ; Divo, AA; Patton, CL; Sartorelli, AC1
Cepelák, V; Grimová, J; Nĕmecek, O; Roubal, Z1
Holmes, J; Sapeika, N; Zwarenstein, H2
Barg, TsM1
Post, D1
Chai, HB; Cordell, GA; Lee, KH; Pezzuto, JM; Tamez, PA; Tin-Wa, M; Win, KK1
EL-MOFTY, AM1
Caldas, CA; de Carvalho, JF1
Abegaz, B; Bezabih, M; Hayeshi, R; Mangoyi, R; Mukanganyama, S; Ngadjui, B; Ngandeu, F; Rasoanaivo, P; Razafimahefa, S1
Ansari, ZA; Chakrabarti, P; Chakraborty, S; Dey, S; Joshi, P; Shanker, V; Singh, SP1
Kang, J; Li, X; Mao, X; Tian, Y; Tuohetaerbaike, B; Zhang, NN; Zhang, Y1
Aisker, G; Dong, H; Halemahebai, G; Tian, L; Zhang, Y1
Carrico-Moniz, D; Kusaka, E; Wang, Y; Webb, A; Zhang, J; Zhou, R1

Reviews

2 review(s) available for chloroquine and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
    Oftalmologicheskii zhurnal, 1969, Volume: 24, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalarials; Cardiac Glycosides; Cataract; Child; Chloroquine; Chlorpromazine; Epinephrine; Ethambutol; Ethchlorvynol; Eye Diseases; Female; Humans; Miotics; Nalidixic Acid; Phosphates; Pilocarpine; Quinolines; Retinal Degeneration; Warfarin

1969

Other Studies

27 other study(ies) available for chloroquine and warfarin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeability; Chloroquine; CHO Cells; Cricetulus; Drug Evaluation, Preclinical; Drug Resistance, Microbial; ERG1 Potassium Channel; Hemeproteins; Humans; Malaria; Male; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Solubility; Structure-Activity Relationship

2017
Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8

    Topics: Aminocoumarins; Animals; Anti-Infective Agents; Chloroquine; Ciprofloxacin; Coumarins; Drug Interactions; Drug Resistance; Enoxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Novobiocin; Ofloxacin; Oxolinic Acid; Pefloxacin; Plasmodium falciparum; Tetracycline; Topoisomerase II Inhibitors

1988
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depression, Chemical; Dicumarol; Erythrocytes; Fibrinolysis; Flufenamic Acid; Hemolysis; Humans; Hypotonic Solutions; In Vitro Techniques; Indomethacin; Inflammation; Mefenamic Acid; Oxyphenbutazone; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Pyrazoles; Receptors, Drug; Structure-Activity Relationship

1972
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1

    Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin

1974
Lysosomes--a pipe-dream come true.
    Food and cosmetics toxicology, 1968, Volume: 6, Issue:6

    Topics: Chloroquine; Coumarins; Glycosaminoglycans; Lipids; Liver; Lysosomes

1968
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts

1973
[Documentation in the toxicological laboratory. Practical identification of substances by means of punched feature cards].
    Beitrage zur gerichtlichen Medizin, 1969, Volume: 26

    Topics: Child; Chloroquine; Chromatography, Thin Layer; Coumarins; Forensic Medicine; Humans; Indicators and Reagents; Pharmaceutical Preparations; Phenacetin; Punched-Card Systems; Spectrum Analysis; Ultraviolet Rays

1969
Biologically active alkylated coumarins from Kayea assamica.
    Phytochemistry, 2003, Volume: 64, Issue:2

    Topics: Alkylation; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Chloroquine; Clusiaceae; Coumarins; Drug Screening Assays, Antitumor; Humans; KB Cells; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Myanmar; Plant Bark; Plants, Medicinal; Plasmodium falciparum; Tumor Cells, Cultured

2003
THE TREATMENT OF VITILIGO WITH A COMBINATION OF PSORALENS AND QUINOLINES.
    The British journal of dermatology, 1964, Volume: 76

    Topics: Amodiaquine; Chloroquine; Copper; Coumarins; Dermatitis, Phototoxic; Furocoumarins; Humans; Iron; Photosensitivity Disorders; Quinolines; Sunlight; Toxicology; Ultraviolet Rays; Vitiligo

1964
Primary antiphospholipid syndrome with and without Sneddon's syndrome.
    Rheumatology international, 2011, Volume: 31, Issue:2

    Topics: Adult; Antiphospholipid Syndrome; Aspirin; Autoantibodies; Chloroquine; Female; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Prevalence; Sneddon Syndrome; Treatment Outcome; Venous Thrombosis; Warfarin

2011
Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:6

    Topics: Alkaloids; Biological Products; Chloroquine; Coumarins; Curcumin; Dinitrochlorobenzene; Drug Discovery; Drug Resistance; Ellagic Acid; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Kinetics; Malaria, Falciparum; Plants, Medicinal; Plasmodium falciparum; Protozoan Proteins; Recombinant Proteins; Sesquiterpenes, Germacrane

2010
Binding of chloroquine-conjugated gold nanoparticles with bovine serum albumin.
    Journal of colloid and interface science, 2011, Mar-15, Volume: 355, Issue:2

    Topics: Animals; Antimalarials; Binding Sites; Borohydrides; Cattle; Chloroquine; Fatty Acids; Gold; Microscopy, Electron, Transmission; Models, Molecular; Nanoparticles; Particle Size; Protein Binding; Protein Structure, Tertiary; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds; Thermodynamics; Tryptophan; Warfarin

2011
Pancreas protective effects of Urolithin A on type 2 diabetic mice induced by high fat and streptozotocin via regulating autophagy and AKT/mTOR signaling pathway.
    Journal of ethnopharmacology, 2020, Mar-25, Volume: 250

    Topics: Animals; Autophagy; Blood Glucose; Chloroquine; Coumarins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Male; Mice; Mice, Inbred C57BL; Pancreas; Proto-Oncogene Proteins c-akt; Signal Transduction; Streptozocin; TOR Serine-Threonine Kinases

2020
Urolithin A, a pomegranate metabolite, protects pancreatic β cells from apoptosis by activating autophagy.
    Journal of ethnopharmacology, 2021, May-23, Volume: 272

    Topics: Animals; Apoptosis; Autophagy; Cell Line; Cell Survival; Chloroquine; Coumarins; Diabetes Mellitus, Experimental; Glucose; Insulin-Secreting Cells; Lipids; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Pomegranate; Protective Agents

2021
Isoprenylated Coumarin Exhibits Anti-proliferative Effects in Pancreatic Cancer Cells Under Nutrient Starvation by Inhibiting Autophagy.
    Anticancer research, 2022, Volume: 42, Issue:6

    Topics: Adenocarcinoma; Autophagy; Cell Line, Tumor; Chloroquine; Coumarins; Glucose; Humans; Nutrients; Pancreatic Neoplasms

2022