Compounds > chloroquine

chloroquine and ubenimex

chloroquine has been researched along with ubenimex in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Deprez-Poulain, R; Flipo, M; Florent, I; Grellier, P; Sergheraert, C1
Andrews, KT; Gardiner, DL; McCarthy, J; Melville, L; Skinner-Adams, TS1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cos, P; Dassonneville, S; Deprez, B; Deprez-Poulain, R; Flipo, M; Florent, I; Leroux, F; Maes, L; Piveteau, C1
Alonso Del Rivero, M; Budu, A; Carmona, AK; Ferreira, JC; Florent, I; Gazarini, ML; González-Bacerio, J; Maluf, SEC; Melo, PMS; Méndez, Y; Moreno, E; Pascual, I; Rivera, DG1
Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB1
Ariefta, NR; Hatano, M; Igarashi, M; Ikeda, N; Isshiki, K; Matoba, K; Nihei, CI; Nishikawa, Y; Pagmadulam, B1
Dalton, JP; Gardiner, DL; Grembecka, J; Kafarski, P; Lowther, J; Mucha, A; Skinner-Adams, TS; Stack, CM; Teuscher, F; Trenholme, KR1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

9 other study(ies) available for chloroquine and ubenimex

ArticleYear
Design, synthesis and antimalarial activity of novel, quinoline-based, zinc metallo-aminopeptidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Aminopeptidases; Animals; Antimalarials; Drug Design; Enzyme Inhibitors; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Zinc

2003
Synergistic interactions of the antiretroviral protease inhibitors saquinavir and ritonavir with chloroquine and mefloquine against Plasmodium falciparum in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; Drug Synergism; HIV Protease Inhibitors; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Ritonavir; Saquinavir

2007
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors.
    Journal of medicinal chemistry, 2012, Dec-27, Volume: 55, Issue:24

    Topics: Aminopeptidases; Animals; Antimalarials; Cell Line; Drug Resistance; Female; Humans; Malaria; Malonates; Metalloproteases; Mice; Molecular Docking Simulation; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Rats; Solubility; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Zinc

2012
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Antimalarials; Binding Sites; Catalytic Domain; CD13 Antigens; Cell Survival; Dipeptides; Erythrocytes; Human Umbilical Vein Endothelial Cells; Humans; Leucine; Molecular Docking Simulation; Peptidomimetics; Plasmodium falciparum; Protozoan Proteins; Recombinant Proteins; Structure-Activity Relationship

2017
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship

2019
Antiplasmodial Activity Evaluation of a Bestatin-Related Aminopeptidase Inhibitor, Phebestin.
    Antimicrobial agents and chemotherapy, 2023, 07-18, Volume: 67, Issue:7

    Topics: Aminopeptidases; Animals; Antimalarials; Chloroquine; Humans; Malaria; Malaria, Falciparum; Mice; Parasitemia; Plasmodium berghei; Plasmodium falciparum

2023
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Amino Acid Sequence; Animals; Antimalarials; Dipeptides; Kinetics; Leucine; Leucyl Aminopeptidase; Models, Molecular; Molecular Sequence Data; Phosphinic Acids; Plasmodium chabaudi; Plasmodium falciparum; Recombinant Proteins; Structure-Activity Relationship

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009